FlyBase Gene Report: Dmel\eca

P24 TRANSPORTERS -: p24 proteins are single-pass type-I membrane proteins which are components of the COPI and COPII coated vesicles that mediate intracellular trafficking between the ER and Golgi. Their function in trafficking is unclear; they may be involved in cargo selection, quality control or vesicle formation. (Adapted from FBrf0174396 and FBrf0219054).

Pathway (FlyBase)

Wnt Production -: The canonical Wnt signaling pathway can be regulated upstream by the regulation of biogenesis and secretion of Wnt ligand. Genes within this group are directly involved in or have been shown to regulate this process.

Protein Function (UniProtKB)

Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization.

(UniProt, Q9I7K5)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\eca or the JBrowse view of Dmel\eca for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.39

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

eca-RA

FBtr0082098

NM_176439

946

216

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

eca-PA

FBpp0081576

25.2

216

7.05

NP_788616

AAG22137

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9I7K5

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\eca using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Gene Ontology (15 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

cargo receptor activity

inferred from sequence model

(Carney and Bowen, 2004)

Biological Process (8 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

dorsal/ventral pattern formation

inferred from mutant phenotype

(assigned by UniProt )

(Bartoszewski et al., 2004)

endoplasmic reticulum to Golgi vesicle-mediated transport

inferred from mutant phenotype

(Port et al., 2011)

regulation of post-mating oviposition

inferred from mutant phenotype

(Saleem et al., 2012)

wing disc development

inferred from mutant phenotype

(Port et al., 2011)

Wnt protein secretion

inferred from mutant phenotype

(Port et al., 2011)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

endoplasmic reticulum to Golgi vesicle-mediated transport

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

Golgi organization

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

Golgi vesicle transport

inferred from sequence model

(Carney and Bowen, 2004)

intracellular protein transport

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (6 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

COPII-coated ER to Golgi transport vesicle

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

endoplasmic reticulum

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

endoplasmic reticulum-Golgi intermediate compartment

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

Golgi apparatus

inferred from biological aspect of ancestor with PANTHER:PTN000516376

(assigned by GO_Central )

(Gaudet et al., 2011)

integral component of membrane

inferred from sequence model

(Carney and Bowen, 2004)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

dorsal ectoderm

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

dorsal epidermis primordium

(Fisher et al., 2012)

salivary gland body primordium

Comment: reported as salivary gland primordium

(Fisher et al., 2012)

tracheal primordium

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

visceral muscle primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic proventriculus

(Fisher et al., 2012)

embryonic proventriculus inner layer

(Fisher et al., 2012)

embryonic proventriculus intermediate layer

(Fisher et al., 2012)

embryonic/larval fat body

(Fisher et al., 2012)

embryonic/larval salivary gland

(Fisher et al., 2012)

embryonic/larval salivary gland body

(Fisher et al., 2012)

embryonic/larval visceral muscle

(Fisher et al., 2012)

oogenesis stage S9 -- S10 & adult stage | female

follicle cell

(Boltz et al., 2007)

nurse cell

(Boltz et al., 2007)

oogenesis stage S7 -- S8 & adult stage | female

follicle cell | faint

(Boltz et al., 2007)

nurse cell | faint

(Boltz et al., 2007)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female

adult brain

(Saleem et al., 2012)

thoracico-abdominal ganglion

(Saleem et al., 2012)

adult fat body

(Saleem et al., 2012)

female accessory gland

(Saleem et al., 2012)

spermathecum

(Saleem et al., 2012)

egg chamber

(Saleem et al., 2012)

adult stage | male

adult fat body

(Saleem et al., 2012)

male accessory gland

(Saleem et al., 2012)

ejaculatory duct

(Saleem et al., 2012)

ejaculatory bulb

(Saleem et al., 2012)

seminal vesicle

(Saleem et al., 2012)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

In the adult brain, a subset of neurons labelled with eca protein co-express the peptidergic marker Scer\GAL4^dimm-929.

(Saleem et al., 2012)

Marker for

Subcellular Localization

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\eca in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\eca

View exonic expression by tissue for Dmel\eca

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0069242

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0069242

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG33104-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33104

Flygut - An atlas of the Drosophila adult midgut

FBgn0069242

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\eca

Stages(s) 1-3
Stages(s) 4-6
Stages(s) 7-8
Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of eca

Transgenic constructs containing regulatory region of eca

Deletions and Duplications ( 4 )

Disrupted in

Df(3R)by10

(Bartoszewski et al., 2004)

Df(3R)by62

(Bartoszewski et al., 2004)

Df(3R)GB104

(Bartoszewski et al., 2004, Luschnig et al., 2004)

