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Gene Dmel\CG33213

General Information
Symbol	Dmel\CG33213	Species	D. melanogaster
Name		Annotation symbol	CG33213
Feature type	protein_coding_gene	FlyBase ID	FBgn0053213
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	CG12260
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	98B6-98B6	Sequence location	3R:23,743,904..23,745,195 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG33213 (FBgn0053213). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1628445_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG33213. Gene sequence location is 3R:23743904..23745195.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 98B6-98B6   Limits computationally determined from genome sequence between P{PZ}btzrL203 and P{PZ}l(3)0648706487
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG33213 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG33213-RA FBtr0085271  NM_176572   1292   341
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG33213-PA   FBpp0084640   38.7   341   10.16     NP_788749   AAO41605
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142018   AA142019   AA538982   AE014297 AAO41605   AW942490   AY061248 AAL28796   BE978512   BF488033   BF490479   BF493085   BF493086   BI231840   BI351950   BI355883   BI374821   BT022222   BT022741   BT022747   BT022755   BT022782   BT022865   BT022895   BT124884   CO291920   CO331516   EC205130   EL882938   EL882939   GH754407   GH755193   GH758421   GH758987   GH759923   GH760448   GH780666   GH795065   GH799041   GH799986   GH846412   GH861884   GH864090   GH875736   GH887684   GH890393   GH891900   GH894264   GH902989   GH911138   GH915366   GH918191   GH920109   GH926264   GH927461   GH928608   GH931208   GH942612
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VAY8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium organism | ubiquitous   (Fisher et al., 2012) ventral ectoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   central brain primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    121.275 Larval Midgut    14.3 Larval Hindgut    20.8 Larval Malpighian Tubules    8.2 Larval Fat Body    9.9 Larval Salivary Gland    13.9 Larval Trachea    34.05 Larval Carcass    20.7 Adult Head    13.4 Adult Eye    25.05 Adult Brain    29.1 Adult Thoracic-Abdominal Ganglion    24.6 Adult Crop    13.5 Adult Midgut    5.3 Adult Hindgut    13.9 Adult Malpighian Tubules    5.4 Adult Fat Body    5.8 Adult Salivary Gland    3.9 Adult Heart    8.75 Adult VirginFemale Spermatheca    18.3 Adult InseminatedFemale Spermatheca    14.4 Adult Ovary    124.5 Adult Testis    40.9 Adult Male Accessory Gland    21.8 Adult Carcass    8.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    no informative data   NA  Brain    29.1   121.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    24.6   NA  Crop    no informative data   no informative data  Midgut    5.3   no informative data  Hindgut    no informative data   8.2  Malpighian Tubules    5.4   9.9  Fat Body    5.8   no informative data  Salivary Gland    3.9   NA  Heart    8.75   34.05  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    124.5   NA  Testis    40.9   NA  Male Accessory Gland    no informative data   no informative data  Carcass    8.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    9 central nervous system, pupae P8    3 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    1 digestive system, 20-day adult    2 fat body, larvae L3 wandering    0 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    4 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    20 ovary, mated 4-day female    11 testis, mated 4-day male    17 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (29) embryo 02-04hr    19 embryo 04-06hr  (30) embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  29 embryo 02-04hr    19 embryo 04-06hr  30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    19 embryo 04-06hr    30 embryo 06-08hr    19 embryo 08-10hr    14 embryo 10-12hr    9 embryo 12-14hr    5 embryo 14-16hr    3 embryo 16-18hr    2 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    3 larva L2    2 larva L3 12hr old    2 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    7 pupae 2d postWPP    3 pupae 3d postWPP    2 pupae 4d postWPP    2 adult male 01day    2 adult male 05day    3 adult male 30day    3 adult female 01day    5 adult female 05day    11 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    10 embryonic 1182-4H    9 embryonic GM2    8 embryonic Kc167    6 embryonic S1    10 embryonic S3    6 leg disc CME L1    11 wing disc CME-W2    8 wing disc ML-DmD8    6 wing disc ML-DmD9    7 wing disc ML-DmD16-c3    9 wing disc ML-DmD21    9 wing disc ML-DmD32    7 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    8 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    7 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    6 ovary fGS/OSS    6 ovary OSC    7 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    1 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    3 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    10 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    6 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_06
External Data & Images
Linkouts	BDGP expression data • LD18667 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33213-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG33213 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG33213 Class Mutagen Stocks Known lesion CG33213GD17461 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG33213JF03394 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG33213KK112573 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD17461} NA P{KK112573} NA P{TRiP.JF03394} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
