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Gene Dmel\CG30185

General Information
Symbol	Dmel\CG30185	Species	D. melanogaster
Name		Annotation symbol	CG30185
Feature type	protein_coding_gene	FlyBase ID	FBgn0050185
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	CG5365
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	59E3-59E3	Sequence location	2R:19,431,564..19,432,422 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG30185 (FBgn0050185). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase/chloride channel, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval hindgut, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1630451_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG30185. Gene sequence location is 2R:19431564..19432422.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 59E3-59E3   Limits computationally determined from genome sequence between P{lacW}l(2)s4830s4830&P{lacW}chrwk06908 and P{PZ}Dcp-102132
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG30185 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG30185-RA FBtr0072060  NM_145193   720   179
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG30185-PA   FBpp0071969   20.0   179   7.05     NP_660194   AAM68253
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, C-terminal-like (IPR010987) Glutathione S-transferase/chloride channel, C-terminal (IPR017933) Glutathione S-transferase, C-terminal (IPR004046)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA695412   AE013599 AAM68253   AF171769   AY071743 AAL49365   AY113564 AAM29569   BF487959   BI573705   BI573706   BI617628   BI618065   CK657820   CL868515   CO264526   CO292613   CZ477675   EC052348   EC055223   EC083686   EC220833   EV585592   GH943232   GH945627   GH976030   GH976118
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MKK1 Q8MTU4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval hindgut, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    208.075 Larval Midgut    105.3 Larval Hindgut    118.2 Larval Malpighian Tubules    78.6 Larval Fat Body    57.4 Larval Salivary Gland    296.4 Larval Trachea    120.125 Larval Carcass    170.1 Adult Head    101.7 Adult Eye    120.325 Adult Brain    234.2 Adult Thoracic-Abdominal Ganglion    197.5 Adult Crop    74.9 Adult Midgut    177.2 Adult Hindgut    96.2 Adult Malpighian Tubules    33.7 Adult Fat Body    44 Adult Salivary Gland    175.1 Adult Heart    54.725 Adult VirginFemale Spermatheca    48.8 Adult InseminatedFemale Spermatheca    50.6 Adult Ovary    148.8 Adult Testis    48.1 Adult Male Accessory Gland    484 Adult Carcass    63.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    101.7   NA  Eye    120.325   NA  Brain    234.2   208.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    197.5   NA  Crop    74.9   105.3  Midgut    177.2   118.2  Hindgut    96.2   78.6  Malpighian Tubules    no informative data   57.4  Fat Body    44   296.4  Salivary Gland    175.1   NA  Heart    54.725   120.125  Trachea    NA   NA  VirginFemale Spermatheca    48.8   NA  InseminatedFemale Spermatheca    50.6   NA  Ovary    148.8   NA  Testis    48.1   NA  Male Accessory Gland    484   170.1  Carcass    63.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male    106 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (68) central nervous system, larvae L3  (67) central nervous system, pupae P8  (47) head, virgin 1-day female  (27) head, virgin 4-day female  26 head, virgin 20-day female  (32) head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female  (27) head, mated 1-day male  (41) head, mated 4-day male  (42) head, mated 20-day male  (49) salivary gland, larvae L3 wandering  (27) salivary gland, white prepupae  26 digestive system, larvae L3 wandering  (52) digestive system, 1-day adult  (43) digestive system, 4-day adult  (30) digestive system, 20-day adult  (37) fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8  (40) carcass, larvae L3 wandering  (46) carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female  (87) ovary, mated 4-day female  (59) testis, mated 4-day male  (57) accessory gland, mated 4-day male  (106) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male  106 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male    106 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male    