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Gene Dmel\dp

General Information
Symbol	Dmel\dp	Species	D. melanogaster
Name	dumpy	Annotation symbol	CG33196
Feature type	protein_coding_gene	FlyBase ID	FBgn0053196
Gene Model Status	Current	Stock availability	393 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map	2-13.0
Cytogenetic map	24F4-25A1	Sequence location	2L:4,477,462..4,614,300 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene dumpy is referred to in FlyBase by the symbol Dmel\dp (CG33196, FBgn0053196). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: extracellular matrix structural constituent. There is experimental evidence that it is involved in the biological process: apposition of dorsal and ventral imaginal disc-derived wing surfaces; chitin-based cuticle attachment to epithelium; lateral inhibition; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 325 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; organ system; adult segment; thoracic segment; adult; late extended germ band embryo; non-connected developing system; tracheal branch primordium; eo support cell; adult trachea. It has 16 annotated transcripts and 16 annotated polypeptides. Protein features are: Complement Clr-like EGF domain; Cysteine-rich repeat; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Endonuclease III-like, iron-sulphur cluster loop motif; Epidermal growth factor-like domain; Follistatin-like, N-terminal; Green fluorescent protein-like; Growth factor, receptor; Proteinase inhibitor I7, squash; Zona pellucida domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, larval/adult hindgut, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1634075_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of dp. Gene sequence location is 2L:4477462..4595054.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	dp: dumpy dpo: dumpy-oblique From Bridges and Brehme, 1944, Carnegie Inst. Washington Publ. No. 552: 65. dpov: dumpy-oblique vortex Edith Wallace, unpublished. dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and reducing wings to approximately half normal length in extreme genotypes, where the truncation is more nearly perpendicular to the long axis of wing. Margins remain intact; angle between veins L2 and L5 increased, and intercrossvein distance decreased. Phenotype resembles rudimentary. Thoracic phenotype comprises five types of hypodermal irregularities: first vortices, second vortices, commas, pre-episternal pits, and posterior invagination; all five have the form of pits, eruptions, or raised pits of the cuticle (Metcalfe, 1970, Genetics 65: 627-54). First vortices are hypodermal pits or eruptions located posterolaterally on the scutum; they disrupt the acrostichal rows, resulting in surrounding whorls of microchaete. Second vortices are located anterolaterally on the scutum and resemble first vortices morphologically. Commas are comma-shaped depressions at the anterior margin of the scutum. The pre-episternal pit is in the pre-episternal plate immediately anterior to the sternopleural chaetae, which sometimes exhibit disturbed orientation (Metcalf, 1969, DIS 44: 91). The posterior invagination occurs between the laterotergite plate and the metanotum (Metcalf, 1969); different alleles exhibit different combinations of these traits. Musculature attached to disturbed regions of the cuticle often degenerates (Metcalfe, 1970). Some alleles show reduced body size and small weak legs (dph, dpobw females, dpolv/dpov). Phenotypic expression enhanced by increased temperature during development; wing and thorax effects show dominance when heterozygotes exposed to increased temperatures at 12-16 and 8-10 hr of pupal life, respectively (Blanc and Child, 1940, Physiol. Zool. 13: 65-72). Normal larvae fed 6-azauracil produce adults with oblique phenocopies; 6-azauracil feeding suppresses dp (Rizki and Rizki, 1965, Science 150: 222-23), su(r) enhances the oblique phenotype (Stroman, 1974, Hereditas 78: 157-68). The four genotypes studied [dpo2, dpovN, dpv2, and dpv; e(dpv)] show increased orotate phosphoribosyl transferase activity during third larval instar and enhanced incorportion of labeled glucose into chitin (Blass and Hunt, 1980, Mol. Gen. Genet. 178: 437-42). Many alleles are lethal when homozygous; they are identified by l in the allelic designation. Lethal stages vary among alleles, e.g., dpolv is embryonic lethal; dplv1, and dplvI die at the egg-larval boundary; dplm homozygotes die primarily at larval ecdysis between the first and second larval instar with some death at hatching and at ecdysis of second-instar larvae; dpobm homozygotes die mostly at hatching but a few die during first and second larval instars (Metcalfe, 1971, Genet. Res. 17: 173-83). In Me/+ heterozygotes, many dp alleles show a dominant oblique effect when heterozygous for dp+ and dp; dpv is an exception (Carlson, 1959). dpv homozygotes normal; show thoracic phenotype only if third chromosomes homozygous for e(dpv).
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 24F4-25A1   Limits computationally determined from genome sequence between P{lacW}Tps1k08903&P{EP}morgueEP1184 and P{lacW}l(2)k10004k10004&P{EP}CG3036EP963
Experimentally Determined Cytological Location
Cytogenetic map Notes References 25A1-25A2     (Serano, 1999.12.13) 24F-25A   (determined by in situ hybridisation)   (MacIntyre, 1991)   Maps in or near 25A3--25A4.   (Roberts and Broderick, 1982)
Experimentally Determined Recombination Data
Location	2-13.0 (Carlson, 1955, Goldschmidt, 1944, Reuter and Szidonya, 1983, Edmondson, 1952, Arvelighetsinstitutten, University) 2-13 (Carlson, 1956)
Left of (cM)
Right of (cM)	Fs(2)M (Szabad et al., 1989) Pgk (Voelker et al., 1979)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\dp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Gene model reviewed during 5.51 Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters. Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) dp-RAA FBtr0332355  NM_001273113   59206   19560 dp-RI FBtr0305141  NM_001258946   47440   15638 dp-RJ FBtr0305142  NM_001258947   48068   15105 dp-RM FBtr0305145  NM_001258950   26263   8579 dp-RO FBtr0332343  NM_001273101   68745   22743 dp-RP FBtr0332344  NM_001273102   62656   20710 dp-RQ FBtr0332345  NM_001273103   71382   22949 dp-RR FBtr0332346  NM_001273104   69016   22830 dp-RS FBtr0332347  NM_001273105   56449   18641 dp-RT FBtr0332348  NM_001273106   69435   22300 dp-RU FBtr0332349  NM_001273107   67506   21657 dp-RV FBtr0332350  NM_001273108   63747   20404 dp-RW FBtr0332351  NM_001273109   56567   18014 dp-RX FBtr0332352  NM_001273110   47000   14825 dp-RY FBtr0332353  NM_001273111   54801   18095 dp-RZ FBtr0332354  NM_001273112   50529   15998
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein dp-PAA   FBpp0304632   2082.0   19560   4.77     NP_001260042   AGB92578 dp-PI   FBpp0293671   1662.7   15638   4.68     NP_001245875   AFH03551 dp-PJ   FBpp0293672   1606.4   15105   4.65     NP_001245876   AFH03552 dp-PM   FBpp0293675   915.9   8579   5.21     NP_001245879   AFH03555 dp-PO   FBpp0304620   2421.1   22743   4.89     NP_001260030   AGB92566 dp-PP   FBpp0304621   2204.3   20710   4.89     NP_001260031   AGB92567 dp-PQ   FBpp0304622   2443.4   22949   4.91     NP_001260032   AGB92568 dp-PR   FBpp0304623   2430.9   22830   4.91     NP_001260033   AGB92569 dp-PS   FBpp0304624   1986.2   18641   5.40     NP_001260034   AGB92570 dp-PT   FBpp0304625   2373.9   22300   4.88     NP_001260035   AGB92571 dp-PU   FBpp0304626   2306.1   21657   4.87     NP_001260036   AGB92572 dp-PV   FBpp0304627   2176.1   20404   4.97     NP_001260037   AGB92573 dp-PW   FBpp0304628   1915.8   18014   4.70     NP_001260038   AGB92574 dp-PX   FBpp0304629   1576.3   14825   4.63     NP_001260039   AGB92575 dp-PY   FBpp0304630   1927.0   18095   5.35     NP_001260040   AGB92576 dp-PZ   FBpp0304631   1702.8   15998   5.16     NP_001260041   AGB92577
