FlyBase Gene Report: Dmel\Ugt50B3

General Information

Symbol

Dmel\Ugt50B3

Species

D. melanogaster

Name

UDP-glycosyltransferase family 50 member B3

Annotation Symbol

CG30438

Feature Type

protein_coding_gene

FlyBase ID

FBgn0050438

Gene Model Status

Current

Stock Availability

10 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

BcDNA:LD09936

Key Links

Genomic Location

Cytogenetic map

41F2-41F3

Sequence location

2R:5,496,674..5,549,543 [+]

Recombination map

2-55

RefSeq locus

NT_033778 REGION:5496674..5549543

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (3 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables UDP-glycosyltransferase activity

inferred from sequence model

(Ahn and Marygold, 2021)

inferred from electronic annotation with InterPro:IPR002213

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN005360456

(GO Reference Genome Project, 2011-)

Biological Process (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in glycosylation

inferred from sequence model

(Ahn and Marygold, 2021)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in endoplasmic reticulum membrane

inferred from sequence model

(Ahn and Marygold, 2021)

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES -: The GT1 family of UDP-glycosyltransferases (UGTs) catalyze the transfer the glycosyl group from a nucleotide sugar, such as UDP-glucuronic acid, UDP-galactose, UDP-glucose or UDP-xylose, to a variety of small hydrophobic acceptor molecules (aglycones), resulting in more hydrophilic compounds that are efficiently excreted. Mammalian/vertebrate UGTs mainly use UDP-glucuronic acid as the sugar donor, whereas invertebrates and plants appear to use UDP-glucose as the main donor. Insect UGTs play a major role in the detoxification of substrates, cuticle formation, pigmentation and olfaction. The GT1 family is defined by a common protein structure and signature sequence of 44 amino acids responsible for binding the UDP moiety of the sugar donor. (Adapted from FBrf0152079 and PMID:26453144).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Ugt50B3 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q8SYL7)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.41

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Ugt50B3-RA

FBtr0086067

NM_165435

1993

435

Ugt50B3-RB

FBtr0086068

NM_165436

2426

524

Ugt50B3-RC

FBtr0086069

NM_165437

2732

524

Ugt50B3-RD

FBtr0086070

NM_165438

2310

524

Ugt50B3-RE

FBtr0335263

NM_001273781

2226

524

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Ugt50B3-PA

FBpp0085403

49.9

435

9.59

FBpp0085404

59.7

524

9.48

FBpp0085405

59.7

524

9.48

FBpp0085406

59.7

524

9.48

FBpp0307246

59.7

524

9.48

Q8SYL7

NP_001260710

AGB93245

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

524 aa isoforms: Ugt50B3-PB, Ugt50B3-PC, Ugt50B3-PD, Ugt50B3-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ugt50B3 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.10

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

plasmatocyte primordium

Comment: reported as plasmatocytes anlage

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic head epidermis

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

embryonic/larval plasmatocyte

(Fisher et al., 2012)

embryonic stage 15

tracheal fusion cell

(Chandran et al., 2014)

embryonic/larval tracheal dorsal trunk

(Chandran et al., 2014)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Ugt50B3 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Ugt50B3

View exonic expression by tissue for Dmel\Ugt50B3

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0050438

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

246614/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0050438

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0050438

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0050438

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG30438

Flygut - An atlas of the Drosophila adult midgut

FBgn0050438

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Ugt50B3

Stages(s) 1-3
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 9 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ugt50B3

Transgenic constructs containing regulatory region of Ugt50B3

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 3 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Ugt50B3^GD1636

viable, with Scer\GAL4^Act5C.PU

Ugt50B3^RNAi.UAS.cYa

viable, with Scer\GAL4^Mef2.PR

Ugt50B3^GD1636

viable, with Scer\GAL4^pnr-MD237

Ugt50B3^GD1636

viable, with Scer\GAL4^tin.CΔ4

Ugt50B3^GD1636

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (22)

