FB2022_02, released March 29, 2022

Gene: Dmel\ham

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General Information
Symbol
Dmel\ham
Species
D. melanogaster
Name
hamlet
Annotation Symbol
CG31753
Feature Type
protein_coding_gene
FlyBase ID
FBgn0045852
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Summary
hamlet (ham) encodes a PRDM family transcription factor that regulates neuron fate selection in the peripheral nervous system and olfactory receptor neurons. It also controls intermediate precursor cell maturation in the type II neuroblast lineages of the larval brain. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Key Links
Genomic Location
Cytogenetic map
37A2-37A3
Sequence location
Recombination map
2-54
RefSeq locus
NT_033779 REGION:18762874..18792906
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables DNA-binding transcription factor activity
inferred from mutant phenotype
(assigned by UniProt )
(Moore et al., 2004)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables DNA-binding transcription activator activity, RNA polymerase II-specific
inferred from biological aspect of ancestor with PANTHER:PTN002811836
(assigned by GO_Central )
(Gaudet et al., 2011)
enables histone methyltransferase activity (H3-K9 specific)
inferred from sequence or structural similarity with UniProtKB:P14404
(FlyBase Curators, 2008-)
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN002811836
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (6 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
involved_in negative regulation of cell population proliferation
inferred from mutant phenotype
(Eroglu et al., 2014)
involved_in neuroblast fate commitment
inferred from mutant phenotype
(Eroglu et al., 2014)
involved_in regulation of dendrite development
inferred from mutant phenotype
(assigned by UniProt )
(Moore et al., 2004, Moore et al., 2002)
involved_in regulation of transcription, DNA-templated
inferred from mutant phenotype
(assigned by UniProt )
(Moore et al., 2004)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in dendrite morphogenesis
traceable author statement
(Grueber and Jan, 2004)
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN002811836
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(assigned by UniProt )
(Moore et al., 2002)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN002811836
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in nucleus
traceable author statement
(Gao and Bogert, 2003)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
hamlet (ham) encodes a PRDM family transcription factor that regulates neuron fate selection in the peripheral nervous system and olfactory receptor neurons. It also controls intermediate precursor cell maturation in the type II neuroblast lineages of the larval brain. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
OTHER PROTEIN-LYSINE N-METHYLTRANSFERASES -
The 'Other protein-lysine N-methyltransferases' is a collection of protein-lysine N-methyltransferases that do not fit into any of the other major groups.
Protein Function (UniProtKB)
Transcription factor that plays a crucial role in external sensory organ (ESO) that elaborates from a single precursor cell (ESOP cell). Mediates the differentiation of lineage branch that generates the internal 'ES' and 'th' cells (external sensory neuron and thecogen cells, respectively) from the IIIB cell. Its absence leads to re-specification of IIIB daughter cells into external tormagen cells (tr cells), or internal multidendritic neurons (MD cells). One of its role in the development of the ESO lineage is to modulate the activity of Notch and PAX2 signals.
(UniProt, Q8I7Z8)
Summary (Interactive Fly)

zinc finger - regulates cell identity in the peripheral nervous system - a binary genetic switch that acts to repress a multiple dendritic arbor and promote single-dendrite morphology - controls nociceptive behavior in sensory neurons

Gene Model and Products
Number of Transcripts
5
Number of Unique Polypeptides
4

Please see the JBrowse view of Dmel\ham for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure New Section
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q8I7Z8)

If you don't see the viewer to the right, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.45

Gene model reviewed during 6.32

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
ham-RB
FBtr0305620
NM_001259152
4242
990
ham-RD
FBtr0332015
NM_001273614
4574
990
ham-RE
FBtr0332016
NM_001273615
3207
633
ham-RG
FBtr0479832
NM_165262
4243
1108
ham-RH
FBtr0479833
NM_001273616
4111
1064
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
ham-PB
FBpp0294066
109.2
990
7.35
NP_001246081
AFH03755
ham-PD
FBpp0304333
109.2
990
7.35
NP_001260543
AGB93078
ham-PE
FBpp0304334
69.2
633
7.35
NP_001260544
AGB93079
ham-PG
FBpp0428166
122.4
1108
7.01
AAF53703
ham-PH
FBpp0428167
117.3
1064
7.07
AGB93080
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

