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Gene Dmel\CG31694

General Information
Symbol	Dmel\CG31694	Species	D. melanogaster
Name		Annotation symbol	CG31694
Feature type	protein_coding_gene	FlyBase ID	FBgn0051694
Gene Model Status	Current	Stock availability	12 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	23B7-23B8	Sequence location	2L:2,868,627..2,874,489 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG31694 (FBgn0051694). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: positive regulation of JAK-STAT cascade. 14 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-type fold; Interferon-related developmental regulator, C-terminal; Interferon-related developmental regulator, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, larval/adult fat body, larval/adult salivary gland, adult ovary, adult male reproductive system, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval trachea, adult spermathecae, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637307_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG31694. Gene sequence location is 2L:2868627..2874489.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 23B7-23B8   Limits computationally determined from genome sequence between P{PZ}oho23B03575 and P{PZ}lilli00632
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG31694 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG31694-RA FBtr0077685  NM_164511   2639   425
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG31694-PA   FBpp0077369   47.3   425   6.21     NP_722858   AAF51186
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Interferon-related developmental regulator, C-terminal (IPR006921) Interferon-related developmental regulator, N-terminal (IPR007701) Armadillo-type fold (IPR016024)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264031   AA438898   AA539737   AA567892   AE014134 AAF51186   AI108610   AI238108   AI238464   AI239083   AI260630   AI292813   AI296437   AI296572   AI403898   AI514290   AI531809   AI542854   AY119016 AAM50876   BE976524   BF492555   BF492556   BF495852   BF496557   BF497244   BF497903   BF502541   BF503072   BF503192   BH809461   BI161503   BI161504   BI164265   BI166603   BI166778   BI169890   BI172810   BI216132   BI232708   BI236576   BI242367   BI358120   BI362322   BI364171   BI365757   BI366739   BI372734   BI374899   BI485336   BI571476   BI572186   BI572252   BI572331   BI574423   BI574650   BI575109   BI578074   BI579595   BI579862   BI580553   BI581530   BI581626   BI582396   BI586884   BI587647   BI590872   BI590897   BI591231   BI612770   BI624712   BI633729   BI635380   BI640114   BP543145   BP543146   BP545925   CK131467   CK660879   CL943503   CO182180   CO182334   CO182381   CO269629   CO270710   CO279796   CO296214   CO309055   CO309408   CO310920   CO312698   CO314247   CO314818   CO315660   CO321825   CO328901   CO332189   CZ468711   CZ468712   CZ481712   EC053775   EC061275   EC067629   EC076378   EC076470   EC079242   EC082819   EC088626   EC089177   EC089199   EC206225   EC211691   EC213269   EC221126   EC225180   EC227620   EC233331   EC236301   EC240636   EC248774   EV593924   EV596729
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VQI5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, larval/adult fat body, larval/adult salivary gland, adult ovary, adult male reproductive system, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval trachea, adult spermathecae, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland    1109.9 Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut  (646.1) Larval Hindgut    451.5 Larval Malpighian Tubules  (632.5) Larval Fat Body  (698.9) Larval Salivary Gland  (847.9) Larval Trachea    304.85 Larval Carcass  (571.875) Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body  (563.9) Adult Salivary Gland  (1109.9) Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary  (614.9) Adult Testis  (664.4) Adult Male Accessory Gland  (567.8) Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland  (1109.9) Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland    1109.9 Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland    1109.9 Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut  646.1 Larval Hindgut    451.5 Larval Malpighian Tubules  632.5 Larval Fat Body  698.9 Larval Salivary Gland  (847.9) Larval Trachea    304.85 Larval Carcass  571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body  563.9 Adult Salivary Gland  (1109.9) Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary  614.9 Adult Testis  664.4 Adult Male Accessory Gland  