Hsap\UGT8

8 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

5 of 14

5 of 14

5 of 14

5 of 14

Yes

Hsap\UGT3A2

5 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (18)

Rnor\Ugt8

8 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

4 of 14

Mus musculus (laboratory mouse) (22)

Mmus\Ugt8a

7 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

5 of 14

Yes

Mmus\Ugt3a2

5 of 14

Yes

Mmus\Ugt1a10

1 of 14

Xenopus tropicalis (Western clawed frog) (6)

Xtro\ugt1a1

5 of 13

Yes

Xtro\ugt1a6

5 of 13

Yes

Xtro\ugt8

5 of 13

Yes

Xtro\capsl

3 of 13

Xtro\ugt2a1

3 of 13

Xtro\LOC100488176

1 of 13

Danio rerio (Zebrafish) (24)

Drer\ugt8

6 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

4 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (71)

Cele\ugt-15

8 of 14

Yes

Cele\ugt-16

8 of 14

Yes

Cele\ugt-17

8 of 14

Yes

Cele\ugt-18

8 of 14

Yes

Cele\ugt-19

8 of 14

Yes

Cele\ugt-20

8 of 14

Yes

Cele\ugt-22

8 of 14

Yes

Cele\ugt-23

8 of 14

Yes

Cele\ugt-24

8 of 14

Yes

Cele\ugt-26

8 of 14

Yes

Cele\ugt-44

8 of 14

Yes

Cele\ugt-21

7 of 14

Yes

Cele\ugt-25

7 of 14

Yes

7 of 14

7 of 14

7 of 14

7 of 14

7 of 14

Yes

Cele\ugt-32

7 of 14

Cele\ugt-33

7 of 14

Cele\ugt-34

7 of 14

Yes

Cele\ugt-38

7 of 14

Yes

Cele\ugt-39

7 of 14

Yes

Cele\ugt-43

7 of 14

Yes

Cele\ugt-45

7 of 14

Yes

Cele\ugt-58

7 of 14

Yes

Cele\ugt-66

7 of 14

Cele\H23N18.4

6 of 14

Yes

Cele\ugt-1

6 of 14

Yes

Cele\ugt-2

6 of 14

Yes

Cele\ugt-4

6 of 14

Yes

Cele\ugt-5

6 of 14

Yes

Cele\ugt-6

6 of 14

Yes

Cele\ugt-7

6 of 14

Yes

Cele\ugt-8

6 of 14

Yes

Cele\ugt-9

6 of 14

Yes

Cele\ugt-10

6 of 14

Yes

Cele\ugt-11

6 of 14

Yes

Cele\ugt-12

6 of 14

Yes

Cele\ugt-13

6 of 14

Yes

Cele\ugt-14

6 of 14

Yes

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

6 of 14

Yes

Cele\ugt-59

6 of 14

Yes

Cele\C03A7.13

5 of 14

Yes

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

5 of 14

Yes

Cele\ugt-52

5 of 14

Yes

Cele\ugt-56

5 of 14

Yes

Cele\ugt-61

5 of 14

Cele\ugt-62

5 of 14

Cele\ugt-54

4 of 14

Yes

4 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

Anopheles gambiae (African malaria mosquito) (24)

Agam\AgaP_AGAP002449

12 of 12

Yes

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

4 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

3 of 12

Arabidopsis thaliana (thale-cress) (113)

