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Gene Dmel\Patj

General Information
Symbol	Dmel\Patj	Species	D. melanogaster
Name	Patj	Annotation symbol	CG12021
Feature type	protein_coding_gene	FlyBase ID	FBgn0067864
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	dlt, DPATJ
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	62B4-62B4	Sequence location	3L:1,798,809..1,802,184 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Patj is referred to in FlyBase by the symbol Dmel\Patj (CG12021, FBgn0067864). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein kinase C binding. There is experimental evidence that it is involved in the biological process: adherens junction organization; morphogenesis of follicular epithelium; establishment or maintenance of polarity of follicular epithelium; establishment of planar polarity; photoreceptor cell maintenance; photoreceptor cell morphogenesis. 17 alleles are reported. The phenotype of these alleles is annotated with: ectoderm. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: L27; PDZ/DHR/GLGF. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1630671_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of Patj. Gene sequence location is 3L:1798809..1802184.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Yasugi et al., 2010, Development 137(19): 3193--3203 Sequence features HFA08712 BKN30089
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62B4-62B4   Limits computationally determined from genome sequence between P{PZ}dlt04276 and P{PZ}slsrL182
Experimentally Determined Cytological Location
Cytogenetic map Notes References 62B2-62B4     (Bhat, 1998.11.2) 62B2-62B4     (Bhat, 1998.3.10)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Patj for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Patj-RA FBtr0301625  NM_134317   3258   871 Patj-RB FBtr0072781  NM_167917   3230   871 Patj-RC FBtr0072779  NM_057994   3260   871
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Patj-PA   FBpp0290839   92.9   871   4.58     NP_599144   AAN11498 Patj-PB   FBpp0072664   92.9   871   4.58     NP_728674   AAG22224 Patj-PC   FBpp0072662   92.9   871   4.58     NP_477342   AAF47573
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • PDZ/DHR/GLGF (IPR001478) L27 (IPR004172)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392273   AA817118   AA820077   AA949935   AA950996   AE014296 AAF47573   AE014296 AAG22224   AE014296 AAN11498   AC005557   AF103942 AAD43031   AF132193 AAD34781   AF274350 AAF81829   AI297821   AI388766   AI402651   AI455245   AI512547   AI515653   AI515666   AI518278   AI520099   AI531400   AI533721   BG638530   BI164738   BI165918   BI171990   BI213514   BI227537   BI227652   BI230977   BI232380   BI232420   BI234973   BI236063   BI355993   BI356113   BI369170   BI369533   BI486002   BI566032   BI577724   BI580215   BI585059   BI588254   BI592531   BI592939   BI626446   BI632463   BI640301   CK132160   CK132212   CK659043   CO304262   CO304691   CO307090   CO310108   CO333061   CO340950   EC065240   EC216681   EC237702   EC249380   EC254681   GH739028   GH739299   GH739477   GH739966   GH741248   GH741769   GH741881   GH742715   GH743159   GH743285   GH745693   GH745713   GH746184   GH746738   GH747407   GH747502   GH747581   GH762730   GH763666   GH763714   GH764002   GH764459   GH764746   GH765275   GH765321   GH765869   GH767599   GH768409   GH769342   GH769382   GH779241   GH779625
UniProtKB/Swiss-Prot	Q9NB04
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 6   epithelial cell   • lateral plasma membrane (Lecuyer et al., 2007) epithelium   • lateral plasma membrane (Lecuyer et al., 2007)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference pupal stage   eye photoreceptor cell stalk | apical   (Nam and Choi, 2003)
Additional Descriptive Data
	<e> il <t> E | stage 16 <a> embryonic/larval tracheocyte <s> apicolateral plasma membrane <note> (Paul et al., 2003) <e> il <t> E | stage 16 <a> epithelial cell &&of embryonic/larval salivary gland <s> apicolateral plasma membrane <note> (Paul et al., 2003) <e> il <t> E | stage 16 <a> epidermal cell <s> apicolateral plasma membrane <note> (Paul et al., 2003)
