General Information Symbol Dmel\ Tango5Species D. melanogaster Name Transport and Golgi organization 5 Annotation symbol CG32675 Feature type protein_coding_gene FlyBase ID FBgn0052675 Gene Model Status Current Stock availability 5 publicly
available Genomic Location Chromosome (arm) X Recombination map Cytogenetic map 9E4-9E6 Sequence location X:10,654,081..10,658,270 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Transport and Golgi organization 5 is referred to in FlyBase by the symbol
Dmel\Tango5 (CG32675, FBgn0052675). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. There is experimental evidence that it is involved in the
biological process : Golgi organization; protein secretion.
7 alleles are reported . No phenotypic data is available. It has
5 annotated transcripts and
5 annotated polypeptides . Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, larval/adult salivary gland, adult ovary, adult male reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1634561_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of Tango5. Gene sequence location is
X:10654081..10658270 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
9E3-9E4
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.47
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) inferred from direct assay
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
100.5
Larval Midgut
128
Larval Hindgut
87.7
Larval Malpighian Tubules
150.1
Larval Fat Body
132.7
Larval Salivary Gland
125.3
Larval Trachea
37.45
Larval Carcass
55.675
Adult Head
124.2
Adult Eye
104.225
Adult Brain
188.3
Adult Thoracic-Abdominal Ganglion
220.2
Adult Crop
110.1
Adult Midgut
188.4
Adult Hindgut
141.5
Adult Malpighian Tubules
119.2
Adult Fat Body
159.9
Adult Salivary Gland
209
Adult Heart
80.925
Adult VirginFemale Spermatheca
74.4
Adult InseminatedFemale Spermatheca
50.4
Adult Ovary
128
Adult Testis
163
Adult Male Accessory Gland
214.5
Adult Carcass
144.8
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
124.2
NA
Eye
104.225
NA
Brain
188.3
100.5
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
220.2
NA
Crop
110.1
128
Midgut
188.4
87.7
Hindgut
141.5
150.1
Malpighian Tubules
119.2
132.7
Fat Body
159.9
125.3
Salivary Gland
209
NA
Heart
80.925
37.45
Trachea
NA
NA
VirginFemale Spermatheca
74.4
NA
InseminatedFemale Spermatheca
50.4
NA
Ovary
128
NA
Testis
163
NA
Male Accessory Gland
214.5
55.675
Carcass
144.8
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
(28)
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
16
central nervous system, pupae P8
17
head, virgin 1-day female
16
head, virgin 4-day female
15
head, virgin 20-day female
14
head, mated 1-day female
14
head, mated 4-day female
17
head, mated 20-day female
11
head, mated 1-day male
19
head, mated 4-day male
24
head, mated 20-day male
22
salivary gland, larvae L3 wandering
4
salivary gland, white prepupae
14
digestive system, larvae L3 wandering
28
digestive system, 1-day adult
14
digestive system, 4-day adult
18
digestive system, 20-day adult
14
fat body, larvae L3 wandering
8
fat body, white prepupae
12
fat body, pupae P8
6
carcass, larvae L3 wandering
7
carcass, 1-day adult
10
carcass, 4-day adult
11
carcass, 20-day adult
11
ovary, virgin 4-day female
18
ovary, mated 4-day female
18
testis, mated 4-day male
20
accessory gland, mated 4-day male
12
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
(31)
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
(29)
adult female 30day
(31)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
25
embryo 02-04hr
17
embryo 04-06hr
17
embryo 06-08hr
16
embryo 08-10hr
14
embryo 10-12hr
19
embryo 12-14hr
18
embryo 14-16hr
17
embryo 16-18hr
15
embryo 18-20hr
17
embryo 20-22hr
19
embryo 22-24hr
17
larva L1
17
larva L2
17
larva L3 12hr old
12
larva L3 puffstage 1-2
10
larva L3 puffstage 3-6
15
larva L3 puffstage 7-9
23
white prepupae new
31
white prepupae 12hr
17
white prepupae 24hr
15
pupae 2d postWPP
15
pupae 3d postWPP
13
pupae 4d postWPP
16
adult male 01day
20
adult male 05day
24
adult male 30day
21
adult female 01day
20
adult female 05day
29
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
117
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(32)
Schneider line 2 Sg4
23
embryonic 1182-4H
(33)
embryonic GM2
(70)
embryonic Kc167
(117)
embryonic S1
15
embryonic S3
(35)
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
(38)
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
(117)
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
117
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
117
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
(33)
embryonic GM2
(70)
embryonic Kc167
(117)
embryonic S1
15
embryonic S3
(35)
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
(38)
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
117