990 aa isoforms: ham-PB, ham-PD
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ham using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 5
organism | 80-90% egg length | ventral
(Moore et al., 2002)
embryonic stage 5 -- 15
procephalic neurogenic region
• nucleus
(Moore et al., 2002)
embryonic stage 11 -- 15
presumptive embryonic/larval peripheral nervous system
• nucleus
(Moore et al., 2002)
external sensory organ precursor cell IIIb
• nucleus
(Moore et al., 2002)
embryonic stage 12
dorsal abdominal cluster
• nucleus

Comment: weak expression

(Moore et al., 2002)
dorsal thoracic cluster
• nucleus

Comment: weak expression

(Moore et al., 2002)
lateral abdominal cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
lateral thoracic cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
embryonic stage 13
dorsal abdominal cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
dorsal thoracic cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
lateral abdominal cluster
• nucleus

Comment: weak expression

(Moore et al., 2002)
lateral thoracic cluster
• nucleus

Comment: weak expression

(Moore et al., 2002)
ventral abdominal cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
ventral thoracic cluster
• nucleus

Comment: strong expression

(Moore et al., 2002)
embryonic stage 14 -- 15
thecogen cell of dorsal thoracic cluster
• nucleus
(Moore et al., 2002)
thecogen cell of dorsal abdominal cluster
• nucleus
(Moore et al., 2002)
embryonic stage 14 -- 17
eo neuron of dorsal thoracic cluster
• nucleus
(Moore et al., 2002)
eo neuron of dorsal abdominal cluster
• nucleus
(Moore et al., 2002)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
organism
(Moore et al., 2002)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(assigned by UniProt )
(Moore et al., 2002)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\ham in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 17 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of ham
Transgenic constructs containing regulatory region of ham
Aberrations (Deficiencies and Duplications) ( 5 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
abnormal cell number | larval stage, with Scer\GAL4wor.PA, Scer\GAL80ase.PN
abnormal neuroanatomy
abnormal neuroanatomy, with Scer\GAL4109(2)80
abnormal neuroanatomy, with Scer\GAL4elav.PLu
abnormal neuroanatomy, with Scer\GAL4pros.PMG
