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Gene Dmel\Obp50a

General Information
Symbol	Dmel\Obp50a	Species	D. melanogaster
Name	Odorant-binding protein 50a	Annotation symbol	CG30067
Feature type	protein_coding_gene	FlyBase ID	FBgn0050067
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	50F6-50F6	Sequence location	2R:10,257,836..10,258,621 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Odorant-binding protein 50a is referred to in FlyBase by the symbol Dmel\Obp50a (CG30067, FBgn0050067). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: odorant binding. Based on sequence similarity, it is predicted to be involved in the biological process: sensory perception of chemical stimulus. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1624828_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Obp50a. Gene sequence location is 2R:10257836..10258621.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 50F6-50F6   Limits computationally determined from genome sequence between P{PZ}Tfb106949&P{PZ}l(2)0356303563 and P{lacW}l(2)k16805k16805
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Obp50a for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Obp50a-RA FBtr0087557  NM_166050   671   181 Obp50a-RB FBtr0087558  NM_206110   728   200
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Obp50a-PA   FBpp0086685   20.6   181   9.79     NP_725385   AAM71002 Obp50a-PB   FBpp0089300   22.7   200   10.27     NP_995832   AAS64854
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAM71002   AE013599 AAS64854   BT083461   EW713052
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A1Z9Q2 A1Z9Q1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    5.3 Larval Hindgut    5.8 Larval Malpighian Tubules    4.6 Larval Fat Body    6.8 Larval Salivary Gland    3.1 Larval Trachea    2.525 Larval Carcass    4.95 Adult Head    1.8 Adult Eye    1.45 Adult Brain    0.7 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    7.5 Adult Midgut    3.3 Adult Hindgut    4.8 Adult Malpighian Tubules    3.9 Adult Fat Body    6.3 Adult Salivary Gland    2.2 Adult Heart    2.025 Adult VirginFemale Spermatheca    3.8 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    2 Adult Testis    11.5 Adult Male Accessory Gland    5.6 Adult Carcass    14.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1.8   NA  Eye    1.45   NA  Brain    0.7   2.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3.7   NA  Crop    7.5   5.3  Midgut    3.3   5.8  Hindgut    4.8   4.6  Malpighian Tubules    3.9   6.8  Fat Body    6.3   3.1  Salivary Gland    2.2   NA  Heart    2.025   2.525  Trachea    NA   NA  VirginFemale Spermatheca    3.8   NA  InseminatedFemale Spermatheca    4.6   NA  Ovary    2   NA  Testis    no informative data   NA  Male Accessory Gland    5.6   4.95  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    0 adult male 01day    0 adult male 05day    0 adult male 30day    1 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050067 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30067-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Obp50a Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Obp50a Class Mutagen Stocks Known lesion Obp50aHMS00993 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Obp50aKK110383 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Obp50aGD6606 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6606} NA P{KK110383} NA P{TRiP.HMS00993} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
odorant binding inferred from sequence alignment with UniProtKB:P34174 (Hekmat-Scafe et al., 2002) inferred from sequence or structural similarity with lush (Vieira and Rozas, 2011)
Biological Process
CV term Evidence References
sensory perception of chemical stimulus inferred from sequence alignment with UniProtKB:P34174 (Hekmat-Scafe et al., 2002) inferred from sequence or structural similarity with lush (Vieira and Rozas, 2011)
Cellular Component
CV term Evidence References
extracellular region inferred from sequence model (Vieira and Rozas, 2011)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Obp50a allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (28) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6KWKD9 Dipteran inclusive ortholog search EOG6HX59B Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6KWKD9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Obp50a     Drosophila simulans   Dsim\Obp50a Y   Drosophila sechellia   Dsec\Obp50a Y   Drosophila erecta   Dere\Obp50a Y   Drosophila yakuba   Dyak\Obp50a Y   Drosophila ananassae   Dana\Obp50a Y   Drosophila pseudoobscura pseudoobscura   Dpse\Obp50a Y   Drosophila persimilis   Dper\Obp50a Y   Drosophila willistoni   Dwil\Obp50a Y   Drosophila virilis   Dvir\Obp50a Y   Drosophila mojavensis   Dmoj\Obp50a Y   Drosophila grimshawi   Dgri\Obp50a Y