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0067864    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0067864 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0067864 expression level Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3394) embryo 02-04hr  (5274) embryo 04-06hr  (4434) embryo 06-08hr  (3562) embryo 08-10hr  (2933) embryo 10-12hr  (2412) embryo 12-14hr  (1963) embryo 14-16hr  (2339) embryo 16-18hr  (1733) embryo 18-20hr  (1269) embryo 20-22hr  (1422) embryo 22-24hr  (1203) larva L1  (766) larva L2  (790) larva L3 12hr old  (582) larva L3 puffstage 1-2  (593) larva L3 puffstage 3-6  (1020) larva L3 puffstage 7-9  (1185) white prepupae new  (1265) white prepupae 12hr  (1277) white prepupae 24hr  (1395) pupae 2d postWPP  (1451) pupae 3d postWPP  (1112) pupae 4d postWPP  (981) adult male 01day  (1109) adult male 05day  (1363) adult male 30day  (1194) adult female 01day  (1470) adult female 05day  (1929) adult female 30day  (2022) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3394) embryo 02-04hr  (5274) embryo 04-06hr  (4434) embryo 06-08hr  (3562) embryo 08-10hr  (2933) embryo 10-12hr  (2412) embryo 12-14hr  (1963) embryo 14-16hr  (2339) embryo 16-18hr  (1733) embryo 18-20hr    1269 embryo 20-22hr  1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP  1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day  1470 adult female 05day  (1929) adult female 30day  (2022) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0067864 expression level Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3394) embryo 02-04hr  (5274) embryo 04-06hr  (4434) embryo 06-08hr  (3562) embryo 08-10hr  (2933) embryo 10-12hr  (2412) embryo 12-14hr  (1963) embryo 14-16hr  (2339) embryo 16-18hr  (1733) embryo 18-20hr  (1269) embryo 20-22hr  (1422) embryo 22-24hr  (1203) larva L1  (766) larva L2  (790) larva L3 12hr old  (582) larva L3 puffstage 1-2  (593) larva L3 puffstage 3-6  (1020) larva L3 puffstage 7-9  (1185) white prepupae new  (1265) white prepupae 12hr  (1277) white prepupae 24hr  (1395) pupae 2d postWPP  (1451) pupae 3d postWPP  (1112) pupae 4d postWPP  (981) adult male 01day  (1109) adult male 05day  (1363) adult male 30day  (1194) adult female 01day  (1470) adult female 05day  (1929) adult female 30day  (2022) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3394) embryo 02-04hr  (5274) embryo 04-06hr  (4434) embryo 06-08hr  (3562) embryo 08-10hr  (2933) embryo 10-12hr  2412 embryo 12-14hr  1963 embryo 14-16hr  2339 embryo 16-18hr  1733 embryo 18-20hr    1269 embryo 20-22hr  1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP  1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day  1470 adult female 05day  1929 adult female 30day  2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3394 embryo 02-04hr    5274 embryo 04-06hr    4434 embryo 06-08hr    3562 embryo 08-10hr    2933 embryo 10-12hr    2412 embryo 12-14hr    1963 embryo 14-16hr    2339 embryo 16-18hr    1733 embryo 18-20hr    1269 embryo 20-22hr    1422 embryo 22-24hr    1203 larva L1    766 larva L2    790 larva L3 12hr old    582 larva L3 puffstage 1-2    593 larva L3 puffstage 3-6    1020 larva L3 puffstage 7-9    1185 white prepupae new    1265 white prepupae 12hr    1277 white prepupae 24hr    1395 pupae 2d postWPP    1451 pupae 3d postWPP    1112 pupae 4d postWPP    981 adult male 01day    1109 adult male 05day    1363 adult male 30day    1194 adult female 01day    1470 adult female 05day    1929 adult female 30day    2022 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0067864    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0067864 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0067864 expression level Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0067864 expression level Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    118.05 Larval Midgut no informative data Larval Hindgut    122 Larval Malpighian Tubules    142.8 Larval Fat Body    91.5 Larval Salivary Gland    277.6 Larval Trachea    106.875 Larval Carcass    148.075 Adult Head    126.5 Adult Eye    268.75 Adult Brain    137.2 Adult Thoracic-Abdominal Ganglion    133.3 Adult Crop    143.2 Adult Midgut    108.4 Adult Hindgut    134.4 Adult Malpighian Tubules    88.8 Adult Fat Body no informative data Adult Salivary Gland    167.6 Adult Heart    64.1 Adult VirginFemale Spermatheca    40.6 Adult InseminatedFemale Spermatheca    50.2 Adult Ovary    155 Adult Testis    99.1 Adult Male Accessory Gland    252.5 Adult Carcass    82.