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Green fluorescent protein-like (IPR023413) Complement Clr-like EGF domain (IPR026823) Epidermal growth factor-like domain (IPR000742) EGF-like calcium-binding, conserved site (IPR018097) Endonuclease III-like, iron-sulphur cluster loop motif (IPR003651) EGF-type aspartate/asparagine hydroxylation site (IPR000152) Cysteine-rich repeat (IPR006150) EGF-like calcium-binding (IPR001881) Insulin-like growth factor binding protein, N-terminal (IPR009030) Zona pellucida domain (IPR001507) EGF-like, conserved site (IPR013032) Follistatin-like, N-terminal (IPR003645) Proteinase inhibitor I7, squash (IPR000737) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1OIG
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AF214523 AAF24502   AE014134 AFH03551   AE014134 AFH03552   AE014134 AFH03555   AE014134 AGB92566   AE014134 AGB92567   AE014134 AGB92568   AE014134 AGB92569   AE014134 AGB92570   AE014134 AGB92571   AE014134 AGB92572   AE014134 AGB92573   AE014134 AGB92574   AE014134 AGB92575   AE014134 AGB92576   AE014134 AGB92577   AE014134 AGB92578   AI107368   AI258776   AI295308   AI517722   AI531228   AI534569   AI541731   AY122242 AAM52754   BG633019   BG636147   BG639811   BI372272   BI588451   BI611411   BI623460   BI631010   BT100056   CK657581   CK659442   CO152794   CO152865   CO152950   CO152960   CO153144   CO153366   CO153583   CO153587   CO154038   CO154040   CO154055   CO154097   CO154589   CO154604   CO154719   CO154996   CO155164   CO155425   CO155702   CO155808   CO156315   CO156379   CO156491   CO156643   CO156897   CO178507   CO180125   CO184873   CO187191   CO268543   CO269997   CO286110   CO291200   CO295232   CO305662   CO307092   CO311218   CO313274   CO314465   CO315015   CO316287   CO317112   CO317468   CO317547   CO318271   CO319175   CO319631   CO324546   CO325337   CO326252   CO327887   CO329143   CO329353   CO335641   CO337050   CO337146   CO337394   CO337407   CO337427   CO337485   CO337604   CO337658   CO338148   CO338167   CO338223   CO338224   CO338320   CO338474   CO338602   CO340055   CO342230   CZ467077   CZ470643   EC053302   EC065175   EC065986   EC066801   EC078485   EC089508   EC195027   EC199880   EC207247   EC208663   EC227408   EC247536   EC249796   EC263645   EL870560   EL873516   EY198902   FE527601   GH291391   GH291398   GH291435   GH291445   GH291457   GO271019   GO271075   GO271150
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MQX8 Q8IQ18 Q9U3W7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) tracheal primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic esophagus   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic rectum   (Fisher et al., 2012) embryonic small intestine   (Fisher et al., 2012) embryonic/larval dorsal branch   (Fisher et al., 2012) embryonic/larval dorsal trunk   (Fisher et al., 2012) embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval pericardial cell   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, larval/adult hindgut, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea    1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea  (1048.075) Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea  1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea    1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea    1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea  (1048.075) Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea  1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    12.35 Larval Midgut    11.2 Larval Hindgut    178.1 Larval Malpighian Tubules    10.7 Larval Fat Body    16.2 Larval Salivary Gland    18.6 Larval Trachea    1048.075 Larval Carcass    116.825 Adult Head    31.5 Adult Eye    427.325 Adult Brain    4 Adult Thoracic-Abdominal Ganglion    9.7 Adult Crop    170.5 Adult Midgut    16.4 Adult Hindgut    143.9 Adult Malpighian Tubules    8.4 Adult Fat Body    17.2 Adult Salivary Gland    81.6 Adult Heart    19.3 Adult VirginFemale Spermatheca    56.3 Adult InseminatedFemale Spermatheca    98.8 Adult Ovary    5.9 Adult Testis    8.3 Adult Male Accessory Gland    14.8 Adult Carcass    55.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    31.5   NA  Eye    427.325   NA  Brain    4   no informative data  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    9.7   NA  Crop    170.5   no informative data  Midgut    no informative data   178.1  Hindgut    143.9   no informative data  Malpighian Tubules    8.4   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    no informative data   1048.075  Trachea    NA   NA  VirginFemale Spermatheca    56.3   NA  InseminatedFemale Spermatheca    98.8   NA  Ovary    5.9   NA  Testis    8.3   NA  Male Accessory Gland    no informative data   116.825  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    9 head, virgin 4-day female    4 head, virgin 20-day female    3 head, mated 1-day female    6 head, mated 4-day female    3 head, mated 20-day female    3 head, mated 1-day male    10 head, mated 4-day male    6 head, mated 20-day male    5 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    1 carcass, larvae L3 wandering    12 carcass, 1-day adult    4 carcass, 4-day adult    2 carcass, 20-day adult    2 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    2 embryo 06-08hr    5 embryo 08-10hr    5 embryo 10-12hr    1 embryo 12-14hr    4 embryo 14-16hr    10 embryo 16-18hr    12 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    6 larva L1    8 larva L2    10 larva L3 12hr old    17 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    13 pupae 2d postWPP    9 pupae 3d postWPP    9 pupae 4d postWPP    8 adult male 01day    10 adult male 05day    7 adult male 30day    9 adult female 01day    8 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    3 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    1 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    1 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_29 mE1_20_mRNA_expression_cluster_14
External Data & Images
