dTrim9, asap
Please see the JBrowse view of Dmel\Trim9 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
None of the polypeptides share 100% sequence identity.
Interacts (via fibronectin type-III domain) with pico. Interacts (via SPRY domain) with netrin receptor fra.
The fibronectin type-III, SPRY and coil-coil domains are necessary for C4da axon patterning.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Trim9 using the Feature Mapper tool.
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as ventral nerve cord anlage
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Trim9 is expressed predominantly in the nervous system. It is first detected in PNS neurons in stage 13-14 embryos and persists in later embryonic stages. It is detected in a a subset of neurons including class IV dendritic arborizing (C4da) neurons. Expression is stronger in ddaC and vdaB neurons than in v'ada neurons.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Trim9 in GBrowse 22-43
2-36.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Trim9 CG31721
Source for merge of: CG13145 CG6256
Annotations CG13145 and CG6256 merged as CG31721 in release 3 of the genome annotation.
Source for identity of Trim9 CG31721 was sequence comparison ( date:030807 ).
Trim9 functions cell autonomously in midline guidance.
One of 42 Drosophila genes identified as being most likely to reveal molecular and cellular mechanisms of nervous system development or plasticity relevant to human Mental Retardation disorders.