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General Information
Symbol
Dmel\Muc12Ea
Species
D. melanogaster
Name
Mucin 12Ea
Annotation Symbol
CG32602
Feature Type
FlyBase ID
FBgn0052602
Gene Model Status
Stock Availability
Gene Snapshot
Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
Key Links
Genomic Location
Cytogenetic map
Sequence location
X:14,277,735..14,288,161 [+]
Recombination map

1-48

RefSeq locus
NC_004354 REGION:14277735..14288161
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
GO Summary Ribbons
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Molecular Function (GO)
    [Detailed GO annotations]
    Experimental Evidence
    -
    Predictions / Assertions
    Summaries
    Gene Group (FlyBase)
    MUCINS -
    Mucin/mucin-like proteins are heavily O-glycosylated proteins characterized by proline, threonine and serine tandem repeats. Mucins form extracellular matrix networks or act as mucosal secretion lubricants. (Adapted from FBrf0205867.)
    Gene Model and Products
    Number of Transcripts
    1
    Number of Unique Polypeptides
    1

    Please see the GBrowse view of Dmel\Muc12Ea or the JBrowse view of Dmel\Muc12Ea for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Comments on Gene Model

    39-bp (13-aa) repeat motif

    Supported by strand-specific RNA-Seq data.

    Gene model reviewed during 5.53

    Gene model reviewed during 6.28

    Sequence Ontology: Class of Gene
    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    Assoc. CDS (aa)
    FBtr0475073
    10181
    3321
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Polypeptide Data
    Annotated Polypeptides
    Name
    FlyBase ID
    Predicted MW (kDa)
    Length (aa)
    Theoretical pI
    RefSeq ID
    GenBank
    FBpp0423273
    338.5
    3321
    10.78
    Polypeptides with Identical Sequences

    There is only one protein coding transcript and one polypeptide associated with this gene

    Additional Polypeptide Data and Comments
    Reported size (kDa)
    Comments
    External Data
    Crossreferences
    Linkouts
    Sequences Consistent with the Gene Model
    Nucleotide / Polypeptide Records
       
      Mapped Features

      Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Muc12Ea using the Feature Mapper tool.

      External Data
      Crossreferences
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      Linkouts
      Gene Ontology (4 terms)
      Molecular Function (1 term)
      Terms Based on Experimental Evidence (0 terms)
      Terms Based on Predictions or Assertions (1 term)
      CV Term
      Evidence
      References
      Biological Process (1 term)
      Terms Based on Experimental Evidence (1 term)
      CV Term
      Evidence
      References
      Terms Based on Predictions or Assertions (0 terms)
      Cellular Component (2 terms)
      Terms Based on Experimental Evidence (0 terms)
      Terms Based on Predictions or Assertions (2 terms)
      CV Term
      Evidence
      References
      inferred by curator from GO:0007304
      inferred from sequence model
      Expression Data
      Expression Summary Ribbons
      Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
      For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
      Transcript Expression
      in situ
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      RT-PCR
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      Additional Descriptive Data
      Marker for
       
      Subcellular Localization
      CV Term
      Polypeptide Expression
      Additional Descriptive Data
      Marker for
       
      Subcellular Localization
      CV Term
      Evidence
      References
      Expression Deduced from Reporters
      High-Throughput Expression Data
      Associated Tools

      GBrowse - Visual display of RNA-Seq signals

      View Dmel\Muc12Ea in GBrowse 2
      RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
      Reference
      See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
      Developmental Proteome: Life Cycle
      Developmental Proteome: Embryogenesis
      External Data and Images
      Linkouts
      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
      Flygut - An atlas of the Drosophila adult midgut
      Images
      Alleles, Insertions, and Transgenic Constructs
      Classical and Insertion Alleles ( 0 )
      For All Classical and Insertion Alleles Show
       
