Gene Dmel\CG31126

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General Information

Symbol

Dmel\CG31126

Species

D. melanogaster

Name

Annotation symbol

CG31126

Feature type

protein_coding_gene

FlyBase ID

FBgn0051126

Gene Model Status

Current

Stock availability

6 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

96A14-96A14

Sequence location

3R:20,485,343..20,485,987 [+]

Genomic Maps

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Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG31126 (FBgn0051126). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neuron projection morphogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: BolA protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1636684_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG31126. Gene sequence location is 3R:20485343..20485987.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

96A14-96A14

Limits computationally determined from genome sequence between P{PZ}crb⁰⁷²⁰⁷&P{PZ}BRWD3⁰⁵⁸⁴² and P{EP}CycB3^EP3127

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG31126 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG31126-RA

FBtr0084663

NM_170162

589

150

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG31126-PA

FBpp0084043

17.0

150

9.92

NP_733027

AAF56322

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BolA protein (IPR002634)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VC53

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult testis, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		248.05
Larval Midgut		97.3
Larval Hindgut		144.2
Larval Malpighian Tubules		84.1
Larval Fat Body		94.2
Larval Salivary Gland		137.6
Larval Trachea		127.85
Larval Carcass		139.975
Adult Head		164.3
Adult Eye		132.15
Adult Brain		240
Adult Thoracic-Abdominal Ganglion		289.6
Adult Crop		109.1
Adult Midgut		145.6
Adult Hindgut		156.1
Adult Malpighian Tubules		143.2
Adult Fat Body		172.1
Adult Salivary Gland		218
Adult Heart		162.7
Adult VirginFemale Spermatheca		114.1
Adult InseminatedFemale Spermatheca		99.5
Adult Ovary		223.3
Adult Testis		241.8
Adult Male Accessory Gland		73.7
Adult Carcass		188.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	164.3
NA	Eye	132.15
NA	Brain	240
248.05	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	289.6
NA	Crop	109.1
97.3	Midgut	145.6
144.2	Hindgut	156.1
84.1	Malpighian Tubules	143.2
94.2	Fat Body	172.1
137.6	Salivary Gland	218
NA	Heart	162.7
127.85	Trachea	NA
NA	VirginFemale Spermatheca	114.1
NA	InseminatedFemale Spermatheca	99.5
NA	Ovary	223.3
NA	Testis	241.8
NA	Male Accessory Gland	73.7
139.975	Carcass	188.4

