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Gene Dmel\CG30503

General Information
Symbol	Dmel\CG30503	Species	D. melanogaster
Name		Annotation symbol	CG30503
Feature type	protein_coding_gene	FlyBase ID	FBgn0050503
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	43C1-43C1	Sequence location	2R:3,331,329..3,333,297 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG30503 (FBgn0050503). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: calcium ion binding; phospholipase A2 activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid catabolic process; phospholipid metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Phospholipase A2; Phospholipase A2 domain; Phospholipase A2, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult heart, adult fat body, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval fat body, larval salivary gland, adult spermathecae, adult male accessory gland. Gene sequence location is 2R:3331329..3333297.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 43C1-43C1   Limits computationally determined from genome sequence between P{lacW}cosk16101 and P{EP}CG1600EP398
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG30503 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG30503-RA FBtr0089003  NM_165524   741   173 CG30503-RB FBtr0299802  NM_001144140   1842   173
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG30503-PA   FBpp0088075   19.3   173   4.84     NP_724557   AAF59257 CG30503-PB   FBpp0289080   19.3   173   4.84     NP_001137612   ACL83066
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phospholipase A2, active site (IPR013090) Phospholipase A2 domain (IPR016090) Phospholipase A2 (IPR001211)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF59257   AE013599 ACL83066   AW941496   AY094932 AAM11285   BE975450   BI570676   BI572603   BI590663   BI592779   BI610154   BI619815   BI621824   BI622208   BI625046   BT003452   CK135549   CO314227   EC065373   EL883871
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7JX94
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult heart, adult fat body, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval fat body, larval salivary gland, adult spermathecae, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female  (42) head, mated 1-day female    14 head, mated 4-day female  (27) head, mated 20-day female  (30) head, mated 1-day male    23 head, mated 4-day male  (27) head, mated 20-day male  (39) salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female  (42) head, mated 1-day female    14 head, mated 4-day female  27 head, mated 20-day female  30 head, mated 1-day male    23 head, mated 4-day male  27 head, mated 20-day male  (39) salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    10 central nervous system, larvae L3    8 central nervous system, pupae P8    10 head, virgin 1-day female    10 head, virgin 4-day female    24 head, virgin 20-day female    42 head, mated 1-day female    14 head, mated 4-day female    27 head, mated 20-day female    30 head, mated 1-day male    23 head, mated 4-day male    27 head, mated 20-day male    39 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    5 digestive system, 4-day adult    4 digestive system, 20-day adult    5 fat body, larvae L3 wandering    11 fat body, white prepupae    2 fat body, pupae P8    10 carcass, larvae L3 wandering    6 carcass, 1-day adult    11 carcass, 4-day adult    15 carcass, 20-day adult    24 ovary, virgin 4-day female    5 ovary, mated 4-day female    4 testis, mated 4-day male    4 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1  (34) larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day  (28) adult male 30day  (27) adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1  (34) larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day  28 adult male 30day  27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    15 embryo 02-04hr    15 embryo 04-06hr    12 embryo 06-08hr    13 embryo 08-10hr    12 embryo 10-12hr    13 embryo 12-14hr    12 embryo 14-16hr    19 embryo 16-18hr    9 embryo 18-20hr    11 embryo 20-22hr    25 embryo 22-24hr    24 larva L1    34 larva L2    25 larva L3 12hr old    21 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    13 white prepupae new    11 white prepupae 12hr    11 white prepupae 24hr    15 pupae 2d postWPP    24 pupae 3d postWPP    10 pupae 4d postWPP    11 adult male 01day    21 adult male 05day    28 adult male 30day    27 adult female 01day    17 adult female 05day    18 adult female 30day    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    17 Schneider line 2 Sg4    8 embryonic 1182-4H    8 embryonic GM2    10 embryonic Kc167    6 embryonic S1    10 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    10 wing disc ML-DmD8    4 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    6 wing disc ML-DmD21    10 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    12 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    10 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    7 ovary fGS/OSS    9 ovary OSC    4 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    4 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    9 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_20 mE1_20_mRNA_expression_cluster_16
External Data & Images
Linkouts	BDGP expression data • LD02291 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050503 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30503-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG30503GD3757 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG30503 Class Mutagen Stocks Known lesion CG30503G7963 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG30503 Class Mutagen Stocks Known lesion CG30503GD3757 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3757} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}κB-RasG7963 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
calcium ion binding inferred from electronic annotation with InterPro:IPR001211 (FlyBase Curators et al., 2004-) phospholipase A2 activity inferred from electronic annotation with InterPro:IPR001211, InterPro:IPR013090 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
