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Gene Dmel\loj

General Information
Symbol	Dmel\loj	Species	D. melanogaster
Name	logjam	Annotation symbol	CG10733
Feature type	protein_coding_gene	FlyBase ID	FBgn0061492
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	l(3)04026, p24
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	65A6-65A6	Sequence location	3L:6,088,087..6,089,617 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene logjam is referred to in FlyBase by the symbol Dmel\loj (CG10733, FBgn0061492). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: oviposition; regulation of post-mating oviposition; reproduction. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: GOLD; Transmembrane emp24 domain-containing protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult fat body, larval salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult salivary gland, adult ovary, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633779_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of loj. Gene sequence location is 3L:6088087..6089617.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 65A6-65A6   Limits computationally determined from genome sequence between P{PZ}vn10567 and P{PZ}loj04026
Experimentally Determined Cytological Location
Cytogenetic map Notes References 65A5-65A6   (determined by in situ hybridisation)   (Spradling et al., 1999) 65A5-65A6     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\loj for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) loj-RD FBtr0301446  NM_168154   1179   237 loj-RE FBtr0301447  NM_139770   1084   237 loj-RF FBtr0301448  NM_168155   1104   237
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein loj-PD   FBpp0290661   26.9   237   6.50     NP_729140   AAF50698 loj-PE   FBpp0290662   26.9   237   6.50     NP_648027   AAN12236 loj-PF   FBpp0290663   26.9   237   6.50     NP_729141   AAN12237
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GOLD (IPR009038) Transmembrane emp24 domain-containing protein (IPR015717)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA804118   AA978511   AE014296 AAF50698   AE014296 AAN12236   AE014296 AAN12237   AI519189   AQ034060   AW943048   AY061384 AAL28932   BI213434   BI353669   BI357822   BI373807   BI635592   BP548026   CL527698   CO181841   CO262959   CO272956   CO288227   EC058657   EC060420   EC196775   EC201470   EC208136   ES689683   EV593088   EV594655   FE863535   FE863602   FE863663   FE863690   FE863691   FE863735   FE863736   FE863849   FE863850   FE863921   FE863922   GH742443   GH743224   GH763125   GH766714   GH779350   GO254482
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VRU2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
cis-Golgi network inferred from direct assay (Boltz et al., 2007) endoplasmic reticulum-Golgi intermediate compartment inferred from direct assay (Boltz et al., 2007)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult fat body, larval salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult salivary gland, adult ovary, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body    1158.4 Larval Salivary Gland    979.2 Larval Trachea    1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland    1781.9 Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body  (1158.4) Larval Salivary Gland  (979.2) Larval Trachea  (1038.375) Larval Carcass  (745.3) Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body  (762) Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca  (652.3) Adult InseminatedFemale Spermatheca  (841.4) Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland  (1781.9) Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body  (1158.4) Larval Salivary Gland    979.2 Larval Trachea  1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland  (1781.9) Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body    1158.4 Larval Salivary Gland    979.2 Larval Trachea    1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland    1781.9 Adult Carcass    313 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body    1158.4 Larval Salivary Gland    979.2 Larval Trachea    1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland    1781.9 Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body  (1158.4) Larval Salivary Gland  (979.2) Larval Trachea  (1038.375) Larval Carcass  745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body  