Linkouts	BDGP expression data • SD02173 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053196 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33196-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for dp Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal dplv1 dpol4 dpol dpolb20 dpolb27 dpolb42 dpolCS19 dpolCS41 dpolCS50 dpolCS80 dpolCS109 dpolDG9 lethal (with dp2f1-olv) dplv1 dpolvR lethal (with dp2f2-lv) dplv1 dpolvR lethal (with dp2f3-olv) dplv1 dpolvR lethal (with dplv1) dp2f1-olv dp2f2-lv dp2f3-olv lethal (with dpolvR) dp2f1-olv dp2f2-lv dp2f3-olv lethal | recessive dpD dpdvM516 dpl20 dplb1 dplDG82 dplDG83 dplDG85 dplDG91 dplh40 dplh41 dplM57f dplM dplm dplsz31 dplsz46 dplv1 dplv2 dplv44 dplv51e dplvb21 dplvCS24 dplvCS35 dplvCS36 dplvCS38 dplvCS42 dplvCS43 dplvCS51 dplvCS58 dplvCS67 dplvCS78 dplvCS81 dplvCS105 dplvDG1 dplvDG3 dplvDG5 dplvDG7 dplvDG10 dplvDG12 dplvDG13 dplvDG14 dplvDG16 dplvDG23 dplvDG24I dplvDG38 dplvDG49 dplvDG50 dplvDG51 dplvDG57 dplvDG58 dplvDG65 dplvDG66 dplvDG67 dplvDG72 dplvDG78 dplvDG81 dplvem1 dplvem2 dplvem4 dplvh37 dplvI dplvx1 dplvx2 dplvx3 dplvx4 dplvx5 dplvx18 dpol4 dpolAS dpolb20 dpolb27 dpolb42 dpolCS19 dpolCS41 dpolCS50 dpolCS80 dpolCS109 dpolDG9 dpoldx3 dpolem1 dpolem8 dpolem9 dpolh6 dpolh8 dpolh9 dpolh10 dpolh12 dpolh20 dpolh21 dpolM dpolsz24 dpolv2 dpolv6m dpolv54d dpolv55b dpolv55c dpolv57g dpolv101 dpolv dpolva22 dpolvb12 dpolvbm dpolvCG112 dpolvCS3 dpolvCS8 dpolvCS24 dpolvCS28 dpolvCS39 dpolvCS69 dpolvCS93 dpolvCS95 dpolvCS100 dpolvCS103 dpolvCS108 dpolvCS112 dpolvD dpolvDG10 dpolvDG20 dpolvDG27 dpolvDG32 dpolvDG34 dpolvDG44 dpolvDG45 dpolvDG46 dpolvDG59 dpolvDG61 dpolvDG62 dpolvDG63 dpolvDG72 dpolvDG75 dpolvem4 dpolvem5 dpolvem6 dpolvem7 dpolvem8 dpolvem9 dpolvem10 dpolvem11 dpolvh2 dpolvh3 dpolvh4 dpolvh5 dpolvh7 dpolvh11 dpolvh14 dpolvh17 dpolvh18 dpolvh22 dpolvh26 dpolvh27 dpolvh29 dpolvH dpolvHC3 dpolvHC39 dpolvHC59 dpolvHC69 dpolvHC234 dpolvM dpolvP dpolvR dpolvS dpolvSn dpolvsz28 dpolvW dpolvx1 dpolvx2 dpolvx4 dpolvx5 dpolXAS1 dpunspecified partially lethal - majority die, with Scer\GAL4pnr-MD237 dpGD10346 partially lethal - majority die | cold sensitive dpcm2 viable dpov51f viable, with Scer\GAL4pnr-MD237 dpGD4443 dpGD10345 dpGD10420 dpGD10421 dpGD10422 dpGD10423 viable | reduced dpcm2 Sterility Allele fertile dpov51f Other Phenotypes Allele enhancer of variegation | dominant (with dpolv-12), with Psf2SH0805 dpw18 enhancer of variegation | dominant (with dpw18), with Psf2SH0805 dpolv-12 immune response defective | adult stage dpov1 planar polarity defective, with Scer\GAL4pnr-MD237 dpGD10345 dpGD10346 suppressor of variegation | dominant dpolh8 dpolh9 dpolh10 dpolh12 dpolh20 dpolh21 dpolM suppressor of variegation | dominant (with dpolv-12), with Su(var)2055 dpw18 suppressor of variegation | dominant (with dpw18), with Su(var)2055 dpolv-12 visible dpcm dply dpo dpov1 dpov52b dpTC-1 dpTC-2 dpv2 dpv visible, with Scer\GAL4pnr-MD237 dpGD10345 dpGD10422 visible (with dp2f1-olv) dpov1 visible (with dp2f2-lv) dpov1 visible (with dp2f3-olv) dpov1 visible (with dpov1) dp2f1-olv dp2f2-lv dp2f3-olv visible | cold sensitive dpcm2 visible | dominant dpD3 dpD4 dpD dpDA dpolvR visible | recessive dpdvM516 dplv1 dplv2 dplv44 dplv51e dplvb21 dplvCS24 dplvCS35 dplvCS36 dplvCS38 dplvCS42 dplvCS43 dplvCS51 dplvCS58 dplvCS67 dplvCS78 dplvCS81 dplvCS105 dplvDG1 dplvDG3 dplvDG5 dplvDG7 dplvDG10 dplvDG12 dplvDG13 dplvDG14 dplvDG16 dplvDG23 dplvDG24I dplvDG38 dplvDG49 dplvDG50 dplvDG51 dplvDG57 dplvDG58 dplvDG65 dplvDG66 dplvDG67 dplvDG72 dplvDG78 dplvDG81 dplvem1 dplvem2 dplvem4 dplvh37 dplvI dplvx1 dplvx2 dplvx3 dplvx4 dplvx5 dplvx18 dpo2 dpo2v2 dpo3 dpo33 dpo51e dpo dpoA2 dpoA4 dpobm dpobw dpodef dpoDG6 dpoDG33 dpoDG41 dpoDG53I dpoDG56 dpoem2 dpoem9 dpoem10 dpoem11 dpoh13 dpol4 dpol dpolAS dpolb20 dpolb27 dpolb42 dpolCS19 dpolCS41 dpolCS50 dpolCS80 dpolCS109 dpolDG9 dpoldx3 dpolem1 dpolem8 dpolem9 dpolh6 dpolh8 dpolh9 dpolh10 dpolh12 dpolh20 dpolh21 dpolM dpolsz24 dpolv2 dpolv6m dpolv54d dpolv55b dpolv55c dpolv57g dpolv101 dpolv dpolva22 dpolvb12 dpolvbm dpolvCG112 dpolvCS3 dpolvCS8 dpolvCS24 dpolvCS28 dpolvCS39 dpolvCS69 dpolvCS93 dpolvCS95 dpolvCS100 dpolvCS103 dpolvCS108 dpolvCS112 dpolvD dpolvDG10 dpolvDG20 dpolvDG27 dpolvDG32 dpolvDG34 dpolvDG44 dpolvDG45 dpolvDG46 dpolvDG59 dpolvDG61 dpolvDG62 dpolvDG63 dpolvDG72 dpolvDG75 dpolvem4 dpolvem5 dpolvem6 dpolvem7 dpolvem8 dpolvem9 dpolvem10 dpolvem11 dpolvh2 dpolvh3 dpolvh4 dpolvh5 dpolvh7 dpolvh11 dpolvh14 dpolvh17 dpolvh18 dpolvh22 dpolvh26 dpolvh27 dpolvh29 dpolvH dpolvHC3 dpolvHC39 dpolvHC59 dpolvHC69 dpolvHC234 dpolvM dpolvP dpolvS dpolvSn dpolvsz28 dpolvW dpolvx1 dpolvx2 dpolvx4 dpolvx5 dpolXAS1 dposz66 dpou dpov1 dpov7 dpov51f dpov51h dpov52b dpovDG2 dpovDG27 dpovDG30 dpovDG35 dpovDG37 dpovDG61 dpovdr dpovh dpovN dpT56e dpunspecified dpv2 dpv7 dpvem3 dpvM dpvsz4 dpvW visible | semidominant dplM visible | somatic clone dplv1 dpunspecified wild-type dpv Phenotype manifest in Allele adult dpolv adult abdomen dpobw dpolAS dpovh adult thorax dplvI dpobw dpolAS dpolM dpolv dpov1 dpovh adult thorax (with dp2f1-olv) dpov1 adult thorax (with dp2f2-lv) dpov1 adult thorax (with dp2f3-olv) dpov1 adult thorax (with dpov1) dp2f1-olv dp2f2-lv dp2f3-olv dpv2 adult thorax (with dpv2) dpov1 adult thorax & adult epidermis dpD dpT56e dpcm dpcm2 dpdvM516 dplv1 dplv2 dplv44 dplv51e dplvCS105 dplvCS24 dplvCS35 dplvCS36 dplvCS38 dplvCS42 dplvCS43 dplvCS51 dplvCS58 dplvCS67 dplvCS78 dplvCS81 dplvDG1 dplvDG10 dplvDG12 dplvDG13 dplvDG14 dplvDG16 dplvDG23 dplvDG24I dplvDG3 dplvDG38 dplvDG49 dplvDG5 dplvDG50 dplvDG51 dplvDG57 dplvDG58 dplvDG65 dplvDG66 dplvDG67 dplvDG7 dplvDG72 dplvDG78 dplvDG81 dplvI dplvb21 dplvem1 dplvem2 dplvem4 dplvh37 dplvx1 dplvx18 dplvx2 dplvx3 dplvx4 dplvx5 dpolXAS1 dpoldx3 dpolv dpolv101 dpolv2 dpolv54d dpolv55b dpolv55c dpolv57g dpolv6m dpolvCG112 dpolvCS100 dpolvCS103 dpolvCS108 dpolvCS112 dpolvCS24 dpolvCS28 dpolvCS3 dpolvCS39 dpolvCS69 dpolvCS8 dpolvCS93 dpolvCS95 dpolvD dpolvDG10 dpolvDG20 dpolvDG27 dpolvDG32 dpolvDG34 dpolvDG44 dpolvDG45 dpolvDG46 dpolvDG59 dpolvDG61 dpolvDG62 dpolvDG63 dpolvDG72 dpolvDG75 dpolvH dpolvHC234 dpolvHC3 dpolvHC39 dpolvHC59 dpolvHC69 dpolvM dpolvP dpolvR dpolvS dpolvSn dpolvW dpolva22 dpolvb12 dpolvbm dpolvem10 dpolvem11 dpolvem4 dpolvem5 dpolvem6 dpolvem7 dpolvem8 dpolvem9 dpolvh11 dpolvh14 dpolvh17 dpolvh18 dpolvh2 dpolvh22 dpolvh26 dpolvh27 dpolvh29 dpolvh3 dpolvh4 dpolvh5 dpolvh7 dpolvsz28 dpolvx1 dpolvx2 dpolvx4 dpolvx5 dpov1 dpov51f dpov51h dpov52b dpov7 dpovDG2 dpovDG27 dpovDG30 dpovDG35 dpovDG37 dpovDG61 dpovN dpovdr dpovh dpv2 dpv7 dpvM dpvW dpvem3 dpvsz4 cerebral branch dpolvR chaeta | supernumerary, with Scer\GAL4pnr-MD237 dpGD10345 dorsal branch dpolvR dorsocentral bristle dpov1 endocuticle dplv1 lateral trunk anterior branch dpolvR lateral trunk posterior branch dpolvR leg dpTC4 dpobw dpolAS dpolv dpovh macrochaeta dpunspecified mesothoracic tergum dpov1 dpunspecified mesothoracic tergum, with Scer\GAL4pnr-MD237 dpGD10345 dpGD10422 muscle attachment site dpunspecified pharyngeal branch dpolvR presumptive embryonic/larval tracheal system dpOVLR sternopleural bristle dplv1 dplv2 thorax dpD dpTC-2 dply dpo dpv dpv2 thorax & microchaeta dpTC-2 trichogen cell, with Scer\GAL4pnr-MD237 dpGD10422 ventral cephalic branch dpolvR visceral branch | embryonic stage dpolvR wing dpD dpDA dpT56e dpTC-1 dpTC-2 dpcm2 dpdvM516 dplM dplv2 dplv51e dplvI dply dpo dpo2 dpo2v2 dpo3 dpo33 dpo51e dpoA2 dpoA4 dpoDG33 dpoDG41 dpoDG53I dpoDG56 dpoDG6 dpobm dpobw dpodef dpoem10 dpoem11 dpoem2 dpoem9 dpoh13 dpol dpol4 dpolAS dpolCS109 dpolCS19 dpolCS41 dpolCS50 dpolCS80 dpolDG9 dpolM dpolXAS1 dpolb20 dpolb27 dpolb42 dpoldx3 dpolem1 dpolem8 dpolem9 dpolh10 dpolh12 dpolh20 dpolh21 dpolh6 dpolh8 dpolh9 dpolsz24 dpolv dpolv101 dpolv2 dpolv54d dpolv55b dpolv55c dpolv57g dpolv6m dpolvCG112 dpolvCS100 dpolvCS103 dpolvCS108 dpolvCS112 dpolvCS24 dpolvCS28 dpolvCS3 dpolvCS39 dpolvCS69 dpolvCS8 dpolvCS93 dpolvCS95 dpolvD dpolvDG10 dpolvDG20 dpolvDG27 dpolvDG32 dpolvDG34 dpolvDG44 dpolvDG45 dpolvDG46 dpolvDG59 dpolvDG61 dpolvDG62 dpolvDG63 dpolvDG72 dpolvDG75 dpolvH dpolvHC234 dpolvHC3 dpolvHC39 dpolvHC59 dpolvHC69 dpolvM dpolvP dpolvR dpolvS dpolvSn dpolvW dpolva22 dpolvb12 dpolvbm dpolvem10 dpolvem11 dpolvem4 dpolvem5 dpolvem6 dpolvem7 dpolvem8 dpolvem9 dpolvh11 dpolvh14 dpolvh17 dpolvh18 dpolvh2 dpolvh22 dpolvh26 dpolvh27 dpolvh29 dpolvh3 dpolvh4 dpolvh5 dpolvh7 dpolvsz28 dpolvx1 dpolvx2 dpolvx4 dpolvx5 dposz66 dpou dpov1 dpov51f dpov51h dpov52b dpov7 dpovDG2 dpovDG27 dpovDG30 dpovDG35 dpovDG37 dpovDG61 dpovN dpovdr dpovh dpunspecified wing (with dp2f1-olv) dpov1 wing (with dp2f3-olv) dpov1 wing (with dpo2) dpov1 wing (with dpov1) dp2f1-olv dp2f3-olv dpo2 wing | somatic clone dpunspecified wing blade | somatic clone dplv1 wing vein dpunspecified
