FB2020_01, released Feb 12, 2020

Gene: Dmel\Jupiter

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General Information
Symbol
Dmel\Jupiter
Species
D. melanogaster
Name
Jupiter
Annotation Symbol
CG31363
Feature Type
protein_coding_gene
FlyBase ID
FBgn0051363
Gene Model Status
Current
Stock Availability
20 publicly available
Gene Snapshot
In progress.Contributions welcome.
Other Summaries
Key Links
Genomic Location
Cytogenetic map
86E11-86E13
Sequence location
3R:11,590,386..11,619,906 [-]
Recombination map

3-51

RefSeq locus
NT_033777 REGION:11590386..11619906
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Protein Family (UniProt)
Belongs to the MAP Jupiter family. (Q9I7K0)
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
microtubule binding; structural constituent of cytoskeleton
Predictions / Assertions
-
Summaries
Protein Function (UniProtKB)
Binds to all microtubule populations.
(UniProt, Q9I7K0)
Gene Model and Products
Number of Transcripts
7
Number of Unique Polypeptides
7

Please see the GBrowse view of Dmel\Jupiter or the JBrowse view of Dmel\Jupiter for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Graveley et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Jupiter-RA
FBtr0082456
NM_169405
1535
197
Jupiter-RB
FBtr0082457
NM_169409
1583
185
Jupiter-RC
FBtr0082455
NM_169407
1581
197
Jupiter-RD
FBtr0082452
NM_169404
1517
191
Jupiter-RE
FBtr0082454
NM_169408
1658
208
Jupiter-RH
FBtr0082453
NM_169406
1550
202
Jupiter-RI
FBtr0335232
NM_001275546
1259
105
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Jupiter-PA
FBpp0081932
20.9
197
10.58
NP_731596
AAF54661
Jupiter-PB
FBpp0081933
19.7
185
4.89
NP_731600
AAG22142
Jupiter-PC
FBpp0081931
20.9
197
10.65
NP_731598
AAF54662
Jupiter-PD
FBpp0081928
20.2
191
10.25
NP_731595
AAN13515
Jupiter-PE
FBpp0081930
22.3
208
10.75
NP_731599
AAG22143
Jupiter-PH
FBpp0081929
21.6
202
10.42
NP_731597
AAN13516
Jupiter-PI
FBpp0307219
11.2
105
8.47
NP_001262475
AGB95857
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Jupiter using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (7 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
microtubule binding
inferred from direct assay
(Karpova et al., 2006)
structural constituent of cytoskeleton
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
positive regulation of microtubule polymerization
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
microtubule associated complex
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
colocalizes_with microtubule
inferred from high throughput direct assay
(Lye et al., 2014)
nucleus
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
Terms Based on Predictions or Assertions (0 terms)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
microtubule associated complex
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
colocalizes_with microtubule
inferred from high throughput direct assay
(Lye et al., 2014)
nucleus
inferred from direct assay
(assigned by UniProt )
(Karpova et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Jupiter in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 4-6
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 23 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Jupiter
Transgenic constructs containing regulatory region of Jupiter
Deletions and Duplications ( 2 )
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\JPT1
3 of 15
Yes
Yes
Hsap\JPT2
2 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Jpt1
3 of 15
Yes
Yes
Mmus\Jpt2
2 of 15
No
No
Rattus norvegicus (Norway rat) (3)
Rnor\Jpt1
2 of 13
Yes
Yes
Rnor\Jpt2
2 of 13
Yes
No
Rnor\RGD1559903
2 of 13
Yes
No
Xenopus tropicalis (Western clawed frog) (1)
Xtro\jpt1
1 of 12
Yes
Yes
Danio rerio (Zebrafish) (3)
Drer\jpt1b
4 of 15
Yes
Yes
Drer\jpt1a
3 of 15
No
Yes
Drer\jpt2
2 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (0)
No records found.
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190G9E )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\Jupiter
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00011003
Drosophila simulans
Dsim\GD20653
Drosophila sechellia
Dsec\GM26090
Drosophila erecta
Dere\GG17211
Drosophila yakuba
Dyak\GE10105
Drosophila ananassae
Dana\GF16635
Drosophila pseudoobscura pseudoobscura
Dpse\GA22255
Drosophila pseudoobscura pseudoobscura
Dpse\GA27493
Drosophila persimilis
Dper\GL12395
Drosophila willistoni
Dwil\GK11035
Drosophila virilis
Dvir\GJ15816
Drosophila virilis
Dvir\GJ10600
Drosophila mojavensis
Dmoj\GI23754
Drosophila mojavensis
Dmoj\GI11035
Drosophila grimshawi
Dgri\GH17288
Drosophila grimshawi
Dgri\GH12623
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915081U )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17018182
Glossina morsitans
Tsetse fly
Gmor\GMOY008531
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12956
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL014490
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL014194
Anopheles darlingi
American malaria mosquito
Adar\ADAC009436
Anopheles gambiae
Malaria mosquito
Agam\AGAP001372
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016614
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016615
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0JFB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Apis florea
Little honeybee
Aflo\2160126946
Apis mellifera
Western honey bee
Amel\GB49588
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18049
Bombus terrestris
Buff-tailed bumblebee
Bter\15216029
Linepithema humile
Argentine ant
Lhum\LH23590
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0001aa
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG009057
Pediculus humanus
Human body louse
Phum\PHUM491830
Rhodnius prolixus
Kissing bug
Rpro\RPRC015026
Cimex lectularius
Bed bug
Clec\CLEC008698
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI55078
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI067564
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_00528
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0MTB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR003675
Ixodes scapularis
Black-legged tick
Isca\ISCW009705
Stegodyphus mimosarum
African social velvet spider
Smim\KFM72063.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g03540
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (1)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG1943
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    JPT1; Jupiter microtubule associated homolog 1
    3 of 15
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Summary of Genetic Interactions
        esyN Network Diagram
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        3R
        Recombination map