106 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (68) central nervous system, larvae L3  (67) central nervous system, pupae P8  (47) head, virgin 1-day female  27 head, virgin 4-day female  26 head, virgin 20-day female  32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female  27 head, mated 1-day male  (41) head, mated 4-day male  (42) head, mated 20-day male  (49) salivary gland, larvae L3 wandering  27 salivary gland, white prepupae  26 digestive system, larvae L3 wandering  (52) digestive system, 1-day adult  (43) digestive system, 4-day adult  30 digestive system, 20-day adult  (37) fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8  (40) carcass, larvae L3 wandering  (46) carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female  (87) ovary, mated 4-day female  (59) testis, mated 4-day male  (57) accessory gland, mated 4-day male  (106) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male  106 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    68 central nervous system, larvae L3    67 central nervous system, pupae P8    47 head, virgin 1-day female    27 head, virgin 4-day female    26 head, virgin 20-day female    32 head, mated 1-day female    21 head, mated 4-day female    25 head, mated 20-day female    27 head, mated 1-day male    41 head, mated 4-day male    42 head, mated 20-day male    49 salivary gland, larvae L3 wandering    27 salivary gland, white prepupae    26 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    43 digestive system, 4-day adult    30 digestive system, 20-day adult    37 fat body, larvae L3 wandering    11 fat body, white prepupae    14 fat body, pupae P8    40 carcass, larvae L3 wandering    46 carcass, 1-day adult    15 carcass, 4-day adult    17 carcass, 20-day adult    17 ovary, virgin 4-day female    87 ovary, mated 4-day female    59 testis, mated 4-day male    57 accessory gland, mated 4-day male    106 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (60) embryo 02-04hr    15 embryo 04-06hr  (39) embryo 06-08hr  (36) embryo 08-10hr  (32) embryo 10-12hr  (35) embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr  26 embryo 18-20hr  (43) embryo 20-22hr  (58) embryo 22-24hr  (50) larva L1  (64) larva L2  (64) larva L3 12hr old  (52) larva L3 puffstage 1-2  (33) larva L3 puffstage 3-6  (34) larva L3 puffstage 7-9  (39) white prepupae new  (36) white prepupae 12hr  (52) white prepupae 24hr  (41) pupae 2d postWPP  (42) pupae 3d postWPP  (38) pupae 4d postWPP  (62) adult male 01day  (29) adult male 05day  (28) adult male 30day    25 adult female 01day  (48) adult female 05day  (59) adult female 30day  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (60) embryo 02-04hr    15 embryo 04-06hr  (39) embryo 06-08hr  (36) embryo 08-10hr  32 embryo 10-12hr  (35) embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr  26 embryo 18-20hr  (43) embryo 20-22hr  (58) embryo 22-24hr  (50) larva L1  (64) larva L2  (64) larva L3 12hr old  (52) larva L3 puffstage 1-2  (33) larva L3 puffstage 3-6  (34) larva L3 puffstage 7-9  (39) white prepupae new  (36) white prepupae 12hr  (52) white prepupae 24hr  (41) pupae 2d postWPP  (42) pupae 3d postWPP  (38) pupae 4d postWPP  (62) adult male 01day  29 adult male 05day  28 adult male 30day    25 adult female 01day  (48) adult female 05day  (59) adult female 30day  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    60 embryo 02-04hr    15 embryo 04-06hr    39 embryo 06-08hr    36 embryo 08-10hr    32 embryo 10-12hr    35 embryo 12-14hr    17 embryo 14-16hr    23 embryo 16-18hr    26 embryo 18-20hr    43 embryo 20-22hr    58 embryo 22-24hr    50 larva L1    64 larva L2    64 larva L3 12hr old    52 larva L3 puffstage 1-2    33 larva L3 puffstage 3-6    34 larva L3 puffstage 7-9    39 white prepupae new    36 white prepupae 12hr    52 white prepupae 24hr    41 pupae 2d postWPP    42 pupae 3d postWPP    38 pupae 4d postWPP    62 adult male 01day    29 adult male 05day    28 adult male 30day    25 adult female 01day    48 adult female 05day    59 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    147 embryonic 1182-4H    113 embryonic GM2    80 embryonic Kc167    74 embryonic S1    323 embryonic S3    140 leg disc CME L1    169 wing disc CME-W2    104 wing disc ML-DmD8    92 wing disc ML-DmD9    101 wing disc ML-DmD16-c3    139 wing disc