Classical Alleles ( 304 )
For All Classical Alleles Show
Allele of dp Class Mutagen Stocks Known lesion dpov1 spontaneous 166 Yes dplv1 spontaneous 158 -- dpo2 spontaneous 23 Yes dplv2 spontaneous 5 -- dplvI spontaneous 3 -- dpovN X ray 3 -- dpv2 spontaneous 3 Yes dpv spontaneous 3 Yes dpD X ray 2 -- dpDA neutrons 2 -- dpo3 2 -- dpolvh27 X ray 2 -- dpolvR X ray 2 -- dpBG01429 P-element activity 1 Yes dpc00648 1 -- dplDG82 nitrosomethyl urea 1 Yes dplDG83 nitrosomethyl urea 1 -- dplvDG12 1 -- dplvDG7 1 -- dpMB00453 1 -- dpoA4 1 -- dpolM U.V. 1 -- dpolvHC3 1 -- dpovDG2 1 Yes dpovh spontaneous 1 -- dp1 0 -- dp2 0 -- dp2f1-olv ethyl methanesulfonate 0 -- dp2f2-lv ethyl methanesulfonate 0 -- dp2f3-olv ethyl methanesulfonate 0 -- dp49 X ray 0 -- dp53 spontaneous 0 -- dp58 spontaneous 0 -- dp61d X ray 0 -- dpc01324 piggyBac transposase 0 -- dpc06378 piggyBac transposase 0 -- dpCA2 X ray 0 -- dpCA5 X ray 0 -- dpCA6 X ray 0 -- dpCA9 0 -- dpcm2 spontaneous 0 -- dpcm spontaneous 0 -- dpCPTI001769 piggyBac transposase 0 Yes dpD1311A spontaneous 0 Yes dpD3 0 -- dpD4 0 -- dpdvM516 0 -- dpG3030B spontaneous 0 Yes dpG8202B spontaneous 0 Yes dpG spontaneous 0 -- dpH1230B spontaneous 0 Yes dph24 0 -- dpJazz-12 0 -- dpl20 0 -- dpL2311B spontaneous 0 Yes dplb1 ethyl methanesulfonate 0 -- dplDG85 0 -- dplDG91 0 -- dplh40 X ray 0 -- dplh41 X ray 0 -- dplM57f 0 -- dplM 0 -- dplm U.V. 0 -- dplMi spontaneous 0 -- dplsz31 ethyl methanesulfonate 0 -- dplsz46 ethyl methanesulfonate 0 -- dplv12 gamma ray 0 Yes dplv16 gamma ray 0 Yes dplv23b ethyl methanesulfonate 0 Yes dplv44 X ray 0 -- dplv51e U.V. 0 -- dplv65f ethyl methanesulfonate 0 Yes dplv7a ethyl methanesulfonate 0 Yes dplvb21 ethyl methanesulfonate 0 -- dplvCS105 ICR 170 0 -- dplvCS24 ICR 170 0 -- dplvCS35 ICR 170 0 -- dplvCS36 ICR 170 0 -- dplvCS38 ICR 170 0 -- dplvCS42 0 -- dplvCS43 ICR 170 0 -- dplvCS51 ICR 170 0 -- dplvCS58 ICR 170 0 -- dplvCS67 ICR 170 0 -- dplvCS78 ICR 170 0 -- dplvCS81 ICR 170 0 -- dplvD1191A spontaneous 0 Yes dplvDG10 0 -- dplvDG13 0 -- dplvDG14 0 -- dplvDG16 0 -- dplvDG1 0 -- dplvDG23 0 -- dplvDG24I 0 -- dplvDG38 0 -- dplvDG39 0 -- dplvDG3 nitrosomethyl urea 0 -- dplvDG49 0 -- dplvDG50 0 -- dplvDG51 0 -- dplvDG57 0 -- dplvDG58 0 -- dplvDG5 nitrosomethyl urea 0 -- dplvDG65 nitrosomethyl urea 0 -- dplvDG66 0 -- dplvDG67 0 -- dplvDG72 0 -- dplvDG78 nitrosomethyl urea 0 -- dplvDG81 0 -- dplvem1 ethyl methanesulfonate 0 -- dplvem2 ethyl methanesulfonate 0 -- dplvem4 ethyl methanesulfonate 0 -- dplvh37 X ray 0 -- dplvR2 ethyl methanesulfonate 0 Yes dplvx18 X ray 0 -- dplvx1 X ray 0 -- dplvx2 X ray 0 -- dplvx3 X ray 0 -- dplvx4 X ray 0 -- dplvx5 X ray 0 -- dply 0 -- dpMFE-1 ethyl methanesulfonate 0 -- dpo14b ethyl methanesulfonate 0 Yes dpo2v2 recombination 0 -- dpo33 0 -- dpo50c spontaneous 0 -- dpo51e U.V. 0 -- dpo spontaneous 0 -- dpoA2 0 -- dpobm X ray 0 -- dpobw spontaneous 0 -- dpodef spontaneous 0 -- dpoDG33 0 -- dpoDG41 0 -- dpoDG53I 0 -- dpoDG56 0 -- dpoDG6 0 -- dpoem10 ethyl methanesulfonate 0 -- dpoem11 ethyl methanesulfonate 0 -- dpoem2 ethyl methanesulfonate 0 -- dpoem9 ethyl methanesulfonate 0 -- dpoh13 X ray 0 -- dpol18b ethyl methanesulfonate 0 Yes dpol2P1 ethyl methanesulfonate 0 Yes dpol36a ethyl methanesulfonate 0 Yes dpol38a ethyl methanesulfonate 0 Yes dpol4 0 -- dpol67b ethyl methanesulfonate 0 Yes dpol71a ethyl methanesulfonate 0 Yes dpol spontaneous 0 -- dpolAS spontaneous 0 -- dpolb20 X ray 0 -- dpolb27 ethyl methanesulfonate 0 -- dpolb42 ethyl methanesulfonate 0 -- dpolCS109 0 -- dpolCS19 ICR 170 0 -- dpolCS41 ICR 170 0 -- dpolCS50 ICR 170 0 -- dpolCS80 ICR 170 0 -- dpolDG9 nitrosomethyl urea 0 -- dpoldx3 X ray 0 -- dpolem1 ethyl methanesulfonate 0 -- dpolem8 ethyl methanesulfonate 0 -- dpolem9 ethyl methanesulfonate 0 -- dpolh10 X ray 0 -- dpolh12 X ray 0 -- dpolh20 X ray 0 -- dpolh21 X ray 0 -- dpolh6 X ray 0 -- dpolh8 X ray 0 -- dpolh9 X ray 0 -- dpolsz24 X ray 0 -- dpolv-12 0 -- dpolv101 0 -- dpolv104A ethyl methanesulfonate 0 Yes dpolv105A ethyl methanesulfonate 0 Yes dpolv12B1 ethyl methanesulfonate 0 Yes dpolv1C5 ethyl methanesulfonate 0 Yes dpolv21C2 0 Yes dpolv27B ethyl methanesulfonate 0 Yes dpolv2 spontaneous 0 -- dpolv2C1 ethyl methanesulfonate 0 Yes dpolv2G1A ethyl methanesulfonate 0 Yes dpolv48a ethyl methanesulfonate 0 Yes dpolv54d U.V. 0 -- dpolv55b spontaneous 0 -- dpolv55c U.V. 0 -- dpolv57g U.V. 0 -- dpolv5B1 ethyl methanesulfonate 0 Yes dpolv61B ethyl methanesulfonate 0 Yes dpolv6 ethyl methanesulfonate 0 Yes dpolv6m X ray 0 -- dpolv89a ethyl methanesulfonate 0 Yes dpolv spontaneous 0 -- dpolva22 ethyl methanesulfonate 0 -- dpolvb12 ethyl methanesulfonate 0 -- dpolvbm X ray 0 -- dpolvCG112 ICR 170 0 -- dpolvCS100 ICR 170 0 -- dpolvCS103 ICR 170 0 -- dpolvCS108 ICR 170 0 -- dpolvCS112 ICR 170 0 -- dpolvCS24 ICR 170 0 -- dpolvCS28 ICR 170 0 -- dpolvCS39 ICR 170 0 -- dpolvCS3 ICR 170 0 -- dpolvCS69 ICR 170 0 -- dpolvCS8 ICR 170 0 -- dpolvCS93 ICR 170 0 -- dpolvCS95 ICR 170 0 -- dpolvD2011A spontaneous 0 Yes dpolvD spontaneous 0 -- dpolvDG10 0 -- dpolvDG20 nitrosomethyl urea 0 -- dpolvDG27 nitrosomethyl urea 0 -- dpolvDG32 0 -- dpolvDG34 0 -- dpolvDG44 0 -- dpolvDG45 0 -- dpolvDG46 0 -- dpolvDG59 0 -- dpolvDG61 nitrosomethyl urea 0 -- dpolvDG62 nitrosomethyl urea 0 -- dpolvDG63 0 -- dpolvDG72 0 -- dpolvDG75 0 -- dpolvem10 ethyl methanesulfonate 0 -- dpolvem11 ethyl methanesulfonate 0 -- dpolvem4 ethyl methanesulfonate 0 -- dpolvem5 ethyl methanesulfonate 0 -- dpolvem6 ethyl methanesulfonate 0 -- dpolvem7 ethyl methanesulfonate 0 -- dpolvem8 ethyl methanesulfonate 0 -- dpolvem9 ethyl methanesulfonate 0 -- dpolvh11 X ray 0 -- dpolvh14 X ray 0 -- dpolvh17 X ray 0 -- dpolvh18 X ray 0 -- dpolvh22 X ray 0 -- dpolvh26 X ray 0 -- dpolvh29 X ray 0 -- dpolvh2 X ray 0 -- dpolvh3 X ray 0 -- dpolvh4 X ray 0 -- dpolvh5 X ray 0 -- dpolvh7 X ray 0 -- dpolvH spontaneous 0 -- dpolvHC234 0 -- dpolvHC39 nitrosomethyl urea 0 -- dpolvHC59 0 -- dpolvHC69 0 -- dpolvM spontaneous 0 -- dpolvP heat-treatment 0 -- dpolvR11 ethyl methanesulfonate 0 Yes dpolvR3 0 Yes dpolvR4 ethyl methanesulfonate 0 Yes dpolvS neutrons 0 -- dpolvSn spontaneous 0 -- dpolvsz28 ethyl methanesulfonate 0 -- dpolvW spontaneous 0 -- dpolvx1 X ray 0 -- dpolvx2 X ray 0 -- dpolvx4 X ray 0 -- dpolvx5 X ray 0 -- dpolXAS1 0 -- dposx66 0 -- dposz66 ethyl methanesulfonate 0 -- dpou U.V. 0 -- dpov51f spontaneous 0 -- dpov51h spontaneous 0 -- dpov52b spontaneous 0 -- dpov56a ethyl methanesulfonate 0 Yes dpov7 0 -- dpov7b ethyl methanesulfonate 0 Yes dpovA12 ethyl methanesulfonate 0 Yes dpovDG27 0 -- dpovDG30 0 -- dpovDG35 0 -- dpovDG37 0 -- dpovDG55 0 -- dpovDG61 0 -- dpovdr spontaneous 0 -- dpOVLR 0 -- dpP1129B spontaneous 0 Yes dpPGE-8 ethyl methanesulfonate 0 -- dpPHE-5 ethyl methanesulfonate 0 -- dpPIE-10 ethyl methanesulfonate 0 -- dpR127 0 -- dpT56e spontaneous 0 -- dpTC-1 0 -- dpTC-2 0 -- dpTC4 recombination 0 -- dpTCM 0 -- dpTFB-31 0 -- dpTFB-6 0 -- dpunspecified X ray 0 -- dpv7 ethyl methanesulfonate 0 -- dpvem3 ethyl methanesulfonate 0 -- dpvM spontaneous 0 -- dpvsz4 ethyl methanesulfonate 0 -- dpvW spontaneous 0 -- dpw18 0 -- dpw3 0 -- dpw8 0 --
