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Gene Dmel\Kdm4B

General Information
Symbol	Dmel\Kdm4B	Species	D. melanogaster
Name	Histone demethylase 4B	Annotation symbol	CG33182
Feature type	protein_coding_gene	FlyBase ID	FBgn0053182
Gene Model Status	Current	Stock availability	9 publicly available
Also Known As	dKDM4B
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	49F7-49F7	Sequence location	2R:9,063,599..9,085,842 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Histone demethylase 4B is referred to in FlyBase by the symbol Dmel\Kdm4B (CG33182, FBgn0053182). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process: histone H3-K36 demethylation; histone H3-K9 demethylation. 11 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: JmjC domain; Transcription factor jumonji, JmjN. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1629788_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of Kdm4B. Gene sequence location is 2R:9063599..9085842.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 49F7-49F7   Limits computationally determined from genome sequence between P{EP}EP873EP873 and P{EP}CG33182EP728&P{lacW}Aats-valk14804
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Kdm4B for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Shares 5' UTR with downstream gene. Gene model reviewed during 5.43 Certain protein isoforms of two separate genes, Kdm4B and seq, share 131 residues. Low-frequency RNA-Seq exon junction(s) not annotated. gene_with_dicistronic_mRNA ; SO:0000722 Exons of Kdm4B, seq and CG17724 overlap. Genes with CDS overlap: minor isoform of Kdm4B appears to share coding sequence with seq (terminal coding exon of Kdm4B and initial coding exon of seq). Other Kdm4B isoforms are highly conserved; seq orthologs not found outside Drosophila.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Kdm4B-RA FBtr0087770  NM_176164   2184   590 Kdm4B-RB FBtr0302052  NM_001169666   2225   590 Kdm4B-RC FBtr0302053  NM_001169667   2585   590 Kdm4B-RD FBtr0302054  NM_001169668   2667   590 Kdm4B-RE FBtr0310498  NM_001274013   6177   717
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Kdm4B-PA   FBpp0086883   66.4   590   7.51     NP_788344   AAF58413 Kdm4B-PB   FBpp0291262   66.4   590   7.51     NP_001163137   ACZ94410 Kdm4B-PC   FBpp0291263   66.4   590   7.51     NP_001163138   ACZ94411 Kdm4B-PD   FBpp0291264   66.4   590   7.51     NP_001163139   ACZ94412 Kdm4B-PE   FBpp0302636   80.4   717   8.07     NP_001260942   AGB93475
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • JmjC domain (IPR003347) Transcription factor jumonji, JmjN (IPR003349)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246536   AA263922   AA391310   AA440599   AA539303   AA817062   AE013599 AAF58413   AE013599 ACZ94410   AE013599 ACZ94411   AE013599 ACZ94412   AE013599 AGB93475   AI405501   AI455233   AI513470   AI515565   AI516360   AI543756   AY060442   AY070882   BE976643   BF489532   BF489542   BF489897   BF493833   BF505385   BG637946   BG640032   BI231706   BI232449   BI375746   BP553875   BP553876   BT003592   BT030245   BT030821   BT082008   BT132648   BT132685   CK131840   CK133364   CL844353   CO186421   CO191174   CO193908   CO265374   CO267986   CO268982   CO273707   CO280980   CO283113   CO296013   CO304872   CO310205   CO312296   CO315029   CO316569   CO323723   CO332262   CO341489   CZ468544   EC077188   EC078393   EC079249   EC087495   EC088425   EC198834   EC201295   EC204432   EC208580   EC210502   EC217405   EC217621   EC219889   EC220858   EC234098   EC236168   EC236735   EC246296   EC249845   EC250715   EC254746   EC256217   EL869846   EL869847   EL869848   EL869849   EL872850   EL886843   EL886905   EL887096   ES690994   EV576438   EV577514   EV578253   EV578838   EV579096   GH749101   GH755207   GH770296   GH780640   GH784807   GH803283   GH803597   GH808482   GH809064   GH809302   GH813651   GH817994   GH822668   GH824462   GH832521   GH833044   GH834692   GH851338   GH851878   GH861249   GH870108   GH870786   GH871905   GH884986   GH887631   GH896486   GH911871   GH919012   GH921719   GH925783   GH941631   GH946726   GH951165   GH953902   GH956216   GH957052   GH964818   GH965051   GH969018   GH971333   GH972314   GH975478   GH976954   GH977183   GH981161   GH984181
