Gene Rnor\ANF

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General Information

Symbol

Rnor\ANF

Species

R. norvegicus

Name

atrial natriuretic factor

Annotation symbol

Feature type

engineered_foreign_gene

FlyBase ID

FBgn0066085

Gene Model Status

Not Applicable

Stock availability

1 publicly available

Also Known As

ANF

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

Sequence location

Summary Information

Automatically generated summary

See sections below for more information

The gene atrial natriuretic factor is referred to in FlyBase by the symbol Rnor\ANF (FBgn0066085). It is a engineered_foreign_gene from Rattus norvegicus. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Mapped Features

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

modENCODE Anatomy RNA-Seq

modENCODE Development RNA-Seq

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

Expression Clusters

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of Rnor\ANF	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Rnor\ANF	Class	Mutagen	Stocks	Known lesion
Rnor\ANF^{Scer\UAS.T:Avic\GFP-EMD}		in vitro construct - coding region fusion in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

engineered_foreign_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Rnor\ANF allele

Gene

References

External Data

Linkouts

Orthologs

OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

No orthologs identified

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

No orthologs identified

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Ortholog(s) in Drosophila melanogaster (None identified)

No D. melanogaster orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (0) based on analysis using Dmel annotation version 4.3

No orthologs identified

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

7001

P{UAS-preproANF-EMD}136.3, y¹ w^*

Genomic Clones ( 0 )

cDNA Clones ( 0 )

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

Tag or Foreign Gene Data

Foreign sequence; species == Rattus norvegicus; gene == 'ANF'; UniProt:P01161.

External Crossreferences & Linkouts

Sequence Crossreferences

Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

ANF

(Khodosh et al., 2006, Barkus et al., 2008)

Rnor\ANF

Name Synonym

atrial natriuretic factor

Secondary FlyBase IDs

References ( 20 )

Research paper

Djagaeva et al., 2012, Genetics 192(1): 173--183: Three routes to suppression of the neurodegenerative phenotypes caused by Kinesin heavy chain mutations. [FBrf0219395]
Füger et al., 2012, PLoS Genet. 8(11): e1003066: Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model. [FBrf0220146]
Ile et al., 2012, Development 139(14): 2535--2546: Wunen, a Drosophila lipid phosphate phosphatase, is required for septate junction-mediated barrier function. [FBrf0218686]
Liu et al., 2012, Curr. Biol. 22(22): 2114--2123: Two dopaminergic neurons signal to the dorsal fan-shaped body to promote wakefulness in Drosophila. [FBrf0220041]
Lloyd et al., 2012, Neuron 74(2): 344--360: The p150(Glued) CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini. [FBrf0218160]
Ma et al., 2012, Genetics 190(4): 1299--1308: Membrane phospholipid asymmetry counters the adverse effects of sterol overloading in the Golgi membrane of Drosophila. [FBrf0217992]
Wong et al., 2012, Cell 148(5): 1029--1038: Neuropeptide delivery to synapses by long-range vesicle circulation and sporadic capture. [FBrf0217647]
Loveall and Deitcher, 2010, BMC Dev. Biol. 10(1): 92: The essential role of bursicon during Drosophila development. [FBrf0211836]
Jansen et al., 2009, J. Comp. Neurol. 517(3): 313--332: PICK1 expression in the Drosophila central nervous system primarily occurs in the neuroendocrine system. [FBrf0208848]
Barkus et al., 2008, Mol. Biol. Cell 19(1): 274--283: Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. [FBrf0203182]
Berni et al., 2008, Europ. J. Neurosci. 27(2): 396--407: The axon-guidance roundabout gene alters the pace of the Drosophila circadian clock. [FBrf0202846]
Pack-Chung et al., 2007, Nat. Neurosci. 10(8): 980--989: A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. [FBrf0201241]
Khodosh et al., 2006, Development 133(23): 4655--4665: Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events. [FBrf0195140]
Wen et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(6): 2141--2146: Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity. [FBrf0184235]
Wu et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(37): 13289--13294: Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. [FBrf0188283]
Heifetz and Wolfner, 2004, Proc. Natl. Acad. Sci. U.S.A. 101(16): 6261--6266: Mating, seminal fluid components, and sperm cause changes in vesicle release in the Drosophila female reproductive tract. [FBrf0175095]
Stoleru et al., 2004, Nature 431(7010): 862--868: Coupled oscillators control morning and evening locomotor behaviour of Drosophila. [FBrf0179740]
Rao et al., 2001, J. Neurobiol. 49(3): 159--172: Visualization of neuropeptide expression, transport, and exocytosis in Drosophila melanogaster. [FBrf0141613]

Abstract

Tsarouhas et al., 2006, A. Dros. Res. Conf. 47: 80: Genetic dissection of epithelial maturation in trachea by live imaging. [FBrf0189112]

FlyBase analysis

FlyBase Curators, 1992-, Summary information describing the origin of tags and foreign genes in FlyBase.: Summary information describing the origin of tags and foreign genes in FlyBase. [FBrf0199194]