lipid catabolic process inferred from electronic annotation with InterPro:IPR001211, InterPro:IPR013090 (FlyBase Curators et al., 2004-) phospholipid metabolic process inferred from electronic annotation with InterPro:IPR013090 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_dicistronic_mRNA (FlyBase Genome Annotators, 2008) nuclear_gene (FlyBase Genome Annotators, 2008) protein_coding_gene (FlyBase Genome Annotators, 2008)
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG30503 - RpS21 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG30503 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 73199 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0050503 DroID - A comprehensive database of gene and protein interactions. • FBgn0050503 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246656
Orthologs
OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6N5WHB Dipteran inclusive ortholog search EOG6K6GDH Insect inclusive ortholog search EOG6DFNJX Arthropod inclusive ortholog search EOG6DBRX0 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6N5WHB)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG30503     Drosophila simulans   Dsim\GD10259 Y   Drosophila sechellia   Dsec\GM20797 Y   Drosophila erecta   Dere\GG10751 Y   Drosophila yakuba   Dyak\GE24036 Y   Drosophila ananassae   Dana\GF11953 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA15891 Y   Drosophila persimilis   Dper\GL10932 Y   Drosophila willistoni   Dwil\GK22012 Y   Drosophila virilis   Dvir\GJ20552 Y   Drosophila mojavensis   Dmoj\GI20819 Y   Drosophila grimshawi   Dgri\GH20736 Y
Orthologs in non-Drosophila Dipterans (EOG6K6GDH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014113 Y Anopheles gambiae Malaria mosquito  Agam\AGAP010879 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001437 Y
Orthologs in non-Dipteran Insects (EOG6DFNJX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB48228 Y Atta cephalotes Leafcutter ant  Acep\ACEP12116 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17620 Y Linepithema humile Argentine ant  Lhum\LH24082 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB22568 Y Solenopsis invicta Red fire ant  Sinv\SINV22549 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012926 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012929 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012928 Y Bombyx mori Silkmoth  Bmor\BGIBMGA010989 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012910 Y Tribolium castaneum Red flour beetle  Tcas\TC013419 Y Tribolium castaneum Red flour beetle  Tcas\TC002563 Y
Orthologs in non-Insect Arthropods (EOG6DBRX0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW014957 Y Ixodes scapularis Deer tick  Isca\ISCW020728 Y Ixodes scapularis Deer tick  Isca\ISCW008898 Y Ixodes scapularis Deer tick  Isca\ISCW020933 Y Ixodes scapularis Deer tick  Isca\ISCW014959 Y Ixodes scapularis Deer tick  Isca\ISCW014956 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD10259 Drosophila sechellia Dsec\GM20797 Drosophila erecta Dere\GG10751 Drosophila yakuba Dyak\GE24036 Drosophila ananassae Dana\GF11953 Drosophila pseudoobscura pseudoobscura Dpse\GA15891 Drosophila persimilis Dper\GL10932 Drosophila willistoni Dwil\GK22012 Drosophila virilis Dvir\GJ20552 Drosophila mojavensis Dmoj\GI20819 Drosophila grimshawi Dgri\GH20736
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	27974 y1 w*; P{EP}κB-RasG7963 CG30503G7963
VDRC	v9036 w1118; P{GD3757}v9036/TM3
Genomic Clones ( 1 )
	BACR04G20 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 15 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH38596 RH50933
Other clones	DPiM_RH50933
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RH04315 RH05446 RH08175 RH10560 RH15086 RH53242 RH64859
Other clones	108705 bs43c12 EK235455 IP13512 RH54045
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0050503 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246656
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG30503 BcDNA:RH50933 (FlyBase, 1996-)
Additional comments	One or more of the processed transcripts for these genes contain two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG1669 (FBgn0040513), CG30503 (FBgn0050503). (FlyBase Genome Annotators, 2008) Source for merge of CG30503 BcDNA:RH50933 was TrEMBL update (date:020807). (FlyBase, 1996-)
Other Comments
	Identified with: LD02291 (BDGP-DGC) (BDGP Project Members, 2000-)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165524 NM_001144140 RefSeq (Proteins) • NP_724557 NP_001137612 DDBJ / EMBL / GenBank • AAF59257 AAM11285 ACL83066 AW941496 AY061054 AY094932 BI619815 Entrez Gene - A searchable database of RefSeq genes. • 246656 UniProtKB/TrEMBL • Q7JX94
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phospholipase A2, active site (IPR013090) Phospholipase A2 domain (IPR016090) Phospholipase A2 (IPR001211) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD02291
Linkouts
	BioGRID - A database of protein and genetic interactions • 73199 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0050503 DroID - A comprehensive database of gene and protein interactions. • FBgn0050503 DRSC - Results from RNAi screens. • FBgn0050503 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0050503 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG30503-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0050503 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 246656 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 246656 modMine - Data generated by the modENCODE project. • FBgn0050503
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BcDNA:RH50933   CG1672   CG30503 (FlyBase Genome Annotators, 2008)
Name Synonym
Secondary FlyBase IDs
	FBgn0033171 FBgn0062430
References ( 14 )
Research paper	Renault et al., 2002, Gene Expr. Patterns 2(3-4): 337--345 Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila. [FBrf0157225] Renault et al., 2002, Mech. Dev. 119(Suppl. 1): S293--S301 Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila. [FBrf0161471]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2009.6.29, BDGP_2009_0629.GenExel.xml BDGP_2009_0629.GenExel.xml [FBrf0208121] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2008, Changes affecting gene model number or type in release 5.9 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.9 of the annotated D.melanogaster genome. [FBrf0204763] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Curated genome annotation	Li, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126682]