UniProtKB/Swiss-Prot	Q9V6L0
UniProtKB/TrEMBL	E1JH52
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    61.925 Larval Midgut    8.1 Larval Hindgut    6.8 Larval Malpighian Tubules    11.9 Larval Fat Body    31.7 Larval Salivary Gland    6.3 Larval Trachea    23.6 Larval Carcass    1.05 Adult Head    19.2 Adult Eye    46.875 Adult Brain    122.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    21.2 Adult Midgut    32.9 Adult Hindgut    14.6 Adult Malpighian Tubules    32.5 Adult Fat Body    2.2 Adult Salivary Gland    8.5 Adult Heart    22.15 Adult VirginFemale Spermatheca    5.3 Adult InseminatedFemale Spermatheca    4.9 Adult Ovary    24.8 Adult Testis    168.3 Adult Male Accessory Gland    6.1 Adult Carcass    1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    46.875   NA  Brain    122.9   61.925  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    57.1   NA  Crop    no informative data   8.1  Midgut    no informative data   6.8  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    2.2   6.3  Salivary Gland    8.5   NA  Heart    22.15   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    5.3   NA  InseminatedFemale Spermatheca    4.9   NA  Ovary    24.8   NA  Testis    168.3   NA  Male Accessory Gland    6.1   1.05  Carcass    1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (35) central nervous system, larvae L3  (102) central nervous system, pupae P8  (36) head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female  (42) ovary, mated 4-day female  (42) testis, mated 4-day male  (27) accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3  102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (35) central nervous system, larvae L3  (102) central nervous system, pupae P8  (36) head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female  (42) ovary, mated 4-day female  (42) testis, mated 4-day male  27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3  102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    102 central nervous system, pupae P8    36 head, virgin 1-day female    16 head, virgin 4-day female    19 head, virgin 20-day female    11 head, mated 1-day female    19 head, mated 4-day female    15 head, mated 20-day female    13 head, mated 1-day male    25 head, mated 4-day male    25 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    9 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    9 digestive system, 4-day adult    16 digestive system, 20-day adult    18 fat body, larvae L3 wandering    6 fat body, white prepupae    14 fat body, pupae P8    10 carcass, larvae L3 wandering    22 carcass, 1-day adult    6 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    42 ovary, mated 4-day female    42 testis, mated 4-day male    27 accessory gland, mated 4-day male    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (38) embryo 02-04hr  (37) embryo 04-06hr  (45) embryo 06-08hr  (67) embryo 08-10hr  (51) embryo 10-12hr  (28) embryo 12-14hr  (32) embryo 14-16hr  (28) embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (38) embryo 02-04hr  (37) embryo 04-06hr  (45) embryo 06-08hr  (67) embryo 08-10hr  (51) embryo 10-12hr  28 embryo 12-14hr  32 embryo 14-16hr  28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    38 embryo 02-04hr    37 embryo 04-06hr    45 embryo 06-08hr    67 embryo 08-10hr    51 embryo 10-12hr    28 embryo 12-14hr    32 embryo 14-16hr    28 embryo 16-18hr    22 embryo 18-20hr    16 embryo 20-22hr    24 embryo 22-24hr    21 larva L1    9 larva L2    6 larva L3 12hr old    6 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    14 larva L3 puffstage 7-9    16 white prepupae new    16 white prepupae 12hr    19 white prepupae 24hr    22 pupae 2d postWPP    16 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    12 adult male 05day    17 adult male 30day    18 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS  (41) ovary OSC  (59) ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS  (41) ovary OSC  (59) ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    20 Schneider