General Information Symbol Dmel\ 4EHPSpecies D. melanogaster Name eIF4E-Homologous Protein Annotation symbol CG33100 Feature type protein_coding_gene FlyBase ID FBgn0053100 Gene Model Status Current Stock availability 26 publicly
available Also Known As d4EHP, eIF4E-8, 4E-HP Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 95E1-95E1 Sequence location 3R:19,888,799..19,934,682 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
eIF4E-Homologous Protein is referred to in FlyBase by the symbol
Dmel\4EHP (CG33100, FBgn0053100). It is a protein_coding_gene from
Drosophila melanogaster . There is experimental evidence that it has the
molecular function : protein binding; translation repressor activity; RNA 7-methylguanosine cap binding. There is experimental evidence that it is involved in the
biological process : inter-male aggressive behavior; imaginal disc-derived wing morphogenesis; negative regulation of translation; neurogenesis.
33 alleles are reported . The
phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has
4 annotated transcripts and
4 annotated polypeptides .
Protein features are: Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: larval trachea, adult ovary, adult testis. Gene sequence location is
3R:19888799..19934682 .
User Contributed Data External Summaries
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.49
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Shares 3' UTR sequences with downstream gene.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
169
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
109
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
131
head, mated 4-day male
124
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
(47)
central nervous system, pupae P8
(169)
head, virgin 1-day female
(100)
head, virgin 4-day female
(87)
head, virgin 20-day female
17
head, mated 1-day female
(109)
head, mated 4-day female
(68)
head, mated 20-day female
22
head, mated 1-day male
(131)
head, mated 4-day male
(124)
head, mated 20-day male
(67)
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
(37)
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
(74)
ovary, mated 4-day female
(85)
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
(169)
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
(109)
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
(131)
head, mated 4-day male
(124)
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
169
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
109
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
131
head, mated 4-day male
124
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
169
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
109
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
131
head, mated 4-day male
124
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
(47)
central nervous system, pupae P8
(169)
head, virgin 1-day female
(100)
head, virgin 4-day female
(87)
head, virgin 20-day female
17
head, mated 1-day female
(109)
head, mated 4-day female
(68)
head, mated 20-day female
22
head, mated 1-day male
(131)
head, mated 4-day male
(124)
head, mated 20-day male
(67)
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
(37)
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
(74)
ovary, mated 4-day female
(85)
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
(169)
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
109
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
131
head, mated 4-day male
124
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
21
central nervous system, larvae L3
47
central nervous system, pupae P8
169
head, virgin 1-day female
100
head, virgin 4-day female
87
head, virgin 20-day female
17
head, mated 1-day female
109
head, mated 4-day female
68
head, mated 20-day female
22
head, mated 1-day male
131
head, mated 4-day male
124
head, mated 20-day male
67
salivary gland, larvae L3 wandering
3
salivary gland, white prepupae
11
digestive system, larvae L3 wandering
11
digestive system, 1-day adult
9
digestive system, 4-day adult
16
digestive system, 20-day adult
9
fat body, larvae L3 wandering
4
fat body, white prepupae
11
fat body, pupae P8
37
carcass, larvae L3 wandering
17
carcass, 1-day adult
17
carcass, 4-day adult
23
carcass, 20-day adult
13
ovary, virgin 4-day female
74
ovary, mated 4-day female
85
testis, mated 4-day male
17
accessory gland, mated 4-day male
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
16
embryo 02-04hr
8
embryo 04-06hr
10
embryo 06-08hr
9
embryo 08-10hr
8
embryo 10-12hr
7
embryo 12-14hr
9
embryo 14-16hr
6
embryo 16-18hr
9
embryo 18-20hr
8
embryo 20-22hr
12
embryo 22-24hr
16
larva L1
11
larva L2
9
larva L3 12hr old
5
larva L3 puffstage 1-2
3
larva L3 puffstage 3-6
5
larva L3 puffstage 7-9
6
white prepupae new
6
white prepupae 12hr
6
white prepupae 24hr
8
pupae 2d postWPP
13
pupae 3d postWPP
12
pupae 4d postWPP
7
adult male 01day
8
adult male 05day
8
adult male 30day
7
adult female 01day
6
adult female 05day
12
adult female 30day
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
(37)
embryonic S1
11
embryonic S3
(29)
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
(28)
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
(29)
ovary fGS/OSS
25
ovary OSC
(37)
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
(37)
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
(37)
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
24
Schneider line 2 Sg4
12
embryonic 1182-4H
10
embryonic GM2
16
embryonic Kc167
37
embryonic S1
11
embryonic S3
29
leg disc CME L1
18
wing disc CME-W2
24
wing disc ML-DmD8
16
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
20
wing disc ML-DmD21
10
wing disc ML-DmD32
28
haltere disc ML-DmD17-c3
19
eye-antennal disc ML-DmD11
15
antennal disc ML-DmD20-c5
12
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
26
CNS ML-DmBG2-c2
18