ML-DmD21    230 wing disc ML-DmD32    125 haltere disc ML-DmD17-c3    195 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    127 CNS ML-DmBG1-c1    170 CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (147) embryonic 1182-4H  (113) embryonic GM2  (80) embryonic Kc167  (74) embryonic S1  (323) embryonic S3  (140) leg disc CME L1  (169) wing disc CME-W2  (104) wing disc ML-DmD8  (92) wing disc ML-DmD9  (101) wing disc ML-DmD16-c3  (139) wing disc ML-DmD21  (230) wing disc ML-DmD32  (125) haltere disc ML-DmD17-c3  (195) eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (127) CNS ML-DmBG1-c1  (170) CNS ML-DmBG2-c2  (84) tumorous blood cells mbn2  (64) ovary fGS/OSS  (48) ovary OSC  (59) ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (147) embryonic 1182-4H  (113) embryonic GM2    80 embryonic Kc167    74 embryonic S1  (323) embryonic S3  (140) leg disc CME L1  (169) wing disc CME-W2  104 wing disc ML-DmD8    92 wing disc ML-DmD9  101 wing disc ML-DmD16-c3  (139) wing disc ML-DmD21  (230) wing disc ML-DmD32  (125) haltere disc ML-DmD17-c3  (195) eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (127) CNS ML-DmBG1-c1  (170) CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    147 embryonic 1182-4H    113 embryonic GM2    80 embryonic Kc167    74 embryonic S1    323 embryonic S3    140 leg disc CME L1    169 wing disc CME-W2    104 wing disc ML-DmD8    92 wing disc ML-DmD9    101 wing disc ML-DmD16-c3    139 wing disc ML-DmD21    230 wing disc ML-DmD32    125 haltere disc ML-DmD17-c3    195 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    127 CNS ML-DmBG1-c1    170 CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    147 embryonic 1182-4H    113 embryonic GM2    80 embryonic Kc167    74 embryonic S1    323 embryonic S3    140 leg disc CME L1    169 wing disc CME-W2    104 wing disc ML-DmD8    92 wing disc ML-DmD9    101 wing disc ML-DmD16-c3    139 wing disc ML-DmD21    230 wing disc ML-DmD32    125 haltere disc ML-DmD17-c3    195 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    127 CNS ML-DmBG1-c1    170 CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (119) Schneider line 2 Sg4  (147) embryonic 1182-4H  (113) embryonic GM2  (80) embryonic Kc167  (74) embryonic S1  (323) embryonic S3  (140) leg disc CME L1  (169) wing disc CME-W2  (104) wing disc ML-DmD8  (92) wing disc ML-DmD9  (101) wing disc ML-DmD16-c3  (139) wing disc ML-DmD21  (230) wing disc ML-DmD32  (125) haltere disc ML-DmD17-c3  (195) eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  (127) CNS ML-DmBG1-c1  (170) CNS ML-DmBG2-c2  (84) tumorous blood cells mbn2  (64) ovary fGS/OSS  (48) ovary OSC  (59) ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  119 Schneider line 2 Sg4  (147) embryonic 1182-4H  113 embryonic GM2    80 embryonic Kc167    74 embryonic S1  (323) embryonic S3  140 leg disc CME L1  (169) wing disc CME-W2  104 wing disc ML-DmD8    92 wing disc ML-DmD9  101 wing disc ML-DmD16-c3  139 wing disc ML-DmD21  (230) wing disc ML-DmD32  125 haltere disc ML-DmD17-c3  (195) eye-antennal disc ML-DmD11  114 antennal disc ML-DmD20-c5  (185) mixed discs ML-DmD4-c1  127 CNS ML-DmBG1-c1  (170) CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    119 Schneider line 2 Sg4    147 embryonic 1182-4H    113 embryonic GM2    80 embryonic Kc167    74 embryonic S1    323 embryonic S3    140 leg disc CME L1    169 wing disc CME-W2    104 wing disc ML-DmD8    92 wing disc ML-DmD9    101 wing disc ML-DmD16-c3    139 wing disc ML-DmD21    230 wing disc ML-DmD32    125 haltere disc ML-DmD17-c3    195 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    185 mixed discs ML-DmD4-c1    127 CNS ML-DmBG1-c1    170 CNS ML-DmBG2-c2    84 tumorous blood cells mbn2    64 ovary fGS/OSS    48 ovary OSC    59 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (29) cold shock, 4-day adult    19 heat shock, 4-day adult  (33) Cadmium 50 mM 6 hrs, larvae L3  (64) Cadmium 50 mM 12 hrs, larvae L3  (51) Cadmium 50 mM 48 hrs, 4-day adult  (34) Cadmium 100 mM 48 hrs, 4-day adult  (50) Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3  (29) Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3  (46) Ethanol 5% 3 hrs, larvae L3  (54) Ethanol 10% 3 hrs, larvae L3  (43) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (49) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (48) Caffeine 