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Gene MS2\MCP

General Information
Symbol	MS2\MCP	Species	L. Enterobacteria phage MS2
Name	MS2 coat protein	Annotation symbol
Feature type	engineered_foreign_gene	FlyBase ID	FBgn0067412
Gene Model Status	Not Applicable	Stock availability	7 publicly available
Also Known As	mcp
Genomic Location
Chromosome (arm)		Recombination map
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene MS2 coat protein is referred to in FlyBase by the symbol MS2\MCP (FBgn0067412). It is a engineered_foreign_gene from Levivirus Enterobacteria phage MS2. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of MS2\MCP Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of MS2\MCP Class Mutagen Stocks Known lesion MS2\MCPHsp83.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 3 Yes MS2\MCPHsp83.T:Disc\RFP in vitro construct - coding region fusion 2 Yes MS2\MCPScer\UAS.T:Disc\RFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes MS2\MCPScer\UAS.T:Avic\GFP-EGFP,T:Zzzz\nls1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	engineered_foreign_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions MS2\MCP allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	27418 y1 w*; P{UAS-MCP-RFP}8A 7280 y1 w*; P{Hsp83-MCP-GFP}3 27419 y1 w*; P{UAS-MCP-RFP}12A 7278 P{Hsp83-MCP-GFP}11, y1 w* 7279 y1 w*; P{Hsp83-MCP-GFP}5A 9939 y1 w67c23; P{Hsp83-MCP-RFP}12a 9940 y1 w67c23; P{Hsp83-MCP-RFP}4a/CyO
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
Tag or Foreign Gene Data
	Foreign sequence; species == Bacteriophage MS2; gene == 'MCP, MS2 coat protein'; UniProt:P03612.
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	mcp (Kalifa et al., 2009) MCP (Becalska et al., 2011, Sinsimer et al., 2011) ms2 (Diao et al., 2010) MS2\MCP
Name Synonym	MS2 coat protein (Reich et al., 2009)
Secondary FlyBase IDs
References ( 19 )
Research paper	Becalska et al., 2011, Dev. Biol. 349(1): 46--52 Aubergine is a component of a nanos mRNA localization complex. [FBrf0212348] Fan et al., 2011, PLoS ONE 6(5): e20612 Drosophila Ge-1 Promotes P Body Formation and oskar mRNA Localization. [FBrf0213914] Lerit and Gavis, 2011, Curr. Biol. 21(6): 439--448 Transport of germ plasm on astral microtubules directs germ cell development in Drosophila. [FBrf0213255] Sinsimer et al., 2011, Development 138(16): 3431--3440 A late phase of germ plasm accumulation during Drosophila oogenesis requires Lost and Rumpelstiltskin. [FBrf0214542] Diao et al., 2010, Mol. Cell. Neurosci. 45(1): 75--83 SIDL interacts with the dendritic targeting motif of Shal (K(v)4) K(+) channels in Drosophila. [FBrf0211355] Kalifa et al., 2009, Dev. Biol. 326(1): 68--74 Glorund interactions in the regulation of gurken and oskar mRNAs. [FBrf0207042] Lim et al., 2009, J. Cell Biol. 186(3): 333--342 piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. [FBrf0208560] Reich et al., 2009, PLoS ONE 4(3): e4669 miRNA-dependent translational repression in the Drosophila ovary. [FBrf0207452] Brechbiel and Gavis, 2008, Curr. Biol. 18(10): 745--750 Spatial regulation of nanos is required for its function in dendrite morphogenesis. [FBrf0204902] Estes et al., 2008, Mol. Cell. Neurosci. 39(2): 170--179 Fragile X protein controls the efficacy of mRNA transport in Drosophila neurons. [FBrf0207148] Zimyanin et al., 2008, Cell 134(5): 843--853 In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization. [FBrf0206046] Ashraf et al., 2006, Cell 124(1): 191--205 Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. [FBrf0189896] Weil et al., 2006, Dev. Cell 11(2): 251--262 Localization of bicoid mRNA in late oocytes is maintained by continual active transport. [FBrf0193521] Forrest and Gavis, 2003, Curr. Biol. 13(14): 1159--1168 Live imaging of endogenous RNA reveals a diffusion and entrapment mechanism for nanos mRNA localization in Drosophila. [FBrf0160523]
Supplementary material	Brechbiel and Gavis, 2008, Curr. Biol. 18(10): Supplemental Experimental Procedures. [FBrf0208085] Lin et al., 2008, Dev. Biol. 322(2): Drosophila processing bodies in oogenesis. Supplementary data. [FBrf0214680] Ashraf et al., 2006, Cell 124(1): Supplemental Data. [FBrf0198682]
FlyBase analysis	FlyBase Curators, 1992-, Summary information describing the origin of tags and foreign genes in FlyBase. Summary information describing the origin of tags and foreign genes in FlyBase. [FBrf0199194] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]