abnormal neuroanatomy | adult stage (with Df(2L)ED1195)
abnormal neuroanatomy | adult stage | somatic clone
abnormal neuroanatomy | larval stage
abnormal pain response | third instar larval stage
abnormal pain response | third instar larval stage, with Scer\GAL4ppk.1.9
abnormal sensory perception | third instar larval stage
abnormal sensory perception | third instar larval stage, with Scer\GAL4ppk.1.9
decreased cell number, with Scer\GAL4ase.neuro, Scer\GAL80ts.αTub84B
decreased cell number, with Scer\GAL4pnt-14-94, Scer\GAL80ts.αTub84B
decreased cell size, with Scer\GAL4ase.neuro, Scer\GAL80ts.αTub84B
decreased cell size, with Scer\GAL4pnt-14-94, Scer\GAL80ts.αTub84B
increased cell number | dominant | larval stage
increased cell number | larval stage, with Scer\GAL4wor.PA
increased cell number | larval stage, with Scer\GAL4wor.PA, Scer\GAL80ase.PN
increased cell number | larval stage (with Df(2L)Exel7071)
increased cell number | larval stage | somatic clone
visible, with Scer\GAL4neur-GAL4-A101
visible, with Scer\GAL4sca-109-68
visible | adult stage, with Scer\GAL4sca-109-68
Phenotype manifest in
Allele
abdominal ventral campaniform sensillum vc4a
adult olfactory receptor neuron Or2a | somatic clone
adult olfactory receptor neuron Or10a | somatic clone
adult olfactory receptor neuron Or42a | somatic clone
adult olfactory receptor neuron Or43a | somatic clone
adult olfactory receptor neuron Or43b | somatic clone
adult olfactory receptor neuron Or46a | somatic clone
adult olfactory receptor neuron Or47b | somatic clone
adult olfactory receptor neuron Or56a | somatic clone
adult olfactory receptor neuron Or59c | somatic clone
adult olfactory receptor neuron Or67a | somatic clone
adult olfactory receptor neuron Or67b | somatic clone
adult olfactory receptor neuron Or67c (with Df(2L)ED1195)
adult olfactory receptor neuron Or67c | somatic clone
adult olfactory receptor neuron Or67d | somatic clone
adult olfactory receptor neuron Or82a | somatic clone
adult olfactory receptor neuron Or83c | somatic clone
adult olfactory receptor neuron Or85a | somatic clone
adult olfactory receptor neuron Or85b/98b | somatic clone
adult olfactory receptor neuron Or88a | somatic clone
adult olfactory receptor neuron Or92a | somatic clone
adult olfactory receptor neuron Or98a | somatic clone
antennal basiconic sensillum ab6 | somatic clone
antennal coeloconic sensillum ac1 | somatic clone
