Gene Dmel\CG34015

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General Information

Symbol

Dmel\CG34015

Species

D. melanogaster

Name

Annotation symbol

CG34015

Feature type

protein_coding_gene

FlyBase ID

FBgn0054015

Gene Model Status

Current

Stock availability

None publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

14C6-14C6

Sequence location

X:16,341,601..16,342,335 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG34015 (FBgn0054015). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: catalytic activity. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide. Protein features are: HIT-like domain; Histidine triad (HIT) protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1632373_s_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG34015. Gene sequence location is X:16341601..16342335.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

14C6-14C6

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG34015 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.51

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG34015-RA

FBtr0100070

NM_001038759

594

139

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG34015-PA

FBpp0099426

15.9

139

6.96

NP_001033848

ABC67186

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Histidine triad (HIT) protein (IPR001310)

HIT-like domain (IPR011146)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q6IIA4

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		123.6
Larval Midgut		207.4
Larval Hindgut		106
Larval Malpighian Tubules		132.2
Larval Fat Body		141.5
Larval Salivary Gland		109.3
Larval Trachea		86.6
Larval Carcass		98.65
Adult Head		65.4
Adult Eye		119.4
Adult Brain		61.7
Adult Thoracic-Abdominal Ganglion		71.7
Adult Crop		111.5
Adult Midgut		131
Adult Hindgut		84
Adult Malpighian Tubules		63
Adult Fat Body		120.6
Adult Salivary Gland		126.2
Adult Heart		122.1
Adult VirginFemale Spermatheca		125.6
Adult InseminatedFemale Spermatheca		126.6
Adult Ovary		183.8
Adult Testis		101.2
Adult Male Accessory Gland		83.5
Adult Carcass		80.6
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	65.4
NA	Eye	119.4
NA	Brain	61.7
123.6	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	71.7
NA	Crop	111.5
207.4	Midgut	131
106	Hindgut	84
132.2	Malpighian Tubules	63
141.5	Fat Body	120.6
109.3	Salivary Gland	126.2
NA	Heart	122.1
86.6	Trachea	NA
NA	VirginFemale Spermatheca	125.6
NA	InseminatedFemale Spermatheca	126.6
NA	Ovary	183.8
NA	Testis	101.2
NA	Male Accessory Gland	83.5
98.65	Carcass	80.6

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		(31)
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		16
central nervous system, larvae L3		5
central nervous system, pupae P8		7
head, virgin 1-day female		8
head, virgin 4-day female		4
head, virgin 20-day female		8
head, mated 1-day female		3
head, mated 4-day female		5
head, mated 20-day female		7
head, mated 1-day male		5
head, mated 4-day male		7
head, mated 20-day male		7
salivary gland, larvae L3 wandering		3
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		13
digestive system, 1-day adult		6
digestive system, 4-day adult		8
digestive system, 20-day adult		7
fat body, larvae L3 wandering		5
fat body, white prepupae		7
fat body, pupae P8		0
carcass, larvae L3 wandering		6
carcass, 1-day adult		4
carcass, 4-day adult		5
carcass, 20-day adult		8
ovary, virgin 4-day female		31
ovary, mated 4-day female		16
testis, mated 4-day male		12
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		(29)
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		25
embryo 02-04hr		29
embryo 04-06hr		22
embryo 06-08hr		13
embryo 08-10hr		16
embryo 10-12hr		9
embryo 12-14hr		12
embryo 14-16hr		7
embryo 16-18hr		12
embryo 18-20hr		9
embryo 20-22hr		13
embryo 22-24hr		16
larva L1		13
larva L2		15
larva L3 12hr old		15
larva L3 puffstage 1-2		19
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		16
white prepupae new		14
white prepupae 12hr		14
white prepupae 24hr		12
pupae 2d postWPP		13
pupae 3d postWPP		11
pupae 4d postWPP		8
adult male 01day		10
adult male 05day		9
adult male 30day		6
adult female 01day		9
adult female 05day		22
adult female 30day		21
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		26
Schneider line 2 Sg4		7
embryonic 1182-4H		8
embryonic GM2		10
embryonic Kc167		11
embryonic S1		6
embryonic S3		11
leg disc CME L1		6
wing disc CME-W2		13
wing disc ML-DmD8		6
wing disc ML-DmD9		4
wing disc ML-DmD16-c3		5
wing disc ML-DmD21		3
wing disc ML-DmD32		4
haltere disc ML-DmD17-c3		9
eye-antennal disc ML-DmD11		10
antennal disc ML-DmD20-c5		10
mixed discs ML-DmD4-c1		5
CNS ML-DmBG1-c1		7
CNS ML-DmBG2-c2		8
tumorous blood cells mbn2		12
ovary fGS/OSS		4
ovary OSC		13
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		10
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		14
Cadmium 50 mM 48 hrs, 4-day adult		13
Cadmium 100 mM 48 hrs, 4-day adult		10
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		5
Ethanol 2.5% 3 hrs, larvae L3		10
Ethanol 5% 3 hrs, larvae L3		14
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		18
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		15
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		12
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		25
Rotenone 8 μg 12 hrs, larvae L3		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0054015

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

Stencil:X:16179240:16178679:GENSCAN

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG34015	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG34015	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

There is no information supporting a biological process or cellular component term for this gene.

