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Gene Dmel\CG31717

General Information
Symbol	Dmel\CG31717	Species	D. melanogaster
Name		Annotation symbol	CG31717
Feature type	protein_coding_gene	FlyBase ID	FBgn0051717
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	31B1-31B1	Sequence location	2L:10,250,737..10,251,714 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG31717 (FBgn0051717). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: catalytic activity. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase; Phosphatidic acid phosphatase/chloroperoxidase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625710_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG31717. Gene sequence location is 2L:10250737..10251714.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 31B1-31B1   Limits computationally determined from genome sequence between P{lacW}me31Bk06607 and P{PZ}nmd08774
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG31717 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG31717-RA FBtr0079977  NM_164902   790   204 CG31717-RB FBtr0333409  NM_001273388   854   204
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG31717-PA   FBpp0079567   23.0   204   9.52     NP_723543   AAN10729 CG31717-PB   FBpp0305601   23.0   204   9.52     NP_001260317   AGB92852
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326) Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (IPR016118)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAN10729   AE014134 AGB92852   AY075278 AAL68145   BG634055   BI353494   BI366664   BP548178   BP558378   BP558379   BQ102797   CA804783   CK661588   CO155532   CO183321   CO278554   CO321106   CO340568   EC198677   EC235858   EC250927   EC254526
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8T8T9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut  (578.4) Larval Hindgut    297.9 Larval Malpighian Tubules  (966.5) Larval Fat Body  (677.2) Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut  578.4 Larval Hindgut    297.9 Larval Malpighian Tubules  (966.5) Larval Fat Body  677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    163.95 Larval Midgut    578.4 Larval Hindgut    297.9 Larval Malpighian Tubules    966.5 Larval Fat Body    677.2 Larval Salivary Gland    369.9 Larval Trachea    290.8 Larval Carcass    253.525 Adult Head    250.4 Adult Eye    283.6 Adult Brain    186.2 Adult Thoracic-Abdominal Ganglion    202.8 Adult Crop    234.5 Adult Midgut    424 Adult Hindgut    269.5 Adult Malpighian Tubules    313.9 Adult Fat Body    299.5 Adult Salivary Gland    424.4 Adult Heart    427.15 Adult VirginFemale Spermatheca    207.4 Adult InseminatedFemale Spermatheca    230.6 Adult Ovary    181.6 Adult Testis    184.5 Adult Male Accessory Gland    245.2 Adult Carcass    311.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    250.4   NA  Eye    283.6   NA  Brain    186.2   163.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    202.8   NA  Crop    234.5   578.4  Midgut    424   297.9  Hindgut    269.5   966.5  Malpighian Tubules    313.9   677.2  Fat Body    299.5   369.9  Salivary Gland    424.4   NA  Heart    427.15   290.8  Trachea    NA   NA  VirginFemale Spermatheca    207.4   NA  InseminatedFemale Spermatheca    230.6   NA  Ovary    181.6   NA  Testis    184.5   NA  Male Accessory Gland    245.2   253.525  Carcass    311.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering  (48) salivary gland, white prepupae  (40) digestive system, larvae L3 wandering  (75) digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae  26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male  (43) accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering  (48) salivary gland, white prepupae  (40) digestive system, larvae L3 wandering  (75) digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae  26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male  (43) accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    19 central nervous system, larvae L3    12 central nervous system, pupae P8    12 head, virgin 1-day female    8 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    10 head, mated 4-day female    11 head, mated 20-day female    9 head, mated 1-day male    9 head, mated 4-day male    14 head, mated 20-day male    17 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    40 digestive system, larvae L3 wandering    75 digestive system, 1-day adult    22 digestive system, 4-day adult    17 digestive system, 20-day adult    15 fat body, larvae L3 wandering    8 fat body, white prepupae    26 fat body, pupae P8    23 carcass, larvae L3 wandering    21 carcass, 1-day adult    9 carcass, 4-day adult    8 carcass, 20-day adult    13 ovary, virgin 4-day female    20 ovary, mated 4-day female    15 testis, mated 4-day male    43 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9    118 white prepupae new    126 white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr  (39) embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2  (38) larva L3 puffstage 3-6  (60) larva L3 puffstage 7-9  (118) white prepupae new  (126) white prepupae 12hr  (40) white prepupae 24hr  (29) pupae 2d postWPP  (27) pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day  26 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9  (118) white prepupae new  (126) white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9    