FB2019_05, released Oct 15, 2019

Gene: Dmel\parvin

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General Information
Symbol
Dmel\parvin
Species
D. melanogaster
Name
parvin
Annotation Symbol
CG32528
Feature Type
protein_coding_gene
FlyBase ID
FBgn0052528
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Snapshot
parvin (parvin) encodes a Calponin-homology protein that, together with the products of Ilk and stck, reinforces integrin-matrix adhesion at muscle attachment sites in the developing embryo. The product of parvin contributes to cell adhesion and actin cytoskeleton organisation in muscles, wing and eye epithelial cells. [Date last reviewed: 2019-03-14]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
18E5-18F1
Sequence location
X:19,746,041..19,748,458 [+]
Recombination map
1-64
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Molecular Function (GO)
[Detailed GO annotations]
Experimental Evidence
-
Predictions / Assertions
actin binding
Summaries
Summary (Interactive Fly)
a component of the tripartite IPP complex that maintains the integrin-actin link at embryonic muscle attachment sites - affects the organization of actin cytoskeleton in both wing and eye epithelia
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the GBrowse view of Dmel\parvin or the JBrowse view of Dmel\parvin for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.55
Gene model reviewed during 5.45
Gene model reviewed during 5.56
Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
(Vakaloglou et al., 2007)
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
parvin-RA
FBtr0074793
NM_134508
1801
367
parvin-RB
FBtr0346042
NM_001298535
1840
367
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
parvin-PA
FBpp0074562
41.9
367
6.58
NP_608352
AAF49016
parvin-PB
FBpp0311906
41.9
367
6.58
NP_001285464
AHN59934
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

367 aa isoforms: parvin-PA, parvin-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\parvin using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Gene Ontology (10 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
actin binding
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (6 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
apposition of dorsal and ventral imaginal disc-derived wing surfaces
inferred from mutant phenotype
(Vakaloglou et al., 2012)
muscle attachment
inferred from mutant phenotype
(Vakaloglou et al., 2012)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
actin cytoskeleton reorganization
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
cell projection assembly
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
establishment or maintenance of cell polarity
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
substrate adhesion-dependent cell spreading
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
focal adhesion
inferred from direct assay
(Vakaloglou et al., 2012)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
actin cytoskeleton
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
focal adhesion
inferred from biological aspect of ancestor with PANTHER:PTN000950308
(assigned by GO_Central )
(Gaudet et al., 2011)
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 13
embryonic dorsal epidermis
(Vakaloglou et al., 2012)
embryonic stage 13 -- 16
embryonic/larval somatic muscle
(Vakaloglou et al., 2012)
visceral mesoderm
(Vakaloglou et al., 2012)
embryonic stage 14 -- 16
pharyngeal muscle
(Vakaloglou et al., 2012)
muscle attachment site
(Vakaloglou et al., 2012)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
parvin is detected in stage 13 embryos at low levels in the leading edge epidermal cells during dorsal closure. In later stages, it is expressed mainly in mesoderm-derived tissues, including visceral mesoderm, somatice muscles and pharyngeal muscles. From stage 14 on, it is observed at muscle attachment sites.
(Vakaloglou et al., 2012)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
focal adhesion
inferred from direct assay
(Vakaloglou et al., 2012)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\parvin in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 11 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 19 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of parvin
Transgenic constructs containing regulatory region of parvin
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal, with Scer\GAL4Mef2.PR
lethal - all die before end of embryonic stage
lethal - all die before end of larval stage, with Scer\GAL4drm.7.1
lethal - all die before end of larval stage, with Scer\GAL4how-24B
lethal - all die before end of larval stage, with Scer\GAL4Mef2.PR
lethal - all die before end of larval stage, with Scer\GAL4Mef2.PU
lethal - all die during larval stage, with Scer\GAL4Mef2.PR
partially lethal - majority die, with Scer\GAL4elav.PLu
partially lethal - majority die, with Scer\GAL4en.PU
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
cell migration defective | larval stage, with Scer\GAL4ptc.PU
cell shape defective | larval stage, with Scer\GAL4en.PU
flight defective, with Scer\GAL4elav.PLu
increased cell death | larval stage, with Scer\GAL4en.PU
increased cell death | larval stage, with Scer\GAL4ptc.PU
small body | larval stage, with Scer\GAL4Mef2.PR
some die during embryonic stage
some die during larval stage, with Scer\GAL4Mef2.PR
some die during pupal stage, with Scer\GAL4ptc.PU
visible, with Scer\GAL4en-e16E
visible | adult stage, with Scer\GAL469B
visible | adult stage, with Scer\GAL4en.PU
visible | adult stage, with Scer\GAL4GMR.long
visible | adult stage, with Scer\GAL4ptc.PU
Phenotype manifest in
Allele
anterior-posterior compartment boundary of the wing disc, with Scer\GAL4ptc.PU
arista, with Scer\GAL4ptc.PU
embryonic/larval somatic muscle, with Scer\GAL4Mef2.PR
eye, with Scer\GAL469B
eye, with Scer\GAL4GMR.long
eye, with Scer\GAL4ptc.PU
filamentous actin, with Scer\GAL4en.PU
filamentous actin, with Scer\GAL4GMR.long
leg, with Scer\GAL4ptc.PU
maxillary palpus, with Scer\GAL448Y
ocellar bristle, with Scer\GAL4ptc.PU
ommatidium, with Scer\GAL4GMR.long
posterior crossvein, with Scer\GAL469B
scutellar bristle, with Scer\GAL4ptc.PU
wing, with Scer\GAL4elav.PLu
wing, with Scer\GAL4en.PU
wing, with Scer\GAL4en-e16E
wing disc posterior compartment, with Scer\GAL4en.PU
wing vein, with Scer\GAL4en.PU
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (7)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\PARVB
14 of 15
Yes
Yes
Hsap\PARVA
13 of 15
No
Yes
Hsap\PARVG
5 of 15
No
Yes
Hsap\SLC25A4
1 of 15
No
No
 
