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Gene Dmel\Neb-cGP

General Information
Symbol	Dmel\Neb-cGP	Species	D. melanogaster
Name	Neb-cGP	Annotation symbol	CG15304
Feature type	protein_coding_gene	FlyBase ID	FBgn0083167
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	pncr006:X
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	9C4-9C5	Sequence location	X:10,354,769..10,355,911 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Neb-cGP is referred to in FlyBase by the symbol Dmel\Neb-cGP (CG15304, FBgn0083167). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: hormone activity. It is reported to be involved in the biological process: regulation of growth. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DAPIT. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1640624_s_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Neb-cGP. Gene sequence location is X:10354769..10355911.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 9C4-9C5   Limits computationally determined from genome sequence between P{EP}l(1)G0289EP379 and P{EP}PPP4R2rEP307
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Neb-cGP for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Neb-cGP-RA FBtr0071449  NM_144291   410   48 Neb-cGP-RB FBtr0332952  NM_001272479   987   48
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Neb-cGP-PA   FBpp0071384   5.1   48   10.76     NP_652548   AAF46590 Neb-cGP-PB   FBpp0305168   5.1   48   10.76     NP_001259408   AGB95251
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • DAPIT (IPR009125)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46590   AE014298 AGB95251   AY071289 AAL48911   AY071736 AAL49358   AY232128   BI235771   BI574730   BI584626   BI585896   BI612959   BI615643   BI616967   BP541142   BP542569   BP546201   CO177653   CO182946   CO190620   CO286723   CO310144   CO316921   CO331408   CO338814   CZ484857   EC058042   EC069493   EC200319   EC205118   EC215363   EC226940   EC262599   EV574873   EV575107   EV576440   EV579424   EV582813   EV584414   EV585780   EV586112   EV588814   EV591093   EV592546   EV593042
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W2U8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   anterior endoderm anlage   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1143.25 Larval Midgut    1748.6 Larval Hindgut    2554.8 Larval Malpighian Tubules    1313.7 Larval Fat Body    529 Larval Salivary Gland    1977 Larval Trachea    1212.075 Larval Carcass    2262.55 Adult Head    1948.9 Adult Eye    1919.05 Adult Brain    1440.6 Adult Thoracic-Abdominal Ganglion    1960.3 Adult Crop    1581.1 Adult Midgut    1704.1 Adult Hindgut    2681.9 Adult Malpighian Tubules    1513.3 Adult Fat Body    2208.4 Adult Salivary Gland    3192.6 Adult Heart    2375.6 Adult VirginFemale Spermatheca    1553.2 Adult InseminatedFemale Spermatheca    1406.3 Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland    1177.7 Adult Carcass    3214 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1143.25) Larval Midgut  (1748.6) Larval Hindgut  (2554.8) Larval Malpighian Tubules  (1313.7) Larval Fat Body  529 Larval Salivary Gland  (1977) Larval Trachea  (1212.075) Larval Carcass  (2262.55) Adult Head  (1948.9) Adult Eye  (1919.05) Adult Brain  (1440.6) Adult Thoracic-Abdominal Ganglion  (1960.3) Adult Crop  (1581.1) Adult Midgut  (1704.1) Adult Hindgut  (2681.9) Adult Malpighian Tubules  (1513.3) Adult Fat Body  (2208.4) Adult Salivary Gland  (3192.6) Adult Heart  (2375.6) Adult VirginFemale Spermatheca  (1553.2) Adult InseminatedFemale Spermatheca  (1406.3) Adult Ovary  (884.1) Adult Testis    396.4 Adult Male Accessory Gland  (1177.7) Adult Carcass  (3214) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1143.25) Larval Midgut  (1748.6) Larval Hindgut  (2554.8) Larval Malpighian Tubules  (1313.7) Larval Fat Body    529 Larval Salivary Gland  (1977) Larval Trachea  (1212.075) Larval Carcass  (2262.55) Adult Head  (1948.9) Adult Eye  (1919.05) Adult Brain  (1440.6) Adult Thoracic-Abdominal Ganglion  (1960.3) Adult Crop  (1581.1) Adult Midgut  (1704.1) Adult