118 white prepupae new    126 white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9    118 white prepupae new    126 white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr  (39) embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2  (38) larva L3 puffstage 3-6  (60) larva L3 puffstage 7-9  (118) white prepupae new  (126) white prepupae 12hr  (40) white prepupae 24hr  29 pupae 2d postWPP  27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day  26 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9  118 white prepupae new  126 white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    26 embryo 02-04hr    20 embryo 04-06hr    19 embryo 06-08hr    23 embryo 08-10hr    25 embryo 10-12hr    39 embryo 12-14hr    23 embryo 14-16hr    13 embryo 16-18hr    14 embryo 18-20hr    12 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    13 larva L2    17 larva L3 12hr old    22 larva L3 puffstage 1-2    38 larva L3 puffstage 3-6    60 larva L3 puffstage 7-9    118 white prepupae new    126 white prepupae 12hr    40 white prepupae 24hr    29 pupae 2d postWPP    27 pupae 3d postWPP    22 pupae 4d postWPP    19 adult male 01day    23 adult male 05day    25 adult male 30day    20 adult female 01day    19 adult female 05day    25 adult female 30day    26 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    133 Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (133) Schneider line 2 Sg4  (69) embryonic 1182-4H    22 embryonic GM2  (33) embryonic Kc167  (45) embryonic S1  (44) embryonic S3  (62) leg disc CME L1    23 wing disc CME-W2  (59) wing disc ML-DmD8  26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21  (51) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  (40) eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5  (66) mixed discs ML-DmD4-c1  (60) CNS ML-DmBG1-c1  (34) CNS ML-DmBG2-c2  (104) tumorous blood cells mbn2  (84) ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (133) Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2  104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    133 Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    133 Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (133) Schneider line 2 Sg4  (69) embryonic 1182-4H    22 embryonic GM2  (33) embryonic Kc167  (45) embryonic S1  (44) embryonic S3  (62) leg disc CME L1    23 wing disc CME-W2  (59) wing disc ML-DmD8  26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21  (51) wing disc ML-DmD32    25 haltere disc ML-DmD17-c3  (40) eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5  (66) mixed discs ML-DmD4-c1  (60) CNS ML-DmBG1-c1  (34) CNS ML-DmBG2-c2  (104) tumorous blood cells mbn2  (84) ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  133 Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2  104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    133 Schneider line 2 Sg4    69 embryonic 1182-4H    22 embryonic GM2    33 embryonic Kc167    45 embryonic S1    44 embryonic S3    62 leg disc CME L1    23 wing disc CME-W2    59 wing disc ML-DmD8    26 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    51 wing disc ML-DmD32    25 haltere disc ML-DmD17-c3    40 eye-antennal disc ML-DmD11    20 antennal disc ML-DmD20-c5    66 mixed discs ML-DmD4-c1    60 CNS ML-DmBG1-c1    34 CNS ML-DmBG2-c2    104 tumorous blood cells mbn2    84 ovary fGS/OSS    7 ovary OSC    12 ovary OSS    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3  (31) Cadmium 50 mM 12 hrs, larvae L3  (58) Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3  (38) Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (31) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3  (41) Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3  31 Cadmium 50 mM 12 hrs, larvae L3  (58) Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3  (38) Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3  31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3  (41) Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    8 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    58 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    15 Ethanol 5% 3 hrs, larvae L3    38 Ethanol 10% 3 hrs, larvae L3    23 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    41 Rotenone 8 μg 12 hrs, larvae L3    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051717 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31717-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG31717GD1057 partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 CG31717GD1057 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG31717GD1057 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG31717GD1057
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG31717 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG31717 Class Mutagen Stocks Known lesion CG31717GD1057 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG31717KK100234 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG31717NIG.31717R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6026 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD1057} NA P{KK100234} NA P{NIG.31717R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
catalytic activity inferred from electronic annotation with InterPro:IPR000326, InterPro:IPR016118 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
