• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG32147

General Information
Symbol	Dmel\CG32147	Species	D. melanogaster
Name		Annotation symbol	CG32147
Feature type	protein_coding_gene	FlyBase ID	FBgn0047178
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	71B5-71B5	Sequence location	3L:15,136,161..15,137,125 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG32147 (FBgn0047178). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: pyroglutamyl-peptidase activity. Based on sequence similarity, it is predicted to be involved in the biological process: proteolysis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase C15, pyroglutamyl peptidase I; Peptidase C15, pyroglutamyl peptidase I-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632593_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG32147. Gene sequence location is 3L:15136161..15137125.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN46263 BKN20639 HFA09346
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 71B5-71B5   Limits computationally determined from genome sequence between P{lacW}cp309s2172&P{lacW}l(3)j2A2j2A2 and P{EP}Tfb2EP572
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG32147 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG32147-RA FBtr0075647  NM_168616   879   224
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG32147-PA   FBpp0075400   24.8   224   6.39     NP_730035   AAN11795
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase C15, pyroglutamyl peptidase I (IPR000816) Peptidase C15, pyroglutamyl peptidase I-like (IPR016125)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAN11795   AY070984 AAL48606   BI167553   BI370768   BI373199   BP540937   BP541416   CO189195   CO266520   CO289940   CO293459   CZ484303   EC051437   EC051438   EC053935   EC054950   EC054965   EC055494   EC056364   EC056369   EC072924   EC219153   EC224247   GH748636   GH748955   GH749443   GH750990   GH752579   GH755188   GH758311   GH760136   GH760511   GH770911   GH773542   GH774344   GH774363   GH775820   GH778237   GH781258   GH782570   GH784021   GH785490   GH786551   GH788201   GH796911   GH798806   GH800818   GH802182   GH807552   GH808391   GH810658   GH811755   GH817923   GH818283   GH818355   GH827409   GH827459   GH828787   GH832180   GH836571   GH844047   GH846983   GH848946   GH851076   GH851152   GH852968   GH853546   GH856794   GH859351   GH860169   GH864985   GH865103   GH868117   GH868813   GH870746   GH871189   GH874903   GH877509   GH879387   GH884421   GH885413   GH886671   GH889944   GH891214   GH895227   GH897693   GH901811   GH903686   GH905339   GH907543   GH907691   GH909055   GH909225   GH909246   GH912522   GH914134   GH921234   GH925088   GH927687   GH928441   GH929778   GH931609   GH932853   GH933427
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SZB7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0047178    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0047178 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0047178 expression level Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1598) embryo 02-04hr  (2193) embryo 04-06hr  (1380) embryo 06-08hr  (1045) embryo 08-10hr  (1396) embryo 10-12hr  (1549) embryo 12-14hr  (1765) embryo 14-16hr  (708) embryo 16-18hr  (943) embryo 18-20hr  (1026) embryo 20-22hr  (1978) embryo 22-24hr  (2288) larva L1  (894) larva L2  (697) larva L3 12hr old  (778) larva L3 puffstage 1-2  (678) larva L3 puffstage 3-6  (654) larva L3 puffstage 7-9  (1358) white prepupae new  (2269) white prepupae 12hr  (657) white prepupae 24hr  (648) pupae 2d postWPP  (557) pupae 3d postWPP  (519) pupae 4d postWPP  (380) adult male 01day  (498) adult male 05day  (426) adult male 30day  (374) adult female 01day  (462) adult female 05day  (1003) adult female 30day  (1042) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1598) embryo 02-04hr  (2193) embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr  (1549) embryo 12-14hr  (1765) embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr  (1978) embryo 22-24hr  (2288) larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new  (2269) white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0047178 expression level Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1598) embryo 02-04hr  (2193) embryo 04-06hr  (1380) embryo 06-08hr  (1045) embryo 08-10hr  (1396) embryo 10-12hr  (1549) embryo 12-14hr  (1765) embryo 14-16hr  (708) embryo 16-18hr  (943) embryo 18-20hr  (1026) embryo 20-22hr  (1978) embryo 22-24hr  (2288) larva L1  (894) larva L2  (697) larva L3 12hr old  (778) larva L3 puffstage 1-2  (678) larva L3 puffstage 3-6  (654) larva L3 puffstage 7-9  (1358) white prepupae new  (2269) white prepupae 12hr  (657) white prepupae 24hr  (648) pupae 2d postWPP  (557) pupae 3d postWPP  (519) pupae 4d postWPP  (380) adult male 01day  (498) adult male 05day  (426) adult male 30day  (374) adult female 01day  (462) adult female 05day  (1003) adult female 30day  (1042) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1598 embryo 02-04hr  2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr  1549 embryo 12-14hr  1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr  1978 embryo 22-24hr  2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new  2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1598 embryo 02-04hr    2193 embryo 04-06hr    1380 embryo 06-08hr    1045 embryo 08-10hr    1396 embryo 10-12hr    1549 embryo 12-14hr    1765 embryo 14-16hr    708 embryo 16-18hr    943 embryo 18-20hr    1026 embryo 20-22hr    1978 embryo 22-24hr    2288 larva L1    894 larva L2    697 larva L3 12hr old    778 larva L3 puffstage 1-2    678 larva L3 puffstage 3-6    654 larva L3 puffstage 7-9    1358 white prepupae new    2269 white prepupae 12hr    657 white prepupae 24hr    648 pupae 2d postWPP    557 pupae 3d postWPP    519 pupae 4d postWPP    380 adult male 01day    498 adult male 05day    426 adult male 30day    374 adult female 01day    462 adult female 05day    1003 adult female 30day    1042 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0047178    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0047178 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0047178 expression level Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland    1390.7 Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules  (966.8) Adult Fat Body    117 Adult Salivary Gland  (1390.7) Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland  (1390.7) Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland    1390.7 Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0047178 expression level Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland    1390.7 Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules  (966.8) Adult Fat Body    117 Adult Salivary Gland  (1390.7) Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland  1390.7 Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    166.325 Larval Midgut    115.7 Larval Hindgut    323 Larval Malpighian Tubules    292.1 Larval Fat Body no informative data Larval Salivary Gland    206 Larval Trachea    293.05 Larval Carcass    173.2 Adult Head    117.4 Adult Eye    108.1 Adult Brain    114.7 Adult Thoracic-Abdominal Ganglion    193.1 Adult Crop    297.7 Adult Midgut    109.8 Adult Hindgut    308.4 Adult Malpighian Tubules    966.8 Adult Fat Body    117 Adult Salivary Gland    1390.7 Adult Heart    177.65 Adult VirginFemale Spermatheca    110.9 Adult InseminatedFemale Spermatheca    130 Adult Ovary    181.4 Adult Testis    19.4 Adult Male Accessory Gland    91.4 Adult Carcass    131.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    117.4   NA  Eye    108.1   NA  Brain    114.7   166.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    193.1   NA  Crop    297.7   115.7  Midgut    109.8   323  Hindgut    308.4   292.1  Malpighian Tubules    966.8   no informative data  Fat Body    117   206  Salivary Gland    1390.7   NA  Heart    177.65   293.05  Trachea    NA   NA  VirginFemale Spermatheca    110.9   NA  InseminatedFemale Spermatheca    130   NA  Ovary    181.4   NA  Testis    19.4   NA  Male Accessory Gland    91.4   173.2  Carcass    131.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0047178 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32147-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG32147GD10801 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG32147 Class Mutagen Stocks Known lesion CG32147EY05558 1 -- CG32147EY05589 1 -- CG32147f01821 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG32147 Class Mutagen Stocks Known lesion CG32147GD10801 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6262 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10801} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}CG32147f01821 NA insertion of mobile activating element P{EPgy2}CG32147EY05558 NA P{EPgy2}CG32147EY05589 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
pyroglutamyl-peptidase activity inferred from sequence or structural similarity with UniProtKB:Q9ESW8 (FlyBase Genome Annotators, 2004)
Biological Process
CV term Evidence References