line 2 Sg4    9 embryonic 1182-4H    16 embryonic GM2    20 embryonic Kc167    25 embryonic S1    22 embryonic S3    21 leg disc CME L1    17 wing disc CME-W2    14 wing disc ML-DmD8    18 wing disc ML-DmD9    14 wing disc ML-DmD16-c3    19 wing disc ML-DmD21    6 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    11 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    21 CNS ML-DmBG2-c2    22 tumorous blood cells mbn2    20 ovary fGS/OSS    41 ovary OSC    59 ovary OSS    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult  (35) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3  26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (27) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult  (35) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  (36) Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3  26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    21 cold shock, 4-day adult    16 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    35 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    36 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    4 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    25 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053182 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33182-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Kdm4BEY10737 Sterility Allele fertile Kdm4BEY10737 Other Phenotypes Allele radiation sensitive | dominant Kdm4B03531 Phenotype manifest in Allele
Classical Alleles ( 7 )
For All Classical Alleles Show
Allele of Kdm4B Class Mutagen Stocks Known lesion Kdm4BNP2264 2 -- Kdm4B03531 P-element activity 1 Yes Kdm4Bc03262 piggyBac transposase 1 -- Kdm4BEY10737 P-element activity 1 Yes Kdm4BKG08629 1 -- Kdm4BNP0792 1 -- Kdm4BEP728 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Kdm4B Class Mutagen Stocks Known lesion Kdm4BGD16017 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Kdm4BGLV21041 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Kdm4BKK102089 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Kdm4BNIG.4037R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK102089} NA P{NIG.4037R} NA P{TRiP.GLV21041} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Kdm4BEP728 NA P{EPgy2}Kdm4BEY10737 NA insertion of enhancer trap P{PZ}Aats-val03531 No miscellaneous insertions P{SUPor-P}Kdm4BKG08629 NA PBac{PB}Kdm4Bc03262 NA insertion of enhancer trap binary system P{GawB}Kdm4BNP0792 No P{GawB}Kdm4BNP2264 No
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
histone demethylase activity (H3-K9 specific) inferred from direct assay (Lin et al., 2008) inferred from mutant phenotype (Lloret-Llinares et al., 2008) histone demethylase activity (H3-K36 specific) inferred from direct assay (Lin et al., 2008) inferred from mutant phenotype (Lloret-Llinares et al., 2008)
Biological Process
CV term Evidence References
histone H3-K9 demethylation inferred from direct assay (Lin et al., 2008) inferred from mutant phenotype (Lloret-Llinares et al., 2008) histone H3-K36 demethylation inferred from mutant phenotype (Lloret-Llinares et al., 2008)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
histone demethylase activity (H3-K36 specific) inferred from sequence or structural similarity with UniProtKB:O75164 (assigned by UniProtKB) (UniProtKB Project Members, 2006.5.16)
Biological Process
CV term Evidence References
histone demethylation inferred from sequence or structural similarity with UniProtKB:O75164 (assigned by UniProtKB) (UniProtKB Project Members, 2006.5.16)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:O75164 (assigned by UniProtKB) (UniProtKB Project Members, 2006.5.16)
Sequence Ontology: Class of Gene
	gene_with_dicistronic_mRNA (FlyBase Genome Annotators, 2012) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Kdm4B allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0053182 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 318918
Orthologs
OrthoDB Orthologs (62) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6549J8 Dipteran inclusive ortholog search EOG6PG687 Insect inclusive ortholog search EOG68SFP8 Arthropod inclusive ortholog search EOG669P90 Metazoa inclusive ortholog search EOG6PP98Q
