Gene Dmel\CG31441

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General Information

Symbol

Dmel\CG31441

Species

D. melanogaster

Name

Annotation symbol

CG31441

Feature type

protein_coding_gene

FlyBase ID

FBgn0051441

Gene Model Status

Current

Stock availability

1 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

86D8-86D8

Sequence location

3R:7,062,008..7,063,346 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG31441 (FBgn0051441). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger C2H2-type/integrase DNA-binding domain; Zinc finger, AD-type; Zinc finger, C2H2; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1640493_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG31441. Gene sequence location is 3R:7062008..7063346.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

86D8-86D8

Limits computationally determined from genome sequence between P{EP}EP3340^EP3340 and P{PZ}tho¹&P{PZ}l(3)04629⁰⁵²⁷⁵

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG31441 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.49

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG31441-RA

FBtr0082355

NM_169382

1219

341

CG31441-RB

FBtr0339400

1223

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG31441-PA

FBpp0081831

40.0

341

8.49

NP_731558

AAF54620

CG31441-PB

FBpp0308492

5.6

9.90

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, C2H2 (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)

Zinc finger, C2H2-like (IPR015880)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VGQ6

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		42
Larval Midgut		21.3
Larval Hindgut		22.7
Larval Malpighian Tubules		29.6
Larval Fat Body		36.6
Larval Salivary Gland		19.7
Larval Trachea		25.975
Larval Carcass		20.125
Adult Head		27.1
Adult Eye		29.475
Adult Brain		51
Adult Thoracic-Abdominal Ganglion		39.4
Adult Crop		52.2
Adult Midgut		23.8
Adult Hindgut		30.4
Adult Malpighian Tubules		34.8
Adult Fat Body		44.7
Adult Salivary Gland		40.2
Adult Heart		30.175
Adult VirginFemale Spermatheca		37
Adult InseminatedFemale Spermatheca		39.2
Adult Ovary		66.6
Adult Testis		26.1
Adult Male Accessory Gland		19.9
Adult Carcass		32.7
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	27.1
NA	Eye	29.475
NA	Brain	51
42	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	39.4
NA	Crop	52.2
no informative data	Midgut	no informative data
22.7	Hindgut	30.4
29.6	Malpighian Tubules	34.8
36.6	Fat Body	44.7
19.7	Salivary Gland	40.2
NA	Heart	30.175
25.975	Trachea	NA
NA	VirginFemale Spermatheca	37
NA	InseminatedFemale Spermatheca	39.2
NA	Ovary	66.6
NA	Testis	26.1
NA	Male Accessory Gland	no informative data
no informative data	Carcass	32.7

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		6
central nervous system, larvae L3		6
central nervous system, pupae P8		5
head, virgin 1-day female		3
head, virgin 4-day female		7
head, virgin 20-day female		4
head, mated 1-day female		4
head, mated 4-day female		5
head, mated 20-day female		4
head, mated 1-day male		5
head, mated 4-day male		5
head, mated 20-day male		8
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		5
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		3
fat body, white prepupae		3
fat body, pupae P8		12
carcass, larvae L3 wandering		5
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		3
ovary, virgin 4-day female		19
ovary, mated 4-day female		23
testis, mated 4-day male		4
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		16
embryo 02-04hr		16
embryo 04-06hr		13
embryo 06-08hr		9
embryo 08-10hr		8
embryo 10-12hr		7
embryo 12-14hr		5
embryo 14-16hr		4
embryo 16-18hr		4
embryo 18-20hr		3
embryo 20-22hr		2
embryo 22-24hr		2
larva L1		3
larva L2		4
larva L3 12hr old		2
larva L3 puffstage 1-2		4
larva L3 puffstage 3-6		5
larva L3 puffstage 7-9		6
white prepupae new		5
white prepupae 12hr		7
white prepupae 24hr		6
pupae 2d postWPP		5
pupae 3d postWPP		4
pupae 4d postWPP		5
adult male 01day		5
adult male 05day		4
adult male 30day		4
adult female 01day		6
adult female 05day		9
adult female 30day		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(34)
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(34)
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		34
Schneider line 2 Sg4		7
embryonic 1182-4H		10
embryonic GM2		13
embryonic Kc167		13
embryonic S1		8
embryonic S3		10
leg disc CME L1		11
wing disc CME-W2		15
wing disc ML-DmD8		8
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		9
wing disc ML-DmD21		5
wing disc ML-DmD32		9
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		8
mixed discs ML-DmD4-c1		8
CNS ML-DmBG1-c1		16
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		8
ovary fGS/OSS		15
ovary OSC		8
ovary OSS		7
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		7
cold shock, 4-day adult		4
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		4
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		17
Copper 0.5 mM 12 hrs, larvae L3		7
Copper 15 mM 48 hrs, 4-day adult		14
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		16
Ethanol 5% 3 hrs, larvae L3		4
Ethanol 10% 3 hrs, larvae L3		3
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		13
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		3
Rotenone 8 μg 12 hrs, larvae L3		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD25880