567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland  1109.9 Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    361.25 Larval Midgut    646.1 Larval Hindgut    451.5 Larval Malpighian Tubules    632.5 Larval Fat Body    698.9 Larval Salivary Gland    847.9 Larval Trachea    304.85 Larval Carcass    571.875 Adult Head    299.4 Adult Eye    309.675 Adult Brain    337.6 Adult Thoracic-Abdominal Ganglion    431.8 Adult Crop    340.4 Adult Midgut    321.7 Adult Hindgut    219.1 Adult Malpighian Tubules    415.7 Adult Fat Body    563.9 Adult Salivary Gland    1109.9 Adult Heart    352.825 Adult VirginFemale Spermatheca    454.2 Adult InseminatedFemale Spermatheca    479.9 Adult Ovary    614.9 Adult Testis    664.4 Adult Male Accessory Gland    567.8 Adult Carcass    395.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    299.4   NA  Eye    309.675   NA  Brain    337.6   361.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    431.8   NA  Crop    340.4   646.1  Midgut    321.7   451.5  Hindgut    219.1   632.5  Malpighian Tubules    415.7   698.9  Fat Body    563.9   847.9  Salivary Gland    1109.9   NA  Heart    352.825   304.85  Trachea    NA   NA  VirginFemale Spermatheca    454.2   NA  InseminatedFemale Spermatheca    479.9   NA  Ovary    614.9   NA  Testis    664.4   NA  Male Accessory Gland    567.8   571.875  Carcass    395.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae    104 digestive system, larvae L3 wandering    132 digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering    120 carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female    151 ovary, mated 4-day female    119 testis, mated 4-day male    159 accessory gland, mated 4-day male    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (77) central nervous system, larvae L3  (40) central nervous system, pupae P8  (40) head, virgin 1-day female  (50) head, virgin 4-day female  (44) head, virgin 20-day female  (33) head, mated 1-day female  (42) head, mated 4-day female  (42) head, mated 20-day female  (32) head, mated 1-day male  (54) head, mated 4-day male  (56) head, mated 20-day male  (50) salivary gland, larvae L3 wandering  (52) salivary gland, white prepupae  (104) digestive system, larvae L3 wandering  (132) digestive system, 1-day adult  (35) digestive system, 4-day adult  (34) digestive system, 20-day adult  (32) fat body, larvae L3 wandering  (45) fat body, white prepupae  (60) fat body, pupae P8  (38) carcass, larvae L3 wandering  (120) carcass, 1-day adult  (66) carcass, 4-day adult  (54) carcass, 20-day adult  (51) ovary, virgin 4-day female  (151) ovary, mated 4-day female  (119) testis, mated 4-day male  (159) accessory gland, mated 4-day male  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae  104 digestive system, larvae L3 wandering  (132) digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering  (120) carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female  (151) ovary, mated 4-day female  (119) testis, mated 4-day male  (159) accessory gland, mated 4-day male    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae    104 digestive system, larvae L3 wandering    132 digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering    120 carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female    151 ovary, mated 4-day female    119 testis, mated 4-day male    159 accessory gland, mated 4-day male    53 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae    104 digestive system, larvae L3 wandering    132 digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering    120 carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female    151 ovary, mated 4-day female    119 testis, mated 4-day male    159 accessory gland, mated 4-day male    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (77) central nervous system, larvae L3  (40) central nervous system, pupae P8  (40) head, virgin 1-day female  (50) head, virgin 4-day female  (44) head, virgin 20-day female  (33) head, mated 1-day female  (42) head, mated 4-day female  (42) head, mated 20-day female  32 head, mated 1-day male  (54) head, mated 4-day male  (56) head, mated 20-day male  (50) salivary gland, larvae L3 wandering  (52) salivary gland, white prepupae  (104) digestive system, larvae L3 wandering  (132) digestive system, 1-day adult  (35) digestive system, 4-day adult  (34) digestive system, 20-day adult  32 fat body, larvae L3 wandering  (45) fat body, white prepupae  (60) fat body, pupae P8  (38) carcass, larvae L3 wandering  (120) carcass, 1-day adult  (66) carcass, 4-day adult  (54) carcass, 20-day adult  (51) ovary, virgin 4-day female  (151) ovary, mated 4-day female  (119) testis, mated 4-day male  (159) accessory gland, mated 4-day male  (53) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae  104 digestive system, larvae L3 wandering  132 digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering  120 carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female  (151) ovary, mated 4-day female  119 testis, mated 4-day male  (159) accessory gland, mated 4-day male    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    77 central nervous system, larvae L3    40 central nervous system, pupae P8    40 head, virgin 1-day female    50 head, virgin 4-day female    44 head, virgin 20-day female    33 head, mated 1-day female    42 head, mated 4-day female    42 head, mated 20-day female    32 head, mated 1-day male    54 head, mated 4-day male    56 head, mated 20-day male    50 salivary gland, larvae L3 wandering    52 salivary gland, white prepupae    104 digestive system, larvae L3 wandering    132 digestive system, 1-day adult    35 digestive system, 4-day adult    34 digestive system, 20-day adult    32 fat body, larvae L3 wandering    45 fat body, white prepupae    60 fat body, pupae P8    38 carcass, larvae L3 wandering    120 carcass, 1-day adult    66 carcass, 4-day adult    54 carcass, 20-day adult    51 ovary, virgin 4-day female    151 ovary, mated 4-day female    119 testis, mated 4-day male    159 accessory gland, mated 4-day male    53 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr    101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr  (47) embryo 04-06hr  (89) embryo 06-08hr  (62) embryo 08-10hr  (59) embryo 10-12hr  (55) embryo 12-14hr  (50) embryo 14-16hr  (88) embryo 16-18hr  (101) embryo 18-20hr  (85) embryo 20-22hr  (67) embryo 22-24hr  (74) larva L1  (54) larva L2  (49) larva L3 12hr old  (43) larva L3 puffstage 1-2  (51) larva L3 puffstage 3-6  (68) larva L3 puffstage 7-9  (101) white prepupae new  (94) white prepupae 12hr  (62) white prepupae 24hr  (50) pupae 2d postWPP  (61) pupae 3d postWPP  (52) pupae 4d postWPP  (71) adult male 01day  (82) adult male 05day  (83) adult male 30day  (80) adult female 01day  (68) adult female 05day  (77) adult female 30day  (81) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr  101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9  101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr    101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr    101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr  (47) embryo 04-06hr  (89) embryo 06-08hr  (62) embryo 08-10hr  (59) embryo 10-12hr  (55) embryo 12-14hr  (50) embryo 14-16hr  (88) embryo 16-18hr  (101) embryo 18-20hr  (85) embryo 20-22hr  (67) embryo 22-24hr  (74) larva L1  (54) larva L2  (49) larva L3 12hr old  (43) larva L3 puffstage 1-2  (51) larva L3 puffstage 3-6  (68) larva L3 puffstage 7-9  (101) white prepupae new  (94) white prepupae 12hr  (62) white prepupae 24hr  (50) pupae 2d postWPP  (61) pupae 3d postWPP  (52) pupae 4d postWPP  (71) adult male 01day  (82) adult male 05day  (83) adult male 30day  (80) adult female 01day  (68) adult female 05day  (77) adult female 30day  (81) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  108 embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr  101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9  101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    47 embryo 04-06hr    89 embryo 06-08hr    62 embryo 08-10hr    59 embryo 10-12hr    55 embryo 12-14hr    50 embryo 14-16hr    88 embryo 16-18hr    101 embryo 18-20hr    85 embryo 20-22hr    67 embryo 22-24hr    74 larva L1    54 larva L2    49 larva L3 12hr old    43 larva L3 puffstage 1-2    51 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    101 white prepupae new    94 white prepupae 12hr    62 white prepupae 24hr    50 pupae 2d postWPP    61 pupae 3d postWPP    52 pupae 4d postWPP    71 adult male 01day    82 adult male 05day    83 adult male 30day    80 adult female 01day    68 adult female 05day    77 adult female 30day    81 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167    139 embryonic S1    114 embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5    105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC    157 ovary OSS    52 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  (47) embryonic 1182-4H  (52) embryonic GM2  (75) embryonic Kc167  (139) embryonic S1  (114) embryonic S3  (41) leg disc CME L1  (51) wing disc CME-W2  (77) wing disc ML-DmD8  (46) wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (65) wing disc ML-DmD21  (45) wing disc ML-DmD32  (61) haltere disc ML-DmD17-c3  (46) eye-antennal disc ML-DmD11  (92) antennal disc ML-DmD20-c5  (105) mixed discs ML-DmD4-c1  (65) CNS ML-DmBG1-c1  (65) CNS ML-DmBG2-c2  (74) tumorous blood cells mbn2  (72) ovary fGS/OSS  (63) ovary OSC  (157) ovary OSS  (52) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167  (139) embryonic S1  (114) embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5  105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC  (157) ovary OSS    52 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167    139 embryonic S1    114 embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5    105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC    157 ovary OSS    52 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167    139 embryonic S1    114 embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5    105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC    157 ovary OSS    52 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  (47) embryonic 1182-4H  (52) embryonic GM2  (75) embryonic Kc167  (139) embryonic S1  (114) embryonic S3  (41) leg disc CME L1  (51) wing disc CME-W2  (77) wing disc ML-DmD8  (46) wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (65) wing disc ML-DmD21  (45) wing disc ML-DmD32  (61) haltere disc ML-DmD17-c3  (46) eye-antennal disc ML-DmD11  (92) antennal disc ML-DmD20-c5  (105) mixed discs ML-DmD4-c1  (65) CNS ML-DmBG1-c1  (65) CNS ML-DmBG2-c2  (74) tumorous blood cells mbn2  (72) ovary fGS/OSS  (63) ovary OSC  (157) ovary OSS  (52) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167  139 embryonic S1  114 embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5  105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC  (157) ovary OSS    52 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    52 embryonic GM2    75 embryonic Kc167    139 embryonic S1    114 embryonic S3    41 leg disc CME L1    51 wing disc CME-W2    77 wing disc ML-DmD8    46 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    65 wing disc ML-DmD21    45 wing disc ML-DmD32    61 haltere disc ML-DmD17-c3    46 eye-antennal disc ML-DmD11    92 antennal disc ML-DmD20-c5    105 mixed discs ML-DmD4-c1    65 CNS ML-DmBG1-c1    65 CNS ML-DmBG2-c2    74 tumorous blood cells mbn2    72 ovary fGS/OSS    63 ovary OSC    157 ovary OSS    52 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult    145 Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult    101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (41) cold shock, 4-day adult  26 heat shock, 4-day adult  (59) Cadmium 50 mM 6 hrs, larvae L3  (43) Cadmium 50 mM 12 hrs, larvae L3  (82) Cadmium 50 mM 48 hrs, 4-day adult  (79) Cadmium 100 mM 48 hrs, 4-day adult  (145) Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult  (101) Zinc 5 mM 12 hrs, larvae L3  (30) Zinc 4.5 mM 48 hrs, 4-day adult  (88) Ethanol 2.5% 3 hrs, larvae L3  (73) Ethanol 5% 3 hrs, larvae L3  (61) Ethanol 10% 3 hrs, larvae L3  (63) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (44) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (101) Caffeine 25 mg/ml 48 hrs, 4-day adult  (41) Paraquat 5 mM 48 hrs, 4-day adult  (85) Paraquat 10 mM 48 hrs, 4-day adult  (76) Rotenone 2 μg 12 hrs, larvae L3  (71) Rotenone 8 μg 12 hrs, larvae L3  (57) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult  (145) Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult  101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult    145 Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult    101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult    145 Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult    101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (41) cold shock, 4-day adult  26 heat shock, 4-day adult  (59) Cadmium 50 mM 6 hrs, larvae L3  (43) Cadmium 50 mM 12 hrs, larvae L3  (82) Cadmium 50 mM 48 hrs, 4-day adult  (79) Cadmium 100 mM 48 hrs, 4-day adult  (145) Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult  (101) Zinc 5 mM 12 hrs, larvae L3  30 Zinc 4.5 mM 48 hrs, 4-day adult  (88) Ethanol 2.5% 3 hrs, larvae L3  (73) Ethanol 5% 3 hrs, larvae L3  (61) Ethanol 10% 3 hrs, larvae L3  (63) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (44) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (101) Caffeine 25 mg/ml 48 hrs, 4-day adult  (41) Paraquat 5 mM 48 hrs, 4-day adult  (85) Paraquat 10 mM 48 hrs, 4-day adult  (76) Rotenone 2 μg 12 hrs, larvae L3  (71) Rotenone 8 μg 12 hrs, larvae L3  (57) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult  (145) Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult  101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    41 cold shock, 4-day adult    26 heat shock, 4-day adult    59 Cadmium 50 mM 6 hrs, larvae L3    43 Cadmium 50 mM 12 hrs, larvae L3    82 Cadmium 50 mM 48 hrs, 4-day adult    79 Cadmium 100 mM 48 hrs, 4-day adult    145 Copper 0.5 mM 12 hrs, larvae L3    24 Copper 15 mM 48 hrs, 4-day adult    101 Zinc 5 mM 12 hrs, larvae L3    30 Zinc 4.5 mM 48 hrs, 4-day adult    88 Ethanol 2.5% 3 hrs, larvae L3    73 Ethanol 5% 3 hrs, larvae L3    61 Ethanol 10% 3 hrs, larvae L3    63 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    101 Caffeine 25 mg/ml 48 hrs, 4-day adult    41 Paraquat 5 mM 48 hrs, 4-day adult    85 Paraquat 10 mM 48 hrs, 4-day adult    76 Rotenone 2 μg 12 hrs, larvae L3    71 Rotenone 8 μg 12 hrs, larvae L3    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_27 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LP04564 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051694 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31694-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG31694CA07748 CG31694EY11632 viable, with Scer\GAL4pnr-MD237 CG31694GD10333 Sterility Allele fertile CG31694EY11632 Phenotype manifest in Allele
Classical Alleles ( 10 )
For All Classical Alleles Show
Allele of CG31694 Class Mutagen Stocks Known lesion CG31694KG04350 P-element activity 2 -- CG316945-SZ-3215 1 -- CG31694c03550 piggyBac transposase 1 -- CG31694CB-0337-3 1 -- CG31694e03952 piggyBac transposase 1 -- CG31694EY11632 P-element activity 1 -- CG31694MI00441 1 -- CG31694NP4693 1 -- CG31694CA07748 P-element activity 0 Yes CG31694CPTI001771 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG31694 Class Mutagen Stocks Known lesion CG31694GD10333 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG31694HMS01672 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG31694KK101281 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG31694NIG.31694R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10333} NA P{KK101281} NA P{NIG.31694R} NA P{TRiP.HMS01672} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG31694EY11632 NA miscellaneous insertions Mi{MIC}CG31694MI00441 NA P{PTT-GA}CG31694CA07748 NA P{RS3}CG31694CB-0337-3 NA P{RS5}CG316945-SZ-3215 NA P{SUPor-P}CG31694KG04350 NA PBac{681.P.FSVS-1}CG31694CPTI001771 NA PBac{PB}CG31694c03550 NA PBac{RB}CG31694e03952 NA insertion of enhancer trap binary system P{GawB}CG31694NP4693 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
positive regulation of JAK-STAT cascade inferred from mutant phenotype (Muller et al., 2005)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG31694 - Aats-asn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Art2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG10496 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG10877 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG10934 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG11679 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG1234 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG14826 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG15236 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG17601 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG31637 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG31910 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG32344 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG3303 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG33523 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG3995 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG4302 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG4415 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG4951 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG5190 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG5645 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG6652 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG6937 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG7849 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG8359 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG8765 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG8801 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG8924 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG8939 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG9253 experimental knowledge based (Guruharsha et al., 2011) CG31694 - CG9281 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CG9389 