Gene Dmel\CG31860

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General Information

Symbol

Dmel\CG31860

Species

D. melanogaster

Name

Annotation symbol

CG31860

Feature type

protein_coding_gene

FlyBase ID

FBgn0051860

Gene Model Status

Current

Stock availability

4 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

33D2-33D2

Sequence location

2L:12,164,241..12,166,704 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG31860 (FBgn0051860). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: zinc ion transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process: zinc ion transport. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Cation efflux protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1628612_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG31860. Gene sequence location is 2L:12164241..12166704.

User Contributed Data

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Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

33D2-33D2

Limits computationally determined from genome sequence between P{PZ}Rab6⁰⁸³²³ and P{EP}Elf^EP476&P{EP}bun^EP488

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG31860 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG31860-RB

FBtr0302984

NM_164998

2257

701

CG31860-RC

FBtr0302985

NM_001201864

2264

436

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG31860-PB

FBpp0292109

78.1

701

7.23

NP_723732

AAF53175

CG31860-PC

FBpp0292110

48.7

436

7.43

NP_001188793

ADV37043

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Cation efflux protein (IPR002524)

Cation efflux protein transmembrane domain (IPR027469)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VKA3

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1.575
Larval Midgut		8.4
Larval Hindgut		6.2
Larval Malpighian Tubules		4.8
Larval Fat Body		38.9
Larval Salivary Gland		5.2
Larval Trachea		6.025
Larval Carcass		7.35
Adult Head		7
Adult Eye		2.5
Adult Brain		4.7
Adult Thoracic-Abdominal Ganglion		10.2
Adult Crop		6.6
Adult Midgut		9.3
Adult Hindgut		9.3
Adult Malpighian Tubules		3.4
Adult Fat Body		9.7
Adult Salivary Gland		10.6
Adult Heart		1.775
Adult VirginFemale Spermatheca		4.9
Adult InseminatedFemale Spermatheca		5.4
Adult Ovary		3
Adult Testis		147.3
Adult Male Accessory Gland		17.3
Adult Carcass		10.2
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	7
NA	Eye	2.5
NA	Brain	4.7
1.575	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	no informative data
NA	Crop	6.6
8.4	Midgut	9.3
6.2	Hindgut	9.3
4.8	Malpighian Tubules	3.4
no informative data	Fat Body	9.7
5.2	Salivary Gland	no informative data
NA	Heart	1.775
6.025	Trachea	NA
NA	VirginFemale Spermatheca	4.9
NA	InseminatedFemale Spermatheca	5.4
NA	Ovary	3
NA	Testis	147.3
NA	Male Accessory Gland	no informative data
7.35	Carcass	no informative data

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		9
central nervous system, larvae L3		0
central nervous system, pupae P8		1
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		3
fat body, pupae P8		4
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		16
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		0
embryo 14-16hr		0
embryo 16-18hr		0
embryo 18-20hr		0
embryo 20-22hr		0
embryo 22-24hr		0
larva L1		0
larva L2		0
larva L3 12hr old		0
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		5
pupae 2d postWPP		7
pupae 3d postWPP		7
pupae 4d postWPP		4
adult male 01day		10
adult male 05day		11
adult male 30day		9
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		3
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		8
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		12
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		1
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(Graveley et al., 2011)

mE1_20_mRNA_expression_cluster_20

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0051860

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG31860-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

CG31860^GD1098

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG31860	Class	Mutagen	Stocks	Known lesion
CG31860^MB08990			1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG31860	Mutagen	Stocks	Known lesion
CG31860^GD1098	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG31860^HMS01776	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG31860^KK100432	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel6032

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD1098}

P{KK100432}

P{TRiP.HMS01776}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap binary system

Mi{ET1}CG31760^MB08990

Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 4 terms )

Molecular Function

CV term

Evidence

References

zinc ion transmembrane transporter activity

inferred from sequence or structural similarity with UniProtKB:Q62941

(FlyBase Genome Annotators, 2002-2003)

Biological Process

CV term

Evidence

References

transmembrane transport

inferred from electronic annotation with InterPro:IPR002524

(FlyBase Curators et al., 2004-)

zinc ion transport

inferred from sequence or structural similarity with UniProtKB:Q62941

(FlyBase Genome Annotators, 2002-2003)

Cellular Component

CV term

Evidence

References

integral to membrane

inferred from electronic annotation with InterPro:IPR002524

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG31860 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0051860

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

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326167

Orthologs

OrthoDB Orthologs (48) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6BG9G8

Dipteran inclusive ortholog search

EOG64J2ST

Insect inclusive ortholog search

EOG6JM6K7

Arthropod inclusive ortholog search

EOG6NP5K2

Metazoa inclusive ortholog search

EOG6Z99Q3

Orthologs in Drosophila Species (EOG6BG9G8)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\CG31860