Atha\AT1G50580

2 of 13

Yes

Atha\AT1G64910

2 of 13

Yes

Atha\AT1G64920

2 of 13

Yes

Atha\AT2G22590

2 of 13

Yes

Atha\AT2G22930

2 of 13

Yes

Atha\AT2G28080

2 of 13

Yes

Atha\AT3G02100

2 of 13

Yes

Atha\AT3G22250

2 of 13

Yes

Atha\AT3G29630

2 of 13

Yes

Atha\AT3G46650

2 of 13

Yes

Atha\AT3G46680

2 of 13

Yes

Atha\AT3G46690

2 of 13

Yes

Atha\AT3G46700

2 of 13

Yes

Atha\AT3G46720

2 of 13

Yes

Atha\AT4G09500

2 of 13

Yes

Atha\AT4G27560

2 of 13

Yes

Atha\AT4G27570

2 of 13

Yes

Atha\AT5G05880

2 of 13

Yes

Atha\AT5G05890

2 of 13

Yes

Atha\AT5G05900

2 of 13

Yes

Atha\AT5G17040

2 of 13

Yes

Atha\AT5G37950

2 of 13

Yes

Atha\AT5G38010

2 of 13

Yes

Atha\AT5G38040

2 of 13

Yes

Atha\AT5G49690

2 of 13

Yes

Atha\AT5G53990

2 of 13

Yes

Atha\AT5G54010

2 of 13

Yes

Atha\AT5G65550

2 of 13

Yes

Atha\UF3GT

2 of 13

Yes

Atha\UGT71B6

2 of 13

Yes

Atha\UGT71C5

2 of 13

Yes

Atha\UGT71D1

2 of 13

Yes

Atha\UGT73B3

2 of 13

Yes

Atha\UGT73B4

2 of 13

Yes

Atha\UGT73B5

2 of 13

Yes

Atha\UGT75B1

2 of 13

Yes

Atha\UGT76B1

2 of 13

Yes

Atha\UGT76C1

2 of 13

Yes

Atha\UGT76C2

2 of 13

Yes

Atha\UGT76D1

2 of 13

Yes

Atha\UGT76E1

2 of 13

Yes

Atha\UGT76E2

2 of 13

Yes

Atha\UGT76E11

2 of 13

Yes

Atha\UGT76E12

2 of 13

Yes

Atha\UGT78D1

2 of 13

Yes

Atha\UGT78D2

2 of 13

Yes

Atha\UGT78D3

2 of 13

Yes

Atha\UGT85A1

2 of 13

Yes

Atha\UGT85A2

2 of 13

Yes

Atha\UGT85A3

2 of 13

Yes

Atha\UGT85A4

2 of 13

Yes

Atha\UGT85A5

2 of 13

Yes

Atha\UGT85A7

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Ugt50B3. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (34)