Hsap\SLC25A5
1 of 15
No
No
 
Hsap\SLC25A6
1 of 15
No
No
 
Hsap\SLC25A31
1 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (5)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Parvb
14 of 15
Yes
Yes
Mmus\Parva
13 of 15
No
Yes
Mmus\Parvg
5 of 15
No
Yes
Mmus\Slc25a4
1 of 15
No
No
Mmus\Slc25a31
1 of 15
No
No
Rattus norvegicus (Norway rat) (4)
Rnor\Parva
11 of 13
Yes
Yes
Rnor\Parvb
10 of 13
No
Yes
Rnor\Parvg
4 of 13
No
Yes
Rnor\Slc25a5
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (4)
Xtro\parvb
12 of 12
Yes
Yes
Xtro\parva
1 of 12
No
Yes
Xtro\slc25a4
1 of 12
No
No
Xtro\slc25a5
1 of 12
No
No
Danio rerio (Zebrafish) (7)
Drer\parvb
14 of 15
Yes
Yes
Drer\parvaa
13 of 15
No
Yes
Drer\parvab
13 of 15
No
Yes
Drer\parvg
5 of 15
No
Yes
Drer\slc25a4
1 of 15
No
No
Drer\slc25a5
1 of 15
No
No
Drer\slc25a6
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (8)
Cele\pat-6
11 of 15
Yes
Yes
Cele\ant-1.1
1 of 15
No
No
Cele\ant-1.2
1 of 15
No
No
Cele\ant-1.3
1 of 15
No
No
Cele\ant-1.4
1 of 15
No
No
Cele\C47E12.2
1 of 15
No
No
Cele\F25B4.7
1 of 15
No
No
Cele\R07E3.4
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190AI3 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Dmel\parvin
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00008364
Drosophila simulans
Dsim\GD17466
Drosophila sechellia
Dsec\GM22992
Drosophila erecta
Dere\GG19255
Drosophila yakuba
Dyak\GE15874
Drosophila ananassae
Dana\GF20217
Drosophila pseudoobscura pseudoobscura
Dpse\GA22568
Drosophila persimilis
Dper\GL15018
Drosophila willistoni
Dwil\GK25282
Drosophila virilis
Dvir\GJ15752
Drosophila mojavensis
Dmoj\GI16102
Drosophila grimshawi
Dgri\GH17695
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091507YC )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17013807
Musca domestica
House fly
Mdoa\17010590
Glossina morsitans
Tsetse fly
Gmor\GMOY004639
Glossina morsitans
Tsetse fly
Gmor\GMOY006034
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_10940
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00098
Mayetiola destructor
Hessian fly
Mdes\Mdes019316
Mayetiola destructor
Hessian fly
Mdes\Mdes008599
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL004855
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013461
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL010884
Anopheles darlingi
American malaria mosquito
Adar\ADAC006564
Anopheles darlingi
American malaria mosquito
Adar\ADAC007475
Anopheles darlingi
American malaria mosquito
Adar\ADAC006566
Anopheles gambiae
Malaria mosquito
Agam\AGAP002356
Anopheles gambiae
Malaria mosquito
Agam\ADT2_ANOGA
Anopheles gambiae
Malaria mosquito
Agam\AGAP006782
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ005941
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ012918
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ003742
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0A29 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA000683
Bombyx mori
Silkmoth
Bmor\BGIBMGA003829
Bombyx mori
Silkmoth
Bmor\Bmo.7664
Danaus plexippus
Monarch butterfly
Dple\DPOGS200915-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS205211-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS201402-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL012733
Heliconius melpomene
Postman butterfly
Hmel\HMEL012850
Heliconius melpomene
Postman butterfly
Hmel\HMEL006470
Heliconius melpomene
Postman butterfly
Hmel\HMEL006627
Apis florea
Little honeybee
Aflo\2446443316
Apis florea
Little honeybee
Aflo\2533445460
Apis florea
Little honeybee
Aflo\2619433828
Apis mellifera
Western honey bee
Amel\LOC409755
Apis mellifera
Western honey bee
Amel\Ant
Apis mellifera
Western honey bee
Amel\GB48178
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP22454
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP23135
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP13639
Bombus terrestris
Buff-tailed bumblebee
Bter\15209503
Bombus terrestris
Buff-tailed bumblebee
Bter\15214088
Bombus terrestris
Buff-tailed bumblebee
Bter\15214332
Linepithema humile
Argentine ant
Lhum\LH21300
Linepithema humile
Argentine ant
Lhum\LH12788
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:001258
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG014909
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007298
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG015052
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09963
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_05844
Tribolium castaneum
Red flour beetle
Tcas\TC002415
Tribolium castaneum
Red flour beetle
Tcas\TC000102
Tribolium castaneum
Red flour beetle
Tcas\TC010013
Tribolium castaneum
Red flour beetle
Tcas\TC000078
Pediculus humanus
Human body louse
Phum\PHUM551490
Pediculus humanus
Human body louse
Phum\PHUM581880
Pediculus humanus
Human body louse
Phum\PHUM022300
Pediculus humanus
Human body louse
Phum\PHUM580830
Rhodnius prolixus
Kissing bug
Rpro\RPRC009600
Rhodnius prolixus
Kissing bug
Rpro\RPRC004507
Cimex lectularius
Bed bug
Clec\CLEC000411
Cimex lectularius
Bed bug
Clec\CLEC000446
Cimex lectularius
Bed bug
Clec\CLEC001224
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008050
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002892
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI071353
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_14724
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09575
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X09XY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR009914
Strigamia maritima
European centipede
Smar\SMAR006044
Strigamia maritima
European centipede
Smar\SMAR009453
Ixodes scapularis
Black-legged tick
Isca\ISCW021754
Ixodes scapularis
Black-legged tick
Isca\ISCW021753
Ixodes scapularis
Black-legged tick
Isca\ISCW002088
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65305.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM72665.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65306.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79062.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur130g00030