Orthologs in non-Drosophila Dipterans (EOG6HX59B)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000124 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011483 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011481 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004729 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011490 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011484 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004730 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011497 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011489 Y Anopheles gambiae Malaria mosquito  Agam\OBP54 Y Anopheles gambiae Malaria mosquito  Agam\AGAP006075 Y Anopheles gambiae Malaria mosquito  Agam\OBP52 Y Anopheles gambiae Malaria mosquito  Agam\OBP50 Y Anopheles gambiae Malaria mosquito  Agam\OBP53 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008868 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008867 Y
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\Obp50a Drosophila sechellia Dsec\Obp50a Drosophila erecta Dere\Obp50a Drosophila yakuba Dyak\Obp50a Drosophila ananassae Dana\Obp50a Drosophila pseudoobscura pseudoobscura Dpse\Obp50a Drosophila persimilis Dper\Obp50a Drosophila willistoni Dwil\Obp50a Drosophila virilis Dvir\Obp50a Drosophila mojavensis Dmoj\Obp50a Drosophila grimshawi Dgri\Obp50a
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	34023 y1 sc* v1; P{TRiP.HMS00993}attP2
VDRC	v101974 P{KK110383}VIE-260B
Genomic Clones ( 1 )
	BACR16C17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 1 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP10514
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0050067 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246432
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG30067) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_166050 NM_206110 RefSeq (Proteins) • NP_725385 NP_995832 DDBJ / EMBL / GenBank • AAM71002 AAS64854 Entrez Gene - A searchable database of RefSeq genes. • 246432 UniProtKB/TrEMBL • A1Z9Q1 A1Z9Q2
Other Crossreferences
Linkouts
	DRSC - Results from RNAi screens. • FBgn0050067 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050067 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30067-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0050067 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246432 modMine - Data generated by the modENCODE project. • FBgn0050067
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-AE003814.2   CG30067 (Zhou et al., 2004, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) DmelObp50a (Vieira and Rozas, 2011) Obp50a (Kopp et al., 2008, Vieira et al., 2007, Zhou et al., 2009) unnamed (Robertson, 2000.4.6)
Name Synonym	Odorant-binding protein 50a (Hekmat-Scafe et al., 2002)
Secondary FlyBase IDs
	FBgn0043528
References ( 15 )
Research paper	Vieira and Rozas, 2011, Genome Biol. Evol. 3: 476--490 Comparative Genomics of the Odorant-Binding and Chemosensory Protein Gene Families across the Arthropoda: Origin and Evolutionary History of the Chemosensory System. [FBrf0214323] Zhou et al., 2009, PLoS Genet. 5(10): e1000681 Plasticity of the chemoreceptor repertoire in Drosophila melanogaster. [FBrf0209112] Kopp et al., 2008, Mol. Biol. Evol. 25(6): 1081--1092 Evolution of gene expression in the Drosophila olfactory system. [FBrf0205081] Vieira et al., 2007, Genome Biol. 8(11): R235 Comparative genomic analysis of the odorant-binding protein family in 12 Drosophila genomes: purifying selection and birth-and-death evolution. [FBrf0205523] Zhou et al., 2004, Gene 327(1): 117--129 'Plus-C' odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiae. [FBrf0174636] Hekmat-Scafe et al., 2002, Genome Res. 12(9): 1357--1369 Genome-wide analysis of the odorant-binding protein gene family in Drosophila melanogaster. [FBrf0151704]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Vieira and Rozas, 2011, Genome Biol. Evol. 3: Supplementary Data 1. OBP protein sequences in FASTA format. [FBrf0216366] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Hekmat-Scafe, 2002.3.5, OBP gene family. OBP gene family. [FBrf0151651] Robertson, 2000.4.6, FlyBase error report on Thu Apr 6 21:27:08 2000. FlyBase error report on Thu Apr 6 21:27:08 2000. [FBrf0128931]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]