antennal coeloconic sensillum ac3 | somatic clone
antennal coeloconic sensillum ac4 | somatic clone
chaeta, with Scer\GAL4neur-GAL4-A101
dorsal abdominal cluster
embryonic/larval brain | larval stage
embryonic/larval brain | larval stage, with Scer\GAL4wor.PA
embryonic/larval brain | larval stage, with Scer\GAL4wor.PA, Scer\GAL80ase.PN
embryonic/larval brain | larval stage (with Df(2L)Exel7071)
embryonic/larval brain | larval stage | somatic clone
embryonic/larval nervous system
embryonic/larval nervous system | somatic clone
eo neuron
eo neuron | increased number, with Scer\GAL4pros.PMG
eo neuron | somatic clone
ganglion mother cell | increased number, with Scer\GAL4GMR9D11
multidendritic neuron
multidendritic neuron, with Scer\GAL4109(2)80
multidendritic neuron, with Scer\GAL4elav.PLu
multidendritic neuron, with Scer\GAL4pros.PMG
multidendritic neuron | ectopic | somatic clone
multidendritic neuron | increased number
multidendritic neuron | somatic clone
notal microchaeta | adult stage, with Scer\GAL4sca-109-68
secondary neuroblast, with Scer\GAL4insc-Mz1407
secondary neuroblast | increased number, with Scer\GAL4GMR9D11
secondary neuroblast | somatic clone | increased number
tormogen cell, with Scer\GAL4neur-GAL4-A101
tormogen cell, with Scer\GAL4sca-109-68
tormogen cell | adult stage, with Scer\GAL4sca-109-68
tormogen cell | adult stage | ectopic | somatic clone
trichogen cell, with Scer\GAL4neur-GAL4-A101
trichogen cell, with Scer\GAL4sca-109-68
trichogen cell | adult stage | ectopic, with Scer\GAL4sca-109-68
trichogen cell | adult stage | ectopic | somatic clone
trichogen cell | ectopic | larval stage
trichogen cell | increased number
type II neuroblast, with Scer\GAL4pnt-14-94, Scer\GAL80ts.αTub84B
type II neuroblast | increased number | larval stage
type II neuroblast | increased number | larval stage, with Scer\GAL4wor.PA
type II neuroblast | increased number | larval stage, with Scer\GAL4wor.PA, Scer\GAL80ase.PN
type II neuroblast | increased number | larval stage (with Df(2L)Exel7071)
type II neuroblast | increased number | larval stage | somatic clone
type II neuroblast | larval stage, with Scer\GAL4wor.PA, Scer\GAL80ase.PN
type I neuroblast, with Scer\GAL4ase.neuro, Scer\GAL80ts.αTub84B
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (308)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\MECOM