762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca  652.3 Adult InseminatedFemale Spermatheca  (841.4) Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland  (1781.9) Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body  1158.4 Larval Salivary Gland    979.2 Larval Trachea  1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland  (1781.9) Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    282.875 Larval Midgut    266.9 Larval Hindgut    334 Larval Malpighian Tubules    280.3 Larval Fat Body    1158.4 Larval Salivary Gland    979.2 Larval Trachea    1038.375 Larval Carcass    745.3 Adult Head    345.5 Adult Eye    286.35 Adult Brain    143.4 Adult Thoracic-Abdominal Ganglion    138.2 Adult Crop    197.9 Adult Midgut    486.4 Adult Hindgut    185.3 Adult Malpighian Tubules    302.4 Adult Fat Body    762 Adult Salivary Gland    470.9 Adult Heart    379.75 Adult VirginFemale Spermatheca    652.3 Adult InseminatedFemale Spermatheca    841.4 Adult Ovary    337.7 Adult Testis    89.9 Adult Male Accessory Gland    1781.9 Adult Carcass    313 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    345.5   NA  Eye    286.35   NA  Brain    143.4   282.875  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    138.2   NA  Crop    197.9   266.9  Midgut    486.4   334  Hindgut    185.3   280.3  Malpighian Tubules    302.4   1158.4  Fat Body    762   979.2  Salivary Gland    470.9   NA  Heart    379.75   1038.375  Trachea    NA   NA  VirginFemale Spermatheca    652.3   NA  InseminatedFemale Spermatheca    841.4   NA  Ovary    337.7   NA  Testis    89.9   NA  Male Accessory Gland    1781.9   745.3  Carcass    313 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae  (29) digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8  26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female  (27) ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male  (32) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae  29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8  26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female  27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male  32 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    9 central nervous system, pupae P8    11 head, virgin 1-day female    13 head, virgin 4-day female    8 head, virgin 20-day female    19 head, mated 1-day female    6 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    6 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    11 salivary gland, white prepupae    29 digestive system, larvae L3 wandering    14 digestive system, 1-day adult    14 digestive system, 4-day adult    10 digestive system, 20-day adult    11 fat body, larvae L3 wandering    15 fat body, white prepupae    19 fat body, pupae P8    26 carcass, larvae L3 wandering    15 carcass, 1-day adult    11 carcass, 4-day adult    19 carcass, 20-day adult    13 ovary, virgin 4-day female    27 ovary, mated 4-day female    16 testis, mated 4-day male    12 accessory gland, mated 4-day male    32 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr    127 embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (49) embryo 02-04hr  (57) embryo 04-06hr  (63) embryo 06-08hr  (61) embryo 08-10hr  (87) embryo 10-12hr  (127) embryo 12-14hr  (91) embryo 14-16hr  (93) embryo 16-18hr  (67) embryo 18-20hr  (28) embryo 20-22hr    17 embryo 22-24hr    20 larva L1  (32) larva L2  (71) larva L3 12hr old  (53) larva L3 puffstage 1-2  (48) larva L3 puffstage 3-6  (43) larva L3 puffstage 7-9  (49) white prepupae new  (48) white prepupae 12hr  (28) white prepupae 24hr  (35) pupae 2d postWPP  (93) pupae 3d postWPP  (52) pupae 4d postWPP    25 adult male 01day  (29) adult male 05day  (27) adult male 30day  (36) adult female 01day  (40) adult female 05day  (48) adult female 30day  (46) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr  (127) embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr    127 embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr    127 embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (49) embryo 02-04hr  (57) embryo 04-06hr  (63) embryo 06-08hr  (61) embryo 08-10hr  (87) embryo 10-12hr  (127) embryo 12-14hr  (91) embryo 14-16hr  (93) embryo 16-18hr  (67) embryo 18-20hr  28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1  32 larva L2  (71) larva L3 12hr old  (53) larva L3 puffstage 1-2  (48) larva L3 puffstage 3-6  (43) larva L3 