• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Dh31-R1

General Information
Symbol	Dmel\Dh31-R1	Species	D. melanogaster
Name	Diuretic hormone 31 receptor 1	Annotation symbol	CG32843
Feature type	protein_coding_gene	FlyBase ID	FBgn0052843
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	CG17415
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	49F15-50A1	Sequence location	2R:9,155,302..9,183,429 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Diuretic hormone 31 receptor 1 is referred to in FlyBase by the symbol Dmel\Dh31-R1 (CG32843, FBgn0052843). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: diuretic hormone receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: G-protein coupled receptor signaling pathway. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GPCR, family 2, calcitonin receptor-like; GPCR, family 2, extracellular hormone receptor domain; GPCR, family 2, secretin-like; GPCR, family 2, secretin-like, conserved site; GPCR, family 2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut. Gene sequence location is 2R:9155302..9183429.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	References Jumbo-Lucioni et al., 2010, BMC Genomics 11: 297 Sequence features HFA06647 HFA06669 BKN28756
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 49F15-50A1   Limits computationally determined from genome sequence between P{EP}DpEP358 and P{lacW}drkk13809&P{EP}mip120EP606
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Dh31-R1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	3' UTR contains an ORF that is conserved among close Drosophila species (potential peptide160 aa in length; possible stop-codon suppression).
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Dh31-R1-RA FBtr0087755  NM_165979   3267   443
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Dh31-R1-PA   FBpp0086868   48.9   443   7.70     NP_725278   AAN16138
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GPCR, family 2, secretin-like (IPR000832) GPCR, family 2, extracellular hormone receptor domain (IPR001879) GPCR, family 2, calcitonin receptor-like (IPR003287) GPCR, family 2-like (IPR017981) GPCR, family 2, secretin-like, conserved site (IPR017983)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAN16138   AX254569   AX254570   AY071196 AAL48818   BI171710   BI231810   BI605585   BI606266   CO186154   CO265820   CO280892   CO280901   CO291374   CO292758   CO297878   CO339375   CZ477932   CZ489297   DD177544   EC061934   EC073398   EC085377   EC198934   EC202072   EC224154   EC256505   EC260029   GH751950   GH754242   GH756136   GH757155   GH759203   GH761023   GH780747   GH780803   GH781228   GH786865   GH788255   GH790819   GH790841   GH791947   GH792845   GH794586   GH797302   GH798655   GH800320   GH808493   GH809020   GH809240   GH809971   GH810595   GH810750   GH813339   GH814992   GH815906   GH815946   GH817991   GH818100   GH818779   GH820135   GH822863   GH823535   GH827685   GH829328   GH829760   GH831208   GH831704   GH834888   GH836842   GH838673   GH842157   GH843482   GH844058   GH844552   GH848029   GH851289   GH856352   GH857042   GH857474   GH862775   GH867302   GH869529   GH870451   GH870602   GH873633   GH874660   GH874768   GH876090   GH881065   GH882974   GH883887   GH884763   GH889329   GH890898   GH898735   GH901651   GH901948   GH902972   GH903569   GH906329   GH907251   GH908011   GH909609   GH910547   GH910827   GH915608   GH916440   GH917108   GH920580   GH926668   GH928693   GH931639   GH933528   GH933537   GH936286   GH938395
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SZ11 A1Z9B7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0052843    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0052843 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0052843 expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr  (202) embryo 16-18hr  (329) embryo 18-20hr  (501) embryo 20-22hr  (924) embryo 22-24hr  (982) larva L1  (793) larva L2  (382) larva L3 12hr old  (171) larva L3 puffstage 1-2  (161) larva L3 puffstage 3-6  (127) larva L3 puffstage 7-9  (135) white prepupae new  (147) white prepupae 12hr  (152) white prepupae 24hr  (253) pupae 2d