12 of 15
Yes
Yes
Hsap\PRDM16
10 of 15
No
Yes
Hsap\ZFP62
2 of 15
No
Yes
Hsap\ZNF85
2 of 15
No
Yes
Hsap\ZNF91
2 of 15
No
Yes
Hsap\ZNF99
2 of 15
No
Yes
Hsap\ZNF107
2 of 15
No
Yes
Hsap\ZNF160
2 of 15
No
Yes
Hsap\ZNF208
2 of 15
No
Yes
Hsap\ZNF211
2 of 15
No
Yes
Hsap\ZNF260
2 of 15
No
Yes
1  
Hsap\ZNF347
2 of 15
No
Yes
Hsap\ZNF587
2 of 15
No
Yes
Hsap\ZNF605
2 of 15
No
Yes
Hsap\ZNF624
2 of 15
No
Yes
Hsap\ZNF658
2 of 15
No
Yes
Hsap\ZNF676
2 of 15
No
Yes
Hsap\ZNF721
2 of 15
No
Yes
Hsap\ZNF729
2 of 15
No
Yes
Hsap\ZNF780B
2 of 15
No
Yes
Hsap\ZNF808
2 of 15
No
Yes
Hsap\ZNF836
2 of 15
No
Yes
Hsap\ZNF841
2 of 15
No
Yes
Hsap\ZNF850
2 of 15
No
Yes
Hsap\ZNF883
2 of 15
No
Yes
Hsap\ERV3-1-ZNF117
1 of 15
No
Yes
Hsap\KLF10
1 of 15
No
No
Hsap\MZF1
1 of 15
No
No
Hsap\PRDM9
1 of 15
No
Yes
Hsap\RBAK-RBAKDN
1 of 15
No
Yes
Hsap\ZFP2
1 of 15
No
No
Hsap\ZFP3
1 of 15
No
Yes
Hsap\ZFP14
1 of 15
No
No
Hsap\ZFP28
1 of 15
No
No
Hsap\ZFP30
1 of 15
No
No
Hsap\ZFP37
1 of 15
No
No
Hsap\ZFP69B
1 of 15
No
No
Hsap\ZFP82
1 of 15
No
No
Hsap\ZFP90
1 of 15
No
No
Hsap\ZIK1
1 of 15
No
No
Hsap\ZIM3
1 of 15
No
No
Hsap\ZKSCAN5
1 of 15
No
No
Hsap\ZKSCAN7
1 of 15
No
No
Hsap\ZNF2
1 of 15
No
No
Hsap\ZNF3
1 of 15
No
Yes
Hsap\ZNF7
1 of 15
No
No
Hsap\ZNF10
1 of 15
No
No
Hsap\ZNF12
1 of 15
No
No
Hsap\ZNF14
1 of 15
No
Yes
Hsap\ZNF16
1 of 15
No
No
Hsap\ZNF17
1 of 15
No
No
Hsap\ZNF19
1 of 15
No
No
Hsap\ZNF20
1 of 15
No
No
Hsap\ZNF23
1 of 15
No
No
Hsap\ZNF25
1 of 15
No
No
Hsap\ZNF26
1 of 15
No
No
Hsap\ZNF28
1 of 15
No
No
Hsap\ZNF30
1 of 15
No
No
Hsap\ZNF33A
1 of 15
No
Yes
Hsap\ZNF33B
1 of 15
No
Yes
Hsap\ZNF34
1 of 15
No
No
Hsap\ZNF35
1 of 15
No
No
Hsap\ZNF37A
1 of 15
No
No
Hsap\ZNF41
1 of 15
No
No
1  
Hsap\ZNF43
1 of 15
No
Yes
Hsap\ZNF44
1 of 15
No
Yes
Hsap\ZNF45
1 of 15
No
No
Hsap\ZNF57
1 of 15
No
Yes
Hsap\ZNF66
1 of 15
No
Yes
Hsap\ZNF69
1 of 15
No
No
Hsap\ZNF70
1 of 15
No
No
Hsap\ZNF71
1 of 15
No
No
Hsap\ZNF74
1 of 15
No
No
Hsap\ZNF77
1 of 15
No
No
Hsap\ZNF79
1 of 15
No
Yes
Hsap\ZNF81
1 of 15
No
No
Hsap\ZNF83
1 of 15
No
Yes
Hsap\ZNF84
1 of 15
No
No
Hsap\ZNF90
1 of 15
No
Yes
Hsap\ZNF92
1 of 15
No
Yes
Hsap\ZNF93
1 of 15
No
No
Hsap\ZNF98
1 of 15
No
No
Hsap\ZNF100
1 of 15
No
Yes
Hsap\ZNF112
1 of 15
No
Yes
Hsap\ZNF132
1 of 15
No
No
Hsap\ZNF133
1 of 15
No
No
Hsap\ZNF135
1 of 15
No
No
Hsap\ZNF136
1 of 15
No
No
Hsap\ZNF140
1 of 15
No
No
Hsap\ZNF141
1 of 15
No
Yes
Hsap\ZNF154
1 of 15
No
No
Hsap\ZNF155
1 of 15