proteolysis inferred from sequence or structural similarity with UniProtKB:Q9ESW8 (FlyBase Genome Annotators, 2004)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG32147 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0047178 DroID - A comprehensive database of gene and protein interactions. • FBgn0047178
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10738 Dere\GG13680 Dgri\GH17032 Dmoj\GI12237 Dper\GL25768 Dpse\GA16713 Dsec\GM24500 Dsim\GD12571 Dvir\GJ11468 Dwil\GK20489 Dyak\GE19976
Curated drosophilid orthologs	Dpse\GA16713
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002225-PA Aedes aegypti (mosquito) AGAP006964-PA Anopheles gambiae (mosquito) XP_001121977.1 Apis mellifera (honey bee) XP_001950411.1 Acyrthosiphon pisum (pea aphid) At1g56700.1 Arabidopsis thaliana (wall cress) 27120 Batrachochytrium dendrobatidis (chytrid fungus) 124319 Branchiostoma floridae (lancelet) XP_001893756.1 Brugia malayi (roundworm nematode) BGIBMGA012581-PA Bombyx mori (silk worm) ENSBTAP00000003320 Bos taurus (bovine) CN17316 Caenorhabditis brenneri (small nematode) CN21613 Caenorhabditis brenneri (small nematode) CBP29442 Caenorhabditis briggsae (nematode) CE37135 Caenorhabditis elegans (worm) ENSCAFP00000016014 Canis familiaris (dog) JA06022 Caenorhabditis japonica (nematode) JA18722 Caenorhabditis japonica (nematode) CPIJ003514 Culex pipens (mosquito) ENSCPOP00000015655 Cavia porcellus (guinea pig) RP39755 Caenorhabditis remanei (nematode) ENSCSAVP00000015906 Ciona savignyi (sedentary tunicate) 162094 Capitella spl (polychaete worm) DDB0189325 Dictyostelium discoideum (amoeba) 322333 Daphnia pulex (daphnia) ENSDARP00000071365 Danio rerio (zebra fish) ENSECAP00000009530 Equus caballus (horse) ENSGACP00000020459 Gymnopilus aculeatus (mushroom) ENSGALP00000011341 Gallus gallus (chicken) 75940 Hypsipyla robusta (cedar shoot borer) ENSP00000252813 Homo sapiens (human) ISCW015168-PA Ixodes scapularis (deer tick) 204313 Lottia gigantea (owl limpet) ENSMODP00000004226 Monodelphis domestica (gray opossum) ENSMMUP00000005884 Macaca mulatta (rhesus monkey) ENSMUSP00000070778 Mus musculus (house mouse) 212899 Nematostella vectensis (starlet anemone) XP_001603784.1 Nasonia vitripennis (wasp) ENSOANP00000015619 Ornithorynchus anatinus (platypus) ENSORLP00000010547 Oryzias latipes (japanese killifish) PHUM005008-PA Pediculus humanus (human body louse) PP06915 Pristionchus pacificus (nematode) ENSPPYP00000010910 Pongo pygmaeus (orangutan) ENSPTRP00000018263 Pan troglodytes (chimpanzee) ENSRNOP00000026597 Rattus norvegicus (norway rat) Smp_140810 Schistosoma mansoni (trematode parasite) XP_001186024.1 Strongylocentrotus purpuratus (purple sea urchin) 63763 Trichoplax adhaerens (metazoa) ENSTNIP00000014010 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000000289 Takifugu rubripes (pufferfish Takifugu) 3722.m00118 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000032029 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13640 NV14389 LH20936 ISCW015168 FBgn0237303 FBgn0222486 FBgn0198726 FBgn0184298 FBgn0179363 JGI_V11_322333 FBgn0076728 FBgn0163352 FBgn0134994 FBgn0124503 FBgn0105944 FBgn0087778 CPIJ003514 BGIBMGA012581 ACYPI002853 GB11230 AGAP006964 AAEL002225 PHUM140860 GLEAN_08878
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	15802 y1 w67c23; P{EPgy2}CG32147EY05558 15803 y1 w67c23; P{EPgy2}CG32147EY05589
VDRC	v34419 w1118; P{GD10801}v34419 v34418 w1118; P{GD10801}v34418/CyO
Genomic Clones ( 2 )
	BACR03G06 BACR18G16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 102 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE07960
Other clones	DPiM_RE07960
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE57508 RE60435
Other clones	33888 73611 CK01.93A.F11 EC051437 EC051438 EC053935 EC054950 EC054965 EC055494 EC056364 EC056369 EK043408 EK072624 EK146651 EK202948 FGA009B08 FGC001D08 RP003003840 RP003021167 RP003028118 RP003030749 RP003031014 RP003036480 RP003044211 RP003049173 RP003050756 RP003052981 RP003063532 RP003070641 RP003088632 RP003090724 RP003097989 RP003106891 RP003108725 RP003112899 RP003127272 RP003129389 RP003129611 RP003130900 RP003133248 RP003137352 RP003150448 RP003150567 RP003153372 RP003154445 RP003175400 RP003196498 RP003198846 RP003199930 RP003206393 RP003212398 RP003215630 RP003216829 RP003233903 RP003239510 RP003242560 RP003271142 RP003273058 RP003286934 RP003298411 RP003298814 RP003316158 RP003318252 RP003320615 RP003323019 RP003336406 RP003354438 RP003358210 RP003359273 RP003363433 RP003369903 RP003401975 RP003402729 RP003403342 RP003406886 RP003421595 RP003429690 RP003431605 RP003441843 RP003445283 RP003472422 RP003477414 RP003481393 RP003490615 RP003496003 RP003516682 RP003517958 RP003552968 RP003586367 RP003587429 RP003599622 RP003612105 RP003631092 RP003641423 RP003641968 RP003661585 RP003665504 RP003666320