Tetranychus urticae
Two-spotted spider mite
Turt\tetur20g00610
Tetranychus urticae
Two-spotted spider mite
Turt\tetur06g03290
Tetranychus urticae
Two-spotted spider mite
Turt\tetur130g00010
Tetranychus urticae
Two-spotted spider mite
Turt\tetur130g00020
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_39424
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_302682
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0ULB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_011739gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Slc25a4
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Slc25a5
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_011740gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Parvb
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000004997
Ciona intestinalis
Vase tunicate
Cint\LOC100178471
Ciona intestinalis
Vase tunicate
Cint\LOC100185620
Ciona intestinalis
Vase tunicate
Cint\LOC100177254
Gallus gallus
Domestic chicken
Ggal\PARVA
Gallus gallus
Domestic chicken
Ggal\PARVB
Gallus gallus
Domestic chicken
Ggal\SLC25A4
Gallus gallus
Domestic chicken
Ggal\SLC25A6
Gallus gallus
Domestic chicken
Ggal\SLC25A5
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v7.1)
Drosophila melanogaster (Fruit fly) (2)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Ant2
1 of 10
sesB
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Evidence
    References
    parvinUASp.mGFP6
    model of  cancer
    CEA
    (Chountala et al., 2012)
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    PARVB; parvin beta
    14 of 15
    608121
        PARVA; parvin alpha
        13 of 15
        608120
            PARVG; parvin gamma
            5 of 15
            608122
                Functional Complementation Data
                Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                Interactions
                Summary of Physical Interactions
                esyN Network Diagram
                Show neighbor-neighbor interactions:
                Select Layout:
                Legend:
                Protein
                RNA
                Selected Interactor(s)
                Interactions Browser
                View in Interactions Browser
                Please see the Physical Interaction reports below for full details
                protein-protein
                Physical Interaction
                Assay
                References
                parvin - Ilk
                two hybrid, experimental knowledge based
                (Hu et al., 2017.6.13, Guruharsha et al., 2011)
                parvin - stck
                anti tag coimmunoprecipitation, peptide massfingerprinting
                (Yoshigi et al., 2013, Kadrmas et al., 2004)
                Summary of Genetic Interactions
                esyN Network Diagram
                esyN Network Key:
                Suppression
                Enhancement
                View in Interactions Browser
                Please look at the allele data for full details of the genetic interactions
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                parvin
                enhanceable
                Chd64
                (Chountala et al., 2012)
                parvin
                suppressible
                Diap1
                (Chountala et al., 2012)
                parvin
                suppressible
                Diap1|Ilk
                (Chountala et al., 2012)
                parvin
                enhanceable
                Eip93F
                (Chountala et al., 2012)
                parvin
                suppressible
                Ilk
                (Chountala et al., 2012)
                parvin
                enhanceable
                mew
                (Chountala et al., 2012)
                parvin
                enhanceable
                mys
                (Chountala et al., 2012)
                parvin
                suppressible
                Pten
                (Chountala et al., 2012)
                parvin
                suppressible
                wech
                (Chountala et al., 2012)
                parvin
                suppressible
                Xrp1
                (Chountala et al., 2012)
                parvin
                enhanceable
                Zasp52
                (Chountala et al., 2012)
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                External Data
                Linkouts
                BioGRID - A database of protein and genetic interactions.
                DroID - A comprehensive database of gene and protein interactions.
                InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                MIST (protein-protein) - An integrated Molecular Interaction Database
                Pathways
                Gene Group - Pathway Membership (FlyBase)
                External Data
                Genomic Location and Detailed Mapping Data
                Chromosome (arm)
                X
                Recombination map
                1-64
                Cytogenetic map
                18E5-18F1
                Sequence location
                X:19,746,041..19,748,458 [+]
                FlyBase Computed Cytological Location
                Cytogenetic map
                Evidence for location
                18E5-18F1
                Limits computationally determined from genome sequence between P{EP}Sec61γEP1511 and P{EP}EP1116&P{EP}EP1344EP1344
                Experimentally Determined Cytological Location
                Cytogenetic map
                Notes
                References
                Experimentally Determined Recombination Data
                Location
                1-64
                (FlyBase, 2016)
                1-62.7
                (Comeron et al., 2012)
                Left of (cM)
                Right of (cM)
                Notes
                Stocks and Reagents
                Stocks (11)
                Genomic Clones (13)
                 

                Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                cDNA Clones (102)
                 

                Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                cDNA clones, fully sequences
                BDGP DGC clones
                Other clones
                  Drosophila Genomics Resource Center cDNA clones

                  For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                  cDNA Clones, End Sequenced (ESTs)
                  BDGP DGC clones
                  Other clones
                  RNAi and Array Information
                  Linkouts
                  DRSC - Results frm RNAi screens
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  Antibody Information
                  Laboratory Generated Antibodies
                   
                  polyclonal
                  (Vakaloglou et al., 2012)
                  Commercially Available Antibodies
                   
                  Other Information
                  Relationship to Other Genes
                  Source for database identify of
                  Source for identity of: parvin CG32528
                  (Vakaloglou et al., 2012)
                  Source for database merge of
                  Additional comments
                  Annotation CG12533 split into CG32530 and CG32528 in release 3 of the genome annotation.
                  (FlyBase Genome Annotators, 2002-2003)
                  Other Comments
                  dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
                  (Kiger et al., 2003)
                  Origin and Etymology
                  Discoverer
                  Etymology
                  Identification
                  External Crossreferences and Linkouts ( 33 )
                  Sequence Crossreferences
                  NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                  GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                  GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                  RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                  UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                  Other crossreferences
                  Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                  Flygut - An atlas of the Drosophila adult midgut
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                  InterPro - A database of protein families, domains and functional sites
                  KEGG Genes - Molecular building blocks of life in the genomic space.
                  modMine - A data warehouse for the modENCODE project
                  Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                  Linkouts
                  BioGRID - A database of protein and genetic interactions.
                  DroID - A comprehensive database of gene and protein interactions.
                  DRSC - Results frm RNAi screens
                  FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                  FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                  FlyMine - An integrated database for Drosophila genomics
                  Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                  InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                  MIST (protein-protein) - An integrated Molecular Interaction Database
                  Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                  Synonyms and Secondary IDs (4)
                  Datasets (0)
                  Study focus (0)
                  Experimental Role
                  Project
                  Project Type
                  Title
                  References (40)