Alleles Carried on Transgenic Constructs ( 21 )
For All Alleles Carried on Transgenic Constructs Show
Allele of dp Class Mutagen Stocks Known lesion dpGD10420 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes dpGD10421 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes dpGD10345 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpGD10422 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpGD10423 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpGD4443 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpHMS01537 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpHMS01561 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpHMS01580 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpJF03166 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes dpGD10346 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpGD889 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpHMS01633 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpHMS01658 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.15637R 0 -- dpNIG.31724R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.31725R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.31726R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.31727R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.31964R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dpNIG.31968R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)dp-cl-h1 (Szidonya and Reuter, 1988) Df(2L)dp-cl-h2 (Szidonya and Reuter, 1988) Df(2L)dp-cl-h3 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)dp-h19 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009, Mathew et al., 2009) Df(2L)dp-h24 (Wilkin et al., 2000, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) Df(2L)dp-h25 (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988, Mathew et al., 2009, Mathew et al., 2009) Df(2L)dp-h28 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) Df(2L)ED250 (Mathew et al., 2009) Df(2L)ED250A (Mathew et al., 2009) Df(2L)ED251 (Mathew et al., 2009) Df(2L)ED252 (Mathew et al., 2009) Df(2L)ED262 (Mathew et al., 2009) Df(2L)ed-dp (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)Exel8011 (Ryder, 2004.4.26) Df(2L)M24F11 (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) Df(2L)M24F-B (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Curry, 1939) Df(2L)M24F-C (Curry, 1939) Df(2L)NG6 (Omelyanchuk, 1991) Df(2L)sc19-1 (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) Df(2L)sc19-3 (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) Df(2L)sc19-6 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-11 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-13 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) In(2L)dp-1 (Wilkin et al., 2000) In(2L)dp-2 (Wilkin et al., 2000) In(2L)dpolvR (Wilkin et al., 2000) In(2L)dppd6 (Wilkin et al., 2000) In(2L)TFB-6 (Wilkin et al., 2000) In(2L)TFB-31 (Wilkin et al., 2000) T(2;3)dp5 (Wilkin et al., 2000) T(2;3)dpD (Wilkin et al., 2000, del Campo, 1963) T(2;3)Jazz-12 (Wilkin et al., 2000) T(Y;2)dp61d (Thompson, 1963) T(Y;2)R127 (Wilkin et al., 2000) Tp(2;3)dph27 (Wilkin et al., 2000) Ts(YSt;4Rt)J96+Ts(2Lt;4Lt)J96+Ts(YSt;2Rt)B137 (Kotarski et al., 1983)
Not disrupted in	Df(2L)2802 (Kotarski et al., 1983) Df(2L)cl1 (Kotarski et al., 1983) Df(2L)cl2 (Kotarski et al., 1983) Df(2L)cl7 (Kotarski et al., 1983) Df(2L)dp-h24 (Mathew et al., 2009) Df(2L)dp-h28 (Bryant et al., 1988, Mathew et al., 2009) Df(2L)ed1 (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) Df(2L)ed2 (Reuter and Szidonya, 1983) Df(2L)ED3006-2L (Mathew et al., 2009, Mathew et al., 2009) Df(2L)Exel6010 (Mathew et al., 2009, Mathew et al., 2009) Df(2L)Exel9062 (Mathew et al., 2009, Mathew et al., 2009) Df(2L)Gpdh75 (Kotarski et al., 1983) Df(2L)Gpdh78 (Kotarski et al., 1983) Df(2L)GpdhA (Kotarski et al., 1983) Df(2L)M24F-B (Bryant et al., 1988) Df(2L)sc19-4 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-5 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-10 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)sc19-12 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)tkv2 (Reuter and Szidonya, 1983) Df(2L)tkv3 (Reuter and Szidonya, 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Duplicated in	Dp(2;1)B19 (Bryant et al., 1988) Dp(F2L;2)NG6 (Omelyanchuk, 1991) Ts(2Lt;4Lt)b (Morgan, 1947)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD889} NA P{GD4443} NA P{GD10345} NA P{GD10346} NA P{GD10420} NA P{GD10421} NA P{GD10422} NA P{GD10423} NA P{NIG.31724R} NA P{NIG.31725R} NA P{NIG.31726R} NA P{NIG.31727R} NA P{NIG.31964R} NA P{NIG.31968R} NA P{TRiP.HMS01537} NA P{TRiP.HMS01561} NA P{TRiP.HMS01580} NA P{TRiP.HMS01633} NA P{TRiP.HMS01658} NA P{TRiP.JF03166} NA characterization construct P{NIG.15637R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions blood{}dpov1 NA P{GT1}HP6BG01429 NA PBac{681.P.FSVS-1}dpCPTI001769 NA PBac{PB}dpc00648 NA PBac{PB}dpc01324 NA PBac{PB}dpc06378 NA roo{}dpv2 NA roo{}dpv NA insertion of enhancer trap binary system Mi{ET1}dpMB00453 No
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
apposition of dorsal and ventral imaginal disc-derived wing surfaces inferred from mutant phenotype (Prout et al., 1997) chitin-based cuticle attachment to epithelium inferred from mutant phenotype (Bokel et al., 2005) chitin-based embryonic cuticle biosynthetic process inferred from mutant phenotype (Bokel et al., 2005) lateral inhibition inferred from mutant phenotype (Mummery-Widmer et al., 2009) open tracheal system development inferred from mutant phenotype (Jazwinska et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
4 iron, 4 sulfur cluster binding inferred from electronic annotation with InterPro:IPR003651 (FlyBase Curators et al., 2004-) calcium ion binding inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 (FlyBase Curators et al., 2004-) endonuclease activity inferred from electronic annotation with InterPro:IPR003651 (FlyBase Curators et al., 2004-) extracellular matrix structural constituent inferred from sequence model (Syed et al., 2008) serine-type endopeptidase inhibitor activity inferred from electronic annotation with InterPro:IPR000737 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
extracellular matrix inferred from sequence model (Syed et al., 2008) proteinaceous extracellular matrix non-traceable author statement (Baron et al., 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions dp allele Gene References dpo2 su(dpov) (Kjaer, 1989) dpoh13 l(2)25Ca (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) dpolv Me (Lindsley and Grell, 1968) dpov1 su(dpov) (Kjaer, 1989) dpunspecified l(2)25Ca (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) unspecified Cma   e(dpv)   Me   Psn (Mahoney et al., 2006) rho (Sturtevant and Bier, 1995)
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0053196 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 318824
Orthologs