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(30)
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		(31)
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		(30)
ovary, mated 4-day female		(36)
testis, mated 4-day male		(60)
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		(36)
testis, mated 4-day male		(60)
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		30
central nervous system, larvae L3		23
central nervous system, pupae P8		16
head, virgin 1-day female		23
head, virgin 4-day female		20
head, virgin 20-day female		11
head, mated 1-day female		19
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		21
head, mated 4-day male		26
head, mated 20-day male		26
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		9
digestive system, larvae L3 wandering		8
digestive system, 1-day adult		15
digestive system, 4-day adult		19
digestive system, 20-day adult		11
fat body, larvae L3 wandering		6
fat body, white prepupae		11
fat body, pupae P8		31
carcass, larvae L3 wandering		17
carcass, 1-day adult		16
carcass, 4-day adult		21
carcass, 20-day adult		17
ovary, virgin 4-day female		30
ovary, mated 4-day female		36
testis, mated 4-day male		60
accessory gland, mated 4-day male		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(39)
embryo 02-04hr		23
embryo 04-06hr		(30)
embryo 06-08hr		(29)
embryo 08-10hr		(32)
embryo 10-12hr		(47)
embryo 12-14hr		(37)
embryo 14-16hr		(38)
embryo 16-18hr		(37)
embryo 18-20hr		(31)
embryo 20-22hr		(29)
embryo 22-24hr		(30)
larva L1		(53)
larva L2		(64)
larva L3 12hr old		(42)
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		(36)
pupae 3d postWPP		(46)
pupae 4d postWPP		25
adult male 01day		(33)
adult male 05day		(31)
adult male 30day		(29)
adult female 01day		(31)
adult female 05day		(33)
adult female 30day		(38)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(39)
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		(47)
embryo 12-14hr		(37)
embryo 14-16hr		(38)
embryo 16-18hr		(37)
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		(53)
larva L2		(64)
larva L3 12hr old		(42)
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		(36)
pupae 3d postWPP		(46)
pupae 4d postWPP		25
adult male 01day		(33)
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		(33)
adult female 30day		(38)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		23
embryo 04-06hr		30
embryo 06-08hr		29
embryo 08-10hr		32
embryo 10-12hr		47
embryo 12-14hr		37
embryo 14-16hr		38
embryo 16-18hr		37
embryo 18-20hr		31
embryo 20-22hr		29
embryo 22-24hr		30
larva L1		53
larva L2		64
larva L3 12hr old		42
larva L3 puffstage 1-2		14
larva L3 puffstage 3-6		17
larva L3 puffstage 7-9		18
white prepupae new		21
white prepupae 12hr		19
white prepupae 24hr		20
pupae 2d postWPP		36
pupae 3d postWPP		46
pupae 4d postWPP		25
adult male 01day		33
adult male 05day		31
adult male 30day		29
adult female 01day		31
adult female 05day		33
adult female 30day		38
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(45)
Schneider line 2 Sg4		(34)
embryonic 1182-4H		(31)
embryonic GM2		21
embryonic Kc167		(33)
embryonic S1		(64)
embryonic S3		(34)
leg disc CME L1		(37)
wing disc CME-W2		(45)
wing disc ML-DmD8		21
wing disc ML-DmD9		(35)
wing disc ML-DmD16-c3		(32)
wing disc ML-DmD21		(47)
wing disc ML-DmD32		(45)
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		(43)
antennal disc ML-DmD20-c5		(44)
mixed discs ML-DmD4-c1		(40)
CNS ML-DmBG1-c1		(71)
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		(37)
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(45)
Schneider line 2 Sg4		(34)
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		(33)
embryonic S1		(64)
embryonic S3		(34)
leg disc CME L1		(37)
wing disc CME-W2		(45)
wing disc ML-DmD8		21
wing disc ML-DmD9		(35)
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		(47)
wing disc ML-DmD32		(45)
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		(43)
antennal disc ML-DmD20-c5		(44)
mixed discs ML-DmD4-c1		(40)
CNS ML-DmBG1-c1		(71)
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		(37)
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		45
Schneider line 2 Sg4		34
embryonic 1182-4H		31
embryonic GM2		21
embryonic Kc167		33
embryonic S1		64
embryonic S3		34
leg disc CME L1		37
wing disc CME-W2		45
wing disc ML-DmD8		21
wing disc ML-DmD9		35
wing disc ML-DmD16-c3		32
wing disc ML-DmD21		47
wing disc ML-DmD32		45
haltere disc ML-DmD17-c3		20
eye-antennal disc ML-DmD11		43
antennal disc ML-DmD20-c5		44
mixed discs ML-DmD4-c1		40
CNS ML-DmBG1-c1		71
CNS ML-DmBG2-c2		25
tumorous blood cells mbn2		18
ovary fGS/OSS		23
ovary OSC		37
ovary OSS		10
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		(32)
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		(55)
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		(27)
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		(55)
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		10
cold shock, 4-day adult		4
heat shock, 4-day adult		25
Cadmium 50 mM 6 hrs, larvae L3		21
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		17
Cadmium 100 mM 48 hrs, 4-day adult		32
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		55
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		17
Ethanol 5% 3 hrs, larvae L3		21
Ethanol 10% 3 hrs, larvae L3		15
Caffeine 1.5 mg/ml 4 hrs, larvae L3		10
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		26
Caffeine 25 mg/ml 48 hrs, 4-day adult		17
Paraquat 5 mM 48 hrs, 4-day adult		27
Paraquat 10 mM 48 hrs, 4-day adult		24
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		19
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0051126

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG31126-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG31126	Class	Mutagen	Stocks	Known lesion
CG31126^EY23480			1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG31126	Mutagen	Stocks	Known lesion
CG31126^GD13471	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG31126^GD17428	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG31126^KK109312	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD13471}

P{GD17428}

P{KK109312}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}CG31126^EY23480

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

There is no information supporting a cellular component or molecular function term for this gene.