      Other relevant insertions
      Transgenic Constructs ( 3 )
      For All Alleles Carried on Transgenic Constructs Show
      Transgenic constructs containing/affecting coding region of Muc12Ea
      Transgenic constructs containing regulatory region of Muc12Ea
      Deletions and Duplications ( 0 )
      Phenotypes
      Orthologs
      Human Orthologs (via DIOPT v7.1)
      Homo sapiens (Human) (18)
      Species\Gene Symbol
      Score
      Best Score
      Best Reverse Score
      Alignment
      Complementation?
      Transgene?
      3 of 15
      Yes
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      No
      1 of 15
      No
      No
      1 of 15
      No
      No
      1 of 15
      No
      No
      1 of 15
      No
      No
      1 of 15
      No
      No
      1 of 15
      No
      Yes
      1 of 15
      No
      No
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      No
      1 of 15
      No
      No
      Model Organism Orthologs (via DIOPT v7.1)
      Mus musculus (laboratory mouse) (10)
      Species\Gene Symbol
      Score
      Best Score
      Best Reverse Score
      Alignment
      Complementation?
      Transgene?
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      Rattus norvegicus (Norway rat) (8)
      1 of 13
      Yes
      Yes
      1 of 13
      Yes
      Yes
      1 of 13
      Yes
      No
      1 of 13
      Yes
      No
      1 of 13
      Yes
      Yes
      1 of 13
      Yes
      No
      1 of 13
      Yes
      Yes
      1 of 13
      Yes
      No
      Xenopus tropicalis (Western clawed frog) (1)
      1 of 12
      Yes
      Yes
      Danio rerio (Zebrafish) (7)
      1 of 15
      Yes
      No
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      Caenorhabditis elegans (Nematode, roundworm) (8)
      2 of 15
      Yes
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      No
      1 of 15
      No
      Yes
      1 of 15
      No
      Yes
      1 of 15
      No
      No
      Arabidopsis thaliana (thale-cress) (2)
      1 of 9
      Yes
      Yes
      1 of 9
      Yes
      No
      Saccharomyces cerevisiae (Brewer's yeast) (11)
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      No
      1 of 15
      Yes
      No
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      Yes
      1 of 15
      Yes
      Yes
      Schizosaccharomyces pombe (Fission yeast) (5)
      1 of 12
      Yes
      Yes
      1 of 12
      Yes
      Yes
      1 of 12
      Yes
      Yes
      1 of 12
      Yes
      No
      1 of 12
      Yes
      No
      Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190GX6 )
      Organism
      Common Name
      Gene
      AAA Syntenic Ortholog
      Multiple Dmel Genes in this Orthologous Group
      Drosophila melanogaster
      fruit fly
      Drosophila simulans
      Drosophila erecta
      Drosophila ananassae
      Drosophila pseudoobscura pseudoobscura
      Drosophila virilis
      Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915054B )
      Organism
      Common Name
      Gene
      Multiple Dmel Genes in this Orthologous Group
      Mayetiola destructor
      Hessian fly
      Mayetiola destructor
      Hessian fly
      Culex quinquefasciatus
      Southern house mosquito
      Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0GQH )
      Organism
      Common Name
      Gene
      Multiple Dmel Genes in this Orthologous Group
      Bombyx mori
      Silkmoth
      Bombyx mori
      Silkmoth
      Bombyx mori
      Silkmoth
      Danaus plexippus
      Monarch butterfly
      Danaus plexippus
      Monarch butterfly
      Danaus plexippus
      Monarch butterfly
      Heliconius melpomene
      Postman butterfly
      Heliconius melpomene
      Postman butterfly
      Heliconius melpomene
      Postman butterfly
      Apis florea
      Little honeybee
      Apis mellifera
      Western honey bee
      Bombus impatiens
      Common eastern bumble bee
      Bombus impatiens
      Common eastern bumble bee
      Bombus impatiens
      Common eastern bumble bee
      Bombus impatiens
      Common eastern bumble bee
      Bombus impatiens
      Common eastern bumble bee
      Bombus terrestris
      Buff-tailed bumblebee
      Bombus terrestris
      Buff-tailed bumblebee
      Linepithema humile
      Argentine ant
      Linepithema humile
      Argentine ant
      Linepithema humile
      Argentine ant
      Linepithema humile
      Argentine ant
      Megachile rotundata
      Alfalfa leafcutting bee
      Megachile rotundata
      Alfalfa leafcutting bee
      Megachile rotundata
      Alfalfa leafcutting bee
      Megachile rotundata
      Alfalfa leafcutting bee
      Megachile rotundata
      Alfalfa leafcutting bee
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Nasonia vitripennis
      Parasitic wasp
      Dendroctonus ponderosae
      Mountain pine beetle
      Tribolium castaneum
      Red flour beetle
      Tribolium castaneum
      Red flour beetle
      Tribolium castaneum
      Red flour beetle
      Tribolium castaneum
      Red flour beetle
      Tribolium castaneum
      Red flour beetle
      Pediculus humanus
      Human body louse
      Pediculus humanus
      Human body louse
      Pediculus humanus
      Human body louse
      Pediculus humanus
      Human body louse
      Rhodnius prolixus
      Kissing bug
      Rhodnius prolixus
      Kissing bug
      Rhodnius prolixus
      Kissing bug
      Cimex lectularius
      Bed bug
      Cimex lectularius
      Bed bug
      Cimex lectularius
      Bed bug
      Cimex lectularius
      Bed bug
      Acyrthosiphon pisum
      Pea aphid
      Acyrthosiphon pisum
      Pea aphid
      Acyrthosiphon pisum
      Pea aphid
      Acyrthosiphon pisum
      Pea aphid
      Acyrthosiphon pisum
      Pea aphid
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Zootermopsis nevadensis
      Nevada dampwood termite
      Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X00AS )
      Organism
      Common Name
      Gene
      Multiple Dmel Genes in this Orthologous Group
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Strigamia maritima
      European centipede
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Ixodes scapularis
      Black-legged tick
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Stegodyphus mimosarum
      African social velvet spider
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Tetranychus urticae
      Two-spotted spider mite
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Daphnia pulex
      Water flea
      Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02UO )
      Organism
      Common Name
      Gene
      Multiple Dmel Genes in this Orthologous Group
      Strongylocentrotus purpuratus
      Purple sea urchin
      Strongylocentrotus purpuratus
      Purple sea urchin
      Strongylocentrotus purpuratus
      Purple sea urchin
      Strongylocentrotus purpuratus
      Purple sea urchin
      Strongylocentrotus purpuratus
      Purple sea urchin
      Ciona intestinalis
      Vase tunicate
      Ciona intestinalis
      Vase tunicate
      Ciona intestinalis
      Vase tunicate
      Ciona intestinalis
      Vase tunicate
      Gallus gallus
      Domestic chicken
      Gallus gallus
      Domestic chicken
      Gallus gallus
      Domestic chicken
      Gallus gallus
      Domestic chicken
      Paralogs
      Paralogs (via DIOPT v7.1)
      Drosophila melanogaster (Fruit fly) (11)
      2 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      1 of 10
      Human Disease Associations
      FlyBase Human Disease Model Reports
        Disease Model Summary Ribbon
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Allele
        Disease
        Evidence
        References
        Potential Models Based on Orthology ( 0 )
        Human Ortholog
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Allele
        Disease
        Interaction
        References
        Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)
        Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
        Homo sapiens (Human)
        Gene name
        Score
        OMIM
        OMIM Phenotype
        DO term
        Complementation?
        Transgene?
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Interactions Browser