Not disrupted in

Df(3R)by416

(Bartoszewski et al., 2004, Luschnig et al., 2004)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Act5C.PI

eca^KK109376

lethal | embryonic stage | germline clone | maternal effect | recessive

eca^3R-45-33

lethal | embryonic stage | germline clone | non-rescuable maternal effect | recessive

eca^3R-45-33

lethal | maternal effect

partially lethal - majority die | recessive

eca^3R-45-33

viable

eca^EY10570

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

eca^GD17660

viable, with Scer\GAL4^Act5C.PI

eca^KK109376

viable, with Scer\GAL4^tin.CΔ4

eca^GD17660

Sterility

Allele

female semi-sterile, with Scer\GAL4^Act5C.PI

eca^KK109376

female sterile (with Df(3R)GB104)

eca¹

female sterile | recessive

fertile

eca^EY10570

male semi-sterile, with Scer\GAL4^Act5C.PI, Scer\GAL80^ts.αTub84B

eca^KK109376

male semi-sterile | recessive

Other Phenotypes

Allele

behavior defective | recessive

eca^BG02188

short lived, with Scer\GAL4^Mef2.PR

eca^GD17660

visible | adult stage, with Scer\GAL4^en.PU

eca^dsRNA.UAS

Phenotype manifest in

Allele

embryonic/first instar larval cuticle | dorsal | germline clone

wing margin, with Scer\GAL4^en.PU

eca^dsRNA.UAS

wing margin, with Scer\GAL4^hh.PU

eca^KK109376

wing margin | somatic clone, with Scer\GAL4^Act5C.PI

eca^KK109376

wing vein | ectopic

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\TMED4

14 of 15

Yes

Hsap\TMED9

13 of 15

Yes

Hsap\TMED10

2 of 15

Hsap\RASA4

1 of 15

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (4)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Tmed4

13 of 15

Yes

Mmus\Tmed9

13 of 15

Yes

Mmus\Tmed11

8 of 15

Yes

Mmus\Tmed10

2 of 15

Rattus norvegicus (Norway rat) (4)

Rnor\Tmed4

12 of 13

Yes

Rnor\Tmed9

12 of 13

Yes

Rnor\Tmed11

8 of 13

Yes

Rnor\Tmed10

2 of 13

Xenopus tropicalis (Western clawed frog) (5)

Xtro\tmed4

8 of 12

Yes

Xtro\tmed9

7 of 12

Yes

Xtro\gp25l

1 of 12

Yes

Xtro\tmed10

1 of 12

Xtro\tmed10

1 of 12

Danio rerio (Zebrafish) (4)

Drer\tmed4

12 of 15

Yes

Drer\tmed9

10 of 15

Yes

Drer\si:ch211-255i20.3

6 of 15

Yes

Drer\tmed10

2 of 15

Caenorhabditis elegans (Nematode, roundworm) (4)

Cele\Y60A3A.9

14 of 15

Yes

Cele\T08D2.1

7 of 15

Yes

Cele\F47G9.1

2 of 15

Cele\fbxa-134

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (10)

Atha\AT1G14010

5 of 9

Yes

Atha\AT1G26690

5 of 9

Yes

Atha\AT1G69460

5 of 9

Yes

Atha\AT3G29070

5 of 9

Yes

4 of 9

4 of 9

4 of 9

4 of 9

4 of 9

2 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (5)

Scer\ERP1

14 of 15

Yes

Scer\ERP6

13 of 15

Yes

Scer\ERP5

10 of 15

Yes

Scer\ERV25

2 of 15

Scer\EMP24

1 of 15

Schizosaccharomyces pombe (Fission yeast) (2)

Spom\SPBC16E9.09c

12 of 12

Yes

Spom\erv25

2 of 12

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190EZE )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\eca

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA17284

Drosophila persimilis

Dper\GL12279

Drosophila willistoni

Dwil\GK12749

Drosophila virilis

Dvir\GJ23362

Drosophila mojavensis

Dmoj\GI10144

Drosophila grimshawi

Dgri\GH18190

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150AH9 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17018858

Glossina morsitans

Tsetse fly

Gmor\GMOY003544

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_04586

Mayetiola destructor

Hessian fly

Mdes\Mdes016133

Mayetiola destructor

Hessian fly

Mdes\Mdes015405

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL000410

Anopheles darlingi

American malaria mosquito

Adar\ADAC000304

Anopheles gambiae

Malaria mosquito

Agam\AGAP003553

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ007480

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0BPH )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA010959

Danaus plexippus

Monarch butterfly

Dple\DPOGS209235-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL003633

Apis florea

Little honeybee

Aflo\2675033572

Apis mellifera

Western honey bee

Amel\LOC412554

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP15761

Bombus terrestris

Buff-tailed bumblebee

Bter\15210770

Linepithema humile

Argentine ant

Lhum\LH20419

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:002051

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG008131

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_10947

Tribolium castaneum

Red flour beetle

Tcas\TC000379

Pediculus humanus

Human body louse

Phum\PHUM512840

Rhodnius prolixus

Kissing bug

Rpro\RPRC003076

Cimex lectularius

Bed bug

Clec\CLEC002419

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI010154

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_01121

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0CNL )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR014401