No
No
Hsap\ZNF157
1 of 15
No
Yes
Hsap\ZNF169
1 of 15
No
Yes
Hsap\ZNF175
1 of 15
No
No
Hsap\ZNF177
1 of 15
No
No
Hsap\ZNF180
1 of 15
No
No
Hsap\ZNF181
1 of 15
No
No
Hsap\ZNF182
1 of 15
No
No
Hsap\ZNF184
1 of 15
No
No
Hsap\ZNF189
1 of 15
No
No
Hsap\ZNF195
1 of 15
No
No
Hsap\ZNF214
1 of 15
No
No
Hsap\ZNF221
1 of 15
No
Yes
Hsap\ZNF224
1 of 15
No
Yes
Hsap\ZNF225
1 of 15
No
Yes
Hsap\ZNF226
1 of 15
No
No
Hsap\ZNF227
1 of 15
No
No
Hsap\ZNF229
1 of 15
No
Yes
Hsap\ZNF233
1 of 15
No
No
Hsap\ZNF234
1 of 15
No
No
Hsap\ZNF235
1 of 15
No
No
Hsap\ZNF236
1 of 15
No
No
Hsap\ZNF248
1 of 15
No
No
Hsap\ZNF250
1 of 15
No
No
Hsap\ZNF251
1 of 15
No
No
Hsap\ZNF253
1 of 15
No
Yes
Hsap\ZNF254
1 of 15
No
No
Hsap\ZNF256
1 of 15
No
No
Hsap\ZNF257
1 of 15
No
Yes
Hsap\ZNF264
1 of 15
No
No
Hsap\ZNF266
1 of 15
No
No
Hsap\ZNF267
1 of 15
No
Yes
1  
Hsap\ZNF268
1 of 15
No
Yes
Hsap\ZNF273
1 of 15
No
Yes
Hsap\ZNF283
1 of 15
No
No
Hsap\ZNF284
1 of 15
No
Yes
Hsap\ZNF285
1 of 15
No
No
Hsap\ZNF286A
1 of 15
No
No
Hsap\ZNF286B
1 of 15
No
No
Hsap\ZNF287
1 of 15
No
No
Hsap\ZNF300
1 of 15
No
No
Hsap\ZNF304
1 of 15
No
No
Hsap\ZNF311
1 of 15
No
No
Hsap\ZNF317
1 of 15
No
No
Hsap\ZNF320
1 of 15
No
No
Hsap\ZNF329
1 of 15
No
No
Hsap\ZNF331
1 of 15
No
Yes
Hsap\ZNF333
1 of 15
No
No
Hsap\ZNF334
1 of 15
No
No
Hsap\ZNF337
1 of 15
No
Yes
Hsap\ZNF345
1 of 15
No
Yes
Hsap\ZNF354A
1 of 15
No
No
Hsap\ZNF354B
1 of 15
No
No
Hsap\ZNF354C
1 of 15
No
No
Hsap\ZNF355P
1 of 15
No
No
Hsap\ZNF382
1 of 15
No
Yes
Hsap\ZNF383
1 of 15
No
No
Hsap\ZNF404
1 of 15
No
No
Hsap\ZNF415
1 of 15
No
No
Hsap\ZNF416
1 of 15
No
No
Hsap\ZNF417
1 of 15
No
No
Hsap\ZNF418
1 of 15
No
No
Hsap\ZNF419
1 of 15
No
No
Hsap\ZNF420
1 of 15
No
No
Hsap\ZNF425
1 of 15
No
No
Hsap\ZNF426
1 of 15
No
No
Hsap\ZNF429
1 of 15
No
No
Hsap\ZNF430
1 of 15
No
Yes
Hsap\ZNF431
1 of 15
No
Yes
Hsap\ZNF432
1 of 15
No
Yes
Hsap\ZNF433
1 of 15
No
Yes
Hsap\ZNF436
1 of 15
No
No
Hsap\ZNF439
1 of 15
No
No
Hsap\ZNF440
1 of 15
No
No
Hsap\ZNF441
1 of 15
No
Yes
Hsap\ZNF442
1 of 15
No
Yes
Hsap\ZNF443
1 of 15
No
Yes
Hsap\ZNF454
1 of 15
No
No
Hsap\ZNF460
1 of 15
No
No
Hsap\ZNF461
1 of 15
No
No
Hsap\ZNF468
1 of 15
No
Yes
Hsap\ZNF470
1 of 15
No
No
Hsap\ZNF471
1 of 15
No
No
Hsap\ZNF473
1 of 15
No
No
Hsap\ZNF479
1 of 15
No
Yes
Hsap\ZNF480
1 of 15
No
No
Hsap\ZNF483
1 of 15
No
No
Hsap\ZNF484
1 of 15
No
Yes
Hsap\ZNF485
1 of 15
No
Yes
Hsap\ZNF486
1 of 15
No
Yes
Hsap\ZNF490
1 of 15