        Please see the Physical Interaction reports below for full details
        RNA-protein
        Physical Interaction
        Assay
        References
        Summary of Genetic Interactions
        esyN Network Diagram
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        X
        Recombination map

        1-48

        Cytogenetic map
        Sequence location
        X:14,277,735..14,288,161 [+]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        12E7-12E7
        Limits computationally determined from genome sequence between P{EP}l(1)G0007EP764 and P{EP}EP1599
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        Experimentally Determined Recombination Data
        Location
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (3)
        Genomic Clones (18)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (0)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequences
        BDGP DGC clones
          Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
                Other clones
                  RNAi and Array Information
                  Linkouts
                  DRSC - Results frm RNAi screens
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  Antibody Information
                  Laboratory Generated Antibodies
                   
                  Commercially Available Antibodies
                   
                  Other Information
                  Relationship to Other Genes
                  Source for database identify of

                  Source for identity of: Muc12Ea CG32602

                  Source for database merge of
                  Additional comments
                  Other Comments
                  Origin and Etymology
                  Discoverer
                  Etymology
                  Identification
                  External Crossreferences and Linkouts ( 21 )
                  Sequence Crossreferences
                  NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                  GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                  UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                  Other crossreferences
                  Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                  Flygut - An atlas of the Drosophila adult midgut
                  GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                  iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                  KEGG Genes - Molecular building blocks of life in the genomic space.
                  modMine - A data warehouse for the modENCODE project
                  Linkouts
                  DroID - A comprehensive database of gene and protein interactions.
                  DRSC - Results frm RNAi screens
                  FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                  FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                  FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                  FlyMine - An integrated database for Drosophila genomics
                  InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                  Synonyms and Secondary IDs (4)
                  Datasets (0)
                  Study focus (0)
                  Experimental Role
                  Project
                  Project Type
                  Title
                  References (28)