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
32
Schneider line 2 Sg4
23
embryonic 1182-4H
33
embryonic GM2
70
embryonic Kc167
117
embryonic S1
15
embryonic S3
35
leg disc CME L1
24
wing disc CME-W2
17
wing disc ML-DmD8
16
wing disc ML-DmD9
23
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
19
haltere disc ML-DmD17-c3
23
eye-antennal disc ML-DmD11
14
antennal disc ML-DmD20-c5
8
mixed discs ML-DmD4-c1
21
CNS ML-DmBG1-c1
21
CNS ML-DmBG2-c2
22
tumorous blood cells mbn2
38
ovary fGS/OSS
19
ovary OSC
19
ovary OSS
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
(28)
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
14
cold shock, 4-day adult
13
heat shock, 4-day adult
12
Cadmium 50 mM 6 hrs, larvae L3
6
Cadmium 50 mM 12 hrs, larvae L3
9
Cadmium 50 mM 48 hrs, 4-day adult
11
Cadmium 100 mM 48 hrs, 4-day adult
20
Copper 0.5 mM 12 hrs, larvae L3
6
Copper 15 mM 48 hrs, 4-day adult
28
Zinc 5 mM 12 hrs, larvae L3
7
Zinc 4.5 mM 48 hrs, 4-day adult
18
Ethanol 2.5% 3 hrs, larvae L3
19
Ethanol 5% 3 hrs, larvae L3
8
Ethanol 10% 3 hrs, larvae L3
7
Caffeine 1.5 mg/ml 4 hrs, larvae L3
8
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
11
Paraquat 5 mM 48 hrs, 4-day adult
17
Paraquat 10 mM 48 hrs, 4-day adult
21
Rotenone 2 μg 12 hrs, larvae L3
7
Rotenone 8 μg 12 hrs, larvae L3
7
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 4 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of enhancer trap
insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 3 unique terms )There is no information supporting a
molecular function term for this gene.
(Based on a review of available data before: 2006)
Terms Based on
Experimental Evidence ( 3 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component inferred from direct assay
Terms Based on Predictions or
Assertions ( 0 terms ) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (38)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6B8K01 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG68PMTV )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG6WSV6M )
Apis mellifera
Western honey bee
Amel\GB49955
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG000859
Y
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH17514
Y
Atta cephalotes
Leafcutter ant
Acep\ACEP12941
Y
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO19637
Y
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL14575
Y
Linepithema humile
Argentine ant
Lhum\LH11477
Y
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB18336
Y
Acyrthosiphon pisum
Pea aphid
Y
Pediculus humanus
Human body louse
Y
Tribolium castaneum
Red flour beetle
Y
Orthologs in non-Insect Arthropods
(EOG6BNZTV )
Daphnia pulex
Water flea
Y
Ixodes scapularis
Deer tick
Y
Orthologs in non-Arthropod Metazoa
(EOG64R5TJ )
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 5 )Bloomington VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 104 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: Tango5 CG32675
Source for database merge of Additional comments Annotation CG1534 split into CG32672 and CG32675 in release 3 of the genome annotation.
Other Comments dsRNA directed against this gene has been used in a screen for genes required for constitutive protein secretion.
dsRNA directed against
Tango5 inhibits protein secretion in S2 cells and results in fusion of Golgi membranes with the endoplasmic reticulum in more than 50% of the treated cells.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences Linkouts
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 5 )Reported As Symbol Synonym Name Synonym Transport and Golgi organization 5
Secondary FlyBase
IDs References ( 17 )Research paper Díaz-Castillo and Ranz, 2012, Mol. Biol. Evol. 29(9): 2105--2108Nuclear chromosome dynamics in the Drosophila male germ line contribute to the nonrandom genomic distribution of retrogenes. [FBrf0219274] Ambegaokar and Jackson, 2011, Hum. Mol. Genet. 20(24): 4947--4977Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. [FBrf0217690] Kim et al., 2010, BMC Cell Biol. 11: 9A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes. [FBrf0209948] Bard et al., 2006, Nature 439(7076): 604--607Functional genomics reveals genes involved in protein secretion and Golgi organization. [FBrf0191232] Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Peter et al., 2002, EMBO Rpts 3(1): Supplementary material. PX-lines.txt. [FBrf0173176] Swanson et al., 2001, Proc. Natl. Acad. Sci. USA 98: Gene characteristics and dN/dS ratios of Drosophila simulans. [FBrf0137427] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping projectDPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members, 2001-, (Computer file)(Computer file) [FBrf0132177] FlyBase analysis FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation.FlyBase curation. [FBrf0105495]