FB2020_06, released Dec 22, 2020

Gene: Dmel\CG33110

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General Information
Symbol
Dmel\CG33110
Species
D. melanogaster
Name
Annotation Symbol
CG33110
Feature Type
protein_coding_gene
FlyBase ID
FBgn0053110
Gene Model Status
Current
Stock Availability
6 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
94B4-94B4
Sequence location
3R:22,570,188..22,580,392 [+]
Recombination map

3-75

RefSeq locus
NT_033777 REGION:22570188..22580392
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (8 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables fatty acid elongase activity
inferred from sequence or structural similarity with FLYBASE:bond; FB:FBgn0260942
(Szafer-Glusman et al., 2008)
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (6 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (6 terms)
CV Term
Evidence
References
involved_in fatty acid elongation, monounsaturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in fatty acid elongation, polyunsaturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in fatty acid elongation, saturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in fatty acid elongation
inferred from sequence or structural similarity with FLYBASE:bond; FB:FBgn0260942
(Szafer-Glusman et al., 2008)
involved_in sphingolipid biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in very long-chain fatty acid biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in integral component of endoplasmic reticulum membrane
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
FATTY ACID ELONGASES -
Fatty acid elongases are conserved from yeast to mammals and mediate elongation of fatty acids into very-long-chain fatty acids (VLCFAs, i.e. with acyl chains of 18 carbon atoms or longer). They are bound to the endoplasmic reticulum membrane where they are believed to perform the first step (condensation) in the elongation cycle. VLCFAs are most commonly found in sphingolipids and are essential for sphingolipid formation and function. (Adapted from PMID:16564093.)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\CG33110 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
CG33110-RA
FBtr0084264
NM_176539
2005
337
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
CG33110-PA
FBpp0083657
39.9
337
9.42
NP_788716
AAF56020
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG33110 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
expression microarray
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult fat body

Comment: cyclical, peak ZT9-12

(Xu et al., 2011)
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 13 -- 16
embryonic large intestine
(Fisher et al., 2012)
Additional Descriptive Data

Expressed cyclically in the adult fat body.