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    126.5   NA  Eye    268.75   NA  Brain    137.2   118.05  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    133.3   NA  Crop    143.2   no informative data  Midgut    108.4   122  Hindgut    134.4   142.8  Malpighian Tubules    88.8   91.5  Fat Body    no informative data   277.6  Salivary Gland    167.6   NA  Heart    64.1   106.875  Trachea    NA   NA  VirginFemale Spermatheca    40.6   NA  InseminatedFemale Spermatheca    50.2   NA  Ovary    155   NA  Testis    99.1   NA  Male Accessory Gland    252.5   148.075  Carcass    82.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0067864 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12021-RB FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Patj Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage, with Scer\GAL4hs.PB PatjScer\UAS.cBa lethal | pupal stage, with Scer\GAL4Act5C.PU PatjdsRNA.Scer\UAS.WIZ viable, with Scer\GAL4pnr-MD237 PatjGD7462 Other Phenotypes Allele wild-type Patj+tCOSMY1-1 Patj+tCOSMY8-1 Phenotype manifest in Allele ectoderm, with Scer\GAL4hs.PB PatjScer\UAS.cBa
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Patj Class Mutagen Stocks Known lesion Patjdre1 0 Yes
Alleles Carried on Transgenic Constructs ( 16 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Patj Class Mutagen Stocks Known lesion PatjGD7462 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PatjHMS01489 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PatjJF02051 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PatjKK110089 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Patj+tCOSMY1-1 in vitro construct - genomic fragment 0 Yes Patj+tCOSMY8-1 in vitro construct - genomic fragment 0 Yes PatjdsRNA.3'.cBa in vitro construct - RNAi 0 Yes PatjdsRNA.5'.cBa in vitro construct - RNAi 0 Yes PatjdsRNA.ORF.cBa in vitro construct - RNAi 0 Yes PatjdsRNA.Scer\UAS.WIZ in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes PatjEHHS in vitro construct - genomic fragment 0 Yes PatjEΔHS in vitro construct - deletion 0 Yes PatjScer\UAS.cBa in vitro construct - regulatory fusion 0 Yes PatjSHS in vitro construct - genomic fragment 0 Yes PatjSΔHS in vitro construct - deletion 0 Yes Patjt9.5 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6088 (Ryder, 2004.4.26) Df(3L)MY10 (Nam and Choi, 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7462} NA P{KK110089} NA P{TRiP.HMS01489} NA P{TRiP.JF02051} NA P{UAS-Patj.RNAi.WIZ} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 23 unique terms )
Terms Based on Experimental Evidence ( 12 terms )
Molecular Function
CV term Evidence References
protein kinase C binding inferred from physical interaction with aPKC (Sotillos et al., 2004)
Biological Process
CV term Evidence References
adherens junction organization inferred from mutant phenotype (Nam and Choi, 2006) establishment of planar polarity inferred from mutant phenotype (Djiane et al., 2005) NOT establishment or maintenance of neuroblast polarity inferred from mutant phenotype (Hong et al., 2001) establishment or maintenance of polarity of follicular epithelium inferred from physical interaction with crb (Tanentzapf et al., 2000) morphogenesis of follicular epithelium inferred from mutant phenotype (Tanentzapf et al., 2000) photoreceptor cell maintenance inferred from mutant phenotype (Nam and Choi, 2006) photoreceptor cell morphogenesis inferred from mutant phenotype (Nam and Choi, 2006)