Drosophila pseudoobscura pseudoobscura

Dpse\GA16530

Drosophila willistoni

Dwil\GK19068

Orthologs in non-Drosophila Dipterans (EOG64J2ST)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL011256

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008693

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL001239

Anopheles gambiae

Malaria mosquito

Agam\AGAP009005

Anopheles gambiae

Malaria mosquito

Agam\AGAP008982

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ002493

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ010101

Orthologs in non-Dipteran Insects (EOG6JM6K7)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\Ame.7852

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG002069

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH20113

Atta cephalotes

Leafcutter ant

Acep\ACEP28000

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL23836

Linepithema humile

Argentine ant

Lhum\LH15061

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB22163

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI008732

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI085119

Bombyx mori

Silkmoth

Bmor\BGIBMGA005779

Pediculus humanus

Human body louse

Phum\PHUM503490

Tribolium castaneum

Red flour beetle

Tcas\TC004740

Orthologs in non-Insect Arthropods (EOG6NP5K2)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_191209

Orthologs in non-Arthropod Metazoa (EOG6Z99Q3)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\cdf-2

Caenorhabditis elegans

Nematode

Cele\ttm-1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_021020gn

Danio rerio

Zebrafish

Drer\slc30a4

Danio rerio

Zebrafish

Drer\slc30a2

Danio rerio

Zebrafish

Drer\slc30a8

Xenopus tropicalis

Western clawed frog

Xtro\slc30a2

Xenopus tropicalis

Western clawed frog

Xtro\slc30a8

Xenopus tropicalis

Western clawed frog

Xtro\slc30a4

Xenopus tropicalis

Western clawed frog

Xtro\slc30a3

Gallus gallus

Domestic chicken

Ggal\SLC30A8

Gallus gallus

Domestic chicken

Ggal\LOC772039

Gallus gallus

Domestic chicken

Ggal\LOC776399

Mus musculus

House mouse

Mmus\Slc30a4

Mus musculus

House mouse

Mmus\Slc30a8

Mus musculus

House mouse

Mmus\Slc30a3

Mus musculus

House mouse

Mmus\Slc30a2

Rattus norvegicus

Norway rat

Rnor\Slc30a2

Rattus norvegicus

Norway rat

Rnor\Slc30a4

Rattus norvegicus

Norway rat

Rnor\Slc30a8

Rattus norvegicus

Norway rat

Rnor\Slc30a3

Homo sapiens

Human

Hsap\ENSG00000164756

Homo sapiens

Human

Hsap\SLC30A2

Homo sapiens

Human

Hsap\SLC30A3

Homo sapiens

Human

Hsap\SLC30A4

Human Orthologs (4)

Gene

OMIM

HGNC

AAA Orthologs (1) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila grimshawi

Dgri\GH10561

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Bloomington

38312

y¹ sc^* v¹; P{TRiP.HMS01776}attP40

26425

w¹¹¹⁸; Mi{ET1}CG31760^MB08990 CG31860^MB08990

VDRC

v103398

P{KK100432}VIE-260B

v7688

w¹¹¹⁸; P{GD1098}v7688

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 5 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

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FBgn0051860

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

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326167

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Annotation CG17215 split into CG31860, CG31861 and CG31760 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

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RefSeq (Proteins)

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DDBJ / EMBL / GenBank

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Entrez Gene - A searchable database of RefSeq genes.

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326167

UniProtKB/TrEMBL

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Q9VKA3

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

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Cation efflux protein (IPR002524)

Cation efflux protein transmembrane domain (IPR027469)

Linkouts

DroID - A comprehensive database of gene and protein interactions.

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FBgn0051860

DRSC - Results from RNAi screens.

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FBgn0051860

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

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FBgn0051860

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

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CG31860-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0051860

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

326167

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

326167

modMine - Data generated by the modENCODE project.

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FBgn0051860

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG17215

(Brody and Cravchik, 2000, )

CG31860

(Wang et al., 2009, Keleman et al., 2009.8.5, Ni et al., 2010.12.1)

Name Synonym

Secondary FlyBase IDs

FBgn0032418

References ( 14 )

Research paper

Lye et al., 2013, J. Biol. Inorg. Chem. 18(3): 323--332: In vivo zinc toxicity phenotypes provide a sensitized background that suggests zinc transport activities for most of the Drosophila Zip and ZnT genes. [FBrf0220942]
Wang et al., 2009, FASEB J. 23(8): 2650--2661: Dietary zinc absorption is mediated by ZnT1 in Drosophila melanogaster. [FBrf0208447]
Brody and Cravchik, 2000, J. Cell Biol. 150(2): F83--F88: Drosophila melanogaster G Protein-coupled Receptors. [FBrf0129744]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]

Personal communication to FlyBase

Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila.: A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Bellen, 2008.12.12, set821.xml: set821.xml [FBrf0206287]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]

FlyBase analysis

FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]

Curated genome annotation

FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.]: [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]
Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126677]