        3-51

        Cytogenetic map
        86E11-86E13
        Sequence location
        3R:11,590,386..11,619,906 [-]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        86E11-86E13
        Limits computationally determined from genome sequence between P{PZ}tho1&P{PZ}l(3)0462905275 and P{EP}Lk6EP886
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location

        3-51

        (FlyBase, 2016)

        3-48.6

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (20)
        Genomic Clones (29)
        cDNA Clones (295)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequences
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         

        polyclonal

        (Karpova et al., 2006)
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of

        Source for identity of: Jupiter CG31363

        (Karpova et al., 2005)
        Source for database merge of

        Source for merge of: CG31363 anon- EST:Liang-1.76

        (Ashburner, 2004.6.30)

        Source for merge of: CG31363 BEST:LP05168

        (Rana, 2004.7.8)

        Source for merge of: CG31363 BcDNA:RH53211

        (FlyBase, 1996-)

        Source for merge of: CG17238 CG18762 CG18763

        (FlyBase Genome Annotators, 2002-2003)

        Source for merge of: CG31363 BcDNA:LD43690

        (FlyBase, 1996-)

        Source for merge of: CG31363 BcDNA:LD21358

        (FlyBase, 1996-)

        Source for merge of: Jupiter anon-WO0140519.173

        (FlyBase, 1996-)

        Source for merge of: CG31363 BcDNA:GH06373

        (FlyBase, 1996-)
        Additional comments

        Annotations CG17238, CG18762 and CG18763 merged as CG31363 in release 3 of the genome annotation.

        (FlyBase Genome Annotators, 2002-2003)

        Source for merge of CG31363 BcDNA:RH53211 was a shared cDNA ( date:030728 ).

        (FlyBase, 1996-)

        Source for merge of CG31363 BcDNA:LD43690 was a shared cDNA ( date:030728 ).

        (FlyBase, 1996-)

        Source for merge of CG31363 BcDNA:LD21358 was a shared cDNA ( date:030728 ).

        (FlyBase, 1996-)

        Source for merge of Jupiter anon-WO0140519.173 was sequence comparison ( date:051113 ).

        (FlyBase, 1996-)

        Source for merge of CG31363 BcDNA:GH06373 was a shared cDNA ( date:030728 ).

        (FlyBase, 1996-)
        Other Comments
        Origin and Etymology
        Discoverer
        Etymology
        Identification
        External Crossreferences and Linkouts ( 80 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Synonyms and Secondary IDs (14)
        Reported As
        Symbol Synonym
        BEST:LP05168
        BcDNA:GH06373
        BcDNA:LD21358
        BcDNA:LD43690
        BcDNA:RH53211
        CG17238
        (Siller and Doe, 2008, Stumpff et al., 2004, Morin et al., 2001)
        CG18762
        CG18763
        (Cooley et al., 2002.10-2003.5)
        CG31363
        (Hosono et al., 2015, Rosa-Ferreira et al., 2015, Kim et al., 2010, Keleman et al., 2009.8.5, Li et al., 2009, Perkins et al., 2009, Wen et al., 2008, Quinones-Coello, 2007, Casillas et al., 2006, Karpova et al., 2006, Burnette et al., 2005, Pandey et al., 2005, Ashburner, 2004.6.30, Rana, 2004.7.8, Biggin, 1999.2.5, FlyBase, 1996-)
        Jupiter
        (Meltzer et al., 2019, Takeda et al., 2018, Wang et al., 2018, Hu et al., 2017.6.13, Derivery et al., 2015, Duff et al., 2015, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Hughes et al., 2014, Lye et al., 2014, Kwon et al., 2013, Lu et al., 2013, Morais-de-Sá and Sunkel, 2013, Sakuma et al., 2013, Sen et al., 2013, Fischer et al., 2012, Ganguly et al., 2012, Graze et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Peng et al., 2012, Telley et al., 2012, Abruzzi et al., 2011, Friedman et al., 2011, Morris and Spradling, 2011, Kong et al., 2010, Orsi et al., 2010, Bozoky et al., 2009, Szalontai et al., 2009, Chabu and Doe, 2008, Giansanti et al., 2008, Buszczak et al., 2007, Rolls et al., 2007, Karpova et al., 2006, McIntyre et al., 2006, Zraly et al., 2006)
        anon-EST:Liang-1.76
        anon-WO0140519.173
        clone 1.76
        (Liang and Biggin, 1998)
        jupiter
        (Cabernard and Doe, 2009, McIntyre et al., 2006)
        Name Synonyms
        Jupiter
        (Juhász et al., 2012, Xie and Auld, 2011, McDonald et al., 2008)
        jupiter
        (Karpova et al., 2006)
        Secondary FlyBase IDs
        • FBgn0025976
        • FBgn0037919
        • FBgn0042108
        • FBgn0042109
        • FBgn0044704
        • FBgn0045776
        • FBgn0063691
        • FBgn0064799
        • FBgn0064919
        • FBgn0064972
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        References (106)