Hindgut  (2681.9) Adult Malpighian Tubules  (1513.3) Adult Fat Body  (2208.4) Adult Salivary Gland  (3192.6) Adult Heart  (2375.6) Adult VirginFemale Spermatheca  (1553.2) Adult InseminatedFemale Spermatheca  (1406.3) Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland  (1177.7) Adult Carcass  (3214) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1143.25 Larval Midgut    1748.6 Larval Hindgut    2554.8 Larval Malpighian Tubules    1313.7 Larval Fat Body    529 Larval Salivary Gland    1977 Larval Trachea    1212.075 Larval Carcass    2262.55 Adult Head    1948.9 Adult Eye    1919.05 Adult Brain    1440.6 Adult Thoracic-Abdominal Ganglion    1960.3 Adult Crop    1581.1 Adult Midgut    1704.1 Adult Hindgut    2681.9 Adult Malpighian Tubules    1513.3 Adult Fat Body    2208.4 Adult Salivary Gland    3192.6 Adult Heart    2375.6 Adult VirginFemale Spermatheca    1553.2 Adult InseminatedFemale Spermatheca    1406.3 Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland    1177.7 Adult Carcass    3214 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1143.25 Larval Midgut    1748.6 Larval Hindgut    2554.8 Larval Malpighian Tubules    1313.7 Larval Fat Body    529 Larval Salivary Gland    1977 Larval Trachea    1212.075 Larval Carcass    2262.55 Adult Head    1948.9 Adult Eye    1919.05 Adult Brain    1440.6 Adult Thoracic-Abdominal Ganglion    1960.3 Adult Crop    1581.1 Adult Midgut    1704.1 Adult Hindgut    2681.9 Adult Malpighian Tubules    1513.3 Adult Fat Body    2208.4 Adult Salivary Gland    3192.6 Adult Heart    2375.6 Adult VirginFemale Spermatheca    1553.2 Adult InseminatedFemale Spermatheca    1406.3 Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland    1177.7 Adult Carcass    3214 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1143.25) Larval Midgut  (1748.6) Larval Hindgut  (2554.8) Larval Malpighian Tubules  (1313.7) Larval Fat Body  529 Larval Salivary Gland  (1977) Larval Trachea  (1212.075) Larval Carcass  (2262.55) Adult Head  (1948.9) Adult Eye  (1919.05) Adult Brain  (1440.6) Adult Thoracic-Abdominal Ganglion  (1960.3) Adult Crop  (1581.1) Adult Midgut  (1704.1) Adult Hindgut  (2681.9) Adult Malpighian Tubules  (1513.3) Adult Fat Body  (2208.4) Adult Salivary Gland  (3192.6) Adult Heart  (2375.6) Adult VirginFemale Spermatheca  (1553.2) Adult InseminatedFemale Spermatheca  (1406.3) Adult Ovary  (884.1) Adult Testis    396.4 Adult Male Accessory Gland  (1177.7) Adult Carcass  (3214) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1143.25 Larval Midgut  (1748.6) Larval Hindgut  (2554.8) Larval Malpighian Tubules  1313.7 Larval Fat Body    529 Larval Salivary Gland  (1977) Larval Trachea  1212.075 Larval Carcass  (2262.55) Adult Head  (1948.9) Adult Eye  (1919.05) Adult Brain  1440.6 Adult Thoracic-Abdominal Ganglion  (1960.3) Adult Crop  1581.1 Adult Midgut  1704.1 Adult Hindgut  (2681.9) Adult Malpighian Tubules  1513.3 Adult Fat Body  (2208.4) Adult Salivary Gland  (3192.6) Adult Heart  (2375.6) Adult VirginFemale Spermatheca  1553.2 Adult InseminatedFemale Spermatheca  1406.3 Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland  1177.7 Adult Carcass  (3214) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1143.25 Larval Midgut    1748.6 Larval Hindgut    2554.8 Larval Malpighian Tubules    1313.7 Larval Fat Body    529 Larval Salivary Gland    1977 Larval Trachea    1212.075 Larval Carcass    2262.55 Adult Head    1948.9 Adult Eye    1919.05 Adult Brain    1440.6 Adult Thoracic-Abdominal Ganglion    1960.3 Adult Crop    1581.1 Adult Midgut    1704.1 Adult Hindgut    2681.9 Adult Malpighian Tubules    1513.3 Adult Fat Body    2208.4 Adult Salivary Gland    3192.6 Adult Heart    2375.6 Adult VirginFemale Spermatheca    1553.2 Adult InseminatedFemale Spermatheca    1406.3 Adult Ovary    884.1 Adult Testis    396.4 Adult Male Accessory Gland    1177.7 Adult Carcass    3214 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1948.9   NA  Eye    1919.05   NA  Brain    1440.6   1143.