a component of the tripartite IPP complex that maintains the integrin-actin link at embryonic muscle attachment sites - affects the organization of actin cytoskeleton in both wing and eye epithelia
Please see the JBrowse view of Dmel\parvin for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.55
Gene model reviewed during 5.45
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\parvin using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
parvin is detected in stage 13 embryos at low levels in the leading edge epidermal cells during dorsal closure. In later stages, it is expressed mainly in mesoderm-derived tissues, including visceral mesoderm, somatice muscles and pharyngeal muscles. From stage 14 on, it is observed at muscle attachment sites.
JBrowse - Visual display of RNA-Seq signals
View Dmel\parvin in JBrowse1-64
1-62.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Annotation CG12533 split into CG32530 and CG32528 in release 3 of the genome annotation.
Source for identity of: parvin CG32528