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CSN4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - CanA1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Csp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Gαs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Hakai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Hcs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Hph anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Ip259 experimental knowledge based (Guruharsha et al., 2011) CG31694 - Kr-h1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Mcm3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Mcm5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Nf-YB anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Nle anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Nop56 experimental knowledge based (Guruharsha et al., 2011) CG31694 - Ns1 experimental knowledge based (Guruharsha et al., 2011) CG31694 - Ns2 experimental knowledge based (Guruharsha et al., 2011) CG31694 - Pk17E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Pten anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Ran anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Rbf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - RpLP0 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Sbp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Sk1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Socs44A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Srp68 experimental knowledge based (Guruharsha et al., 2011) CG31694 - Srp72 experimental knowledge based (Guruharsha et al., 2011) CG31694 - TfIIEα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Tg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Tsp29Fb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - Uvrag anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - atms anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - dbe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - grau anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - gus anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - ihog anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - l(1)G0020 experimental knowledge based (Guruharsha et al., 2011) CG31694 - nop5 experimental knowledge based (Guruharsha et al., 2011) CG31694 - pit experimental knowledge based (Guruharsha et al., 2011) CG31694 - tan anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - vig anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31694 - wee anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG31694 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59712 DroID - A comprehensive database of gene and protein interactions. • FBgn0051694 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33489
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG62FT3C Dipteran inclusive ortholog search EOG6HDT30 Insect inclusive ortholog search EOG6RN95H Arthropod inclusive ortholog search EOG62RBQ8 Metazoa inclusive ortholog search EOG6TJ7NB
Orthologs in Drosophila Species (EOG62FT3C)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG31694     Drosophila simulans   Dsim\GD22793 Y   Drosophila sechellia   Dsec\GM18186 Y   Drosophila erecta   Dere\GG24479 Y   Drosophila yakuba   Dyak\GE14985 Y   Drosophila ananassae   Dana\GF14911 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA16401 Y   Drosophila persimilis   Dper\GL26710 Y   Drosophila willistoni   Dwil\GK24748 Y   Drosophila virilis   Dvir\GJ15385     Drosophila virilis   Dvir\GJ17912 Y   Drosophila mojavensis   Dmoj\GI17570 Y   Drosophila grimshawi   Dgri\GH11052 Y
Orthologs in non-Drosophila Dipterans (EOG6HDT30)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002175   Anopheles gambiae Malaria mosquito  Agam\AGAP001032   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006316
Orthologs in non-Dipteran Insects (EOG6RN95H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC409368   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013452   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15966   Atta cephalotes Leafcutter ant  Acep\ACEP14660   Camponotus floridanus Florida carpenter ant  Cflo\CFLO23232   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15525   Linepithema humile Argentine ant  Lhum\LH14332   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11597   Solenopsis invicta Red fire ant  Sinv\SINV18218   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003475   Bombyx mori Silkmoth  Bmor\BGIBMGA012670   Pediculus humanus Human body louse  Phum\PHUM047060   Tribolium castaneum Red flour beetle  Tcas\TC012308