Ixodes scapularis

Black-legged tick

Isca\ISCW001001

Stegodyphus mimosarum

African social velvet spider

Smim\KFM70239.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur11g03370

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_92223

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0JDW )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Tmed4

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_018134gn

Ciona intestinalis

Vase tunicate

Cint\LOC104266116

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000026634

Gallus gallus

Domestic chicken

Ggal\LOC422906

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (8)

Gene Symbol

Score

Source

Alignment

8 of 10

bai

3 of 10

CG9308

1 of 10

CG31787

1 of 10

CHOp24

1 of 10

loj

1 of 10

opm

1 of 10

p24-1

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TMED4; transmembrane p24 trafficking protein 4

14 of 15

612038

TMED9; transmembrane p24 trafficking protein 9

13 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

eca - Rab23

anti tag coimmunoprecipitation, peptide massfingerprinting

(Çiçek et al., 2016)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

eca

(Bartoszewski et al., 2004)

enhanceable

eca

(Müller et al., 2005)

suppressible

eca

(Port et al., 2011)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

66336

DroID - A comprehensive database of gene and protein interactions.

FBgn0069242

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

41177

MIST (protein-protein) - An integrated Molecular Interaction Database

Pathways

Signaling Pathways (FlyBase)

Wnt Production -: The canonical Wnt signaling pathway can be regulated upstream by the regulation of biogenesis and secretion of Wnt ligand. Genes within this group are directly involved in or have been shown to regulate this process.

Metabolic Pathways

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-49

Cytogenetic map

85E4-85E4

Sequence location

3R:9,684,469..9,685,476 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

85E4-85E4

Limits computationally determined from genome sequence between P{EP}Crc^EP3006 and P{lacW}s2681

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

85E-85E

(Luschnig et al., 2004)

Experimentally Determined Recombination Data

Location

3-49

(FlyBase, 2016)

3-46.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Bloomington

76063

y¹ v¹; P{TRiP.HMS05875}attP2

17282

w¹¹¹⁸; P{EP}eca^EP469/TM3, Sb¹

20188

y¹ w^67c23; P{EPgy2}eca^EY10570

FlyORF

F003219

M{UAS-eca.ORF.3xHA.GW}ZH-86Fb

VDRC

v101388

P{KK109376}VIE-260B

v49749

w¹¹¹⁸; P{GD17660}v49749

v49750

w¹¹¹⁸; P{GD17660}v49750

Genomic Clones (10)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (259)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0069242

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0069242

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

41177

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Saleem et al., 2012)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: CG33104 eca

(Bartoszewski et al., 2004)

Additional comments

Annotation CG9443 split into CG33104, CG33105 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 32 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

41177

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9I7K5

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0069242

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0069242

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33104

Flygut - An atlas of the Drosophila adult midgut

FBgn0069242

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

41177

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC000379

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG33104

modMine - A data warehouse for the modENCODE project

FBgn0069242

Linkouts

BioGRID - A database of protein and genetic interactions.

66336

DroID - A comprehensive database of gene and protein interactions.

FBgn0069242

DRSC - Results frm RNAi screens

FBgn0069242

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0069242

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG33104-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0069242

FlyMine - An integrated database for Drosophila genomics

FBgn0069242

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

41177

MIST (protein-protein) - An integrated Molecular Interaction Database

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG33104

(Kolkhof et al., 2017, Çiçek et al., 2016, Hosono et al., 2015, Chen et al., 2012, Zhang et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009, Stuart et al., 2007, Carney and Bowen, 2004)

CG9443

(Carney and Taylor, 2003)

ECA

(Saleem et al., 2012)

Eca

(Pastor-Cantizano et al., 2016, Li et al., 2015)

eca

(Rohde et al., 2017, Japanese National Institute of Genetics, 2012.5.21, Kondylis et al., 2011, Port et al., 2011, Tan et al., 2009, Boltz and Carney, 2008, Carney et al., 2008, Boltz et al., 2007)

p24

(Boltz et al., 2007)

Name Synonyms

Eclair

(Li et al., 2015, Tan et al., 2009)

eclair

(Pastor-Cantizano et al., 2016, Port et al., 2011, Ayroles et al., 2009, Edwards et al., 2009, Boltz and Carney, 2008, Carney et al., 2008, Boltz et al., 2007, Luschnig et al., 2004, Luschnig et al., 2004)

Secondary FlyBase IDs

FBgn0037732
FBgn0053104

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Study focus (0)

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References (48)

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