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1960.3   NA  Crop    1581.1   1748.6  Midgut    1704.1   2554.8  Hindgut    2681.9   1313.7  Malpighian Tubules    1513.3   529  Fat Body    2208.4   1977  Salivary Gland    3192.6   NA  Heart    2375.6   1212.075  Trachea    NA   NA  VirginFemale Spermatheca    1553.2   NA  InseminatedFemale Spermatheca    1406.3   NA  Ovary    884.1   NA  Testis    396.4   NA  Male Accessory Gland    1177.7   2262.55  Carcass    3214 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult    132 carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (27) central nervous system, larvae L3  (27) central nervous system, pupae P8  26 head, virgin 1-day female  (49) head, virgin 4-day female  (30) head, virgin 20-day female  26 head, mated 1-day female  (46) head, mated 4-day female  (29) head, mated 20-day female  (30) head, mated 1-day male  (56) head, mated 4-day male  (44) head, mated 20-day male  (45) salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult  (54) digestive system, 4-day adult  (37) digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8  (34) carcass, larvae L3 wandering    21 carcass, 1-day adult  (132) carcass, 4-day adult  (63) carcass, 20-day adult  (43) ovary, virgin 4-day female  (29) ovary, mated 4-day female    17 testis, mated 4-day male  (29) accessory gland, mated 4-day male  (27) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult  (132) carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult    132 carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult    132 carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  27 central nervous system, larvae L3  27 central nervous system, pupae P8  26 head, virgin 1-day female  (49) head, virgin 4-day female  30 head, virgin 20-day female  26 head, mated 1-day female  (46) head, mated 4-day female  29 head, mated 20-day female  30 head, mated 1-day male  (56) head, mated 4-day male  (44) head, mated 20-day male  (45) salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult  (54) digestive system, 4-day adult  (37) digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8  (34) carcass, larvae L3 wandering    21 carcass, 1-day adult  (132) carcass, 4-day adult  (63) carcass, 20-day adult  (43) ovary, virgin 4-day female  29 ovary, mated 4-day female    17 testis, mated 4-day male  29 accessory gland, mated 4-day male  27 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult  132 carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    27 central nervous system, larvae L3    27 central nervous system, pupae P8    26 head, virgin 1-day female    49 head, virgin 4-day female    30 head, virgin 20-day female    26 head, mated 1-day female    46 head, mated 4-day female    29 head, mated 20-day female    30 head, mated 1-day male    56 head, mated 4-day male    44 head, mated 20-day male    45 salivary gland, larvae L3 wandering    7 salivary gland, white prepupae    8 digestive system, larvae L3 wandering    20 digestive system, 1-day adult    54 digestive system, 4-day adult    37 digestive system, 20-day adult    24 fat body, larvae L3 wandering    13 fat body, white prepupae    10 fat body, pupae P8    34 carcass, larvae L3 wandering    21 carcass, 1-day adult    132 carcass, 4-day adult    63 carcass, 20-day adult    43 ovary, virgin 4-day female    29 ovary, mated 4-day female    17 testis, mated 4-day male    29 accessory gland, mated 4-day male    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr    112 embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr    112 embryo 18-20hr    140 embryo 20-22hr    193 embryo 22-24hr    162 larva L1    195 larva L2    213 larva L3 12hr old    235 larva L3 puffstage 1-2    120 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP    220 pupae 4d postWPP    312 adult male 01day    300 adult male 05day    233 adult male 30day    97 adult female 01day    234 adult female 05day    116 adult female 30day    97 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (71) embryo 02-04hr  (95) embryo 04-06hr  (88) embryo 06-08hr  (85) embryo 08-10hr  (74) embryo 10-12hr  (112) embryo 12-14hr  (70) embryo 14-16hr  (73) embryo 16-18hr  (112) embryo 18-20hr  (140) embryo 