OrthoDB Orthologs (136) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6BRX4Z Dipteran inclusive ortholog search EOG6GXFVN Insect inclusive ortholog search EOG6547TC Arthropod inclusive ortholog search EOG64XGXK Metazoa inclusive ortholog search EOG6RZ9RS
Orthologs in Drosophila Species (EOG6BRX4Z)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\e(y)3     Drosophila melanogaster fruit fly  Dmel\CG32676     Drosophila melanogaster fruit fly  Dmel\dac     Drosophila melanogaster fruit fly  Dmel\tyf     Drosophila melanogaster fruit fly  Dmel\Cpr64Ad     Drosophila melanogaster fruit fly  Dmel\CG10915     Drosophila melanogaster fruit fly  Dmel\RhoGAP19D     Drosophila melanogaster fruit fly  Dmel\CG43349     Drosophila melanogaster fruit fly  Dmel\dp     Drosophila melanogaster fruit fly  Dmel\CG32603     Drosophila melanogaster fruit fly  Dmel\nocte     Drosophila melanogaster fruit fly  Dmel\elav     Drosophila melanogaster fruit fly  Dmel\CG7300     Drosophila melanogaster fruit fly  Dmel\NFAT     Drosophila melanogaster fruit fly  Dmel\bif     Drosophila melanogaster fruit fly  Dmel\Aef1     Drosophila melanogaster fruit fly  Dmel\CG16711     Drosophila melanogaster fruit fly  Dmel\Vsx1     Drosophila melanogaster fruit fly  Dmel\sbb     Drosophila melanogaster fruit fly  Dmel\CG30069     Drosophila melanogaster fruit fly  Dmel\sens-2     Drosophila melanogaster fruit fly  Dmel\CG8157     Drosophila melanogaster fruit fly  Dmel\Muc12Ea     Drosophila melanogaster fruit fly  Dmel\Samuel     Drosophila melanogaster fruit fly  Dmel\CG15894     Drosophila melanogaster fruit fly  Dmel\CG32767     Drosophila simulans   Dsim\GD22700   Y Drosophila erecta   Dere\GG24368   Y Drosophila yakuba   Dyak\GE14706 Y Y Drosophila ananassae   Dana\GF23960   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA26108 Y Y Drosophila persimilis   Dper\GL14154   Y Drosophila virilis   Dvir\GJ17387   Y Drosophila mojavensis   Dmoj\GI17886 Y Y Drosophila grimshawi   Dgri\GH13743 Y Y
Orthologs in non-Drosophila Dipterans (EOG6GXFVN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012909 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000819 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012905 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009265 Y Anopheles gambiae Malaria mosquito  Agam\AGAP010021 Y Anopheles gambiae Malaria mosquito  Agam\AGAP010024 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013285 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ005058 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004536 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ012484 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015316 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ007969 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ002709 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ007483 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015312 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015311 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006893 Y
Orthologs in non-Dipteran Insects (EOG6547TC)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB41255 Y Apis mellifera Western honey bee  Amel\GB43208 Y Apis mellifera Western honey bee  Amel\GB43666 Y Apis mellifera Western honey bee  Amel\CPR2 Y Apis mellifera Western honey bee  Amel\GB52999 Y Apis mellifera Western honey bee  Amel\LOC551587 Y Apis mellifera Western honey bee  Amel\GB55781 Y Apis mellifera Western honey bee  Amel\GB42621 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004953 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG036228 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008772 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004406 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG000786 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006740 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG035759 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG009060 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG034456 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013086 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG027795 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG032807 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008673 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016473 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004397 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005049 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001062 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004225 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008627 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG029848 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG014054 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008994 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007076 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14778 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14777 Y Atta cephalotes Leafcutter ant  Acep\ACEP23948 Y Atta cephalotes Leafcutter ant  Acep\ACEP23943 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO16689 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12372 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12371 Y Linepithema humile Argentine ant  Lhum\LH24821 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB25725 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB27161 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB27158 Y Solenopsis invicta Red fire ant  Sinv\SINV24596 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI060717 Y Bombyx mori Silkmoth  Bmor\BGIBMGA001358 Y Bombyx mori Silkmoth  Bmor\CPG33 Y Bombyx mori Silkmoth  Bmor\BGIBMGA003481 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011157 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006856 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007313 Y Bombyx mori Silkmoth  Bmor\BGIBMGA010134 Y Bombyx mori Silkmoth  Bmor\BGIBMGA002715 Y Bombyx mori Silkmoth  Bmor\BGIBMGA001620 Y Bombyx mori Silkmoth  Bmor\BGIBMGA012308 Y Bombyx mori Silkmoth  Bmor\BGIBMGA005012 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014578 Y Tribolium castaneum Red flour beetle  Tcas\TC011986 Y Tribolium castaneum Red flour beetle  Tcas\TC009709 Y Tribolium castaneum Red flour beetle  Tcas\Ubx Y Tribolium castaneum Red flour beetle  Tcas\TC011154 Y Tribolium castaneum Red flour beetle  Tcas\TC013169 Y
Orthologs in non-Insect Arthropods (EOG64XGXK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\petN Y Daphnia pulex Water flea  Dpux\JGI_V11_332869 Y Ixodes scapularis Deer tick  Isca\ISCW020313 Y
Orthologs in non-Arthropod Metazoa (EOG6RZ9RS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014572gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026550gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006001gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006000gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016681gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004895gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024374gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015008gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020905gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018275gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019854gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016807gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026651gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021044gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_027006gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_004845gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016555gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_026649gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021866gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_020968gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (5) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM18084 Drosophila yakuba Dyak\GE14706 Drosophila pseudoobscura pseudoobscura Dpse\GA26108 Drosophila mojavensis Dmoj\GI17886 Drosophila grimshawi Dgri\GH13743