	There is no information supporting a biological process term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from sequence or structural similarity with InterPro:IPR007087 (FlyBase Genome Annotators, 2004) zinc ion binding inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with InterPro:IPR007087 (FlyBase Genome Annotators, 2004)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG33213 - CG7911 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG33213 - FK506-bp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG33213 - Nlp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG33213 - Prosα5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG33213 - ctp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG33213 - eIF6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG33213 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 77525 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0053213 DroID - A comprehensive database of gene and protein interactions. • FBgn0053213 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 338395
Orthologs
OrthoDB Orthologs (11) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6V9V9Q Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6V9V9Q)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG33213     Drosophila simulans   Dsim\GD18052 Y   Drosophila sechellia   Dsec\GM16315 Y   Drosophila erecta   Dere\GG12086 Y   Drosophila yakuba   Dyak\GE10532 Y   Drosophila ananassae   Dana\GF18682 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17373 Y   Drosophila persimilis   Dper\GL13758 Y   Drosophila willistoni   Dwil\GK11313 Y   Drosophila virilis   Dvir\GJ10674 Y   Drosophila mojavensis   Dmoj\GI10731 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD18052 Drosophila sechellia Dsec\GM16315 Drosophila erecta Dere\GG12086 Drosophila yakuba Dyak\GE10532 Drosophila ananassae Dana\GF18682 Drosophila pseudoobscura pseudoobscura Dpse\GA17373 Drosophila persimilis Dper\GL13758 Drosophila willistoni Dwil\GK11313 Drosophila virilis Dvir\GJ10674 Drosophila mojavensis Dmoj\GI10731
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	29458 y1 v1; P{TRiP.JF03394}attP2
VDRC	v103517 P{KK112573}VIE-260B v50341 w1118 P{GD17461}v50341
Genomic Clones ( 1 )
	BACR11P22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 51 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP12431 IP12531 IP12731 IP14435 IP14535 IP14635 IP14735 LD18667
Other clones	DPiM_LD18667 MIP03818
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT23281 AT26958 GM16949 RE24379 RE62490
Other clones	273031 AT01348 bs78g02 CK00122 EK198806 EK300033 GM32760 IP12631 RP003063136 RP003155162 RP003176132 RP003180142 RP003198471 RP003215721 RP003228895 RP003274585 RP003277001 RP003288950 RP003291198 RP003307610 RP003327515 RP003336072 RP003348698 RP003391633 RP003411123 RP003432833 RP003463067 RP003530877 RP003558081 RP003573062 RP003597374 RP003606001 RP003613249 RP003625808 RP003628684 RP003653573
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0053213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 338395
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	"CG33221" resembles a retrotransposed, intronless copy of CG33213. (Hogan and Bettencourt, 2009) FlyBase curator comment: The symbol "CG12260" has been used erroneously in FlyBase to name 2 separate annotations (one on chromosome X, the other on arm 3R) in different releases of the genome annotation. The two annotations have been renamed to avoid confusion; they are CG33221 (on the X) and CG33213 (on 3R). CG33213 was labelled "CG12260" in releases 1 and 2, was not annotated in release 3.0 and was labelled "CG33213" in 3.1 of the genome annotation. CG33221 was a new annotation in release 3.1 of the genome annotation, when it was mis-labelled "CG12260". (FlyBase Genome Annotators, 2004)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_176572 RefSeq (Proteins) • NP_788749 DDBJ / EMBL / GenBank • AA538982 AAL28796 AAO41605 AW942490 AY061248 Entrez Gene - A searchable database of RefSeq genes. • 338395 UniProtKB/TrEMBL • Q9VAY8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD18667
Linkouts
	BioGRID - A database of protein and genetic interactions • 77525 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0053213 DroID - A comprehensive database of gene and protein interactions. • FBgn0053213 DRSC - Results from RNAi screens. • FBgn0053213 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053213 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33213-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0053213 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 338395 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 338395 modMine - Data generated by the modENCODE project. • FBgn0053213
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG12260 (Anholt and Mackay, 2001, Asha et al., 2003, ) CG33213 (Keleman et al., 2009.8.5, Perkins et al., 2009, Hogan and Bettencourt, 2009)
Name Synonym
Secondary FlyBase IDs
	FBgn0039556
References ( 19 )
Research paper	Hogan and Bettencourt, 2009, J. Mol. Evol. 68(4): 337--350 Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus. [FBrf0207702] Asha et al., 2003, Genetics 163(1): 203--215 Analysis of ras-induced overproliferation in Drosophila hemocytes. [FBrf0155813] Anholt and Mackay, 2001, Behav. Genet. 31(1): 17--27 The genetic architecture of odor-guided behavior in Drosophila melanogaster. [FBrf0138231]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2004, Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. [FBrf0166453] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Lei, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126680]