General Information Symbol Dmel\ ltlSpecies D. melanogaster Name larval translucida Annotation symbol CG32372 Feature type protein_coding_gene FlyBase ID FBgn0052372 Gene Model Status Current Stock availability 6 publicly
available Genomic Location Chromosome (arm) 3L Recombination map Cytogenetic map 66A3-66A4 Sequence location 3L:7,512,097..7,521,113 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
larval translucida is referred to in FlyBase by the symbol
Dmel\ltl (CG32372, FBgn0052372). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. There is experimental evidence that it is involved in the
biological process : imaginal disc-derived wing vein specification; imaginal disc-derived wing morphogenesis.
17 alleles are reported . The
phenotypes of these alleles are annotated with: larva; posterior crossvein; anterior crossvein; wing. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Leucine rich repeat 5; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult heart, larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, larval hindgut, adult fat body, adult spermathecae, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633286_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG32372. Gene sequence location is
3L:7512097..7521113 .
User Contributed Data
Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release.
It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your
feed reader .
FB2013_03
FB2013_02
All updates
Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.45
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. regulatory region
evidence=Reporter construct (in vivo)
External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Additional Descriptive Data
Transcripts are expressed in ventral cells of the blastoderm embryo. The posterior border coincides with the posterior limit of the ventral furrow. Anteriorly, expression extends up to the anterior pole. The expression is graded with the peak at the anterior end of the embryo. During germ band extension, expression is strong in the head and much weaker in the invaginated mesoderm. In late stages of germ band extension, new expression occurs in the mesoderm in a segmentally repeated pattern. In late embryos, expression is observed in the fat body.
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
2489.675
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
(892.2)
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
(2489.675)
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
(2489.675)
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
2489.675
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
2489.675
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
(892.2)
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
(2489.675)
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
(2489.675)
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
229.15
Larval Midgut
37.6
Larval Hindgut
144.7
Larval Malpighian Tubules
31.5
Larval Fat Body
511.2
Larval Salivary Gland
9.3
Larval Trachea
41.75
Larval Carcass
142.75
Adult Head
388.1
Adult Eye
892.2
Adult Brain
241.2
Adult Thoracic-Abdominal Ganglion
281.7
Adult Crop
10.9
Adult Midgut
2.7
Adult Hindgut
20.3
Adult Malpighian Tubules
6.5
Adult Fat Body
451.5
Adult Salivary Gland
5
Adult Heart
2489.675
Adult VirginFemale Spermatheca
201.4
Adult InseminatedFemale Spermatheca
294.3
Adult Ovary
0.7
Adult Testis
8
Adult Male Accessory Gland
22.8
Adult Carcass
182.2
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
388.1
NA
Eye
892.2
NA
Brain
241.2
229.15
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
281.7
NA
Crop
10.9
37.6
Midgut
2.7
144.7
Hindgut
20.3
31.5
Malpighian Tubules
6.5
511.2
Fat Body
451.5
9.3
Salivary Gland
5
NA
Heart
2489.675
41.75
Trachea
NA
NA
VirginFemale Spermatheca
201.4
NA
InseminatedFemale Spermatheca
294.3
NA
Ovary
0.7
NA
Testis
8
NA
Male Accessory Gland
22.8
142.75
Carcass
182.2
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
(63)
head, virgin 4-day female
(71)
head, virgin 20-day female
(51)
head, mated 1-day female
(78)
head, mated 4-day female
(59)
head, mated 20-day female
(53)
head, mated 1-day male
(98)
head, mated 4-day male
(102)
head, mated 20-day male
(92)
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
(58)
fat body, white prepupae
(36)
fat body, pupae P8
(37)
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
(30)
carcass, 20-day adult
(31)
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
(63)
head, virgin 4-day female
(71)
head, virgin 20-day female
(51)
head, mated 1-day female
(78)
head, mated 4-day female
(59)
head, mated 20-day female
(53)
head, mated 1-day male
(98)
head, mated 4-day male
(102)
head, mated 20-day male
(92)
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
(58)
fat body, white prepupae
(36)
fat body, pupae P8
(37)
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
11
central nervous system, larvae L3
21
central nervous system, pupae P8
22
head, virgin 1-day female
63
head, virgin 4-day female
71
head, virgin 20-day female
51
head, mated 1-day female
78
head, mated 4-day female
59
head, mated 20-day female
53
head, mated 1-day male
98
head, mated 4-day male
102
head, mated 20-day male
92
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
4
digestive system, larvae L3 wandering
14
digestive system, 1-day adult
1
digestive system, 4-day adult
2
digestive system, 20-day adult
1
fat body, larvae L3 wandering
58
fat body, white prepupae
36
fat body, pupae P8
37
carcass, larvae L3 wandering
18
carcass, 1-day adult