20-22hr  (193) embryo 22-24hr  (162) larva L1  (195) larva L2  (213) larva L3 12hr old  (235) larva L3 puffstage 1-2  (120) larva L3 puffstage 3-6  (62) larva L3 puffstage 7-9  (44) white prepupae new  (38) white prepupae 12hr  (36) white prepupae 24hr  (42) pupae 2d postWPP  (87) pupae 3d postWPP  (220) pupae 4d postWPP  (312) adult male 01day  (300) adult male 05day  (233) adult male 30day  (97) adult female 01day  (234) adult female 05day  (116) adult female 30day  (97) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr  (112) embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr  (112) embryo 18-20hr  (140) embryo 20-22hr  (193) embryo 22-24hr  (162) larva L1  (195) larva L2  (213) larva L3 12hr old  (235) larva L3 puffstage 1-2  (120) larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP  (220) pupae 4d postWPP  (312) adult male 01day  (300) adult male 05day  (233) adult male 30day    97 adult female 01day  (234) adult female 05day  (116) adult female 30day    97 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr    112 embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr    112 embryo 18-20hr    140 embryo 20-22hr    193 embryo 22-24hr    162 larva L1    195 larva L2    213 larva L3 12hr old    235 larva L3 puffstage 1-2    120 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP    220 pupae 4d postWPP    312 adult male 01day    300 adult male 05day    233 adult male 30day    97 adult female 01day    234 adult female 05day    116 adult female 30day    97 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr    112 embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr    112 embryo 18-20hr    140 embryo 20-22hr    193 embryo 22-24hr    162 larva L1    195 larva L2    213 larva L3 12hr old    235 larva L3 puffstage 1-2    120 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP    220 pupae 4d postWPP    312 adult male 01day    300 adult male 05day    233 adult male 30day    97 adult female 01day    234 adult female 05day    116 adult female 30day    97 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (71) embryo 02-04hr  (95) embryo 04-06hr  (88) embryo 06-08hr  (85) embryo 08-10hr  (74) embryo 10-12hr  (112) embryo 12-14hr  (70) embryo 14-16hr  (73) embryo 16-18hr  (112) embryo 18-20hr  (140) embryo 20-22hr  (193) embryo 22-24hr  (162) larva L1  (195) larva L2  (213) larva L3 12hr old  (235) larva L3 puffstage 1-2  (120) larva L3 puffstage 3-6  (62) larva L3 puffstage 7-9  (44) white prepupae new  (38) white prepupae 12hr  (36) white prepupae 24hr  (42) pupae 2d postWPP  (87) pupae 3d postWPP  (220) pupae 4d postWPP  (312) adult male 01day  (300) adult male 05day  (233) adult male 30day  (97) adult female 01day  (234) adult female 05day  (116) adult female 30day  (97) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr  112 embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr  112 embryo 18-20hr  140 embryo 20-22hr  (193) embryo 22-24hr  (162) larva L1  (195) larva L2  (213) larva L3 12hr old  (235) larva L3 puffstage 1-2  120 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP  (220) pupae 4d postWPP  (312) adult male 01day  (300) adult male 05day  (233) adult male 30day    97 adult female 01day  (234) adult female 05day  116 adult female 30day    97 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    71 embryo 02-04hr    95 embryo 04-06hr    88 embryo 06-08hr    85 embryo 08-10hr    74 embryo 10-12hr    112 embryo 12-14hr    70 embryo 14-16hr    73 embryo 16-18hr    112 embryo 18-20hr    140 embryo 20-22hr    193 embryo 22-24hr    162 larva L1    195 larva L2    213 larva L3 12hr old    235 larva L3 puffstage 1-2    120 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    44 white prepupae new    38 white prepupae 12hr    36 white prepupae 24hr    42 pupae 2d postWPP    87 pupae 3d postWPP    220 pupae 4d postWPP    312 adult male 01day    300 adult male 05day    233 adult male 30day    97 adult female 01day    234 adult female 05day    116 adult female 30day    97 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    145 Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11    