puffstage 7-9  (49) white prepupae new  (48) white prepupae 12hr  28 white prepupae 24hr  (35) pupae 2d postWPP  (93) pupae 3d postWPP  (52) pupae 4d postWPP    25 adult male 01day  29 adult male 05day  27 adult male 30day  (36) adult female 01day  (40) adult female 05day  (48) adult female 30day  (46) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr  127 embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    49 embryo 02-04hr    57 embryo 04-06hr    63 embryo 06-08hr    61 embryo 08-10hr    87 embryo 10-12hr    127 embryo 12-14hr    91 embryo 14-16hr    93 embryo 16-18hr    67 embryo 18-20hr    28 embryo 20-22hr    17 embryo 22-24hr    20 larva L1    32 larva L2    71 larva L3 12hr old    53 larva L3 puffstage 1-2    48 larva L3 puffstage 3-6    43 larva L3 puffstage 7-9    49 white prepupae new    48 white prepupae 12hr    28 white prepupae 24hr    35 pupae 2d postWPP    93 pupae 3d postWPP    52 pupae 4d postWPP    25 adult male 01day    29 adult male 05day    27 adult male 30day    36 adult female 01day    40 adult female 05day    48 adult female 30day    46 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (47) Schneider line 2 Sg4  (93) embryonic 1182-4H  (34) embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1  (70) wing disc CME-W2  (38) wing disc ML-DmD8  (32) wing disc ML-DmD9  (27) wing disc ML-DmD16-c3  (27) wing disc ML-DmD21  (60) wing disc ML-DmD32  (32) haltere disc ML-DmD17-c3  26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5  (55) mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (38) CNS ML-DmBG2-c2  (43) tumorous blood cells mbn2  (37) ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (47) Schneider line 2 Sg4  (93) embryonic 1182-4H  (34) embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1  (70) wing disc CME-W2  (38) wing disc ML-DmD8  32 wing disc ML-DmD9  27 wing disc ML-DmD16-c3  27 wing disc ML-DmD21  (60) wing disc ML-DmD32  32 haltere disc ML-DmD17-c3  26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5  (55) mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (38) CNS ML-DmBG2-c2  (43) tumorous blood cells mbn2  (37) ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    47 Schneider line 2 Sg4    93 embryonic 1182-4H    34 embryonic GM2    20 embryonic Kc167    25 embryonic S1    12 embryonic S3    23 leg disc CME L1    70 wing disc CME-W2    38 wing disc ML-DmD8    32 wing disc ML-DmD9    27 wing disc ML-DmD16-c3    27 wing disc ML-DmD21    60 wing disc ML-DmD32    32 haltere disc ML-DmD17-c3    26 eye-antennal disc ML-DmD11    17 antennal disc ML-DmD20-c5    55 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    38 CNS ML-DmBG2-c2    43 tumorous blood cells mbn2    37 ovary fGS/OSS    16 ovary OSC    13 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3  (35) Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3  (29) Ethanol 10% 3 hrs, larvae L3  26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3  (33) Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3  (35) Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3  29 Ethanol 10% 3 hrs, larvae L3  26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3  (33) Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    11 cold shock, 4-day adult    7 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    35 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    23 Ethanol 5% 3 hrs, larvae L3    29 Ethanol 10% 3 hrs, larvae L3    26 Caffeine 1.5 mg/ml 4 hrs, larvae L3    16 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    16 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    12 Rotenone 2 μg 12 hrs, larvae L3    33 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0061492 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10733-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive loj04026 partially lethal - majority die | recessive loj04026 viable (with Df(3L)ZN47) loj04026 viable (with loj00898) loj04026 viable (with loj04026) loj00898 Sterility Allele female sterile loj00898 female sterile (with loj00898) loj04026 female sterile (with loj04026) loj00898 female sterile | recessive loj00898 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of loj Class Mutagen Stocks Known lesion loj04026 P-element activity 1 Yes lojEY03118 P-element activity 1 -- lojf02510 1 -- lojMI05446 1 -- loj00898 P-element activity 0 Yes lojunspecified 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of loj Class Mutagen Stocks Known lesion lojGD4830 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes lojhs.PC in vitro construct - regulatory fusion 0 Yes lojNIG.10733R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes lojScer\UAS.N9d in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)BSC410 (Christensen et al., 2008.4.15) Df(3L)BSC411 (Christensen et al., 2008.4.15) Df(3L)BSC551 (Christensen et al., 2008.7.11) Df(3L)Exel8101 (Ryder, 2004.4.26) Df(3L)ZN47 (Spradling et al., 1999, Carney and Taylor, 2003, BDGP Project Members, 1994-1999)