(Based on a review of available data on: 2004-05-11)

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

neuron projection morphogenesis

inferred from mutant phenotype

(Sepp et al., 2008)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG31126 - CG10306

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

CG31126 - mRpS24

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG31126 allele

Gene

References

External Data

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0051126

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0051126

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

326121

Orthologs

OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6T78Q1

Dipteran inclusive ortholog search

EOG6R7VMB

Insect inclusive ortholog search

EOG6W9H1S

Arthropod inclusive ortholog search

EOG666T3R

Metazoa inclusive ortholog search

EOG6CZQBG

Orthologs in Drosophila Species (EOG6T78Q1)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA16028

Drosophila persimilis

Dper\GL13616

Drosophila willistoni

Dwil\GK10967

Drosophila virilis

Dvir\GJ23647

Drosophila mojavensis

Dmoj\GI24016

Drosophila grimshawi

Dgri\GH18440

Orthologs in non-Drosophila Dipterans (EOG6R7VMB)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003755

Anopheles gambiae

Malaria mosquito

Agam\AGAP003706

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ005771

Orthologs in non-Dipteran Insects (EOG6W9H1S)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB47137

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007792

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH19440

Atta cephalotes

Leafcutter ant

Acep\ACEP24632

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO15363

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL17133

Linepithema humile

Argentine ant

Lhum\LH18746

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB17167

Solenopsis invicta

Red fire ant

Sinv\SINV25270

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI001337

Bombyx mori

Silkmoth

Bmor\BGIBMGA008047

Pediculus humanus

Human body louse

Phum\PHUM567520

Tribolium castaneum

Red flour beetle

Tcas\TC011286

Tribolium castaneum

Red flour beetle

Tcas\TC011285

Orthologs in non-Insect Arthropods (EOG666T3R)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_43049

Ixodes scapularis

Deer tick

Isca\ISCW004806

Orthologs in non-Arthropod Metazoa (EOG6CZQBG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\K11H12.1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_017745gn

Danio rerio

Zebrafish

Drer\zgc:101119

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000033155

Mus musculus

House mouse

Mmus\Bola1

Rattus norvegicus

Norway rat

Rnor\Bola1

Homo sapiens

Human

Hsap\BOLA1

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\BOLA1

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA16028

Drosophila persimilis

Dper\GL13616

Drosophila willistoni

Dwil\GK10967

Drosophila virilis

Dvir\GJ23647

Drosophila mojavensis

Dmoj\GI24016

Drosophila grimshawi

Dgri\GH18440

Stocks & Reagents

Stocks Listed in FlyBase ( 6 )

Bloomington

22638

y¹ w^67c23; P{EPgy2}CG31126^EY23480/TM3, Sb¹ Ser¹

VDRC

v108407

P{KK109312}VIE-260B

v49276

w¹¹¹⁸; P{GD17428}v49276

v23392

w¹¹¹⁸; P{GD13471}v23392/TM3

v23395

w¹¹¹⁸; P{GD13471}v23395/TM3

v49277

w¹¹¹⁸; P{GD17428}v49277/TM3

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 12 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

IP05796

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

AT01282

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0051126

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

326121

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

Annotation CG13621 renamed CG31126 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_170162

RefSeq (Proteins)

•

NP_733027

DDBJ / EMBL / GenBank

•

AAF56322

Entrez Gene - A searchable database of RefSeq genes.

•

326121

UniProtKB/TrEMBL

•

Q9VC53

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BolA protein (IPR002634)

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0051126

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0051126

DRSC - Results from RNAi screens.

•

FBgn0051126

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0051126

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG31126-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0051126

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

326121

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

326121

modMine - Data generated by the modENCODE project.

•

FBgn0051126

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG13621

(Luschnig, 2003.12.17, )

CG31126

(Farny et al., 2008, Keleman et al., 2009.8.5, Cammarato et al., 2011, Sepp et al., 2008)

Name Synonym

Secondary FlyBase IDs

FBgn0039216

References ( 16 )

Research paper

Farny et al., 2008, Genes Dev. 22(1): 66--78: Definition of global and transcript-specific mRNA export pathways in metazoans. [FBrf0200863]
Sepp et al., 2008, PLoS Genet. 4(7): e1000111: Identification of neural outgrowth genes using genome-wide RNAi. [FBrf0205132]

Supplementary material

Cammarato et al., 2011, PLoS ONE 6(4):: Table S1. Proteins & Peptides. [FBrf0214682]
Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]

Review

Zdobnov et al., 2002, Science 298(5591): 149--159: Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. [FBrf0152342]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project: DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Luschnig, 2003.12.17, Existence-uncertain genes.: Existence-uncertain genes. [FBrf0173248]

FlyBase analysis

FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.: Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.: Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]