Cellular Component
CV term Evidence References
apical plasma membrane inferred from direct assay (Tanentzapf et al., 2000) apicolateral plasma membrane inferred from direct assay (Sotillos et al., 2004) microtubule associated complex inferred from direct assay (Hughes et al., 2008) colocalizes_with plasma membrane inferred from direct assay (Mavrakis et al., 2009)
Terms Based on Predictions or Assertions ( 13 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
apical protein localization traceable author statement (Cereijido et al., 2003) cell-cell junction assembly non-traceable author statement (Wedlich, 2002) establishment or maintenance of cell polarity non-traceable author statement (Smith, 2000.6.1, Humbert et al., 2003) establishment or maintenance of polarity of embryonic epithelium traceable author statement (Mazumdar and Mazumdar, 2002) morphogenesis of an epithelium traceable author statement (Cereijido et al., 2003) zonula adherens assembly non-traceable author statement (Tepass et al., 2001)
Cellular Component
CV term Evidence References
apical cortex non-traceable author statement (Hong et al., 2001) apical plasma membrane non-traceable author statement (Wedlich, 2002) cytoplasm non-traceable author statement (Smith, 2000.6.1) traceable author statement (Tanentzapf et al., 2000) nuclear envelope non-traceable author statement (Tanentzapf et al., 2000) plasma membrane non-traceable author statement (Bachmann et al., 2001) septate junction traceable author statement (Wedlich, 2002) subapical complex traceable author statement (Medina et al., 2002)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Patj allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68832 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0067864 DroID - A comprehensive database of gene and protein interactions. • FBgn0067864 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44100
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24839 Dere\GG14826 Dgri\GH16435 Dmoj\GI12519 Dper\GL25307 Dpse\GA11344 Dsim\GD13649 Dvir\GJ12423 Dwil\GK20329 Dyak\GE21190
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008400-PA Aedes aegypti (mosquito) AGAP007108-PA Anopheles gambiae (mosquito) 205386 Branchiostoma floridae (lancelet) BGIBMGA000812-PA Bombyx mori (silk worm) ENSBTAP00000029300 Bos taurus (bovine) ENSCAFP00000027768 Canis familiaris (dog) CPIJ018849 Culex pipens (mosquito) 21791 Daphnia pulex (daphnia) ENSGACP00000016467 Gymnopilus aculeatus (mushroom) 82368 Hypsipyla robusta (cedar shoot borer) ISCW019646-PA Ixodes scapularis (deer tick) ENSMODP00000024196 Monodelphis domestica (gray opossum) ENSORLP00000025377 Oryzias latipes (japanese killifish) PHUM000590-PA Pediculus humanus (human body louse) PP16863 Pristionchus pacificus (nematode) ENSPPYP00000001500 Pongo pygmaeus (orangutan) Smp_048980 Schistosoma mansoni (trematode parasite) XP_001193360.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001813830.1 Tribolium castaneum (red flour beetle) ENSTNIP00000007772 Tetraodon nigroviridis (green spotted pufferfish) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17877 LH11901 ISCW019646 FBgn0238465 FBgn0222326 FBgn0199665 FBgn0185357 FBgn0169372 JGI_V11_21791 FBgn0071398 FBgn0162891 FBgn0162890 FBgn0135276 FBgn0123906 FBgn0107081 FBgn0101832 CPIJ018849 BGIBMGA000812 ACYPI006710 GB10846 AGAP007108 AAEL017560 PHUM180840 GLEAN_10040 GLEAN_09801 GLEAN_01640
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	26282 y1 v1; P{TRiP.JF02051}attP2 35747 y1 sc* v1; P{TRiP.HMS01489}attP2
VDRC	v101877 P{KK110089}VIE-260B v31620 w1118; P{GD7462}v31620
Genomic Clones ( 1 )
	BACR10D15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 88 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD22238
Other clones	DPiM_LD22238
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH19768 GH21910 LD11115 LD16707 LD31202 LD37747 LD40067 LD44449 LD47557 LD47571 LP12223 LP13461 LP13558 LP16482 RE04474 RE05919 RE13905 RE16651 RE18930 RE24615 RE24759 RE28437 RE28482 RE30756 RE32055 RE37069 RE42172 RE55275 RE55743 RE69367 RE71447 RE74365 RH10245 RH10769 RH24524 RH29403 RH35125 RH67390 SD02421 SD05651 SD23121 SD26252
