FlyBase Gene Report: Dmel\CG33914

General Information

Symbol

Dmel\CG33914

Species

D. melanogaster

Name

Annotation Symbol

CG33914

Feature Type

protein_coding_gene

FlyBase ID

FBgn0053914

Gene Model Status

Current

Stock Availability

1 publicly available

Gene Snapshot

Contributions welcome

Other Summaries

Alliance
Auto summary
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:7,036,768..7,039,050 [-]

Recombination map

2-55

RefSeq locus

NT_033778 REGION:7036768..7039050

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (0 terms)

Molecular Function (0 terms)

There is no information supporting a Molecular Function term for this gene. (Based on a review of available data on: 2006-05-23 )

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

There is no information supporting a Biological Process term for this gene. (Based on a review of available data on: 2006-05-23 )

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

There is no information supporting a Cellular Component term for this gene. (Based on a review of available data on: 2006-05-23 )

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Protein of unknown function DUF1091

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CG33914 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.48

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CG33914-RB

FBtr0307215

NM_001032223

961

189

CG33914-RC

FBtr0307216

NM_001259231

2115

189

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

CG33914-PB

FBpp0298044

21.7

189

8.48

NP_001027394

AAZ52823

CG33914-PC

FBpp0298045

21.7

189

8.48

NP_001246160

AFH07915

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

189 aa isoforms: CG33914-PB, CG33914-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Protein of unknown function DUF1091

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

A1Z6U0

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG33914 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG33914_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\CG33914 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\CG33914

View exonic expression by tissue for Dmel\CG33914

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0053914

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of CG33914

Transgenic constructs containing regulatory region of CG33914

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation

Gene disrupted in

Df(2R)Δ42E

(Lin et al., 2005)

Inferred from location

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (0)

No records found.

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (0)

No records found.

Rattus norvegicus (Norway rat) (0)

No records found.

Xenopus tropicalis (Western clawed frog) (0)

No records found.

Danio rerio (Zebrafish) (0)

No records found.

Caenorhabditis elegans (Nematode, roundworm) (0)

No records found.

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190H9X )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila virilis

Drosophila virilis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150BFR )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17013457

Musca domestica

House fly

Mdoa\17025401

Musca domestica

House fly

Mdoa\17013456

Musca domestica

House fly

Mdoa\17009398

Musca domestica

House fly

Mdoa\17020715

Musca domestica

House fly

Mdoa\17013541

Musca domestica

House fly

Mdoa\17016915

Musca domestica

House fly

Mdoa\17014937

Musca domestica

House fly

Mdoa\17022242

Musca domestica

House fly

Mdoa\17027028

Musca domestica

House fly

Mdoa\17007510

Musca domestica

House fly

Mdoa\17017932

Musca domestica

House fly

Mdoa\17008393

Musca domestica

House fly

Mdoa\17022243

Musca domestica

House fly

Mdoa\17008261

Musca domestica

House fly

Mdoa\17014938

Musca domestica

House fly

Mdoa\17006373

Musca domestica

House fly

Mdoa\17005891

Musca domestica

House fly

Mdoa\17022241

Musca domestica

House fly

Mdoa\17014936

Musca domestica

House fly

Mdoa\17025400

Musca domestica

House fly

Mdoa\17024497

Musca domestica

House fly

Mdoa\17024741

Musca domestica

House fly

Mdoa\17025177

Musca domestica

House fly

Mdoa\17024496

Musca domestica

House fly

Mdoa\17016913

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02663

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01523

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_12130

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_05558

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_07940

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_00498

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_03126

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01526

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02847

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02384

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_03128

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_03132

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_13457

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_03127

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_13632

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_02848

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_08398

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_11221

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_12206

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_08723

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01734

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_05559

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_00299

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01521

Mayetiola destructor

Hessian fly

Mdes\Mdes019320

Mayetiola destructor

Hessian fly

Mdes\Mdes017497

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008895

Anopheles gambiae

Malaria mosquito

Agam\AGAP013264

Anopheles gambiae

Malaria mosquito

Agam\AGAP013456

Anopheles gambiae

Malaria mosquito

Agam\AGAP013247

Anopheles gambiae

Malaria mosquito

Agam\AGAP010741

Anopheles gambiae

Malaria mosquito

Agam\AGAP013353

Anopheles gambiae

Malaria mosquito

Agam\AGAP013484

Anopheles gambiae

Malaria mosquito

Agam\AGAP013050

Anopheles gambiae

Malaria mosquito

Agam\AGAP013316

Anopheles gambiae

Malaria mosquito

Agam\AGAP013517

Anopheles gambiae

Malaria mosquito

Agam\AGAP013086

Anopheles gambiae

Malaria mosquito

Agam\AGAP013448

Anopheles gambiae

Malaria mosquito

Agam\AGAP013225

Anopheles gambiae

Malaria mosquito

Agam\AGAP012562

Anopheles gambiae

Malaria mosquito

Agam\AGAP013322

Anopheles gambiae

Malaria mosquito

Agam\AGAP013113

Anopheles gambiae

Malaria mosquito

Agam\AGAP013369

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ014913

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ011796

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ008358

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ014401

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ014912

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ014914

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0DAY )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis florea

Little honeybee

Aflo\2148003859

Apis mellifera

Western honey bee

Amel\GB51382

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP24256

Bombus terrestris

Buff-tailed bumblebee

Bter\15205478

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG012280

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG034548

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007401

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG013251

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG011712

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI38895

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI085592

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0D8R )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Stegodyphus mimosarum

African social velvet spider

Smim\KFM75622.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM71310.1

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (78)

Gene Symbol

Score

Source

Alignment

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

dls

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0053914

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-55

Cytogenetic map

42E5-42E5

Sequence location

2R:7,036,768..7,039,050 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

42E5-42E5

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-55

(FlyBase, 2016)

2-56.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (1)

VDRC

v102904

P{KK113290}VIE-260B

Genomic Clones (21)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (2)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

MIP26207

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0053914

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

60470

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0053914

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

3772464

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Additional comments

Other Comments

New annotation (CG33914) in release 4.2 of the genome annotation.

(FlyBase Genome Annotators, 2005)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 19 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

3772464

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information