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0047178 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 251690
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG32147) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_168616 RefSeq (Proteins) • NP_730035 DDBJ / EMBL / GenBank • AAL48606 AAN11795 AY070984 BI167553 CZ484303 Entrez Gene - A searchable database of RefSeq genes. • 251690 UniProtKB/TrEMBL • Q8SZB7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase C15, pyroglutamyl peptidase I (IPR000816) Peptidase C15, pyroglutamyl peptidase I-like (IPR016125)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0047178 DroID - A comprehensive database of gene and protein interactions. • FBgn0047178 DRSC - Results from RNAi screens. • FBgn0047178 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0047178 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG32147-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0047178 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 251690 InParanoid A subset of ortholog calls from InParanoid. • AAEL002225-PA Aedes aegypti (mosquito) AGAP006964-PA Anopheles gambiae (mosquito) XP_001121977.1 Apis mellifera (honey bee) XP_001950411.1 Acyrthosiphon pisum (pea aphid) At1g56700.1 Arabidopsis thaliana (wall cress) 27120 Batrachochytrium dendrobatidis (chytrid fungus) 124319 Branchiostoma floridae (lancelet) XP_001893756.1 Brugia malayi (roundworm nematode) BGIBMGA012581-PA Bombyx mori (silk worm) ENSBTAP00000003320 Bos taurus (bovine) CN17316 Caenorhabditis brenneri (small nematode) CN21613 Caenorhabditis brenneri (small nematode) CBP29442 Caenorhabditis briggsae (nematode) CE37135 Caenorhabditis elegans (worm) ENSCAFP00000016014 Canis familiaris (dog) JA06022 Caenorhabditis japonica (nematode) JA18722 Caenorhabditis japonica (nematode) CPIJ003514 Culex pipens (mosquito) ENSCPOP00000015655 Cavia porcellus (guinea pig) RP39755 Caenorhabditis remanei (nematode) ENSCSAVP00000015906 Ciona savignyi (sedentary tunicate) 162094 Capitella spl (polychaete worm) DDB0189325 Dictyostelium discoideum (amoeba) 322333 Daphnia pulex (daphnia) ENSDARP00000071365 Danio rerio (zebra fish) ENSECAP00000009530 Equus caballus (horse) ENSGACP00000020459 Gymnopilus aculeatus (mushroom) ENSGALP00000011341 Gallus gallus (chicken) 75940 Hypsipyla robusta (cedar shoot borer) ENSP00000252813 Homo sapiens (human) ISCW015168-PA Ixodes scapularis (deer tick) 204313 Lottia gigantea (owl limpet) ENSMODP00000004226 Monodelphis domestica (gray opossum) ENSMMUP00000005884 Macaca mulatta (rhesus monkey) ENSMUSP00000070778 Mus musculus (house mouse) 212899 Nematostella vectensis (starlet anemone) XP_001603784.1 Nasonia vitripennis (wasp) ENSOANP00000015619 Ornithorynchus anatinus (platypus) ENSORLP00000010547 Oryzias latipes (japanese killifish) PHUM005008-PA Pediculus humanus (human body louse) PP06915 Pristionchus pacificus (nematode) ENSPPYP00000010910 Pongo pygmaeus (orangutan) ENSPTRP00000018263 Pan troglodytes (chimpanzee) ENSRNOP00000026597 Rattus norvegicus (norway rat) Smp_140810 Schistosoma mansoni (trematode parasite) XP_001186024.1 Strongylocentrotus purpuratus (purple sea urchin) 63763 Trichoplax adhaerens (metazoa) ENSTNIP00000014010 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000000289 Takifugu rubripes (pufferfish Takifugu) 3722.m00118 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000032029 Xenopus tropicalis (frog) modMine - Data generated by the modENCODE project. • FBgn0047178 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13640 NV14389 LH20936 ISCW015168 FBgn0237303 FBgn0222486 FBgn0198726 FBgn0184298 FBgn0179363 JGI_V11_322333 FBgn0076728 FBgn0163352 FBgn0134994 FBgn0124503 FBgn0105944 FBgn0087778 CPIJ003514 BGIBMGA012581 ACYPI002853 GB11230 AGAP006964 AAEL002225 PHUM140860 GLEAN_08878
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:RE07960   CG32147 (Chen et al., 2008)
Name Synonym
Secondary FlyBase IDs
	FBgn0052147
References ( 13 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Chen et al., 2008, Genome Res. 18(1): 123--136 Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. [FBrf0202125]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Genome Annotators, 2004, Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. [FBrf0166453] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]