Other clones	106942 122640 148107 214473.19 280718 EK220519 EK244223 EK245758 EK253522 EK305561 EP11625 LD28508 RP001001414 RP001001466 RP001002634 RP001002668 RP001004186 RP001007090 RP001007734 RP001008403 RP001009906 RP001010788 RP001013491 RP001014459 RP001020113 RP001021805 RP001023690 RP001023878 RP001024738 RP001025458 RP001025722 RP001026373 RP001026620 RP001028844 RP001030097 RP001031945 RP001032884 RP001033139 RP001037510 RP001041133 RP001045348 RP001045413 RP001047213 RP001050744
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0067864 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44100
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Patj CG12021 (Bayraktaroglu, 2000.4.12)
Additional comments	The "dre1/dlt" complementation group corresponds to the CG32315 gene and not to CG12021. It was previously reported in FBrf0107610 that the relevant locus for the "dre1" (dlt) complementation group was CG12021, based on mapping and complementation data (shown in Figure 4. of FBrf0107610). However, it has recently been shown (FBrf0167484) that "dre1" is allelic to CG32315 rather than CG12021. Re-evaluation of the "dre1" mutation indicates that the chromosome carries a T516S amino acid change in CG12021 and a stop codon at position 865 in CG32315. Since the mutation in CG12021 is conservative, it may not underlie the loss of imaginal discs observed in "dre1" mutants, and instead, the "dre1" mutant phenotypes described in FBrf0107610 are likely due to the mutation in CG32315. This is also supported by the observation that the P{PatjEHHS} construct (Figure 4 of FBrf0107610) now fails to rescue the "dre1" mutation. In addition, the "dre1" mutation fails to complement an allele in CG32315 ("Van04276"), clearly implicating CG32315 as causing the lethality associated with "dre1". It remains possible that the "dre1" phenotypes shown in Figure 6 of FBrf0107610 may result from a combination of mutations in both genes. Overexpression of CG12021 causes a severe loss of epithelial polarity as shown in Figure 7. of FBrf0107610. FlyBase curator comment: the T516S amino acid change in CG12021 on the "dre1" chromosome is represented by the allele Patjdre1 and the stop codon at position 865 in CG32315 on the "dre1" chromosome is represented by the allele dltdre1. (Bhat et al., 2003) The dlt phenotype maps to the CG32315 annotation, not the CG12021 annotation, as was reported previously (FBrf0107610). (Klaembt, 2003.10.31)
Other Comments
	Df(3L)MY10 flies with rescue transgenes for Cdc37, α-Spec and dlt but not for Patj (Cdc37+t9.5, α-SpecUbi-p63E.PP and dltUbi-p63E.PP) have typical planar cell polarity defects in the eye, including misrotated ommatidia and R3/R3 symmetrical clusters. (Djiane et al., 2005) FlyBase curator comment: The gene corresponding to genome annotation CG12021 was named "dlt:discs lost" in FBrf0107610. Subsequently the "dlt" phenotype was shown to map not to CG12021, but to the gene corresponding to genome annotation CG32315. Consequently the "dlt:discs lost" name was moved to CG32315, and the name of the gene for CG12021 was changed to "Patj". See Klaembt, 2003.10.31, personal communication to FlyBase. (Bhat et al., 1999, ) Patj plays a crucial role in the polarisation of embryonic epithelia during cellular blastoderm formation. (Bhat et al., 1999) Identification: Two hybrid screen with the cytoplasmic portion of Nrx-IV as a bait. (Bhat et al., 1998) Mutations cause pupal lethality with third instar larvae devoid of imaginal discs. (Bhat et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057994 NM_134317 NM_167917 RefSeq (Proteins) • NP_477342 NP_599144 NP_728674 DDBJ / EMBL / GenBank • AA817118 AAD34781 AAD43031 AAF47573 AAF81829 AAG22224 AAN11498 AC005557 AF103942 AF132193 AF274350 AI455245 Entrez Gene - A searchable database of RefSeq genes. • 44100 UniProtKB/Swiss-Prot • Q9NB04
