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Gene Dmel\CG33914

General Information
Symbol	Dmel\CG33914	Species	D. melanogaster
Name		Annotation symbol	CG33914
Feature type	protein_coding_gene	FlyBase ID	FBgn0053914
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	42E5-42E5	Sequence location	2R:2,924,271..2,926,555 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG33914 (FBgn0053914). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed during late larval stages, during early pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: No FlyAtlas data available because no Affy2 ProbeSet aligns to an exon of CG33914. Comments on Affy2 ProbeSet: No relevant information because no Affy2 ProbeSet aligns to an exon of CG33914. Gene sequence location is 2R:2924271..2926555.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA05033 HFA05034 BKN33290
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 42E5-42E5
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG33914 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG33914-RB FBtr0307215     963   189 CG33914-RC FBtr0307216     2117   189
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG33914-PB   FBpp0298044   21.7   189   8.48       CG33914-PC   FBpp0298045   21.7   189   8.48
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name BT125596   EC074385
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0053914    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0053914 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed during late larval stages, during early pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0053914 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6  (118) larva L3 puffstage 7-9  101 white prepupae new    91 white prepupae 12hr  (139) white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day  (137) adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0053914 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6  118 larva L3 puffstage 7-9  101 white prepupae new    91 white prepupae 12hr  139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day  137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    10 embryo 12-14hr    6 embryo 14-16hr    5 embryo 16-18hr    12 embryo 18-20hr    12 embryo 20-22hr    22 embryo 22-24hr    60 larva L1    40 larva L2    31 larva L3 12hr old    28 larva L3 puffstage 1-2    45 larva L3 puffstage 3-6    118 larva L3 puffstage 7-9    101 white prepupae new    91 white prepupae 12hr    139 white prepupae 24hr    81 pupae 2d postWPP    76 pupae 3d postWPP    85 pupae 4d postWPP    34 adult male 01day    63 adult male 05day    80 adult male 30day    137 adult female 01day    23 adult female 05day    15 adult female 30day    21 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053914
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG33914 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG33914 Class Mutagen Stocks Known lesion CG33914KK113290 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Δ42E (Lin et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK113290} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data on: 2006-05-23)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG33914 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0053914
Orthologs
Genome-wide drosophilid orthologs	Dere\GG10778 Dgri\GH20390 Dmoj\GI20048 Dsec\GM20826 Dsim\GD10279 Dyak\GE24268
Curated drosophilid orthologs
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241397 FBgn0202155 FBgn0182052 FBgn0175707 FBgn0127853 FBgn0103083
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v102904 P{KK113290}VIE-260B
Genomic Clones ( 2 )
	BACR29G01 BACR36G11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP26207
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	60470
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0053914 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3772464
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation (CG33914) in release 4.2 of the genome annotation. (FlyBase Genome Annotators, 2005)
External Crossreferences & Linkouts
Sequence Crossreferences
	DDBJ / EMBL / GenBank • AAZ52823 Entrez Gene - A searchable database of RefSeq genes. • 3772464
Other Crossreferences
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0053914 DRSC - Results from RNAi screens. • FBgn0053914 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0053914 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0053914 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3772464 modMine - Data generated by the modENCODE project. • FBgn0053914 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0241397 FBgn0202155 FBgn0182052 FBgn0175707 FBgn0127853 FBgn0103083
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG33914 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 4 )
Research paper	Lin et al., 2005, Proc. Natl. Acad. Sci. USA 102(36): 12831--12836 A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. [FBrf0188263]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
FlyBase analysis	FlyBase Genome Annotators, 2005, Changes affecting gene model number or type in release 4.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 4.2 of the annotated D.melanogaster genome. [FBrf0182792] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]