(Xu et al., 2011)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\CG33110 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 4 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of CG33110
Transgenic constructs containing regulatory region of CG33110
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4Mef2.PR
Other Phenotypes
Allele
some die during pupal stage, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (7)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ELOVL1
7 of 15
Yes
No
1  
Hsap\ELOVL7
6 of 15
No
No
Hsap\ELOVL2
3 of 15
No
No
Hsap\ELOVL4
3 of 15
No
No
Hsap\ELOVL5
3 of 15
No
No
Hsap\ELOVL3
2 of 15
No
No
Hsap\ELOVL6
2 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (7)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Elovl1
7 of 15
Yes
No
Mmus\Elovl7
6 of 15
No
No
Mmus\Elovl2
3 of 15
No
No
Mmus\Elovl4
3 of 15
No
No
Mmus\Elovl5
3 of 15
No
No
Mmus\Elovl3
2 of 15
No
No
Mmus\Elovl6
1 of 15
No
No
Rattus norvegicus (Norway rat) (8)
Rnor\Elovl1
6 of 13
Yes
No
Rnor\Elovl7
6 of 13
Yes
No
Rnor\Elovl2
3 of 13
No
No
Rnor\Elovl4
3 of 13
No
No
Rnor\Elovl5
3 of 13
No
No
Rnor\Elovl3
2 of 13
No
No
Rnor\LOC102549542
2 of 13
No
No
Rnor\Elovl6
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (10)
Xtro\elovl1
6 of 12
Yes
No
Xtro\elovl7
5 of 12
No
No
Xtro\elovl2
3 of 12
No
No
Xtro\elovl5
3 of 12
No
No
Xtro\elovl3
2 of 12
No
No
Xtro\elovl4
2 of 12
No
No
Xtro\elovl6
2 of 12
No
No
Xtro\LOC101732387
2 of 12
No
Yes
Xtro\LOC101733189
2 of 12
No
Yes
Xtro\LOC101731836
1 of 12
No
No
Danio rerio (Zebrafish) (13)
Drer\elovl1b
7 of 15
Yes
No
Drer\elovl7a
7 of 15
Yes
No
Drer\elovl7b
7 of 15
Yes
No
Drer\elovl1a
6 of 15
No
No
Drer\elovl2
3 of 15
No
No
Drer\elovl4a
3 of 15
No
No
Drer\elovl4b
3 of 15
No
No
Drer\elovl5
3 of 15
No
No
Drer\elovl8a
3 of 15
No
No
Drer\elovl8b
3 of 15
No
No
Drer\elovl6
2 of 15
No
No
Drer\elovl6l
2 of 15
No
No
Drer\zgc:92749
2 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (9)
Cele\elo-1
2 of 15
Yes
No
Cele\elo-2
2 of 15
Yes
No
Cele\elo-3
2 of 15
Yes
No
Cele\elo-4
2 of 15
Yes
No
Cele\elo-5
2 of 15
Yes
No
Cele\elo-6
2 of 15
Yes
No
Cele\elo-7
2 of 15
Yes
No
Cele\elo-8
2 of 15
Yes
No
Cele\elo-9
2 of 15
Yes
No
Arabidopsis thaliana (thale-cress) (4)
Atha\AT3G06460
3 of 9
Yes
No
Atha\AT3G06470
3 of 9
Yes
No
Atha\HOS3-1
2 of 9
No
No
Atha\AT1G75000
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\ELO2
5 of 15
Yes
No
Scer\ELO1
4 of 15
No
No
Scer\ELO3
4 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPAC1B2.03c
3 of 12
Yes
No
Spom\SPAC1639.01c
2 of 12
No
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190BDF )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00011769
Drosophila simulans
Dsim\GD20963
Drosophila sechellia
Dsec\GM26444
Drosophila erecta
Dere\GG11146
Drosophila yakuba
Dyak\GE10311
Drosophila ananassae
Dana\GF18859
Drosophila pseudoobscura pseudoobscura
Dpse\GA26807
Drosophila persimilis
Dper\GL13810
Drosophila willistoni
Dwil\GK12818
Drosophila virilis
Dvir\GJ24167
Drosophila mojavensis
Dmoj\GI23311
Drosophila grimshawi
Dgri\GH18331
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915072M )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17025025
Glossina morsitans
Tsetse fly
Gmor\GMOY008581
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_11742
Mayetiola destructor
Hessian fly
Mdes\Mdes000404
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012497
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL003093
Anopheles darlingi
American malaria mosquito
Adar\ADAC000004
Anopheles darlingi
American malaria mosquito
Adar\ADAC003322
Anopheles gambiae
Malaria mosquito
Agam\AGAP011848
Anopheles gambiae
Malaria mosquito
Agam\AGAP007134
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ001449
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ003687
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W07AR )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA010923
Danaus plexippus
Monarch butterfly
Dple\DPOGS209920-PA
Apis florea
Little honeybee
Aflo\2346876100
Apis mellifera
Western honey bee
Amel\LOC724867
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP20095
Bombus terrestris
Buff-tailed bumblebee
Bter\15205908
Linepithema humile
Argentine ant
Lhum\LH17396
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00067b
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG018110
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11598
Tribolium castaneum
Red flour beetle
Tcas\TC034275
Pediculus humanus
Human body louse
Phum\PHUM047430
Rhodnius prolixus
Kissing bug
Rpro\RPRC003666
Cimex lectularius
Bed bug
Clec\CLEC008442
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI083009
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_07408
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0A3S )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR002556
Strigamia maritima
European centipede
Smar\SMAR002349
Strigamia maritima
European centipede
Smar\SMAR001835
Strigamia maritima
European centipede
Smar\SMAR013293
Strigamia maritima
European centipede
Smar\SMAR002560
Strigamia maritima
European centipede
Smar\SMAR002261
Ixodes scapularis
Black-legged tick
Isca\ISCW003063
Ixodes scapularis
Black-legged tick
Isca\ISCW002252
Ixodes scapularis
Black-legged tick
Isca\ISCW005940
Ixodes scapularis
Black-legged tick
Isca\ISCW015231
Ixodes scapularis
Black-legged tick
Isca\ISCW001194
Ixodes scapularis
Black-legged tick
Isca\ISCW015232
Ixodes scapularis
Black-legged tick
Isca\ISCW001195
Ixodes scapularis
Black-legged tick
Isca\ISCW002256
Ixodes scapularis
Black-legged tick
Isca\ISCW015224
Ixodes scapularis
Black-legged tick
Isca\ISCW011553
Ixodes scapularis
Black-legged tick
Isca\ISCW019368
Ixodes scapularis
Black-legged tick
Isca\ISCW015228