26
carcass, 4-day adult
30
carcass, 20-day adult
31
ovary, virgin 4-day female
0
ovary, mated 4-day female
0
testis, mated 4-day male
1
accessory gland, mated 4-day male
3
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
(31)
embryo 06-08hr
26
embryo 08-10hr
(29)
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
19
embryo 04-06hr
31
embryo 06-08hr
26
embryo 08-10hr
29
embryo 10-12hr
18
embryo 12-14hr
15
embryo 14-16hr
11
embryo 16-18hr
10
embryo 18-20hr
10
embryo 20-22hr
10
embryo 22-24hr
16
larva L1
12
larva L2
10
larva L3 12hr old
8
larva L3 puffstage 1-2
9
larva L3 puffstage 3-6
17
larva L3 puffstage 7-9
23
white prepupae new
16
white prepupae 12hr
16
white prepupae 24hr
22
pupae 2d postWPP
9
pupae 3d postWPP
7
pupae 4d postWPP
10
adult male 01day
17
adult male 05day
18
adult male 30day
16
adult female 01day
8
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
(55)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
(55)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
0
Schneider line 2 Sg4
0
embryonic 1182-4H
0
embryonic GM2
0
embryonic Kc167
0
embryonic S1
0
embryonic S3
0
leg disc CME L1
0
wing disc CME-W2
1
wing disc ML-DmD8
0
wing disc ML-DmD9
0
wing disc ML-DmD16-c3
0
wing disc ML-DmD21
0
wing disc ML-DmD32
0
haltere disc ML-DmD17-c3
0
eye-antennal disc ML-DmD11
0
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
1
CNS ML-DmBG1-c1
2
CNS ML-DmBG2-c2
1
tumorous blood cells mbn2
0
ovary fGS/OSS
1
ovary OSC
17
ovary OSS
55
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
(28)
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
(32)
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
16
cold shock, 4-day adult
13
heat shock, 4-day adult
10
Cadmium 50 mM 6 hrs, larvae L3
9
Cadmium 50 mM 12 hrs, larvae L3
10
Cadmium 50 mM 48 hrs, 4-day adult
14
Cadmium 100 mM 48 hrs, 4-day adult
13
Copper 0.5 mM 12 hrs, larvae L3
12
Copper 15 mM 48 hrs, 4-day adult
20
Zinc 5 mM 12 hrs, larvae L3
20
Zinc 4.5 mM 48 hrs, 4-day adult
28
Ethanol 2.5% 3 hrs, larvae L3
9
Ethanol 5% 3 hrs, larvae L3
14
Ethanol 10% 3 hrs, larvae L3
12
Caffeine 1.5 mg/ml 4 hrs, larvae L3
13
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
21
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
14
Paraquat 10 mM 48 hrs, 4-day adult
32
Rotenone 2 μg 12 hrs, larvae L3
9
Rotenone 8 μg 12 hrs, larvae L3
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 9 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 8 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms ) Terms Based on
Experimental Evidence ( 3 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component inferred from direct assay
Terms Based on Predictions or
Assertions ( 0 terms ) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti bait coimmunoprecipitation, western blot
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (29)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG65MNQS )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6C5CSR )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6WSV5S )
Apis mellifera
Western honey bee
Amel\LOC408888
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG017764
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH15394
Atta cephalotes
Leafcutter ant
Acep\ACEP16810
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO20633
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL19642
Linepithema humile
Argentine ant
Lhum\LH24215
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB11833
Solenopsis invicta
Red fire ant
Sinv\SINV17395
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG622810 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 6 )Bloomington Harvard VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 42 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology The gene is named "larval translucida" based on the translucent, edemic appearance of mutant larvae.
Identification Relationship to Other Genes Source for database identity of Source for identity of: ltl CG32372
Source for database merge of Source for merge of: CG14836 CG7545
Source for merge of: CG32372 anon-EST:CL1a11
Additional comments Annotations CG14836 and CG7545 merged as CG32372 in release 3 of the genome annotation.
Source for merge of CG32372 anon-EST:CL1a11 was sequence comparison (date:030620).
Other Comments ChEST reveals this is a target of
Mef2 .
Identification: isolated from a subtractive cDNA library enriched in sequences expressed in the mesoderm.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
- A database of transcriptional regulatory elements.
Synonyms & Secondary IDs
( 8 )Reported As Symbol Synonym CG32372
(
Szuperák et al., 2011 ,
Biemar et al., 2006 ,
Han et al., 2006 ,
Sandmann et al., 2007 ,
Hueber et al., 2007 ,
Junion et al., 2007 ,
Hazelett et al., 2012 ,
Perkins et al., 2009 ,
Tomancak et al., 2007 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Secondary FlyBase
IDs FBgn0019866 FBgn0035794 FBgn0040836 References ( 34 )Generate a list of List References by type
Recent research papers ( 3 )
Hazelett et al., 2012, G3 (Bethesda) 2(7): 789--802Comparison of Parallel High-Throughput RNA Sequencing Between Knockout of TDP-43 and Its Overexpression Reveals Primarily Nonreciprocal and Nonoverlapping Gene Expression Changes in the Central Nervous System of Drosophila. [FBrf0219102] Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Szuperák et al., 2011, Development 138(4): 715--724Feedback regulation of Drosophila BMP signaling by the novel extracellular protein Larval Translucida. [FBrf0212881]