General Information Symbol Dmel\ p24-2Species D. melanogaster Name p24-related-2 Annotation symbol CG33105 Feature type protein_coding_gene FlyBase ID FBgn0053105 Gene Model Status Current Stock availability None publicly available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 85E4-85E4 Sequence location 3R:5,513,124..5,518,516 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
p24-related-2 is referred to in FlyBase by the symbol
Dmel\p24-2 (CG33105, FBgn0053105). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. There is experimental evidence that it is involved in the
biological process : regulation of post-mating oviposition; reproduction.
3 alleles are reported . No phenotypic data is available. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: GOLD. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult salivary gland. Comments on Affy2 ProbeSet: ProbeSet 1625153_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of p24-2 expression signal. See the GBrowse view of p24-2 to determine the overlapping gene(s). Gene sequence location is
3R:5513124..5518516 .
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.49
gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
13.35
Larval Midgut
43.3
Larval Hindgut
24.9
Larval Malpighian Tubules
28.4
Larval Fat Body
36.2
Larval Salivary Gland
74.2
Larval Trachea
12.7
Larval Carcass
23.775
Adult Head
12.8
Adult Eye
12.75
Adult Brain
17.9
Adult Thoracic-Abdominal Ganglion
16.6
Adult Crop
20.6
Adult Midgut
46.2
Adult Hindgut
19.7
Adult Malpighian Tubules
12.3
Adult Fat Body
27.6
Adult Salivary Gland
184
Adult Heart
15.875
Adult VirginFemale Spermatheca
18.3
Adult InseminatedFemale Spermatheca
23
Adult Ovary
7.4
Adult Testis
7.5
Adult Male Accessory Gland
73.6
Adult Carcass
36.8
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
no informative data
NA
Eye
no informative data
NA
Brain
17.9
13.35
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
no informative data
NA
Crop
20.6
43.3
Midgut
46.2
24.9
Hindgut
19.7
28.4
Malpighian Tubules
no informative data
36.2
Fat Body
no informative data
74.2
Salivary Gland
184
NA
Heart
no informative data
no informative data
Trachea
NA
NA
VirginFemale Spermatheca
no informative data
NA
InseminatedFemale Spermatheca
23
NA
Ovary
7.4
NA
Testis
7.5
NA
Male Accessory Gland
73.6
no informative data
Carcass
36.8
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
16
central nervous system, larvae L3
15
central nervous system, pupae P8
13
head, virgin 1-day female
9
head, virgin 4-day female
8
head, virgin 20-day female
8
head, mated 1-day female
8
head, mated 4-day female
9
head, mated 20-day female
7
head, mated 1-day male
11
head, mated 4-day male
11
head, mated 20-day male
12
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
9
digestive system, larvae L3 wandering
9
digestive system, 1-day adult
17
digestive system, 4-day adult
17
digestive system, 20-day adult
20
fat body, larvae L3 wandering
6
fat body, white prepupae
5
fat body, pupae P8
12
carcass, larvae L3 wandering
12
carcass, 1-day adult
7
carcass, 4-day adult
9
carcass, 20-day adult
8
ovary, virgin 4-day female
4
ovary, mated 4-day female
3
testis, mated 4-day male
23
accessory gland, mated 4-day male
16
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
(29)
embryo 10-12hr
(37)
embryo 12-14hr
(27)
embryo 14-16hr
(31)
embryo 16-18hr
(28)
embryo 18-20hr
(33)
embryo 20-22hr
(62)
embryo 22-24hr
(30)
larva L1
(40)
larva L2
(32)
larva L3 12hr old
(47)
larva L3 puffstage 1-2
(28)
larva L3 puffstage 3-6
(34)
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
(43)
white prepupae 24hr
(32)
pupae 2d postWPP
(27)
pupae 3d postWPP
12
pupae 4d postWPP
(28)
adult male 01day
26
adult male 05day
(72)
adult male 30day
21
adult female 01day
22
adult female 05day
(27)
adult female 30day
(33)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
(37)
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
(33)
embryo 20-22hr
(62)
embryo 22-24hr
30
larva L1
(40)
larva L2
32
larva L3 12hr old
(47)
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
(34)
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
(43)
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
(72)
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
(33)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
10
embryo 02-04hr
16
embryo 04-06hr
9
embryo 06-08hr
17
embryo 08-10hr
29
embryo 10-12hr
37
embryo 12-14hr
27
embryo 14-16hr
31
embryo 16-18hr
28
embryo 18-20hr
33
embryo 20-22hr
62
embryo 22-24hr
30
larva L1
40
larva L2
32
larva L3 12hr old
47
larva L3 puffstage 1-2
28
larva L3 puffstage 3-6
34
larva L3 puffstage 7-9
22
white prepupae new
17
white prepupae 12hr
43
white prepupae 24hr
32
pupae 2d postWPP
27
pupae 3d postWPP
12
pupae 4d postWPP
28
adult male 01day
26
adult male 05day
72
adult male 30day
21
adult female 01day
22
adult female 05day
27
adult female 30day
33
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(36)
Schneider line 2 Sg4
(68)
embryonic 1182-4H
(32)
embryonic GM2
(30)
embryonic Kc167
10
embryonic S1