Stocks & Reagents
Stocks Listed in FlyBase ( 393 )
Bloomington	276 dpov1 281 dpovN 280 dpolvR/SM5 278 dplv1 b1/SM5
Harvard	- PBac{PB}dpc00648
Kyoto	101466 dpoA4 105826 dpov1 106423 dpD/SM1 105830 dpolvR/SM5 108763 Df(2R)nap2, dpv/CyO 105828 dplv1 b1/SM5
VDRC	v44029 w1118; P{GD4443}v44029
	More stocks available...
Genomic Clones ( 3 )
	BACR04C12 BACR28K16 BACR37J18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 95 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD02173
Other clones	MIP03491
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04178 GH18378 GH28774 LP02053 LP08904 LP17211 LP23991 RE59201 RH17615 RH29680 RH55720 RH60410 SD07468 SD13746
Other clones	DMG3-chr2L.519.pred.a DMG5-chr2L.9.001.pred.a DMG7-chr2L.9.001.pred.a EC00969 EC28716 EC053302 EK026953 EK056921 EK061758 EK076511 EK091903 EK097064 EK194209 EK196145 EK208961 EK223757 EK232049 EK236556 EK238802 EK249210 EK253533 EK264404 EK267140 EK268304 EK268457 EK271220 EK276450 EK279637 EK292118 EK292652 EN00446 EN00624 EN00914 EN00935 EN01353 EN01832 EN02401 EN02405 EN03344 EN03346 EN03363 EN03464 EN04424 EN04442 EN04650 EN05153 EN05505 EN06027 EN06605 EN06762 EN07828 EN07942 EN08158 EN08450 EN09523 EN10904 EN13728 EN13920 EN14449 EN14505 EN14530 EN14637 EN14911 EN15015 EN16042 EN16064 EN16245 EN16246 EN16464 EN16901 EN17150 EP03522 EP08215 EP09940 EP14216 GH291391 IP02624 IP05361 SD06811
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0053196 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318824
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: dp BcDNA:SD02173 (FlyBase Genome Annotators, 2004, FlyBase, 1996-) Source for merge of: dp CG15637 (Ashburner, 2000.8.5)
Additional comments	Source for merge of dp BcDNA:SD02173 was a shared cDNA (date:030728). (FlyBase Genome Annotators, 2004, FlyBase, 1996-) One, two, or three of the phenotypic attributes of dp (o, l, or v) may be expressed in an allele, and alleles are classified according to which attributes they exhibit; the information is generally included in the superscript designation; the order olv is roughly in accord with map order. As a rule, the heteroallelic combination of any two alleles exhibits only phenotypic features common to the two alleles <up>e.g., dpo/dpv is normal, and dpov1/dplv1 exhibits thoracic but not wing abnormalities (Carlson, 1959)</up>. Partial complementations between some pairs of olv and l or lv alleles are exceptions to this rule (Carlson, 1959; Grace, 1980).
Other Comments
	dp is essential for the integrity of the inner layer of the apical extracellular matrix and its link to the the apical surface of the epidermis in the embryo. (Bokel et al., 2005) New annotation (CR33195) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) The dp gene encodes the longest transcript and protein in the Release 3 Genome Annotation. (Misra et al., 2002) The dp gene is extraordinarily large and encodes a 70kb cDNA which codes for a 2.5 MDa extracellular matrix protein. (Wilkin et al., 2002.11.25) 9 alleles of dp have been isolated in a genetic screen for autosomal mutations that produce blisters in somatic wing clones. (Prout et al., 1997) Phenotypic variation of the genetic components underlying oviposition behaviour is analysed using the complete diallel mating design. (Ruiz-Dubreuil and del Solar, 1993) Recombination between alleles belonging to the same or different phenotypic classes allows construction of genetic map with clusters of discontinuously distributed alleles; o and olv alleles found in several clusters, other phenotypic classes confined to a single cluster.   dp alleles have variable effects on wing length and shape and on the thoracic cuticle. Presence of wing phenotype indicated by o = oblique in the allelic designation and of thoracic phenotype by v = vortex or cm = comma. The wing effect is an oblique truncation affecting the margins of the first and second posterior cells in weak alleles and reducing wings to approximately half normal length in extreme genotypes, where the truncation is more nearly perpendicular to the long axis of wing. Margins remain intact; angle between veins L2 and L5 increased and intercrossvein distance decreased. Phenotype resembles rudimentary. Thoracic phenotype comprises five types of hypodermal irregularities: first vortices, second vortices, commas, pre-episternal pits and posterior invagination; all five have the form of pits, eruptions, or raised pits of the cuticle (Metcalfe, 1970). First vortices are hypodermal pits or eruptions located posterolaterally on the scutum; they disrupt the acrostichal rows, resulting in surrounding whorls of microchaete. Second vortices are located anterolaterally on the scutum and resemble first vortices morphologically. Commas are comma-shaped depressions at the anterior margin of the scutum. The pre-episternal pit is in the pre-episternal plate immediately anterior to the sternopleural chaetae, which sometimes exhibit disturbed orientation (Metcalf, 1969). The posterior invagination occurs between the laterotergite plate and the metanotum (Metcalf, 1969); different alleles exhibit different combinations of these traits. Musculature attached to disturbed regions of the cuticle often degenerates (Metcalfe, 1970). Some alleles show reduced body size and small weak legs (dpovh, dpobw females, dpolv/dpov1). Phenotypic expression enhanced by increased temperature during development; wing and thorax effects show dominance when heterozygotes exposed to increased temperatures at 12-16 and 8-10 hr of pupal life, respectively (Blanc and Child, 1940). Normal larvae fed 6-azauracil produce adults with oblique phenocopies; 6-azauracil feeding suppresses dp (Rizki and Rizki, 1965), su(r) enhances the oblique phenotype (Stroman, 1974). The four genotypes studied <up>dpo2, dpovN, dpv2 and dpv; e(dpv)</up> show increased orotate phosphoribosyl transferase activity during third larval instar and enhanced incorporation of labeled glucose into chitin (Blass and Hunt, 1980). Many alleles are lethal when homozygous; they are identified by l in the allelic designation. Lethal stages vary among alleles, e.g., dpolv is embryonic lethal; dplv1 and dplvI die at the egg-larval boundary; dplm homozygotes die primarily at larval ecdysis between the first and second larval instar with some death at hatching and at ecdysis of second-instar larvae; dpobm homozygotes die mostly at hatching but a few die during first and second larval instars (Metcalfe, 1971). In Me/+ heterozygotes, many dp alleles show a dominant oblique effect when heterozygous for dp+ and dp; dpv is an exception (Carlson, 1959). dpv homozygotes normal; show thoracic phenotype only if third chromosomes homozygous for e(dpv).