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0051441

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG31441-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG31441

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal | pupal stage, with Scer\GAL4^pnr-MD237

CG31441^GD10260

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG31441	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG31441	Mutagen	Stocks	Known lesion
CG31441^GD10260	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG31441^KK103228	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
CG31441^NIG.5135R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD10260}

P{KK103228}

P{NIG.5135R}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function

CV term

Evidence

References

nucleic acid binding

inferred from sequence or structural similarity with InterPro:IPR007087

(FlyBase Genome Annotators, 2002-2003)

zinc ion binding

inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component

CV term

Evidence

References

nucleus

inferred from sequence or structural similarity with InterPro:IPR007087

(FlyBase Genome Annotators, 2002-2003)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG31441 - CG3995

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG31441 allele

Gene

References

External Data

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0051441

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0051441

Orthologs

OrthoDB Orthologs (9) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG615H0V

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

No orthologs identified

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (EOG615H0V)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila willistoni

Dwil\GK13987

Drosophila virilis

Dvir\GJ22566

Drosophila mojavensis

Dmoj\GI24615

Drosophila grimshawi

Dgri\GH22379

Orthologs in non-Drosophila Dipterans (None identified)

No non-Drosophilid orthologies identified

Orthologs in non-Dipteran Insects (None identified)

No non-Dipteran orthologies identified

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (8) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila virilis

Drosophila mojavensis

Dmoj\GI24615

Drosophila grimshawi

Dgri\GH22379

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

VDRC

v21345

w¹¹¹⁸; P{GD10260}v21345

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 4 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD25880

Other clones

DPiM_LD25880

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0051441

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

326139

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Annotation CG5135 split into CG31388 and CG31441 in release 3 of the genome annotation. In addition, release 3 annotation CG31388 contains sequences corresponding to release 2 annotation CG17722.

(FlyBase Genome Annotators, 2002-2003)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_169382

RefSeq (Proteins)

•

NP_731558

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

326139

UniProtKB/TrEMBL

•

Q9VGQ6

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, C2H2 (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger C2H2-type/integrase DNA-binding domain (IPR013087)

Zinc finger, C2H2-like (IPR015880)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

LD25880

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0051441

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0051441

DRSC - Results from RNAi screens.

•

FBgn0051441

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0051441

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG31441-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0051441

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

326139

modMine - Data generated by the modENCODE project.

•

FBgn0051441

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG5135

CG31441

(Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21, Coolon et al., 2012)

Name Synonym

Secondary FlyBase IDs

FBgn0037886

References ( 15 )

Research paper

Coolon et al., 2012, Cell Rep. 2(1): 69--75: Genomic Imprinting Absent in Drosophila melanogaster Adult Females. [FBrf0219040]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project: DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

FlyBase analysis

FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]

Curated genome annotation

FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.]: [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]
Li, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126682]