No
No
Hsap\ZNF491
1 of 15
No
No
Hsap\ZNF492
1 of 15
No
No
Hsap\ZNF493
1 of 15
No
No
Hsap\ZNF497
1 of 15
No
No
Hsap\ZNF502
1 of 15
No
Yes
Hsap\ZNF506
1 of 15
No
Yes
Hsap\ZNF510
1 of 15
No
Yes
Hsap\ZNF519
1 of 15
No
Yes
Hsap\ZNF527
1 of 15
No
No
Hsap\ZNF528
1 of 15
No
No
Hsap\ZNF529
1 of 15
No
No
Hsap\ZNF530
1 of 15
No
No
Hsap\ZNF534
1 of 15
No
No
Hsap\ZNF540
1 of 15
No
No
Hsap\ZNF543
1 of 15
No
No
Hsap\ZNF544
1 of 15
No
No
Hsap\ZNF546
1 of 15
No
No
Hsap\ZNF548
1 of 15
No
No
Hsap\ZNF549
1 of 15
No
No
Hsap\ZNF551
1 of 15
No
No
Hsap\ZNF555
1 of 15
No
No
Hsap\ZNF559
1 of 15
No
No
Hsap\ZNF559-ZNF177
1 of 15
No
No
Hsap\ZNF560
1 of 15
No
No
Hsap\ZNF561
1 of 15
No
No
Hsap\ZNF563
1 of 15
No
Yes
Hsap\ZNF564
1 of 15
No
No
Hsap\ZNF565
1 of 15
No
No
Hsap\ZNF566
1 of 15
No
No
Hsap\ZNF567
1 of 15
No
No
Hsap\ZNF568
1 of 15
No
No
Hsap\ZNF569
1 of 15
No
No
Hsap\ZNF570
1 of 15
No
No
Hsap\ZNF571
1 of 15
No
No
Hsap\ZNF572
1 of 15
No
Yes
Hsap\ZNF573
1 of 15
No
No
Hsap\ZNF578
1 of 15
No
No
Hsap\ZNF580
1 of 15
No
Yes
Hsap\ZNF582
1 of 15
No
No
Hsap\ZNF583
1 of 15
No
No
Hsap\ZNF585A
1 of 15
No
No
Hsap\ZNF585B
1 of 15
No
Yes
Hsap\ZNF594
1 of 15
No
No
Hsap\ZNF595
1 of 15
No
No
Hsap\ZNF596
1 of 15
No
No
Hsap\ZNF599
1 of 15
No
No
Hsap\ZNF600
1 of 15
No
Yes
Hsap\ZNF606
1 of 15
No
Yes
Hsap\ZNF607
1 of 15
No
No
Hsap\ZNF611
1 of 15
No
No
Hsap\ZNF613
1 of 15
No
No
Hsap\ZNF614
1 of 15
No
No
Hsap\ZNF615
1 of 15
No
Yes
Hsap\ZNF616
1 of 15
No
No
Hsap\ZNF619
1 of 15
No
No
Hsap\ZNF623
1 of 15
No
No
Hsap\ZNF626
1 of 15
No
Yes
Hsap\ZNF627
1 of 15
No
Yes
Hsap\ZNF628
1 of 15
No
No
Hsap\ZNF629
1 of 15
No
Yes
Hsap\ZNF630
1 of 15
No
No
Hsap\ZNF649
1 of 15
No
Yes
Hsap\ZNF658B
1 of 15
No
Yes
Hsap\ZNF660-ZNF197
1 of 15
No
Yes
Hsap\ZNF665
1 of 15
No
No
Hsap\ZNF667
1 of 15
No
No
Hsap\ZNF671
1 of 15
No
No
Hsap\ZNF674
1 of 15
No
No
Hsap\ZNF675
1 of 15
No
No
Hsap\ZNF677
1 of 15
No
No
Hsap\ZNF678
1 of 15
No
No
Hsap\ZNF680
1 of 15
No
No
Hsap\ZNF681
1 of 15
No
No
Hsap\ZNF682
1 of 15
No
Yes
Hsap\ZNF695
1 of 15
No
Yes
Hsap\ZNF696
1 of 15
No
Yes
Hsap\ZNF699
1 of 15
No
No
Hsap\ZNF700
1 of 15
No
No
Hsap\ZNF708
1 of 15
No
No
Hsap\ZNF709
1 of 15
No
Yes
Hsap\ZNF714
1 of 15
No
Yes
Hsap\ZNF716
1 of 15
No
Yes
Hsap\ZNF717
1 of 15
No
No
Hsap\ZNF718
1 of 15
No
Yes
Hsap\ZNF723
1 of 15
No
Yes
Hsap\ZNF724
1 of 15
No
No
Hsap\ZNF726
1 of 15
No
No
Hsap\ZNF727
1 of 15
No
No
Hsap\ZNF728
1 of 15
No
No
Hsap\ZNF730
1 of 15