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

9 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

8 of 13

7 of 13

7 of 13

7 of 13

6 of 13

6 of 13

6 of 13

6 of 13

6 of 13

5 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

UGT8; UDP glycosyltransferase 8

8 of 14

601291

UGT1A1; UDP glucuronosyltransferase family 1 member A1

6 of 14

191740

UGT1A4; UDP glucuronosyltransferase family 1 member A4

6 of 14

606429

UGT1A6; UDP glucuronosyltransferase family 1 member A6

6 of 14

606431

UGT1A7; UDP glucuronosyltransferase family 1 member A7

6 of 14

606432

UGT1A8; UDP glucuronosyltransferase family 1 member A8

6 of 14

606433

UGT1A9; UDP glucuronosyltransferase family 1 member A9

6 of 14

606434

UGT1A10; UDP glucuronosyltransferase family 1 member A10

6 of 14

606435

UGT2A1; UDP glucuronosyltransferase family 2 member A1 complex locus

6 of 14

604716

UGT2A3; UDP glucuronosyltransferase family 2 member A3

6 of 14

616382

UGT2B4; UDP glucuronosyltransferase family 2 member B4

6 of 14

600067

UGT2B7; UDP glucuronosyltransferase family 2 member B7

6 of 14

600068

UGT2B10; UDP glucuronosyltransferase family 2 member B10

6 of 14

600070

UGT2B11; UDP glucuronosyltransferase family 2 member B11

6 of 14

603064

UGT2B15; UDP glucuronosyltransferase family 2 member B15

6 of 14

600069

UGT2B17; UDP glucuronosyltransferase family 2 member B17

6 of 14

601903

BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 12; BMND12

UGT2B28; UDP glucuronosyltransferase family 2 member B28

6 of 14

606497

UGT1A3; UDP glucuronosyltransferase family 1 member A3

5 of 14

606428

UGT1A5; UDP glucuronosyltransferase family 1 member A5

5 of 14

606430

UGT2A2; UDP glucuronosyltransferase family 2 member A2

5 of 14

619809

UGT3A1; UDP glycosyltransferase family 3 member A1

5 of 14

616383

UGT3A2; UDP glycosyltransferase family 3 member A2

5 of 14

616384

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0050438

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-55

Cytogenetic map

41F2-41F3

Sequence location

2R:5,496,674..5,549,543 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

41F2-41F3

Limits computationally determined from genome sequence between P{PZ}vlc⁰⁷⁰²²&P{lacW}l(2)09851^k08138 and P{PZ}l(2)09851⁰⁹⁸⁵¹&P{lacW}Src42A^k10108

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-55

(FlyBase, 2016)

2-55.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

43118

y¹ w^*; Mi{MIC}Ugt50B3^MI07302

38163

y¹ w^*; Mi{MIC}Ugt50B3^MI04756/SM6a

14022

y¹ w^67c23; P{SUPor-P}Ugt50B3^KG06088

51790

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03346}attP2

61793

y¹ w^67c23; Mi{PT-GFSTF.1}Ugt50B3^{MI07302-GFSTF.1}

81173

y¹ w^*; TI{CRIMIC.TG4.0}Ugt50B3^{CR01103-TG4.0}/SM6a

NIG-Fly

30438R-1

P{NIG.30438R}1

HMC03346

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03346}attP2

VDRC

v107604

P{KK106436}VIE-260B

v37104

w¹¹¹⁸; P{GD1636}v37104

Genomic Clones (39)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (13)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0050438

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0050438

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

New annotation (CG30438) in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG30438 BcDNA:RE54684

(FlyBase, 1996-)

Source for merge of: CG30438 BcDNA:LD09936

(FlyBase, 1996-)

Additional comments

Source for merge of CG30438 BcDNA:RE54684 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Source for merge of CG30438 BcDNA:LD09936 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Ugt50B3 CG30438

(Bock et al., 2018)

Nomenclature comments

UGT gene nomenclature follows that of the UGT Nomenclature Committee and, despite the superficial resemblance in some cases, does not indicate the cytological location of the gene. Rather, the first number specifies a UGT family, the letter then specifies a subfamily, and the final number specifies an individual member.

(Bock et al., 2018)

Etymology

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

BcDNA:LD09936

(Ranz et al., 2003)

BcDNA:RE54684

CG30438

(Pang et al., 2021, Ou et al., 2016, Coelho et al., 2015, Gene Disruption Project members, 2015-, Yamamoto-Hino et al., 2015, Chandran et al., 2014, Toshima et al., 2014, Ahn et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Di Stefano et al., 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Emerson et al., 2008, Turner et al., 2008, Yasuhara and Wakimoto, 2008, Rossi et al., 2007)

UGT50B3

(Ahn et al., 2012)

Ugt50B3

(Ahn and Marygold, 2021, Bock et al., 2018, Gene Disruption Project members, 2018-)

Name Synonyms

UDP-glycosyltransferase family 50 member B3

Secondary FlyBase IDs

FBgn0047093
FBgn0047220

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 51 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

246614

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q8SYL7

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q8SYL7

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0050438

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

246614/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0050438

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0050438

FlyMine - An integrated database for Drosophila genomics

FBgn0050438

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG30438

MARRVEL_MODEL - MARRVEL (model organism gene)

246614

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0050438

DroID - A comprehensive database of gene and protein interactions.

FBgn0050438

DRSC - Results frm RNAi screens

FBgn0050438

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0050438

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0050438

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG30438

Flygut - An atlas of the Drosophila adult midgut

FBgn0050438

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC032845

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (51)

The following external sites may use different assemblies or annotations than FlyBase.

-0.10

Report Sections