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Gene Dmel\abz

General Information
Symbol	Dmel\abz	Species	D. melanogaster
Name	abruzzi	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0067854
Gene Model Status	Unannotated	Stock availability	None publicly available
Genomic Location
Chromosome (arm)		Recombination map	3-
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene abruzzi is referred to in FlyBase by the symbol Dmel\abz (FBgn0067854). It is a gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: pole plasm oskar mRNA localization; bicoid mRNA localization. 3 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	3- (Martin et al., 2003)
Left of (cM)
Right of (cM)
Notes	Maps to 3R. (Martin et al., 2003)
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal (with abz7C3-10) abz8B1-12 lethal (with abz8B1-12) abz7C3-10 Phenotype manifest in Allele egg chamber | germline clone abzunspecified oocyte nucleus | germline clone abz7C3-10
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of abz Class Mutagen Stocks Known lesion abz7C3-10 ethyl methanesulfonate 0 -- abz8B1-12 ethyl methanesulfonate 0 -- abzunspecified 0 --
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of abz Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a cellular component or molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
bicoid mRNA localization inferred from mutant phenotype (Martin et al., 2003) pole plasm oskar mRNA localization inferred from mutant phenotype (Martin et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions abz allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5658297
Antibody Information
Other Information
Discoverer
Etymology
	To reflect the fact that many of the mutants isolated in this screen disrupt Avic\GFP-stau localisation to the anterior and/or posterior pole of the oocyte, many of the complementation groups identified in the screen have been named after polar explorers who failed to reach the North or South pole. (Martin et al., 2003)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Identified in a germline clone screen for mutants that are defective in localisation of an Avic\GFP-stau marker in living oocytes. 2 alleles of abz have been identified in the screen. (Martin et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5658297
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	abz
Name Synonym	abruzzi (Martin et al., 2003)
Secondary FlyBase IDs
References ( 2 )
Research paper	Martin et al., 2003, Development 130(17): 4201--4215 The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen. [FBrf0160777]
FlyBase analysis	FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]