121 antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (145) Schneider line 2 Sg4  (75) embryonic 1182-4H  (30) embryonic GM2  (28) embryonic Kc167  (42) embryonic S1  (44) embryonic S3  (48) leg disc CME L1  (52) wing disc CME-W2  (61) wing disc ML-DmD8  (60) wing disc ML-DmD9  (83) wing disc ML-DmD16-c3  (35) wing disc ML-DmD21  (99) wing disc ML-DmD32  (68) haltere disc ML-DmD17-c3  (43) eye-antennal disc ML-DmD11  (121) antennal disc ML-DmD20-c5  (45) mixed discs ML-DmD4-c1  (50) CNS ML-DmBG1-c1  (68) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2  (46) ovary fGS/OSS    10 ovary OSC  (42) ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (145) Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11  (121) antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    145 Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11    121 antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    145 Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11    121 antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (145) Schneider line 2 Sg4  (75) embryonic 1182-4H  30 embryonic GM2  28 embryonic Kc167  (42) embryonic S1  (44) embryonic S3  (48) leg disc CME L1  (52) wing disc CME-W2  (61) wing disc ML-DmD8  (60) wing disc ML-DmD9  (83) wing disc ML-DmD16-c3  (35) wing disc ML-DmD21  (99) wing disc ML-DmD32  (68) haltere disc ML-DmD17-c3  (43) eye-antennal disc ML-DmD11  (121) antennal disc ML-DmD20-c5  (45) mixed discs ML-DmD4-c1  (50) CNS ML-DmBG1-c1  (68) CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2  (46) ovary fGS/OSS    10 ovary OSC  (42) ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (145) Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11  121 antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    145 Schneider line 2 Sg4    75 embryonic 1182-4H    30 embryonic GM2    28 embryonic Kc167    42 embryonic S1    44 embryonic S3    48 leg disc CME L1    52 wing disc CME-W2    61 wing disc ML-DmD8    60 wing disc ML-DmD9    83 wing disc ML-DmD16-c3    35 wing disc ML-DmD21    99 wing disc ML-DmD32    68 haltere disc ML-DmD17-c3    43 eye-antennal disc ML-DmD11    121 antennal disc ML-DmD20-c5    45 mixed discs ML-DmD4-c1    50 CNS ML-DmBG1-c1    68 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    46 ovary fGS/OSS    10 ovary OSC    42 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    123 Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3    134 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult  (76) Cadmium 50 mM 6 hrs, larvae L3  (123) Cadmium 50 mM 12 hrs, larvae L3  (57) Cadmium 50 mM 48 hrs, 4-day adult  (66) Cadmium 100 mM 48 hrs, 4-day adult  (31) Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3  (53) Ethanol 5% 3 hrs, larvae L3  (95) Ethanol 10% 3 hrs, larvae L3  (94) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (69) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  (57) Paraquat 10 mM 48 hrs, 4-day adult  (54) Rotenone 2 μg 12 hrs, larvae L3  (99) Rotenone 8 μg 12 hrs, larvae L3  (134) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3  (123) Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3  (134) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    123 Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3    134 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    123 Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3    134 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult  (76) Cadmium 50 mM 6 hrs, larvae L3  (123) Cadmium 50 mM 12 hrs, larvae L3  (57) Cadmium 50 mM 48 hrs, 4-day adult  (66) Cadmium 100 mM 48 hrs, 4-day adult  31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3  (53) Ethanol 5% 3 hrs, larvae L3  (95) Ethanol 10% 3 hrs, larvae L3  (94) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (69) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  (57) Paraquat 10 mM 48 hrs, 4-day adult  (54) Rotenone 2 μg 12 hrs, larvae L3  (99) Rotenone 8 μg 12 hrs, larvae L3  (134) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3  123 Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3  134 