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001258946 NM_001258947 NM_001258950 NM_001273101 NM_001273102 NM_001273103 NM_001273104 NM_001273105 NM_001273106 NM_001273107 NM_001273108 NM_001273109 NM_001273110 NM_001273111 NM_001273112 NM_001273113 RefSeq (Proteins) • NP_001245875 NP_001245876 NP_001245879 NP_001260030 NP_001260031 NP_001260032 NP_001260033 NP_001260034 NP_001260035 NP_001260036 NP_001260037 NP_001260038 NP_001260039 NP_001260040 NP_001260041 NP_001260042 DDBJ / EMBL / GenBank • AAF24502 AAM52754 AAN10358 AAN10358.2 AAN10358.3 AF214523 AFH03551 AFH03552 AFH03555 AGB92566 AGB92567 AGB92568 AGB92569 AGB92570 AGB92571 AGB92572 AGB92573 AGB92574 AGB92575 AGB92576 AGB92577 AGB92578 AI295308 AI531228 AY122242 CZ467077 CZ470643 Entrez Gene - A searchable database of RefSeq genes. • 318824 UniProtKB/TrEMBL • Q8IQ18 Q8MQX8 Q9U3W7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Green fluorescent protein-like (IPR023413) Complement Clr-like EGF domain (IPR026823) Epidermal growth factor-like domain (IPR000742) EGF-like calcium-binding, conserved site (IPR018097) Endonuclease III-like, iron-sulphur cluster loop motif (IPR003651) EGF-type aspartate/asparagine hydroxylation site (IPR000152) Cysteine-rich repeat (IPR006150) EGF-like calcium-binding (IPR001881) Insulin-like growth factor binding protein, N-terminal (IPR009030) Zona pellucida domain (IPR001507) EGF-like, conserved site (IPR013032) Follistatin-like, N-terminal (IPR003645) Proteinase inhibitor I7, squash (IPR000737) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1OIG BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • SD02173
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0053196 DRSC - Results from RNAi screens. • FBgn0053196 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053196 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33196-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0053196 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 318824 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 318824 modMine - Data generated by the modENCODE project. • FBgn0053196
Synonyms & Secondary IDs ( 29 )
Reported As
Symbol Synonym	BcDNA:SD02173   CG15637 (Ashburner, 2000.8.5, ) CG31724   CG31725   CG31726   CG31727   CG31964   CG31965   CG31966   CG31967   CG31968   CG33000   CG33086   CG33196 (Syed et al., 2008, Carmon et al., 2007, Fernandes et al., 2010, Beltran et al., 2007, Ni et al., 2011.7.19) CR33195   CT35799 (Hynes and Zhao, 2000) dp (Swanson et al., 2009, Kandasamy et al., 2007, Mahoney et al., 2006, Bokel et al., 2005, Syed et al., 2008, Von Ohlen et al., 2012, Olguín et al., 2011, Larschan et al., 2012, Joppich et al., 2009, Ida et al., 2009, Dworkin et al., 2009, Witsell et al., 2009, Mathew et al., 2009, Carmon et al., 2010, Apger et al., 2010, Drysdale, 2003, Wasbrough et al., 2010, Holderbaum et al., 2012.4.9, Bilousov et al., 2012, Japanese National Institute of Genetics, 2012.5.21) Dp (Boekel and Brown, 2001, Doggett et al., 2007, Sakaidani et al., 2011) DP (Royzman et al., 1997, Rees et al., 2011) DPY (Carmon et al., 2010) l(2)24Fd   Mur24F (Syed et al., 2008) olvD   Q8IQ18_DROME (Fukuyama et al., 2012) SP460 (Serano, 1999.12.13, )
Name Synonym	dumpy (Swanson et al., 2009, Prout et al., 1997, MacIntyre et al., 2007, Carmon et al., 2007, Bokel et al., 2005, Von Ohlen et al., 2012, Van Gelder, 2006, Grushko et al., 2008, Carmon and MacIntyre, 2008, Carmon et al., 2007, Carmon et al., 2010, Greil et al., 2007, Joppich et al., 2009, Ida et al., 2009, Mathew et al., 2009, Fernandes et al., 2010, Carmon et al., 2010, Carmon et al., 2010, Apger et al., 2010, Jung et al., 2010) Dumpy (Boekel and Brown, 2001, Syed et al., 2008, Rees et al., 2011, Sakaidani et al., 2011) fibrillin-like (Hynes and Zhao, 2000) Mucin related 24F (Syed et al., 2008)
Secondary FlyBase IDs
	FBgn0000488 FBgn0029129 FBgn0031612 FBgn0051724 FBgn0051725 FBgn0051726 FBgn0051727 FBgn0051964 FBgn0051965 FBgn0051966 FBgn0051967 FBgn0051968 FBgn0053000 FBgn0053195 FBgn0062896 FBgn0063623
References ( 207 )
Generate a list of	All references relating to this gene ( 207 )
List References by type	Research paper  ( 131 ) Supplementary material  ( 8 ) Review  ( 11 ) Personal communication to FlyBase  ( 23 ) Abstract  ( 20 ) FlyBase analysis  ( 5 ) DNA/RNA sequence record  ( 1 ) Stock list  ( 3 ) Website  ( 1 ) Book  ( 2 ) Curated genome annotation  ( 2 )
Recent research papers ( 8 )
	Bilousov et al., 2012, genesis 50(7): 525--533 Role of the gene Miniature in Drosophila wing maturation. [FBrf0218938] Chmielewski et al., 2012, Chromosoma 121(6): 585--596 Drosophila Psf2 has a role in chromosome condensation. [FBrf0220143] Fukuyama et al., 2012, J. Proteomics 75(15): 4610--4619 On-bead tryptic proteolysis: An attractive procedure for LC-MS/MS analysis of the Drosophila caspase 8 protein complex during immune response against bacteria. [FBrf0218992] Larschan et al., 2012, PLoS Genet. 8(7): e1002830 Identification of Chromatin-Associated Regulators of MSL Complex Targeting in Drosophila Dosage Compensation. [FBrf0219020] Von Ohlen et al., 2012, Infect. Immun. 80(10): 3576--3586 Identification of Critical Host Mitochondrion-Associated Genes during Ehrlichia chaffeensis Infections. [FBrf0219421] Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Rees et al., 2011, Mol. Cell. Proteomics 10(6): M110.002386 In Vivo Analysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry. [FBrf0213845] Sakaidani et al., 2011, Nat. Commun. 2: 583 O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions. [FBrf0217928] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...