Not disrupted in	Df(3L)CH12 (Abu-Shumays and Fristrom, 1997)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4830} NA P{NIG.10733R} NA P{UAS-loj.N9d} NA heat-shock construct P{hs-loj.C} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}loj00898 No P{PZ}loj04026 No insertion of mobile activating element P{EPgy2}lojEY03118 NA miscellaneous insertions Mi{MIC}lojMI05446 NA PBac{WH}lojf02510 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
oviposition inferred from mutant phenotype (Carney and Taylor, 2002, Carney and Taylor, 2003) regulation of post-mating oviposition inferred from mutant phenotype (Saleem et al., 2012) reproduction inferred from mutant phenotype (Saleem et al., 2012)
Cellular Component
CV term Evidence References
cis-Golgi network inferred from direct assay (Boltz et al., 2007) endoplasmic reticulum-Golgi intermediate compartment inferred from direct assay (Boltz et al., 2007)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
transport inferred from electronic annotation with InterPro:IPR009038 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR009038 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions loj allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64154 DroID - A comprehensive database of gene and protein interactions. • FBgn0061492 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38698
Orthologs
OrthoDB Orthologs (31) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG69CQTX Dipteran inclusive ortholog search EOG683DDJ Insect inclusive ortholog search EOG6XPPBW Arthropod inclusive ortholog search EOG6K6DM6 Metazoa inclusive ortholog search EOG6RVFKN
Orthologs in Drosophila Species (EOG69CQTX)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\loj     Drosophila simulans   Dsim\GD13935 Y   Drosophila sechellia   Dsec\GM14754 Y   Drosophila erecta   Dere\GG15320 Y   Drosophila yakuba   Dyak\GE21539 Y   Drosophila ananassae   Dana\GF23515 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10530 Y   Drosophila persimilis   Dper\GL15550 Y   Drosophila willistoni   Dwil\GK17263 Y   Drosophila virilis   Dvir\GJ12734 Y   Drosophila mojavensis   Dmoj\GI12612 Y   Drosophila grimshawi   Dgri\GH15831 Y
Orthologs in non-Drosophila Dipterans (EOG683DDJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006560   Anopheles gambiae Malaria mosquito  Agam\AGAP006043   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ000287
Orthologs in non-Dipteran Insects (EOG6XPPBW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\loj   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012112   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10299   Atta cephalotes Leafcutter ant  Acep\ACEP20893   Camponotus floridanus Florida carpenter ant  Cflo\CFLO16194   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13047   Linepithema humile Argentine ant  Lhum\LH22018   Pogonomyrmex barbatus Red harvester ant  Pbar\PB16116   Solenopsis invicta Red fire ant  Sinv\SINV11896   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009625   Bombyx mori Silkmoth  Bmor\BGIBMGA002898   Pediculus humanus Human body louse  Phum\PHUM045400   Tribolium castaneum Red flour beetle  Tcas\TC012624
Orthologs in non-Insect Arthropods (EOG6K6DM6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_45190   Ixodes scapularis Deer tick  Isca\ISCW011849
Orthologs in non-Arthropod Metazoa (EOG6RVFKN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007881gn
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13935 Drosophila sechellia Dsec\GM14754 Drosophila erecta Dere\GG15320 Drosophila yakuba Dyak\GE21539 Drosophila ananassae Dana\GF23515 Drosophila pseudoobscura pseudoobscura Dpse\GA10530 Drosophila persimilis Dper\GL15550 Drosophila willistoni Dwil\GK17263 Drosophila virilis Dvir\GJ12734 Drosophila mojavensis Dmoj\GI12612 Drosophila grimshawi Dgri\GH15831