(83)
embryonic S3
(94)
leg disc CME L1
(53)
wing disc CME-W2
26
wing disc ML-DmD8
(41)
wing disc ML-DmD9
(41)
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
(33)
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
(48)
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(36)
Schneider line 2 Sg4
(68)
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
(83)
embryonic S3
(94)
leg disc CME L1
(53)
wing disc CME-W2
26
wing disc ML-DmD8
(41)
wing disc ML-DmD9
(41)
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
(33)
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
(48)
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
36
Schneider line 2 Sg4
68
embryonic 1182-4H
32
embryonic GM2
30
embryonic Kc167
10
embryonic S1
83
embryonic S3
94
leg disc CME L1
53
wing disc CME-W2
26
wing disc ML-DmD8
41
wing disc ML-DmD9
41
wing disc ML-DmD16-c3
11
wing disc ML-DmD21
25
wing disc ML-DmD32
33
haltere disc ML-DmD17-c3
15
eye-antennal disc ML-DmD11
18
antennal disc ML-DmD20-c5
20
mixed discs ML-DmD4-c1
13
CNS ML-DmBG1-c1
15
CNS ML-DmBG2-c2
6
tumorous blood cells mbn2
48
ovary fGS/OSS
19
ovary OSC
16
ovary OSS
10
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
10
cold shock, 4-day adult
8
heat shock, 4-day adult
19
Cadmium 50 mM 6 hrs, larvae L3
21
Cadmium 50 mM 12 hrs, larvae L3
11
Cadmium 50 mM 48 hrs, 4-day adult
16
Cadmium 100 mM 48 hrs, 4-day adult
8
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
11
Zinc 4.5 mM 48 hrs, 4-day adult
7
Ethanol 2.5% 3 hrs, larvae L3
15
Ethanol 5% 3 hrs, larvae L3
17
Ethanol 10% 3 hrs, larvae L3
20
Caffeine 1.5 mg/ml 4 hrs, larvae L3
14
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
7
Caffeine 25 mg/ml 48 hrs, 4-day adult
7
Paraquat 5 mM 48 hrs, 4-day adult
11
Paraquat 10 mM 48 hrs, 4-day adult
18
Rotenone 2 μg 12 hrs, larvae L3
17
Rotenone 8 μg 12 hrs, larvae L3
21
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 2 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 1 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 5 unique terms ) Terms Based on
Experimental Evidence ( 2 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function ( 0 terms) Biological Process Cellular Component inferred from sequence or structural similarity with
EMBL:X90872 Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (49)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG65MNRN )
Drosophila melanogaster
fruit fly
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6NP7CJ )
Aedes aegypti
Yellow fever mosquito
Y
Anopheles gambiae
Malaria mosquito
Y
Culex quinquefasciatus
Southern house mosquito
Y
Orthologs in non-Dipteran Insects
(EOG6NP60Q )
Apis mellifera
Western honey bee
Amel\LOC412554
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG008131
Y
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH15237
Y
Atta cephalotes
Leafcutter ant
Acep\ACEP19202
Y
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO18063
Y
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL23718
Y
Linepithema humile
Argentine ant
Lhum\LH20419
Y
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB24313
Y
Solenopsis invicta
Red fire ant
Sinv\SINV10826
Y
Acyrthosiphon pisum
Pea aphid
Y
Pediculus humanus
Human body louse
Y
Tribolium castaneum
Red flour beetle
Y
Orthologs in non-Insect Arthropods
(EOG6SBCF4 )
Daphnia pulex
Water flea
Y
Ixodes scapularis
Deer tick
Y
Orthologs in non-Arthropod Metazoa
(EOG66HV5F )
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (2)AAA Orthologs (0)
based on analysis using Dmel annotation version 4.3
Stocks & Reagents Stocks Listed in FlyBase ( 0 ) Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 283 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: p24-2 CG33105
Source for database merge of Additional comments One or more of the processed
transcripts for these genes contain two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG31332 (
FBgn0260463 ), CG33105 (
FBgn0053105 ).
Annotation CG9443 split into CG33104, CG33105 in release 3 of the genome annotation.
Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 5 )Reported As Symbol Synonym CG33105
(
Carney and Bowen, 2004 ,
Boltz et al., 2007 ,
Vinci et al., 2008 ,
Zhan et al., 2011 ,
Keleman et al., 2009.8.5 ,
Chen et al., 2010 ,
Chen et al., 2010 ,
Port et al., 2011 )
Name Synonym Secondary FlyBase
IDs References ( 22 )Generate a list of List References by type
Recent research papers ( 4 )
Saleem et al., 2012, Mech. Dev. 129(5-8): 177--191Drosophila melanogaster p24 trafficking proteins have vital roles in development and reproduction. [FBrf0219054] Ou et al., 2011, PLoS Biol. 9(9): e1001160Nuclear Receptor DHR4 Controls the Timing of Steroid Hormone Pulses During Drosophila Development. [FBrf0216318] Port et al., 2011, EMBO Rep. 12(11): 1144--1152A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. [FBrf0216532] Zhan et al., 2011, Gene 470(1-2): 1--6Evolution of alternative splicing in newly evolved genes of Drosophila. [FBrf0212278]
Recent reviews (0)
All reviews listed in FlyBase were published before 2011