Ixodes scapularis
Black-legged tick
Isca\ISCW015239
Ixodes scapularis
Black-legged tick
Isca\ISCW015237
Ixodes scapularis
Black-legged tick
Isca\ISCW015226
Ixodes scapularis
Black-legged tick
Isca\ISCW013893
Ixodes scapularis
Black-legged tick
Isca\ISCW002250
Ixodes scapularis
Black-legged tick
Isca\ISCW023546
Ixodes scapularis
Black-legged tick
Isca\ISCW022846
Ixodes scapularis
Black-legged tick
Isca\ISCW003894
Ixodes scapularis
Black-legged tick
Isca\ISCW017055
Ixodes scapularis
Black-legged tick
Isca\ISCW003066
Ixodes scapularis
Black-legged tick
Isca\ISCW017283
Ixodes scapularis
Black-legged tick
Isca\ISCW015230
Ixodes scapularis
Black-legged tick
Isca\ISCW009915
Ixodes scapularis
Black-legged tick
Isca\ISCW019366
Ixodes scapularis
Black-legged tick
Isca\ISCW012517
Ixodes scapularis
Black-legged tick
Isca\ISCW023550
Ixodes scapularis
Black-legged tick
Isca\ISCW015238
Ixodes scapularis
Black-legged tick
Isca\ISCW010899
Ixodes scapularis
Black-legged tick
Isca\ISCW019367
Ixodes scapularis
Black-legged tick
Isca\ISCW019365
Ixodes scapularis
Black-legged tick
Isca\ISCW013892
Ixodes scapularis
Black-legged tick
Isca\ISCW003067
Ixodes scapularis
Black-legged tick
Isca\ISCW010858
Ixodes scapularis
Black-legged tick
Isca\ISCW015056
Ixodes scapularis
Black-legged tick
Isca\ISCW003062
Ixodes scapularis
Black-legged tick
Isca\ISCW003068
Ixodes scapularis
Black-legged tick
Isca\ISCW010886
Ixodes scapularis
Black-legged tick
Isca\ISCW010647
Ixodes scapularis
Black-legged tick
Isca\ISCW015227
Ixodes scapularis
Black-legged tick
Isca\ISCW002253
Ixodes scapularis
Black-legged tick
Isca\ISCW015235
Ixodes scapularis
Black-legged tick
Isca\ISCW015233
Ixodes scapularis
Black-legged tick
Isca\ISCW015236
Stegodyphus mimosarum
African social velvet spider
Smim\KFM74785.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM82890.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM65625.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM82810.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79053.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79273.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79270.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70965.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM73200.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79268.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g06470
Tetranychus urticae
Two-spotted spider mite
Turt\tetur04g04190
Tetranychus urticae
Two-spotted spider mite
Turt\tetur04g09500
Tetranychus urticae
Two-spotted spider mite
Turt\tetur02g08130
Tetranychus urticae
Two-spotted spider mite
Turt\tetur09g01270
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g03780
Tetranychus urticae
Two-spotted spider mite
Turt\tetur03g09190
Tetranychus urticae
Two-spotted spider mite
Turt\tetur34g00930
Tetranychus urticae
Two-spotted spider mite
Turt\tetur05g03200
Tetranychus urticae
Two-spotted spider mite
Turt\tetur28g00900
Tetranychus urticae
Two-spotted spider mite
Turt\tetur15g02930
Tetranychus urticae
Two-spotted spider mite
Turt\tetur04g04230
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_324296
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_307269
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_324294
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_48753
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_307239
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_307240
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_322487
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_108808
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_307270
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_214082
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_41788
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_41014
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_307241
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_128564
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0N2V )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Hsd17b8
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_024642gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Sdr_3
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Elovl7
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Elovl4
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Elovl4_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Dhrs7
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Elovl7L
Ciona intestinalis
Vase tunicate
Cint\elo
Ciona intestinalis
Vase tunicate
Cint\LOC100181604
Ciona intestinalis
Vase tunicate
Cint\LOC100184237
Ciona intestinalis
Vase tunicate
Cint\LOC100184861
Ciona intestinalis
Vase tunicate
Cint\LOC100176701
Ciona intestinalis
Vase tunicate
Cint\LOC100177165
Ciona intestinalis
Vase tunicate
Cint\LOC100180120
Ciona intestinalis
Vase tunicate
Cint\LOC100182495
Gallus gallus
Domestic chicken
Ggal\ELOVL7
Gallus gallus
Domestic chicken
Ggal\DHRS7
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000009714
Gallus gallus
Domestic chicken
Ggal\ELOVL2
Gallus gallus
Domestic chicken
Ggal\ELOVL4
Gallus gallus
Domestic chicken
Ggal\ELOVL5
Gallus gallus
Domestic chicken
Ggal\ELOVL1
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (21)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
eloF
7 of 10
bond
6 of 10
CG5326
6 of 10
CG6660
6 of 10
CG8534
6 of 10
CG9458
6 of 10
CG9459
6 of 10
CG16904
6 of 10
CG17821
6 of 10
CG18609
6 of 10
CG30008
6 of 10
CG31141
6 of 10
CG31522
6 of 10
Elo68α
6 of 10
Elo68β
6 of 10
Elovl7
6 of 10
sit
6 of 10
Baldspot
5 of 10
CG31523
5 of 10
CG32071
1 of 10
tea
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ELOVL1; ELOVL fatty acid elongase 1
    7 of 15
    611813
       
