GluRIII, DGluRIII, DGluRIIC, glutamate receptor III, GluRII-C
Please see the JBrowse view of Dmel\GluRIIC for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Antibody raised to C-terminal peptide -QGSGSSSGSNNAGRGEKEARV
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\GluRIIC using the Feature Mapper tool.
Embryonic expression of GluRIIC transcript is observed in the somatic musculature excluded from the CNS.
Comment: of all the muscles and from both type Ib and Is motoneurons.
GBrowse - Visual display of RNA-Seq signals
View Dmel\GluRIIC in GBrowse 22-1.5
2-1.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: GluRIII CG4226
Source for merge of: GluRIIC GluRIII
GluRIIC is required for synaptic localisation of GluRIIA and GluRIIB proteins. Either GluRIIA or GluRIIB, but not both, is required for synaptic localisation of GluRIIC protein. GluRIIA and GluRIIB proteins compete with each other for access to GluRIIC protein and subsequent localisation to the synapse.
GluRIIC is required for synaptic transmission at the neuromuscular junction.