DMRTF, mal-d, mal
Gene model reviewed during 5.54
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 6.02
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mrtf using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Mrtf in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Mrtf CG32296
Source for merge of: CG12188 CG14951
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Mrtf is required for proper patterning of the tracheal system, for mesodermal cell migration and for the formation of wing intervein tissue.
A substantial open reading frame is present upstream of the ATG codon, but its significance is unclear. There is strong in vivo evidence that the physical state of the cell determines whether Mrtf protein accumulates in the nucleus; slbo mutant border follicle cells, which cannot on their own accumulate nuclear Mrtf protein, can accumulate nuclear Mrtf protein if they are pulled by wild-type cells.