      ELOVL7; ELOVL fatty acid elongase 7
      6 of 15
      614451
          ELOVL2; ELOVL fatty acid elongase 2
          3 of 15
          611814
              ELOVL4; ELOVL fatty acid elongase 4
              3 of 15
              605512
              ELOVL5; ELOVL fatty acid elongase 5
              3 of 15
              611805
              Functional Complementation Data
              Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
              Interactions
              Summary of Physical Interactions
              esyN Network Diagram
              Interactions Browser
              Summary of Genetic Interactions
              esyN Network Diagram
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              External Data
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Pathways
              Signaling Pathways (FlyBase)
              Metabolic Pathways
              External Data
              Linkouts
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Genomic Location and Detailed Mapping Data
              Chromosome (arm)
              3R
              Recombination map

              3-75

              Cytogenetic map
              94B4-94B4
              Sequence location
              3R:22,570,188..22,580,392 [+]
              FlyBase Computed Cytological Location
              Cytogenetic map
              Evidence for location
              94B4-94B4
              Limits computationally determined from genome sequence between P{PZ}l(3)rQ178rQ178 and P{lacW}Dph5L4910
              Experimentally Determined Cytological Location
              Cytogenetic map
              Notes
              References
              Experimentally Determined Recombination Data
              Location

              3-75

              (FlyBase, 2016)

              3-77.7

              (Comeron et al., 2012)
              Left of (cM)
              Right of (cM)
              Notes
              Stocks and Reagents
              Stocks (6)
              Genomic Clones (25)
              cDNA Clones (48)
               

              Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

              cDNA clones, fully sequenced
              BDGP DGC clones
              Other clones
              Drosophila Genomics Resource Center cDNA clones

              For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of
              Source for database merge of

              Source for merge of: CG6926 CG13844

              (FlyBase Genome Annotators, 2002-2003)
              Additional comments

              Annotations CG6926 and CG13844 merged as CG33110 in release 3 of the genome annotation.

              (FlyBase Genome Annotators, 2002-2003)
              Other Comments

              RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.

              (Boutros et al., 2004)
              Origin and Etymology
              Discoverer
              Etymology
              Identification
              External Crossreferences and Linkouts ( 33 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              modMine - A data warehouse for the modENCODE project
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FLIGHT - Cell culture data for RNAi and other high-throughput technologies
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyMine - An integrated database for Drosophila genomics
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Synonyms and Secondary IDs (3)
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (40)