transmembrane protein - component of smooth septate junctions, functions cooperates with Tetraspanin 2A and Snakeskin to organize septate junctions - midgut - Malpighian tubules
Please see the JBrowse view of Dmel\mesh for information on other features
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Gene model reviewed during 5.53
Forms a complex with Ssk and Tsp2A (PubMed:26848177). Interacts with Ssk; the interaction may be necessary for the localization of both proteins to the cell apicolateral region (PubMed:22854041).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mesh using the Feature Mapper tool.
Comment: outer epithelial layer
Comment: outer epithelial layer
GBrowse - Visual display of RNA-Seq signals
View Dmel\mesh in GBrowse 23-102
3-102
3-99.1
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: mesh CG31004
Source for merge of: CG15560 CG12074
Source for merge of: CG31004 anon-WO0140519.233
Annotations CG12074, CG15560 merged as CG31004 in release 3 of the genome annotation.
Source for merge of CG15560 CG12074 was a shared cDNA ( date:010720 ).
Source for merge of CG31004 anon-WO0140519.233 was sequence comparison ( date:051113 ).
mesh is required for smooth septate junction formation in the midgut.
The gene is named 'mesh' for its immunofluorescence staining pattern in the midgut.