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Gene Dmel\CG31469

General Information
Symbol	Dmel\CG31469	Species	D. melanogaster
Name		Annotation symbol	CG31469
Feature type	protein_coding_gene	FlyBase ID	FBgn0051469
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87F12-87F12	Sequence location	3R:9,534,881..9,535,661 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG31469 (FBgn0051469). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein dephosphorylation. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphotyrosine protein phosphatase I superfamily; Protein-tyrosine phosphatase, low molecular weight; Protein-tyrosine phosphatase/arsenate reductase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult midgut, adult salivary gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633844_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG31469. Gene sequence location is 3R:9534881..9535661.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN60548 BKN60262 HFA16510 BKN31758
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87F12-87F12   Limits computationally determined from genome sequence between P{PZ}flfl01949 and P{lacW}trxj14A6&P{PZ}trx00347
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG31469 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG31469-RA FBtr0082844  NM_169551   613   164
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG31469-PA   FBpp0082309   18.7   164   6.00     NP_731853   AAN13589
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase/arsenate reductase (IPR000106) Phosphotyrosine protein phosphatase I superfamily (IPR023485) Protein-tyrosine phosphatase, low molecular weight (IPR017867)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAN13589   BT022290   BT022346
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8ING6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0051469    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0051469 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0051469 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  (109) embryo 04-06hr  (134) embryo 06-08hr  101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2  (189) larva L3 puffstage 3-6  (202) larva L3 puffstage 7-9  (253) white prepupae new  (125) white prepupae 12hr  (138) white prepupae 24hr    94 pupae 2d postWPP  (111) pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day  (286) adult male 05day  (362) adult male 30day  (342) adult female 01day  (128) adult female 05day  (144) adult female 30day  (199) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0051469 expression level Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr  109 embryo 04-06hr  134 embryo 06-08hr  101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2  (189) larva L3 puffstage 3-6  (202) larva L3 puffstage 7-9  (253) white prepupae new  125 white prepupae 12hr  138 white prepupae 24hr    94 pupae 2d postWPP  111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day  (286) adult male 05day  (362) adult male 30day  (342) adult female 01day  128 adult female 05day  (144) adult female 30day  (199) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7 embryo 02-04hr    109 embryo 04-06hr    134 embryo 06-08hr    101 embryo 08-10hr    63 embryo 10-12hr    95 embryo 12-14hr    99 embryo 14-16hr    17 embryo 16-18hr    14 embryo 18-20hr    26 embryo 20-22hr    31 embryo 22-24hr    46 larva L1    43 larva L2    59 larva L3 12hr old    55 larva L3 puffstage 1-2    189 larva L3 puffstage 3-6    202 larva L3 puffstage 7-9    253 white prepupae new    125 white prepupae 12hr    138 white prepupae 24hr    94 pupae 2d postWPP    111 pupae 3d postWPP    59 pupae 4d postWPP    94 adult male 01day    286 adult male 05day    362 adult male 30day    342 adult female 01day    128 adult female 05day    144 adult female 30day    199 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0051469    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0051469 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult midgut, adult salivary gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0051469 expression level Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0051469 expression level Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut    89.2 Larval Hindgut    51.2 Larval Malpighian Tubules no informative data Larval Fat Body    5 Larval Salivary Gland    12 Larval Trachea    61.925 Larval Carcass    67.6 Adult Head    77.3 Adult Eye    104.875 Adult Brain    16.2 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop    130.2 Adult Midgut    155.4 Adult Hindgut    85.4 Adult Malpighian Tubules no informative data Adult Fat Body    63 Adult Salivary Gland    101.5 Adult Heart    76.85 Adult VirginFemale Spermatheca    42.8 Adult InseminatedFemale Spermatheca    68.5 Adult Ovary    3.3 Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass    111.