(Based on a review of available data on: 2006-05-23)

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function

CV term

Evidence

References

catalytic activity

inferred from electronic annotation with InterPro:IPR011146, InterPro:IPR011151

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG34015 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0054015

Orthologs

OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6RNBW0

Dipteran inclusive ortholog search

EOG6SBF7G

Insect inclusive ortholog search

EOG615FBG

Arthropod inclusive ortholog search

EOG6TQJT2

Metazoa inclusive ortholog search

EOG6CGC47

Orthologs in Drosophila Species (EOG6RNBW0)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA25735

Drosophila willistoni

Dwil\GK10717

Drosophila virilis

Dvir\GJ11382

Drosophila mojavensis

Dmoj\GI11708

Drosophila grimshawi

Dgri\GH17587

Drosophila grimshawi

Dgri\GH17102

Orthologs in non-Drosophila Dipterans (EOG6SBF7G)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008486

Anopheles gambiae

Malaria mosquito

Agam\AGAP007577

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000202

Orthologs in non-Dipteran Insects (EOG615FBG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB53297

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG001873

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH23928

Atta cephalotes

Leafcutter ant

Acep\ACEP12909

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO21562

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL10486

Linepithema humile

Argentine ant

Lhum\LH20254

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB21272

Solenopsis invicta

Red fire ant

Sinv\SINV11323

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI000597

Bombyx mori

Silkmoth

Bmor\BGIBMGA011899

Pediculus humanus

Human body louse

Phum\PHUM521150

Tribolium castaneum

Red flour beetle

Tcas\TC030569

Orthologs in non-Insect Arthropods (EOG6TQJT2)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\ND1

Ixodes scapularis

Deer tick

Isca\ISCW016833

Orthologs in non-Arthropod Metazoa (EOG6CGC47)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\hint-3

Danio rerio

Zebrafish

Drer\hint3

Danio rerio

Zebrafish

Drer\OTTDARG00000033548

Xenopus tropicalis

Western clawed frog

Xtro\hint3

Gallus gallus

Domestic chicken

Ggal\HINT3

Mus musculus

House mouse

Mmus\Hint3

Rattus norvegicus

Norway rat

Rnor\Hint3

Homo sapiens

Human

Hsap\HINT3

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\HINT3

AAA Orthologs (8) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila willistoni

Dwil\GK10717

Drosophila mojavensis

Dmoj\GI11708

Drosophila grimshawi

Dgri\GH17102

Stocks & Reagents

Stocks Listed in FlyBase ( 0 )

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 15 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

AM02366

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0054015

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

3885570

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for identity of: CG34015 BP1006

(FlyBase Genome Annotators, 2005)

Source for database merge of

Additional comments

Other Comments

New annotation (CG34015) in release 4.3 of the genome annotation.

(FlyBase Genome Annotators, 2005)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_001038759

RefSeq (Proteins)

•

NP_001033848

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

3885570

UniProtKB/TrEMBL

•

Q6IIA4

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Histidine triad (HIT) protein (IPR001310)

HIT-like domain (IPR011146)

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0054015

DRSC - Results from RNAi screens.

•

FBgn0054015

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0054015

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

Stencil:X:16179240:16178679:GENSCAN

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0054015

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

3885570

modMine - Data generated by the modENCODE project.

•

FBgn0054015

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

BP1006

(Yandell et al., 2005, )

CG34015

unnamed

(Yandell et al., 2005)

Name Synonym

Secondary FlyBase IDs

FBgn0082900

References ( 8 )

Research paper

Yandell et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(5): 1566--1571: A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. [FBrf0183655]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Yandell et al., 2005, Proc. Natl. Acad. Sci. U.S.A.:: Validation of gene predictions in Drosophila melanogaster. Supplementary information for Yandell et al., 2005, Proc. Natl. Acad. Sci. USA 102(5): 1566--1571. [FBrf0183657]

Personal communication to FlyBase

FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]

FlyBase analysis

FlyBase Genome Annotators, 2005, Changes affecting gene model number or type in release 4.3 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in release 4.3 of the annotated D.melanogaster genome. [FBrf0188580]
FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.: Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]