Orthologs in Drosophila Species (EOG6549J8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Kdm4B     Drosophila sechellia   Dsec\GM20306 Y   Drosophila erecta   Dere\GG22520 Y   Drosophila yakuba   Dyak\GE13392 Y   Drosophila ananassae   Dana\GF12967 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA24867 Y   Drosophila persimilis   Dper\GL17673 Y   Drosophila willistoni   Dwil\GK21396 Y   Drosophila virilis   Dvir\GJ21475 Y   Drosophila mojavensis   Dmoj\GI18397 Y   Drosophila grimshawi   Dgri\GH24950 Y
Orthologs in non-Drosophila Dipterans (EOG6PG687)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008260   Anopheles gambiae Malaria mosquito  Agam\AGAP011180   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ019459
Orthologs in non-Dipteran Insects (EOG68SFP8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB44753 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001169 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21842 Y Atta cephalotes Leafcutter ant  Acep\ACEP27717 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19841 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21379 Y Linepithema humile Argentine ant  Lhum\LH21144 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB25928 Y Solenopsis invicta Red fire ant  Sinv\SINV12871 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000147 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI068617 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005232 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI002112 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI002242 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI003611 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009060 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005730 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000708 Y Bombyx mori Silkmoth  Bmor\BGIBMGA008774 Y Pediculus humanus Human body louse  Phum\PHUM157200 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15663 Y
Orthologs in non-Insect Arthropods (EOG669P90)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_48413 Y Ixodes scapularis Deer tick  Isca\ISCW019624 Y
Orthologs in non-Arthropod Metazoa (EOG6PP98Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\jmjd-2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012300gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020051gn Y Danio rerio Zebrafish  Drer\si:ch211-262l3.1 Y Danio rerio Zebrafish  Drer\ENSDARG00000018782 Y Danio rerio Zebrafish  Drer\kdm4b Y Danio rerio Zebrafish  Drer\zgc:153957 Y Xenopus tropicalis Western clawed frog  Xtro\kdm4a Y Xenopus tropicalis Western clawed frog  Xtro\kdm4c Y Xenopus tropicalis Western clawed frog  Xtro\kdm4b Y Gallus gallus Domestic chicken  Ggal\KDM4A Y Gallus gallus Domestic chicken  Ggal\KDM4C Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000004091 Y Mus musculus House mouse  Mmus\Kdm4a Y Mus musculus House mouse  Mmus\Kdm4d Y Mus musculus House mouse  Mmus\Kdm4b Y Mus musculus House mouse  Mmus\Kdm4c Y Rattus norvegicus Norway rat  Rnor\Kdm4d Y Rattus norvegicus Norway rat  Rnor\Kdm4c Y Rattus norvegicus Norway rat  Rnor\Kdm4a Y Homo sapiens Human  Hsap\KDM4DL Y Homo sapiens Human  Hsap\KDM4C Y Homo sapiens Human  Hsap\KDM4A Y Homo sapiens Human  Hsap\KDM4D Y Homo sapiens Human  Hsap\KDM4B Y
Human Orthologs (5)
Gene OMIM HGNC Hsap\KDM4DL     Hsap\KDM4C     Hsap\KDM4A     Hsap\KDM4D     Hsap\KDM4B
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM20306 Drosophila erecta Dere\GG22520 Drosophila yakuba Dyak\GE13392 Drosophila ananassae Dana\GF12967 Drosophila pseudoobscura pseudoobscura Dpse\GA24867 Drosophila persimilis Dper\GL17673 Drosophila willistoni Dwil\GK21396 Drosophila virilis Dvir\GJ21475 Drosophila mojavensis Dmoj\GI18397 Drosophila grimshawi Dgri\GH24950
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	20208 y1 w67c23; P{EPgy2}Kdm4BEY10737 35676 y1 sc* v1; P{TRiP.GLV21041}attP2 14963 y1 w67c23; P{SUPor-P}Kdm4BKG08629 11336 cn1 P{PZ}Aats-val03531 Kdm4B03531/CyO; ry506
Harvard	- PBac{PB}Kdm4Bc03262
Kyoto	103764 w*; P{GawB}Kdm4BNP0792 / CyO 104142 w*; P{GawB}Kdm4BNP2264 / SM1 112848 w*; P{GawB}Kdm4BNP2264 / CyO