No
Yes
Hsap\ZNF732
1 of 15
No
Yes
Hsap\ZNF737
1 of 15
No
No
Hsap\ZNF749
1 of 15
No
No
Hsap\ZNF765
1 of 15
No
No
Hsap\ZNF765-ZNF761
1 of 15
No
Yes
Hsap\ZNF766
1 of 15
No
Yes
Hsap\ZNF773
1 of 15
No
No
Hsap\ZNF774
1 of 15
No
No
Hsap\ZNF776
1 of 15
No
No
Hsap\ZNF778
1 of 15
No
Yes
Hsap\ZNF780A
1 of 15
No
No
Hsap\ZNF782
1 of 15
No
No
Hsap\ZNF790
1 of 15
No
No
Hsap\ZNF791
1 of 15
No
Yes
Hsap\ZNF792
1 of 15
No
No
Hsap\ZNF799
1 of 15
No
Yes
Hsap\ZNF805
1 of 15
No
No
Hsap\ZNF806
1 of 15
No
No
Hsap\ZNF813
1 of 15
No
No
Hsap\ZNF814
1 of 15
No
Yes
Hsap\ZNF816
1 of 15
No
No
Hsap\ZNF823
1 of 15
No
Yes
Hsap\ZNF829
1 of 15
No
No
Hsap\ZNF835
1 of 15
No
No
Hsap\ZNF840P
1 of 15
No
Yes
Hsap\ZNF845
1 of 15
No
No
Hsap\ZNF846
1 of 15
No
No
Hsap\ZNF852
1 of 15
No
No
Hsap\ZNF860
1 of 15
No
No
Hsap\ZNF875
1 of 15
No
Yes
Hsap\ZNF878
1 of 15
No
Yes
Hsap\ZNF879
1 of 15
No
No
Hsap\ZNF880
1 of 15
No
No
Hsap\ZNF888
1 of 15
No
No
Hsap\ZSCAN2
1 of 15
No
No
Hsap\ZSCAN12
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (225)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Mecom
10 of 15
Yes
Yes
Mmus\Prdm16
10 of 15
Yes
Yes
Mmus\AU041133
2 of 15
No
Yes
Mmus\Zfp26
2 of 15
No
Yes
Mmus\Zfp27
2 of 15
No
Yes
Mmus\Zfp62
2 of 15
No
Yes
Mmus\Zfp112
2 of 15
No
Yes
Mmus\Zfp442
2 of 15
No
Yes
Mmus\Zfp617
2 of 15
No
Yes
Mmus\Zfp619
2 of 15
No
Yes
Mmus\Zfp729a
2 of 15
No
Yes
Mmus\Zfp808
2 of 15
No
Yes
Mmus\2010315B03Rik
1 of 15
No
Yes
Mmus\2410141K09Rik
1 of 15
No
Yes
Mmus\2610008E11Rik
1 of 15
No
Yes
Mmus\4930522L14Rik
1 of 15
No
No
Mmus\AI987944
1 of 15
No
Yes
Mmus\AW146154
1 of 15
No
Yes
Mmus\BC024063
1 of 15
No
No
Mmus\Gli1
1 of 15
No
No
Mmus\Gm3604
1 of 15
No
No
Mmus\Gm5141
1 of 15
No
No
Mmus\Gm6710
1 of 15
No
No
Mmus\Gm10324
1 of 15
No
No
Mmus\Gm10778
1 of 15
No
Yes
Mmus\Gm11007
1 of 15
No
No
Mmus\Gm13212
1 of 15
No
No
Mmus\Gm14124
1 of 15
No
No
Mmus\Gm14139
1 of 15
No
No
Mmus\Gm14325
1 of 15
No
Yes
Mmus\Gm14391
1 of 15
No
Yes
Mmus\Gm32687
1 of 15
No
Yes
Mmus\Gm35315
1 of 15
No
Yes
Mmus\Gm45871
1 of 15
No
Yes
Mmus\Gm45951
1 of 15
No
Yes
Mmus\Klf10
1 of 15
No
No
Mmus\Klf11
1 of 15
No
No
Mmus\Mzf1
1 of 15
No
No
Mmus\Prdm9
1 of 15
No
Yes
Mmus\Rbak
1 of 15
No
Yes
Mmus\Rex2
1 of 15
No
No
Mmus\Rsl1
1 of 15
No
No
Mmus\Zfp2
1 of 15
No
No
Mmus\Zfp3
1 of 15
No
No
Mmus\Zfp7
1 of 15
No
No
Mmus\Zfp9
1 of 15
No
No
Mmus\Zfp11
1 of 15
No
No
Mmus\Zfp12
1 of 15
No
No
Mmus\Zfp14
1 of 15
No
No