25 mg/ml 48 hrs, 4-day adult  (30) Paraquat 5 mM 48 hrs, 4-day adult  (41) Paraquat 10 mM 48 hrs, 4-day adult  (45) Rotenone 2 μg 12 hrs, larvae L3  (68) Rotenone 8 μg 12 hrs, larvae L3  (78) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  29 cold shock, 4-day adult    19 heat shock, 4-day adult  (33) Cadmium 50 mM 6 hrs, larvae L3  (64) Cadmium 50 mM 12 hrs, larvae L3  (51) Cadmium 50 mM 48 hrs, 4-day adult  (34) Cadmium 100 mM 48 hrs, 4-day adult  (50) Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3  29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3  (46) Ethanol 5% 3 hrs, larvae L3  (54) Ethanol 10% 3 hrs, larvae L3  (43) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (49) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (48) Caffeine 25 mg/ml 48 hrs, 4-day adult  30 Paraquat 5 mM 48 hrs, 4-day adult  (41) Paraquat 10 mM 48 hrs, 4-day adult  (45) Rotenone 2 μg 12 hrs, larvae L3  (68) Rotenone 8 μg 12 hrs, larvae L3  (78) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    29 cold shock, 4-day adult    19 heat shock, 4-day adult    33 Cadmium 50 mM 6 hrs, larvae L3    64 Cadmium 50 mM 12 hrs, larvae L3    51 Cadmium 50 mM 48 hrs, 4-day adult    34 Cadmium 100 mM 48 hrs, 4-day adult    50 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    15 Zinc 5 mM 12 hrs, larvae L3    29 Zinc 4.5 mM 48 hrs, 4-day adult    21 Ethanol 2.5% 3 hrs, larvae L3    46 Ethanol 5% 3 hrs, larvae L3    54 Ethanol 10% 3 hrs, larvae L3    43 Caffeine 1.5 mg/ml 4 hrs, larvae L3    49 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    48 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    41 Paraquat 10 mM 48 hrs, 4-day adult    45 Rotenone 2 μg 12 hrs, larvae L3    68 Rotenone 8 μg 12 hrs, larvae L3    78 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_26 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • RH48588 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050185 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30185-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG30185d11316 CG30185EY11794 CG30185EY16074 Sterility Allele fertile CG30185d11316 CG30185EY11794 CG30185EY16074 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG30185 Class Mutagen Stocks Known lesion CG30185d11316 P-element activity 2 -- CG30185CB-6776-3 1 -- CG30185EY11794 P-element activity 0 -- CG30185EY16074 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG30185 Class Mutagen Stocks Known lesion CG30185KK107934 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG30185GD11122 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes CG30185NIG.30185R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7179 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11122} NA P{KK107934} NA P{NIG.30185R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG30185EY11794 NA P{EPgy2}CG30185EY16074 NA P{XP}CG30185d11316 NA miscellaneous insertions P{RS3}CG30185CB-6776-3 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG30185 - Aats-lys anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG30185 - Arpc3A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG30185 - CG10641 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG30185 - CG1129 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG30185 - CG15100 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) CG30185 - CG7049 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG30185 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG30185 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0050185 DroID - A comprehensive database of gene and protein interactions. • FBgn0050185 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246507
Orthologs
OrthoDB Orthologs (30) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6F4SXK Dipteran inclusive ortholog search EOG6JM7ZZ Insect inclusive ortholog search EOG6K6F1Z Arthropod inclusive ortholog search EOG6X3FJ3 Metazoa inclusive ortholog search EOG6Z99R9
Orthologs in Drosophila Species (EOG6F4SXK)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG30185     Drosophila simulans   Dsim\GD11773 Y   Drosophila sechellia   Dsec\GM16023 Y   Drosophila erecta   Dere\GG22864 Y   Drosophila yakuba   Dyak\GE14300 Y   Drosophila ananassae   Dana\GF13062 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15709 Y   Drosophila persimilis   Dper\GL16868 Y   Drosophila willistoni   Dwil\GK23190 Y   Drosophila virilis   Dvir\GJ15092 Y   Drosophila mojavensis   Dmoj\GI19925 Y   Drosophila grimshawi   Dgri\GH21448 Y