postWPP  (292) pupae 3d postWPP  (352) pupae 4d postWPP  (237) adult male 01day  (491) adult male 05day  (487) adult male 30day  (570) adult female 01day  (306) adult female 05day  (138) adult female 30day  (179) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0052843 expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr  (202) embryo 16-18hr  (329) embryo 18-20hr  (501) embryo 20-22hr  (924) embryo 22-24hr  (982) larva L1  (793) larva L2  (382) larva L3 12hr old  (171) larva L3 puffstage 1-2  (161) larva L3 puffstage 3-6  127 larva L3 puffstage 7-9  135 white prepupae new  (147) white prepupae 12hr  (152) white prepupae 24hr  (253) pupae 2d postWPP  (292) pupae 3d postWPP  (352) pupae 4d postWPP  (237) adult male 01day  (491) adult male 05day  (487) adult male 30day  (570) adult female 01day  (306) adult female 05day  138 adult female 30day  (179) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    1 embryo 04-06hr    5 embryo 06-08hr    5 embryo 08-10hr    10 embryo 10-12hr    39 embryo 12-14hr    73 embryo 14-16hr    202 embryo 16-18hr    329 embryo 18-20hr    501 embryo 20-22hr    924 embryo 22-24hr    982 larva L1    793 larva L2    382 larva L3 12hr old    171 larva L3 puffstage 1-2    161 larva L3 puffstage 3-6    127 larva L3 puffstage 7-9    135 white prepupae new    147 white prepupae 12hr    152 white prepupae 24hr    253 pupae 2d postWPP    292 pupae 3d postWPP    352 pupae 4d postWPP    237 adult male 01day    491 adult male 05day    487 adult male 30day    570 adult female 01day    306 adult female 05day    138 adult female 30day    179 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0052843    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0052843 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart no informative data Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0052843 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CT30298;CG32843-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Dh31-R1f05546 viable, with Scer\GAL4pnr-MD237 Dh31-R1GD3782 Sterility Allele fertile Dh31-R1f05546 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of Dh31-R1 Class Mutagen Stocks Known lesion Dh31-R1e00021 piggyBac transposase 1 -- Dh31-R1f05546 piggyBac transposase 1 -- Dh31-R1f06589 piggyBac transposase 1 -- Dh31-R1MB00175 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Dh31-R1 Class Mutagen Stocks Known lesion Dh31-R1GD3782 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Dh31-R1JF01945 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Dh31-R1KK108756 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK108756} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}Dh31-R1e00021 NA PBac{WH}Dh31-R1f05546 NA PBac{WH}Dh31-R1f06589 NA insertion of enhancer trap binary system Mi{ET1}Dh31-R1MB00175 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function
CV term Evidence References
diuretic hormone receptor activity inferred from direct assay (Johnson et al., 2005)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
calcitonin receptor activity inferred from sequence or structural similarity (Brody and Cravchik, 2000, Radford et al., 2002) inferred from sequence or structural similarity with UniProtKB:Q63118 (FlyBase, 1992-) neuropeptide receptor activity inferred from sequence or structural similarity (Hewes and Taghert, 2001)
Biological Process
CV term Evidence References
G-protein coupled receptor signaling pathway inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR003287, InterPro:IPR017983 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Brody and Cravchik, 2000, Hewes and Taghert, 2001)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000832 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Brody and Cravchik, 2000, Hewes and Taghert, 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Dh31-R1 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0052843 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36475
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11195 Dere\GG22503 Dgri\GH20277 Dmoj\GI19445 Dper\GL11103 Dpse\GA17177 Dsec\GM20289 Dsim\GD25770 Dvir\GJ21197 Dwil\GK17827 Dyak\GE13373
Curated drosophilid orthologs	Dpse\GA17177