VDRC	v46444 w1118; P{GD16017}v46444
Genomic Clones ( 2 )
	BACR05M17 BACR48I10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 126 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT26080 HL08087 LD07176 LD16673 LD47433
Other clones	DPiM_HL08087 DPiM_LD47433 IP01972 IP18301 MIP04757
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02210 AT07601 AT25578 AT25592 GH25520 LD05485 LD15430 LD18990 LD42211 LD45753 LD47446 LP12864 RE28517 RE63617
Other clones	11367 31884 37290 45812 60559 74095 79833 97999 101493 119341 124183 161481 173785 191251 214225.31 214283.39 275442 bs54b06 CK01.8D.F12 CK01.21A.E8 CK01.118C.F6 CK01.122A.B2 Dmel_dig_002877_0691_2556 Dmel_dig_005637_0589_2629 Dmel_dig_007305_0608_2519 Dmel_dig_008802_0616_3599 Dmel_dig_019325_0630_3324 EC30337 EC36979 EK019452 EK089855 EK093237 EK111951 EK142510 EK155638 EK162259 EK191249 EK212515 EK220745 EK228343 EK238823 EK246615 EK265310 EK302945 EP12537 FGM226G05 IP01969 IP01970 IP04701 IP18001 IP18101 IP18201 LD09818 LD22079 RE23326 RP003009742 RP003058248 RP003064375 RP003068344 RP003078760 RP003137244 RP003172850 RP003189170 RP003192327 RP003217122 RP003251813 RP003268709 RP003271826 RP003276616 RP003278880 RP003281114 RP003292746 RP003314806 RP003381210 RP003389554 RP003390626 RP003396655 RP003439829 RP003454917 RP003489588 RP003530730 RP003597770 RP003667961 RP003669648 RP003680677 RP004066438 RP004083609 RP004122344 RP004162202 RP004201269 RP004217527 RP004233666 RP004264043 RP004299507 RP004305665 RP004342067 RP004399343 RP004414005 RP004447060 RP004496996 RP004498922 SD10649
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0053182 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318918
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Kdm4B CG33182 (Lin et al., 2008)
Source for database merge of
Additional comments	One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by Kdm4B and CG17724. (FlyBase Genome Annotators, 2012) Annotation CG4037 split into CG33182, CG32904 (seq) and CG17724 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_176164 NM_001169666 NM_001169667 NM_001169668 NM_001274013 RefSeq (Proteins) • NP_788344 NP_001163137 NP_001163138 NP_001163139 NP_001260942 DDBJ / EMBL / GenBank • AAF58413 ACZ94410 ACZ94411 ACZ94412 AGB93475 BI231706 CL844353 CZ468544 Entrez Gene - A searchable database of RefSeq genes. • 318918 UniProtKB/Swiss-Prot • Q9V6L0 UniProtKB/TrEMBL • E1JH52
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • JmjC domain (IPR003347) Transcription factor jumonji, JmjN (IPR003349)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0053182 DRSC - Results from RNAi screens. • FBgn0053182 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053182 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33182-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0053182 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318918 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 318918 modMine - Data generated by the modENCODE project. • FBgn0053182
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	CG4037   CG33182 (Lloret-Llinares et al., 2008, Curtis et al., 2011, Lin et al., 2008, Stofanko et al., 2008, Klose et al., 2006, UniProtKB Project Members, 2006.5.16, Lorbeck et al., 2010, Schneiderman et al., 2010, Keleman et al., 2009.8.5, Ni et al., 2011.7.19, Japanese National Institute of Genetics, 2012.5.21) dJMJD2(2) (Lloret-Llinares et al., 2008) dKDM4B (Lin et al., 2008) dKdm4B (Palomera-Sanchez et al., 2010) Kdm4B (Gan et al., 2010, FlyBase Genome Annotators, 2012) KDM4B (Kwon et al., 2010)
Name Synonym	CG33182   Histone demethylase 4B
Secondary FlyBase IDs
	FBgn0033804
References ( 25 )
Generate a list of	All references relating to this gene ( 25 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 2 ) Review  ( 1 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 4 ) Protein sequence record  ( 1 ) Stock list  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Curtis et al., 2011, Dev. Biol. 350(2): 534--547 Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development. [FBrf0212876] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...