Orthologs in non-Insect Arthropods (EOG62RBQ8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\COII   Ixodes scapularis Deer tick  Isca\ISCW009369
Orthologs in non-Arthropod Metazoa (EOG6TJ7NB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F58B3.6   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008258gn   Danio rerio Zebrafish  Drer\ifrd1   Xenopus tropicalis Western clawed frog  Xtro\ifrd1   Xenopus tropicalis Western clawed frog  Xtro\ifrd2   Gallus gallus Domestic chicken  Ggal\IFRD1   Mus musculus House mouse  Mmus\Ifrd1   Mus musculus House mouse  Mmus\Ifrd2   Rattus norvegicus Norway rat  Rnor\Ifrd2   Homo sapiens Human  Hsap\IFRD2   Homo sapiens Human  Hsap\IFRD1
Human Orthologs (2)
Gene OMIM HGNC Hsap\IFRD2     Hsap\IFRD1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22793 Drosophila sechellia Dsec\GM18186 Drosophila erecta Dere\GG24479 Drosophila yakuba Dyak\GE14985 Drosophila ananassae Dana\GF14911 Drosophila pseudoobscura pseudoobscura Dpse\GA16401 Drosophila persimilis Dper\GL26710 Drosophila willistoni Dwil\GK24748 Drosophila virilis Dvir\GJ17912 Drosophila mojavensis Dmoj\GI17570 Drosophila grimshawi Dgri\GH11052
Stocks & Reagents
Stocks Listed in FlyBase ( 12 )
Bloomington	20811 y1 w67c23; P{EPgy2}CG31694EY11632 38228 y1 sc* v1; P{TRiP.HMS01672}attP40 13976 y1; P{SUPor-P}CG31694KG04350/CyO; ry506 31004 y1 w*; Mi{MIC}CG31694MI00441 CG8813MI00441/CyO
Harvard	- PBac{PB}CG31694c03550 - PBac{RB}CG31694e03952
Kyoto	123133 w1118; P{RS3}CG31694CB-0337-3 125946 w1118; P{RS5}CG316945-SZ-3215 104743 w*; P{GawB}CG31694NP4693 / TM3, Sb1 Ser1 111577 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{SUPor-P}CG31694KG04350 P{neoFRT}40A/CyO y+
VDRC	v103565 P{KK101281}VIE-260B v21398 w1118; P{GD10333}v21398
Genomic Clones ( 1 )
	BACR42J13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 94 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP04564
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT09520 AT10330 AT11378 AT12203 AT18206 AT18978 AT19115 GH07810 GH14105 GH14511 GH15261 GH15814 GH23443 HL01954 LD07437 LD13282 LD18057 LD36202 LP04865 LP10327 LP10529 LP19820 RE03913 RE06783 RE06994 RE11187 RE15490 RE23057 RE28826 RE32647 RE39672 RE44792 RE46854 RE49234 RE51134 RE52339 RE59787 RE62587 RE68646 RE71872 RE73655 RE73964 RE74761 RH04557 RH04584 RH04965 RH06607 RH07544 RH07727 RH07819 RH19024 RH19153 RH20446 RH23446 RH25958 RH27103 RH27975 RH28383 RH41732 RH64320 SD03078 SD09349 SD16715 SD22909 SD27877
Other clones	100355 104950 AT01056 bs52f03 CK01.15A.E9 Dmel_neb_006090_0632_0340 Dmel_neb_014516_0918_3499 EC22219 EC22455 EC22536 EC053775 EK095407 EK100017 EK136039 EK186456 EK213045 EK217528 EK222960 EK229664 EK235523 EK237851 EK260016 EK262126 EK291626 EK302727 FGC018H06 FGH101A03 RE01012
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0051694 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33489
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG15401 CG3098 (FlyBase Genome Annotators, 2002-2003)
Additional comments	Annotations CG15401 and CG3098 merged as CG31694 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_164511 RefSeq (Proteins) • NP_722858 DDBJ / EMBL / GenBank • AAF51186 AAM50876 AI260630 AY119016 BH809461 CL943503 CZ468711 CZ468712 CZ481712 Entrez Gene - A searchable database of RefSeq genes. • 33489 UniProtKB/TrEMBL • Q9VQI5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Interferon-related developmental regulator, C-terminal (IPR006921) Interferon-related developmental regulator, N-terminal (IPR007701) Armadillo-type fold (IPR016024) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LP04564
Linkouts
	BioGRID - A database of protein and genetic interactions • 59712 DroID - A comprehensive database of gene and protein interactions. • FBgn0051694 DRSC - Results from RNAi screens. • FBgn0051694 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051694 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31694-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0051694 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33489 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33489 modMine - Data generated by the modENCODE project. • FBgn0051694
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG3098 (Robertson, 2001.7.7, ) CG15401 (Robertson, 2001.7.7, ) CG31694 (Buszczak et al., 2007, Quinones-Coello, 2007, Keleman et al., 2009.8.5, Liebl and Featherstone, 2005, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2010.12.1)
Name Synonym
Secondary FlyBase IDs
	FBgn0031475 FBgn0031477
References ( 30 )
Generate a list of	All references relating to this gene ( 30 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...