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	11619 P{PZ}loj04026 ry506/TM3, ryRK Sb1 Ser1 42085 y1 w*; Mi{MIC}lojMI05446/TM3, Sb1 Ser1 16553 y1 w67c23; P{EPgy2}lojEY03118/TM3, Sb1 Ser1
Harvard	- PBac{WH}lojf02510
Genomic Clones ( 1 )
	BACR09G21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 36 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD30746
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM12884 GM24669 LD38695 RE18835 RE44409 RE61227 SD16982
Other clones	9686 76899 CK01.86A.F1 CK01.103C.G3 Dmel_neb_011708_0579_2720 Dmel_neb_012993_0697_2803 EC15078 EK068021 EK086926 EK108949 FGH123C02 RM07465 RM07566 RM07665 RM07765 RM07766 RM07965 RM07966 RM08065 RM08066 RM08165 RM08166 RP01372 RP001006449 RP001006617 RP001021465 RP001027980 RP001054527
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0061492 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38698
Antibody Information
	polyclonal (Boltz et al., 2007)
Other Information
Discoverer
Etymology
	The gene is named "logjam" after the mutant phenotype; in mutant females, one or more mature eggs become lodged within the genital tract, causing a "logjam" of eggs within the female and preventing the release of eggs. (Carney and Taylor, 2003)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: loj CG10733 l(3)04026 (Carney and Taylor, 2003)
Additional comments
Other Comments
	Identification: In a screen for genes involved in female-specific reproductive behaviors. (Carney and Taylor, 2002) Mutations in loj cause the loss of oviposition behavior and the retention of mature eggs in the oviducts and uteruses of mated mutant females. (Carney and Taylor, 2002)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139770 NM_168154 NM_168155 RefSeq (Proteins) • NP_648027 NP_729140 NP_729141 DDBJ / EMBL / GenBank • AA804118 AA978511 AAF50698 AAL28932 AAN12236 AAN12237 AI519189 AQ034060 AW943048 AY061384 BI213434 BI353669 BI357822 BI373807 BI635592 CL527698 Entrez Gene - A searchable database of RefSeq genes. • 38698 UniProtKB/TrEMBL • Q9VRU2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GOLD (IPR009038) Transmembrane emp24 domain-containing protein (IPR015717)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64154 DroID - A comprehensive database of gene and protein interactions. • FBgn0061492 DRSC - Results from RNAi screens. • FBgn0061492 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0061492 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10733-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0061492 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38698 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38698 modMine - Data generated by the modENCODE project. • FBgn0061492
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG10733 (Rehwinkel et al., 2006, Giot et al., 2003, Mosallanejad et al., 2010, Behm-Ansmant et al., 2006) l(3)04026 (Birchler et al., 2001, Berkeley Drosophila Genome Project, 1993.6.1, Abu-Shumays and Fristrom, 1997, Spradling et al., 1999, BDGP Project Members, 1994-1999, ) loj (Carney et al., 2007, Christensen et al., 2008.7.11, Carney et al., 2008, Christensen et al., 2008.4.15, Christensen et al., 2008.4.15, Boltz et al., 2007, T et al., 2008, Boltz and Carney, 2008, Japanese National Institute of Genetics, 2012.5.21) LOJ (Saleem et al., 2012) p24 (Boltz and Carney, 2008, Boltz et al., 2007)
Name Synonym	logjam (Carney and Taylor, 2002, Carney et al., 2007, Carney et al., 2008, Boltz et al., 2007, T et al., 2008, Boltz and Carney, 2008, Port et al., 2011)
Secondary FlyBase IDs
	FBgn0010829 FBgn0035680
References ( 40 )
Generate a list of	All references relating to this gene ( 40 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 4 ) Review  ( 3 ) Personal communication to FlyBase  ( 11 ) Abstract  ( 8 ) FlyBase analysis  ( 1 ) Stock list  ( 1 )
Recent research papers ( 3 )
	Avila et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(12): 4562--4567 A requirement for the neuromodulators octopamine and tyramine in Drosophila melanogaster female sperm storage. [FBrf0217828] Saleem et al., 2012, Mech. Dev. 129(5-8): 177--191 Drosophila melanogaster p24 trafficking proteins have vital roles in development and reproduction. [FBrf0219054] Port et al., 2011, EMBO Rep. 12(11): 1144--1152 A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. [FBrf0216532] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...