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • PDZ/DHR/GLGF (IPR001478) L27 (IPR004172)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68832 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0067864 DroID - A comprehensive database of gene and protein interactions. • FBgn0067864 DRSC - Results from RNAi screens. • FBgn0067864 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0067864 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12021-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0067864 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44100 InParanoid A subset of ortholog calls from InParanoid. • AAEL008400-PA Aedes aegypti (mosquito) AGAP007108-PA Anopheles gambiae (mosquito) 205386 Branchiostoma floridae (lancelet) BGIBMGA000812-PA Bombyx mori (silk worm) ENSBTAP00000029300 Bos taurus (bovine) ENSCAFP00000027768 Canis familiaris (dog) CPIJ018849 Culex pipens (mosquito) 21791 Daphnia pulex (daphnia) ENSGACP00000016467 Gymnopilus aculeatus (mushroom) 82368 Hypsipyla robusta (cedar shoot borer) ISCW019646-PA Ixodes scapularis (deer tick) ENSMODP00000024196 Monodelphis domestica (gray opossum) ENSORLP00000025377 Oryzias latipes (japanese killifish) PHUM000590-PA Pediculus humanus (human body louse) PP16863 Pristionchus pacificus (nematode) ENSPPYP00000001500 Pongo pygmaeus (orangutan) Smp_048980 Schistosoma mansoni (trematode parasite) XP_001193360.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001813830.1 Tribolium castaneum (red flour beetle) ENSTNIP00000007772 Tetraodon nigroviridis (green spotted pufferfish) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /cytoskel/patj1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44100 modMine - Data generated by the modENCODE project. • FBgn0067864 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17877 LH11901 ISCW019646 FBgn0238465 FBgn0222326 FBgn0199665 FBgn0185357 FBgn0169372 JGI_V11_21791 FBgn0071398 FBgn0162891 FBgn0162890 FBgn0135276 FBgn0123906 FBgn0107081 FBgn0101832 CPIJ018849 BGIBMGA000812 ACYPI006710 GB10846 AGAP007108 AAEL017560 PHUM180840 GLEAN_10040 GLEAN_09801 GLEAN_01640
Synonyms & Secondary IDs ( 22 )
Reported As
Symbol Synonym	BcDNA:LD22238   CG12021 (Bhat et al., 2003, Sierralta, 2000.4.28, Perkins et al., 2009.3.31, Keleman et al., 2009.8.5, Hughes et al., 2008, Ni et al., 2011.7.19) dlt (Roper and Brown, 2003, Stork et al., 2004, Hong et al., 2003, Nam and Choi, 2003, Sokol and Cooley, 2003, Thiery, 2003, Henrique and Schweisguth, 2003, Lecuit et al., 2002, Beronja and Tepass, 2002, Kowalczyk and Moses, 2002, Wodarz, 2000, Wang et al., 1994, Tepass, 2002, Tanentzapf et al., 2000, Speck et al., 2003, Sotillos et al., 2003, Pichaud and Desplan, 2002, Peifer and Tepass, 2000, Nelson, 2003, Muller, 2000, Mueller, 2002, Medina et al., 2003, Liu and Lengyel, 2000, Lemmers et al., 2002, Lee and Kolodziej, 2002, Lecuit and Wieschaus, 2001, Lecuit and Wieschaus, 2000, Kramer, 2000, Kolodziej and Lee, 2002, Knust, 2001, Knust, 2000, Knust and Bossinger, 2002, Knoblich, 2000, Klebes and Knust, 2000, Jan and Jan, 2000, Izaddoost et al., 2000, Hunter, 1999, Hong et al., 2003, Gumbiner, 2000, Fuss et al., 2001, Deng et al., 2003, Deng et al., 2002, Deng et al., 2001, Braga and Harwood, 2001, Bilder, 2001, Bilder and Perrimon, 2000, Bhat et al., 1999, Bellaiche et al., 2001, Andrew et al., 2000, Shulman and St. Johnston, 1999, Shulman and St. Johnston, 1999, Shulman and St. Johnston, 1999, Cereijido et al., 2003, Medina et al., 2002, Mazumdar and Mazumdar, 2002, Bachmann et al., 2001, Hong et al., 2001, Tepass et al., 2001, Tanentzapf et al., 2000, Smith, 2000.6.1, Wedlich, 2002, Bayraktaroglu, 2000.4.12, Bhat et al., 1999, Bhat, 1998.3.10, Bhat et al., 1998, ) Dlt (Roper and Brown, 2003, Medina et al., 2002, Strickland and Burgess, 2004, Wu et al., 2004, Bilder et al., 2003, Izaddoost et al., 2002, Yeaman et al., 1999, Bayraktar et al., 2006) DLT (Genova and Fehon, 2003, Lecuit, 2004, Mavrakis et al., 2009) dlt:discs lost (Bhat, 1998.11.2) D-Patj (Le Bivic, 