tumorous blood cells mbn2
29
ovary fGS/OSS
25
ovary OSC
37
ovary OSS
18
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(32)
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
(27)
Cadmium 100 mM 48 hrs, 4-day adult
(74)
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
(100)
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
(62)
Ethanol 2.5% 3 hrs, larvae L3
(28)
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(65)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(38)
Paraquat 5 mM 48 hrs, 4-day adult
(47)
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
(74)
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
(100)
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
(62)
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(65)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(38)
Paraquat 5 mM 48 hrs, 4-day adult
(47)
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
32
cold shock, 4-day adult
24
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
7
Cadmium 50 mM 12 hrs, larvae L3
12
Cadmium 50 mM 48 hrs, 4-day adult
27
Cadmium 100 mM 48 hrs, 4-day adult
74
Copper 0.5 mM 12 hrs, larvae L3
11
Copper 15 mM 48 hrs, 4-day adult
100
Zinc 5 mM 12 hrs, larvae L3
15
Zinc 4.5 mM 48 hrs, 4-day adult
62
Ethanol 2.5% 3 hrs, larvae L3
28
Ethanol 5% 3 hrs, larvae L3
9
Ethanol 10% 3 hrs, larvae L3
8
Caffeine 1.5 mg/ml 4 hrs, larvae L3
7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
65
Caffeine 25 mg/ml 48 hrs, 4-day adult
38
Paraquat 5 mM 48 hrs, 4-day adult
47
Paraquat 10 mM 48 hrs, 4-day adult
24
Rotenone 2 μg 12 hrs, larvae L3
12
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 28 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 5 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions insertion of mobile activating element
insertion of enhancer trap
miscellaneous insertions
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
insertion of enhancer trap binary system
Gene Ontology: Function, Process
& Cellular Component ( 11 unique terms ) Terms Based on
Experimental Evidence ( 8 terms ) Molecular Function inferred from direct assay
inferred from physical interaction with
bcd inferred from physical interaction with
brat inferred from direct assay
inferred from genetic interaction with
bcd Biological Process inferred from mutant phenotype
inferred from mutant phenotype
inferred from genetic interaction with
bcd inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function inferred from sequence or structural similarity with
EMBL:AF038957 Biological Process inferred from sequence or structural similarity with
EMBL:AF038957 Cellular Component inferred from sequence or structural similarity with
EMBL:AF038957 Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (39)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG66WZVQ )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6WM53S )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG66HF6V )
Apis mellifera
Western honey bee
Amel\4EHP
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG010640
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH19644
Atta cephalotes
Leafcutter ant
Acep\ACEP16284
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO15870
Linepithema humile
Argentine ant
Lhum\LH23481
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB10924
Solenopsis invicta
Red fire ant
Sinv\SINV14953
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG61NS35 )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG67Q91P )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 26 )Harvard Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 145 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: 4EHP CG33100
Source for database merge of Additional comments Annotation CG10716 split into CG33100 and CG31136 (
Syx1A ) in release 3 of the genome annotation. In addition release 3 annotation CG31136 (
Syx1A ) contains sequences corresponding to release 2 annotation CG18615.
Other Comments brat and
4EHP interact physically and both play a role in
hb regulation.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- A cyberspace guide to Drosophila development and metazoan evolution
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 8 )Reported As Symbol Synonym 4EHP
(
Buszczak et al., 2007 ,
Zhang et al., 2007 ,
Tadros et al., 2007 ,
Ayroles et al., 2009 ,
Edwards et al., 2009 ,
Temme et al., 2010 ,
Cho et al., 2005 ,
Reis et al., 2010 ,
Carreira et al., 2011 )
CG33100
(
Hernandez et al., 2005 ,
Myrick et al., 2005.5.16 ,
Hernandez and Vazquez-Pianzola, 2005 ,
Ni et al., 2011.7.19 ,
Hazelett et al., 2009 ,
Tettweiler et al., 2012 )
d4EHP
(
Cho et al., 2005 ,
Cho et al., 2005 ,
Cho et al., 2006 ,
Okumura et al., 2007 ,
Hernandez and Vazquez-Pianzola, 2005 ,
Singh et al., 2011 ,
Yarunin et al., 2011 )
Name Synonym Secondary FlyBase
IDs References ( 49 )Generate a list of List References by type
Recent research papers ( 6 )
Hernandez et al., 2012, Development 139(17): 3211--3220Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. [FBrf0219080] Tettweiler et al., 2012, Comp. Funct. Genomics 2012: 960420The Distribution of eIF4E-Family Members across Insecta. [FBrf0218730] Weidmann and Goldstrohm, 2012, Mol. Cell. Biol. 32(2): 527--540Drosophila Pumilio Protein Contains Multiple Autonomous Repression Domains That Regulate mRNAs Independently of Nanos and Brain Tumor. [FBrf0217089] Carreira et al., 2011, BMC Dev. Biol. 11: 32Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Singh et al., 2011, Dev. Biol. 352(1): 104--115The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo. [FBrf0213172] Yarunin et al., 2011, RNA Biol. 8(5): 904--912Patterning of the Drosophila oocyte by a sequential translation repression program involving the d4EHP and Belle translational repressors. [FBrf0217939]
Recent reviews (0)
All reviews listed in FlyBase were published before 2011