Orthologs in non-Drosophila Dipterans (EOG6JM7ZZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007366   Anopheles gambiae Malaria mosquito  Agam\AGAP004929   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017532
Orthologs in non-Dipteran Insects (EOG6K6F1Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC100577000   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003033   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13804   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14369   Linepithema humile Argentine ant  Lhum\LH12577   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12150   Pediculus humanus Human body louse  Phum\PHUM062680
Orthologs in non-Insect Arthropods (EOG6X3FJ3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW004346
Orthologs in non-Arthropod Metazoa (EOG6Z99R9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016439gn   Danio rerio Zebrafish  Drer\wu:fe14c11   Xenopus tropicalis Western clawed frog  Xtro\eef1e1   Gallus gallus Domestic chicken  Ggal\EEF1E1   Mus musculus House mouse  Mmus\Eef1e1   Rattus norvegicus Norway rat  Rnor\Eef1e1   Homo sapiens Human  Hsap\EEF1E1
Human Orthologs (1)
Gene OMIM HGNC Hsap\EEF1E1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11773 Drosophila sechellia Dsec\GM16023 Drosophila erecta Dere\GG22864 Drosophila yakuba Dyak\GE14300 Drosophila ananassae Dana\GF13062 Drosophila pseudoobscura pseudoobscura Dpse\GA15709 Drosophila persimilis Dper\GL16868 Drosophila willistoni Dwil\GK23190 Drosophila virilis Dvir\GJ15092 Drosophila mojavensis Dmoj\GI19925 Drosophila grimshawi Dgri\GH21448
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	19348 w1118; P{XP}CG30185d11316
Harvard	- P{XP}CG30185d11316
Kyoto	124217 w1118; P{RS3}CG30185CB-6776-3
VDRC	v104364 P{KK107934}VIE-260B
Genomic Clones ( 2 )
	BACR25I01 BACR48M01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 19 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH09246 RH48588
Other clones	AF171769 DPiM_RH48588
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT23088 GM02775 LP24410 RH48023
Other clones	10977 21413 Dmel_dig_004715_0638_0352 EC052348 EC055223 EK139458 EK200602 RP004228360 RP004253313 RP004327056 RP004328998
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0050185 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246507
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG30185 anon-EST:Posey25 (Ashburner, 2004.6.30)
Additional comments	Annotation CG5365 split into CG33150 (Gr59f) and CG30185 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_145193 RefSeq (Proteins) • NP_660194 DDBJ / EMBL / GenBank • AAL49365 AAM29569 AAM68253 AF171769 AY071743 AY113564 BI573705 BI573706 BI618065 CL868515 CZ477675 Entrez Gene - A searchable database of RefSeq genes. • 246507 UniProtKB/TrEMBL • Q8MKK1 Q8MTU4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glutathione S-transferase, C-terminal-like (IPR010987) Glutathione S-transferase/chloride channel, C-terminal (IPR017933) Glutathione S-transferase, C-terminal (IPR004046) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH48588
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0050185 DroID - A comprehensive database of gene and protein interactions. • FBgn0050185 DRSC - Results from RNAi screens. • FBgn0050185 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050185 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30185-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0050185 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246507 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246507 modMine - Data generated by the modENCODE project. • FBgn0050185
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	anon-EST:Posey25   CG5365 (Dunipace et al., 2001, BDGP Project Members, 2000-, ) CG30185 (Dworkin and Gibson., 2006, Keleman et al., 2009.8.5, Hughes et al., 2008, Fisher et al., 2008, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
	FBgn0027712 FBgn0034875
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 3 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Website  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...