2005) DPATJ (Richard et al., 2006, Richard and Knust, 2005, Bulgakova and Knust, 2007, Tountas and Fortini, 2007, Berger et al., 2007, Corrigall et al., 2007, Sokac and Wieschaus, 2008, Bachmann et al., 2008, Richard et al., 2009) dPatj (Schweisguth, 2005, Djiane et al., 2005, Denef et al., 2008, Fichelson et al., 2010) DPatj (Bulgakova et al., 2005, Bulgakova et al., 2006, D'Alterio et al., 2005, Mavrakis et al., 2009, Schlichting and Dahmann, 2008, Gervais and Casanova, 2010, Chen et al., 2009, Fernandez-Minan et al., 2008) Dpatj (Nam and Choi, 2006, Nam et al., 2007, Chen et al., 2010) dPATJ (Blankenship et al., 2007, Huang et al., 2009) Patj (Hutterer et al., 2004, Tepass and Harris, 2007, Pilot et al., 2006, Wiggin et al., 2005, Beronja et al., 2005, Schneider et al., 2006, Lecuyer et al., 2007, Szafranski and Goode, 2007, Grzeschik et al., 2007, Egger et al., 2007, Hughes et al., 2008, Bayraktar et al., 2006, Leibfried et al., 2008, Mirouse et al., 2009, Hamaratoglu et al., 2009, Schlichting and Dahmann, 2008, Morais-de-Sá et al., 2010, Chen et al., 2010, Fichelson et al., 2010, Murthy et al., 2010, Mourikis et al., 2010, Letizia et al., 2011) PATJ (Zhang et al., 2005, Lecuit, 2004, Margolis and Borg, 2005, Suzuki and Ohno, 2006, Laprise et al., 2006, Bulgakova et al., 2008, Walther and Pichaud, 2010) PatJ (Pilot et al., 2006, Wu et al., 2007, Wang et al., 2008, Wang et al., 2011, Yasugi et al., 2010) patj (Richardson and Pichaud, 2010) PaTJ (Lecuit, 2004) Patj/Dlt (Li et al., 2008)
Name Synonym	discs lost (Mueller and Bossinger, 2003, Rashbass and Skaer, 2000, Stork et al., 2004, Paul et al., 2003, Bauer et al., 2002, Bhat et al., 1999, Bhat et al., 1998, ) discslost (Humbert et al., 2003) Discs lost (Ma et al., 2003, Lecuit, 2004) Discs Lost (Margolis and Borg, 2005) Patj
Secondary FlyBase IDs
	FBgn0002177 FBgn0024246 FBgn0035274
References ( 163 )
Generate a list of	All references relating to this gene ( 163 )
List References by type	Research paper  ( 83 ) Supplementary material  ( 2 ) Review  ( 40 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 18 ) FlyBase analysis  ( 2 ) Conference report  ( 2 ) DNA/RNA sequence record  ( 2 ) Computer file  ( 1 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 12 )
	Letizia et al., 2011, J. Cell Sci. 124(2): 240--251 Regulated Crb accumulation controls apical constriction and invagination in Drosophila tracheal cells. [FBrf0212559] Wang et al., 2011, Dev. Biol. 350(2): 414--428 Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development. [FBrf0212909] Chen et al., 2010, PLoS ONE 5(3): e9480 Role of Spastin in Apical Domain Control along the Rhabdomere Elongation in Drosophila Photoreceptor. [FBrf0210148] Chen et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(36): 15810--15815 The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. [FBrf0211766] Fichelson et al., 2010, Development 137(5): 815--824 lethal giant larvae is required with the par genes for the early polarization of the Drosophila oocyte. [FBrf0209930] Gervais and Casanova, 2010, Curr. Biol. 20(4): 359--366 In Vivo Coupling of Cell Elongation and Lumen Formation in a Single Cell. [FBrf0210105] Morais-de-Sá et al., 2010, Cell 141(3): 509--523 aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. [FBrf0210663] Mourikis et al., 2010, BMC Dev. Biol. 10: 107 Modifiers of notch transcriptional activity identified by genome-wide RNAi. [FBrf0212287] Murthy et al., 2010, Development 137(16): 2773--2783 Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization. [FBrf0211434] Richardson and Pichaud, 2010, Development 137(4): 641--650 Crumbs is required to achieve proper organ size control during Drosophila head development. [FBrf0209872] Walther and Pichaud, 2010, Curr. Biol. 20(12): 1065--1074 Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling. [FBrf0211169] Yasugi et al., 2010, Development 137(19): 3193--3203 Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe. [FBrf0211765] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...