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    13 heat shock, 4-day adult    76 Cadmium 50 mM 6 hrs, larvae L3    123 Cadmium 50 mM 12 hrs, larvae L3    57 Cadmium 50 mM 48 hrs, 4-day adult    66 Cadmium 100 mM 48 hrs, 4-day adult    31 Copper 0.5 mM 12 hrs, larvae L3    25 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    23 Zinc 4.5 mM 48 hrs, 4-day adult    23 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    95 Ethanol 10% 3 hrs, larvae L3    94 Caffeine 1.5 mg/ml 4 hrs, larvae L3    69 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    57 Paraquat 10 mM 48 hrs, 4-day adult    54 Rotenone 2 μg 12 hrs, larvae L3    99 Rotenone 8 μg 12 hrs, larvae L3    134 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_15 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • RH45340 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0083167 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15304-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Neb-cGP Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Neb-cGPGD4006 Neb-cGPGD16212 viable Neb-cGPf02352 Sterility Allele fertile Neb-cGPf02352 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Neb-cGP Class Mutagen Stocks Known lesion Neb-cGPf02352 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Neb-cGP Class Mutagen Stocks Known lesion Neb-cGPGD16212 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Neb-cGPGD4006 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Neb-cGPKK112160 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4006} NA P{GD16212} NA P{KK112160} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}Neb-cGPf02352 NA insertion of mobile activating element P{GSV1}C76C76 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
hormone activity traceable author statement (de Loof, 2008)
Biological Process
CV term Evidence References
regulation of growth traceable author statement (de Loof, 2008)
Cellular Component
CV term Evidence References
extracellular space traceable author statement (de Loof, 2008)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Neb-cGP - CG8745 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Neb-cGP - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Neb-cGP - icln experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Neb-cGP allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0083167
Orthologs
OrthoDB Orthologs (32) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6SJ61R Dipteran inclusive ortholog search EOG60GD1N Insect inclusive ortholog search EOG6BK427 Arthropod inclusive ortholog search EOG6X0K9S Metazoa inclusive ortholog search EOG63VBRZ
Orthologs in Drosophila Species (EOG6SJ61R)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Neb-cGP     Drosophila simulans   Dsim\GD24782 Y   Drosophila erecta   Dere\GG18357 Y   Drosophila yakuba   Dyak\GE17844 Y   Drosophila ananassae   Dana\GF19337 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13636 Y   Drosophila persimilis   Dper\GL14971 Y   Drosophila willistoni   Dwil\GK19768 Y   Drosophila virilis   Dvir\GJ14804 Y   Drosophila mojavensis   Dmoj\GI15198 Y   Drosophila grimshawi   Dgri\GH12017 Y
Orthologs in non-Drosophila Dipterans (EOG60GD1N)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013913   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005292   Anopheles gambiae Malaria mosquito  Agam\AGAP004790   Anopheles gambiae Malaria mosquito  Agam\AGAP004788   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004394
Orthologs in non-Dipteran Insects (EOG6BK427)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003685 Y Atta cephalotes Leafcutter ant  Acep\ACEP12523 Y Linepithema humile Argentine ant  Lhum\LH21506 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14360 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI066058 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI53781 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007684 Y Tribolium castaneum Red flour beetle  Tcas\Neb-cGP Y
Orthologs in non-Insect Arthropods (EOG6X0K9S)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Golga4 Y Ixodes scapularis Deer tick  Isca\ISCW022131 Y