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010043-PA Aedes aegypti (mosquito) XP_396046.3 Apis mellifera (honey bee) XP_001943752.1 Acyrthosiphon pisum (pea aphid) 241491 Branchiostoma floridae (lancelet) BGIBMGA009927-PA Bombyx mori (silk worm) ENSBTAP00000011169 Bos taurus (bovine) ENSCAFP00000021740 Canis familiaris (dog) CPIJ014419 Culex pipens (mosquito) ENSCPOP00000000911 Cavia porcellus (guinea pig) 221530 Capitella spl (polychaete worm) 299723 Daphnia pulex (daphnia) ENSDARP00000021509 Danio rerio (zebra fish) ENSDARP00000051942 Danio rerio (zebra fish) ENSECAP00000011151 Equus caballus (horse) ENSGACP00000003115 Gymnopilus aculeatus (mushroom) ENSGALP00000004139 Gallus gallus (chicken) ENSP00000376177 Homo sapiens (human) 172709 Lottia gigantea (owl limpet) ENSMODP00000013390 Monodelphis domestica (gray opossum) ENSMMUP00000012352 Macaca mulatta (rhesus monkey) ENSMUSP00000097527 Mus musculus (house mouse) XP_001601649.1 Nasonia vitripennis (wasp) ENSORLP00000018105 Oryzias latipes (japanese killifish) PHUM005412-PA Pediculus humanus (human body louse) ENSPPYP00000014533 Pongo pygmaeus (orangutan) ENSPTRP00000021750 Pan troglodytes (chimpanzee) ENSRNOP00000006462 Rattus norvegicus (norway rat) XP_969030.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011722 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000016740 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000030402 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14389 NV14697 LH13022 ISCW012970 FBgn0231052 FBgn0219826 FBgn0208330 FBgn0197051 FBgn0175172 JGI_V11_299723 FBgn0077191 FBgn0148713 FBgn0142183 FBgn0127741 FBgn0114674 FBgn0088235 CPIJ014419 BGIBMGA009927 ACYPI007222 ACYPI001361 GB12975 GPRCAL1 PHUM428070 GLEAN_02694
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	22718 y1 w67c23; Mi{ET1}Dh31-R1MB00175 25925 y1 v1; P{TRiP.JF01945}attP2/TM3, Sb1
Harvard	- PBac{RB}Dh31-R1e00021 - PBac{WH}Dh31-R1f05546 - PBac{WH}Dh31-R1f06589
VDRC	v101995 P{KK108756}VIE-260B v8777 w1118; P{GD3782}v8777
Genomic Clones ( 1 )
	BACR05M17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 109 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE24343
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE13540 RH71382 RH72515
Other clones	33660 41893 42127 53648 72368 98924 214381.33 214413.34 EK016402 EK078109 EK143812 EK155358 EK155416 EK170821 EK200913 EP01810 RP003057646 RP003062829 RP003069109 RP003069820 RP003073008 RP003074081 RP003076442 RP003089022 RP003095653 RP003099866 RP003100364 RP003102058 RP003113466 RP003125350 RP003125661 RP003135570 RP003136060 RP003155713 RP003155928 RP003161367 RP003172514 RP003173687 RP003179473 RP003181654 RP003187080 RP003192241 RP003196693 RP003204846 RP003225159 RP003231334 RP003234600 RP003238126 RP003244411 RP003249127 RP003251049 RP003256327 RP003256756 RP003268235 RP003268555 RP003271369 RP003275887 RP003281939 RP003298329 RP003303480 RP003313594 RP003315940 RP003319651 RP003320107 RP003332449 RP003338425 RP003350225 RP003351252 RP003356134 RP003381161 RP003397151 RP003397780 RP003415836 RP003419368 RP003425130 RP003429026 RP003438645 RP003442565 RP003453894 RP003471551 RP003474753 RP003474966 RP003477033 RP003492138 RP003495200 RP003496230 RP003501697 RP003503945 RP003506707 RP003522503 RP003550717 RP003551502 RP003552751 RP003564499 RP003568137 RP003569561 RP003584651 RP003586351 RP003588866 RP003592475 RP003603279 RP003620536 RP003626669 RP003630707 RP003642872
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0052843 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36475
Antibody Information
	polyclonal (Johnson et al., 2005)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Dh31-R1 CG32843 (Johnson et al., 2005)
Source for database merge of	Source for merge of: CG17415 CG17043 (FlyBase Genome Annotators, 2002-2003) Source for merge of: CG32843 anon-WO0170980.136 anon-WO0170980.137 (FlyBase, 1996-)
Additional comments	Annotations CG17415 and CG17043 merged as CG32843 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of CG32843 anon-WO0170980.136 anon-WO0170980.137 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_165979 RefSeq (Proteins) • NP_725278 DDBJ / EMBL / GenBank • AAL48818 AAN16138 AAN16138.1 AX254569 AX254570 AY071196 BI231810 CZ477932 CZ489297 DD177544 Entrez Gene - A searchable database of RefSeq genes. • 36475 UniProtKB/TrEMBL • A1Z9B7 Q8SZ11
