evolutionarily conserved scaffolding protein - located at presynaptic active zones - presynaptic homeostasis - plays a critical role for the active zone cytomatrix as a substrate for synaptic plasticity
Gene model reviewed during 5.39
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rim using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Rim in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Rim CG7321
Source for merge of: Rim CG7301 CG7305
Rim promotes the accumulation of Ca[2+] channels and synaptic vesicles in the readily releasable pool at release sites of the active zone.
RNAi generated by PCR using primers directed to CG7305 causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.