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Gene Dmel\CG30345

General Information
Symbol	Dmel\CG30345	Species	D. melanogaster
Name		Annotation symbol	CG30345
Feature type	protein_coding_gene	FlyBase ID	FBgn0050345
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	45A13-45A13	Sequence location	2R:5,036,194..5,039,397 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG30345 (FBgn0050345). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain, general substrate transporter; Sugar transporter, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1627500_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG30345. Gene sequence location is 2R:5036194..5039397.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 45A13-45A13   Limits computationally determined from genome sequence between P{lacW}CG8788k04512&P{lacW}l(2)k13412k13412 and P{PZ}Pkn06736
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG30345 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG30345-RB FBtr0305317  NM_165656   2217   496
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG30345-PB   FBpp0293860   54.9   496   6.09     NP_724760   AAM68814
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sugar transporter, conserved site (IPR005829) Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAM68814   AI133843   BI623871   BT025924   CO181809   CO314045   EC225773   EL882407   EL882653   GO271061   GO271137
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A1Z7R4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval midgut, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.525 Larval Midgut    218.7 Larval Hindgut    94.7 Larval Malpighian Tubules    54.9 Larval Fat Body    97.9 Larval Salivary Gland    24.5 Larval Trachea    9.75 Larval Carcass    27.925 Adult Head    36.9 Adult Eye    31.85 Adult Brain    14.2 Adult Thoracic-Abdominal Ganglion    11.7 Adult Crop    15.9 Adult Midgut    79.9 Adult Hindgut    83.5 Adult Malpighian Tubules    20 Adult Fat Body    35.4 Adult Salivary Gland    22.3 Adult Heart    39.475 Adult VirginFemale Spermatheca    32 Adult InseminatedFemale Spermatheca    27.9 Adult Ovary    10.4 Adult Testis    11.1 Adult Male Accessory Gland    118 Adult Carcass    63.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    36.9   NA  Eye    31.85   NA  Brain    no informative data   3.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   218.7  Midgut    79.9   94.7  Hindgut    83.5   54.9  Malpighian Tubules    no informative data   97.9  Fat Body    35.4   24.5  Salivary Gland    no informative data   NA  Heart    39.475   9.75  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    no informative data   NA  Testis    no informative data   NA  Male Accessory Gland    118   27.925  Carcass    63.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (52) digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (52) digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    3 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    52 digestive system, 1-day adult    6 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    3 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    2 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during late larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9  (39) white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9  (39) white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    3 embryo 18-20hr    4 embryo 20-22hr    5 embryo 22-24hr    5 larva L1    3 larva L2    3 larva L3 12hr old    4 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    39 white prepupae new    18 white prepupae 12hr    4 white prepupae 24hr    1 pupae 2d postWPP    1 pupae 3d postWPP    3 pupae 4d postWPP    7 adult male 01day    14 adult male 05day    10 adult male 30day    9 adult female 01day    10 adult female 05day    5 adult female 30day    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    7 embryonic Kc167    3 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    1 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    2 ovary fGS/OSS    1 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    4 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    6 Cadmium 50 mM 12 hrs, larvae L3    11 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    3 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    12 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050345 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30345-RA;U89994
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG30345d04911 viable, with Scer\GAL4pnr-MD237 CG30345GD1891 Sterility Allele fertile CG30345d04911 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG30345 Class Mutagen Stocks Known lesion CG30345d04911 P-element activity 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG30345 Class Mutagen Stocks Known lesion CG30345GD1891 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG30345HMS00957 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG30345KK107768 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1891} NA P{KK107768} NA P{TRiP.HMS00957} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}CG30345d04911 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
transporter activity inferred from electronic annotation with InterPro:IPR005829 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR011701 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG30345 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0050345 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246553
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61C7FX Dipteran inclusive ortholog search EOG6NGGW2 Insect inclusive ortholog search EOG6PRRMJ Arthropod inclusive ortholog search EOG6V41QG Metazoa inclusive ortholog search EOG6F554R
Orthologs in Drosophila Species (EOG61C7FX)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG30345     Drosophila simulans   Dsim\GD10640     Drosophila sechellia   Dsec\GM21105     Drosophila erecta   Dere\GG23423     Drosophila yakuba   Dyak\GE19262     Drosophila ananassae   Dana\GF11963     Drosophila pseudoobscura pseudoobscura   Dpse\GA15776     Drosophila persimilis   Dper\GL17011
Orthologs in non-Drosophila Dipterans (EOG6NGGW2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001699 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001691 Y Anopheles gambiae Malaria mosquito  Agam\AGAP005317 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015155 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015153 Y
Orthologs in non-Dipteran Insects (EOG6PRRMJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB49339 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000129 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000127 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12465 Y Atta cephalotes Leafcutter ant  Acep\ACEP14460 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO16643 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15355 Y Linepithema humile Argentine ant  Lhum\LH20309 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16999 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB23265 Y Solenopsis invicta Red fire ant  Sinv\SINV16683 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI002425 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI080681 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI072777 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI23467 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI50787 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014434 Y Bombyx mori Silkmoth  Bmor\BGIBMGA004081 Y Pediculus humanus Human body louse  Phum\PHUM424170 Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG6F554R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025146gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018750gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012775gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008807gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008808gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	19209 w1118; P{XP}CG30345d04911 33994 y1 sc* v1; P{TRiP.HMS00957}attP2
Harvard	- P{XP}CG30345d04911
VDRC	v103652 P{KK107768}VIE-260B v42868 w1118; P{GD1891}v42868 v42867 w1118; P{GD1891}v42867/CyO
Genomic Clones ( 1 )
	BACR10M14 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 9 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP12271
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH10572 RH56228
Other clones	108504 DMG7-chr2R.9.004.pred.a EC15022 EK234761 IP12171 IP12371
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0050345 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246553
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG30345) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165656 RefSeq (Proteins) • NP_724760 DDBJ / EMBL / GenBank • AAM68814 Entrez Gene - A searchable database of RefSeq genes. • 246553 UniProtKB/TrEMBL • A1Z7R4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sugar transporter, conserved site (IPR005829) Major facilitator superfamily (IPR011701) Major facilitator superfamily domain, general substrate transporter (IPR016196)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0050345 DRSC - Results from RNAi screens. • FBgn0050345 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050345 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30345-RA;U89994 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0050345 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246553 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246553 modMine - Data generated by the modENCODE project. • FBgn0050345
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG30345 (Keleman et al., 2009.8.5, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
References ( 9 )
Research paper	Bartolome and Maside, 2004, Genet. Res. (Camb.) 83(2): 91--100 The lack of recombination drives the fixation of transposable elements on the fourth chromosome of Drosophila melanogaster. [FBrf0179127]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]