membrane inferred from electronic annotation with InterPro:IPR000326 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG31717 - CG10934 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG31717 - hoe1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG31717 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0051717
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG64MZCG Dipteran inclusive ortholog search EOG6K6GDB Insect inclusive ortholog search EOG63FFTJ Arthropod inclusive ortholog search EOG64XH0D Metazoa inclusive ortholog search EOG6Z6FHV
Orthologs in Drosophila Species (EOG64MZCG)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG31717     Drosophila simulans   Dsim\GD23668 Y   Drosophila sechellia   Dsec\GM18048 Y   Drosophila erecta   Dere\GG10096 Y   Drosophila yakuba   Dyak\GE18910 Y   Drosophila ananassae   Dana\GF15755 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA16419 Y   Drosophila persimilis   Dper\GL19163 Y   Drosophila willistoni   Dwil\GK19233 Y   Drosophila virilis   Dvir\GJ18120 Y   Drosophila mojavensis   Dmoj\GI17619 Y   Drosophila grimshawi   Dgri\GH13360 Y
Orthologs in non-Drosophila Dipterans (EOG6K6GDB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008674   Anopheles gambiae Malaria mosquito  Agam\AGAP005824   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ002087
Orthologs in non-Dipteran Insects (EOG63FFTJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB49624   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000444   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21442   Atta cephalotes Leafcutter ant  Acep\ACEP25235   Camponotus floridanus Florida carpenter ant  Cflo\CFLO12971   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14449   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18732   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15716   Linepithema humile Argentine ant  Lhum\LH16565   Linepithema humile Argentine ant  Lhum\LH24570   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20825   Solenopsis invicta Red fire ant  Sinv\SINV13587   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008190   Bombyx mori Silkmoth  Bmor\BGIBMGA003339   Bombyx mori Silkmoth  Bmor\BGIBMGA003340   Pediculus humanus Human body louse  Phum\PHUM425010   Tribolium castaneum Red flour beetle  Tcas\TC003248
Orthologs in non-Insect Arthropods (EOG64XH0D)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\COI   Daphnia pulex Water flea  Dpux\JGI_V11_231013   Ixodes scapularis Deer tick  Isca\ISCW013935   Ixodes scapularis Deer tick  Isca\ISCW013934
Orthologs in non-Arthropod Metazoa (EOG6Z6FHV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Danio rerio Zebrafish  Drer\ENSDARG00000052033
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23668 Drosophila sechellia Dsec\GM18048 Drosophila erecta Dere\GG10096 Drosophila yakuba Dyak\GE18910 Drosophila ananassae Dana\GF15755 Drosophila pseudoobscura pseudoobscura Dpse\GA16419 Drosophila persimilis Dper\GL19163 Drosophila willistoni Dwil\GK19233 Drosophila virilis Dvir\GJ18120 Drosophila mojavensis Dmoj\GI17619 Drosophila grimshawi Dgri\GH13360
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v105379 P{KK100234}VIE-260B v7662 w1118; P{GD1057}v7662 v7663 w1118; P{GD1057}v7663
Genomic Clones ( 2 )
	BACR07H08 BACR30M19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 17 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT30094
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM23882 LP21188 RE52251
Other clones	17760 75311 211010 EC25458 EC254526 EK130351 EK290325 EN06251 EP10915 ESG0115a.B21_H09 FGH124H01 FGM314F04 UUGC0184
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0051717 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318911
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG31717 BcDNA:AT30094 (FlyBase, 1996-)
Additional comments	Source for merge of CG31717 BcDNA:AT30094 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
	New annotation (CG31717) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_164902 NM_001273388 RefSeq (Proteins) • NP_723543 NP_001260317 DDBJ / EMBL / GenBank • AAL68145 AAN10729 AGB92852 AY075278 BG634055 Entrez Gene - A searchable database of RefSeq genes. • 318911 UniProtKB/TrEMBL • Q8T8T9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidic acid phosphatase type 2/haloperoxidase (IPR000326) Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (IPR016118)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0051717 DRSC - Results from RNAi screens. • FBgn0051717 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051717 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG31717-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0051717 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318911 modMine - Data generated by the modENCODE project. • FBgn0051717
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BcDNA:AT30094   CG31717 (Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21) Css2 (Huitema et al., 2004)
Name Synonym
Secondary FlyBase IDs
	FBgn0061440
References ( 14 )
Research paper	Huitema et al., 2004, EMBO J. 23(1): 33--44 Identification of a family of animal sphingomyelin synthases. [FBrf0179030]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2004, Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. [FBrf0166453] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]