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut     Larval Hindgut     Larval Malpighian Tubules no informative data Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion no informative data Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    77.3   NA  Eye    104.875   NA  Brain    16.2   no informative data  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    130.2   89.2  Midgut    155.4   51.2  Hindgut    85.4   no informative data  Malpighian Tubules    no informative data   5  Fat Body    63   12  Salivary Gland    101.5   NA  Heart    76.85   61.925  Trachea    NA   NA  VirginFemale Spermatheca    42.8   NA  InseminatedFemale Spermatheca    68.5   NA  Ovary    3.3   NA  Testis    no informative data   NA  Male Accessory Gland    no informative data   67.6  Carcass    111.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051469 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31469-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG31469GD13476 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG31469 Class Mutagen Stocks Known lesion CG31469c06947b 1 -- CG31469c07122 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG31469 Class Mutagen Stocks Known lesion CG31469GD13476 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG31469JF02702 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG31469KK111758 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6170 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13476} NA P{KK111758} NA P{TRiP.JF02702} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG31469c06947b NA PBac{PB}CG31469c07122 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
protein tyrosine phosphatase activity inferred from sequence or structural similarity with UniProtKB:P40347 (FlyBase Genome Annotators, 2002-2003)
Biological Process
CV term Evidence References
protein dephosphorylation inferred from sequence or structural similarity with UniProtKB:P40347 (FlyBase Genome Annotators, 2002-2003)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG31469 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0051469 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 261628
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18148 Dere\GG17027 Dgri\GH14047 Dmoj\GI24422 Dper\GL24449 Dpse\GA16272 Dsec\GM25911 Dsim\GD20478 Dvir\GJ14280 Dwil\GK13064 Dyak\GE24419
Curated drosophilid orthologs	Dpse\GA16272
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL003237-PA Aedes aegypti (mosquito) AGAP009266-PA Anopheles gambiae (mosquito) 85660 Batrachochytrium dendrobatidis (chytrid fungus) RP32428 Caenorhabditis remanei (nematode) DDB0266663 Dictyostelium discoideum (amoeba) GL50803_14456 Giardia lamblia (flagellated protozoan) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241536 FBgn0215073 FBgn0201495 FBgn0191949 FBgn0180767 FBgn0076288 FBgn0162038 FBgn0147145 FBgn0121523 FBgn0109255 FBgn0095166 CPIJ001083 CPIJ001084
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	27550 y1 v1; P{TRiP.JF02702}attP2
Harvard	- PBac{PB}CG31469c07122 - PBac{PB}Pvf2c06947, PBac{PB}Pvf2c06947a, PBac{PB}CG31469c06947b
VDRC	v102474 P{KK111758}VIE-260B v23396 w1118; P{GD13476}v23396 v23397 w1118; P{GD13476}v23397
Genomic Clones ( 2 )
	BACR03J04 BACR30G22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP04482 IP04682
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0051469 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 261628
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Annotation CG9599 split into CG31469, CG31311 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_169551 RefSeq (Proteins) • NP_731853 DDBJ / EMBL / GenBank • AAN13589 AAN13589.1 Entrez Gene - A searchable database of RefSeq genes. • 261628 UniProtKB/TrEMBL • Q8ING6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase/arsenate reductase (IPR000106) Phosphotyrosine protein phosphatase I superfamily (IPR023485) Protein-tyrosine phosphatase, low molecular weight (IPR017867)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0051469 DRSC - Results from RNAi screens. • FBgn0051469 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051469 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31469-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0051469 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 261628 InParanoid A subset of ortholog calls from InParanoid. • AAEL003237-PA Aedes aegypti (mosquito) AGAP009266-PA Anopheles gambiae (mosquito) 85660 Batrachochytrium dendrobatidis (chytrid fungus) RP32428 Caenorhabditis remanei (nematode) DDB0266663 Dictyostelium discoideum (amoeba) GL50803_14456 Giardia lamblia (flagellated protozoan) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 261628 modMine - Data generated by the modENCODE project. • FBgn0051469 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241536 FBgn0215073 FBgn0201495 FBgn0191949 FBgn0180767 FBgn0076288 FBgn0162038 FBgn0147145 FBgn0121523 FBgn0109255 FBgn0095166 CPIJ001083 CPIJ001084
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG9599   CG31469 (Keleman et al., 2009.8.5, Lai et al., 2007, Perkins et al., 2009)
Name Synonym
Secondary FlyBase IDs
	FBgn0038174 FBgn0063632
References ( 11 )
Research paper	Lai et al., 2007, Mech. Ageing Dev. 128(3): 237--249 Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. [FBrf0194081]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
Curated genome annotation	Dunn, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126662]