Orthologs in non-Arthropod Metazoa (EOG63VBRZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024800gn Y Danio rerio Zebrafish  Drer\si:dkeyp-80c12.10 Y Mus musculus House mouse  Mmus\Usmg5 Y Rattus norvegicus Norway rat  Rnor\LOC100362685 Y Rattus norvegicus Norway rat  Rnor\Usmg5 Y Homo sapiens Human  Hsap\USMG5 Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\USMG5
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24782 Drosophila erecta Dere\GG18357 Drosophila yakuba Dyak\GE17844 Drosophila ananassae Dana\GF19337 Drosophila pseudoobscura pseudoobscura Dpse\GA13636 Drosophila persimilis Dper\GL14971 Drosophila willistoni Dwil\GK19768 Drosophila virilis Dvir\GJ14804 Drosophila mojavensis Dmoj\GI15198 Drosophila grimshawi Dgri\GH12017
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	18544 w1118 PBac{WH}Neb-cGPf02352
Harvard	- PBac{WH}Neb-cGPf02352
VDRC	v107937 P{KK112160}VIE-260B v11317 w1118 P{GD4006}v11317 v47846 w1118 P{GD16212}v47846
Genomic Clones ( 2 )
	BACR29G02 BACR48E06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 36 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE31692 RH45340
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RH23873 RH25591 RH26554 RH41984 RH47154
Other clones	59223 161935 162745 272802 300502 CK01.60C.E6 Dmel_dig_004364_0647_1574 Dmel_dig_005764_0648_2880 Dmel_dig_006294_0628_1914 Dmel_dig_007146_0602_1212 Dmel_dig_009686_0586_1698 Dmel_dig_011977_0604_0953 Dmel_dig_014491_0683_0504 Dmel_dig_014566_0654_3305 Dmel_neb_001363_0649_3659 Dmel_neb_006608_0075_2667 Dmel_neb_007811_0618_2166 Dmel_neb_011353_0445_3469 EC24325 EK048851 EK054005 EK063651 EK220603 EK266210 EK299631 EN17654 FGA011A03 FGC014E08 FGH103H06
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0083167 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50417
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Neb-cGP CG15304 (Tupy, 2005.4.22)
Source for database merge of	Source for merge of: CG15304 BcDNA:RE31692 (FlyBase, 1996-) Source for merge of: CG15304 BcDNA:RH45340 (FlyBase, 1996-)
Additional comments	Source for merge of CG15304 BcDNA:RE31692 was TrEMBL update (date:020807). (FlyBase, 1996-) Source for merge of CG15304 BcDNA:RH45340 was TrEMBL update (date:020807). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_144291 NM_001272479 RefSeq (Proteins) • NP_652548 NP_001259408 DDBJ / EMBL / GenBank • AAF46590 AAL48911 AAL49358 AGB95251 AY071289 AY071736 BI235771 BI615643 CZ484857 Entrez Gene - A searchable database of RefSeq genes. • 50417 UniProtKB/TrEMBL • Q9W2U8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • DAPIT (IPR009125) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH45340
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0083167 DRSC - Results from RNAi screens. • FBgn0083167 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0083167 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15304-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0083167 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 50417 modMine - Data generated by the modENCODE project. • FBgn0083167
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	BcDNA:RE31692   BcDNA:RH45340   CG15304 (Tupy, 2005.4.22, Blanchette et al., 2004, De Loof et al., 2001, FlyBase, 1996-, Molnar et al., 2006, Keleman et al., 2009.8.5, Tomancak et al., 2007, Cammarato et al., 2011) Neb-cGP (de Loof, 2008, Malone et al., 2012) pncr006:X (Tupy et al., 2005, Tupy et al., 2005)
Name Synonym	Neb-cGP (Cammarato et al., 2011) putative noncoding RNA 006:X (Tupy et al., 2005)
Secondary FlyBase IDs
	FBgn0040943 FBgn0047010 FBgn0047119
References ( 24 )
Generate a list of	All references relating to this gene ( 24 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 5 ) Review  ( 2 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 3 ) Website  ( 1 )
Recent research papers ( 1 )
	Malone et al., 2012, Genome Biol. 13(4): r28 Mediation of Drosophila autosomal dosage effects and compensation by network interactions. [FBrf0219684] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...