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GPCR, family 2, secretin-like (IPR000832) GPCR, family 2, extracellular hormone receptor domain (IPR001879) GPCR, family 2, calcitonin receptor-like (IPR003287) GPCR, family 2-like (IPR017981) GPCR, family 2, secretin-like, conserved site (IPR017983)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0052843 DRSC - Results from RNAi screens. • FBgn0052843 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0052843 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CT30298;CG32843-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0052843 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36475 InParanoid A subset of ortholog calls from InParanoid. • AAEL010043-PA Aedes aegypti (mosquito) XP_396046.3 Apis mellifera (honey bee) XP_001943752.1 Acyrthosiphon pisum (pea aphid) 241491 Branchiostoma floridae (lancelet) BGIBMGA009927-PA Bombyx mori (silk worm) ENSBTAP00000011169 Bos taurus (bovine) ENSCAFP00000021740 Canis familiaris (dog) CPIJ014419 Culex pipens (mosquito) ENSCPOP00000000911 Cavia porcellus (guinea pig) 221530 Capitella spl (polychaete worm) 299723 Daphnia pulex (daphnia) ENSDARP00000021509 Danio rerio (zebra fish) ENSDARP00000051942 Danio rerio (zebra fish) ENSECAP00000011151 Equus caballus (horse) ENSGACP00000003115 Gymnopilus aculeatus (mushroom) ENSGALP00000004139 Gallus gallus (chicken) ENSP00000376177 Homo sapiens (human) 172709 Lottia gigantea (owl limpet) ENSMODP00000013390 Monodelphis domestica (gray opossum) ENSMMUP00000012352 Macaca mulatta (rhesus monkey) ENSMUSP00000097527 Mus musculus (house mouse) XP_001601649.1 Nasonia vitripennis (wasp) ENSORLP00000018105 Oryzias latipes (japanese killifish) PHUM005412-PA Pediculus humanus (human body louse) ENSPPYP00000014533 Pongo pygmaeus (orangutan) ENSPTRP00000021750 Pan troglodytes (chimpanzee) ENSRNOP00000006462 Rattus norvegicus (norway rat) XP_969030.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011722 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000016740 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000030402 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36475 modMine - Data generated by the modENCODE project. • FBgn0052843 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB14389 NV14697 LH13022 ISCW012970 FBgn0231052 FBgn0219826 FBgn0208330 FBgn0197051 FBgn0175172 JGI_V11_299723 FBgn0077191 FBgn0148713 FBgn0142183 FBgn0127741 FBgn0114674 FBgn0088235 CPIJ014419 BGIBMGA009927 ACYPI007222 ACYPI001361 GB12975 GPRCAL1 PHUM428070 GLEAN_02694
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	anon-WO0170980.136   anon-WO0170980.137   CG17043 (Wang et al., 2004) CG17415 (Radford et al., 2002, Mertens et al., 2005, Mertens et al., 2005, Wang et al., 2004, Johnson et al., 2005, Hector et al., 2009) CG32843 (Hyun et al., 2005, Perkins et al., 1.15.2009, Cardoso et al., 2006, Keleman et al., 2009.8.5) DH31 (Kula-Eversole et al., 2010) DH31R (Kula-Eversole et al., 2010) DH31-R (Hector et al., 2009) Dh31-R1 (Kula-Eversole et al., 2010, Jumbo-Lucioni et al., 2010) DH31-R1 (Johnson et al., 2005) DmeCG32843 (Cardoso et al., 2006)
Name Synonym	CG32843   DH31 Receptor (Choi et al., 2009) DH31-receptor (Veenstra et al., 2008) DH31 receptor (Johnson et al., 2005) Diuretic hormone 31 receptor 1
Secondary FlyBase IDs
	FBgn0033824 FBgn0033825 FBgn0046596 FBgn0046597
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 3 ) Review  ( 1 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 3 ) Computer file  ( 3 ) Curated genome annotation  ( 1 ) Patent  ( 1 ) Automatic genome annotation  ( 1 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 2 )
	Jumbo-Lucioni et al., 2010, BMC Genomics 11: 297 Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. [FBrf0210956] Kula-Eversole et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(30): 13497--13502 Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila. [FBrf0211416] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...