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Gene Dmel\CG34317

General Information
Symbol	Dmel\CG34317	Species	D. melanogaster
Name		Annotation symbol	CG34317
Feature type	protein_coding_gene	FlyBase ID	FBgn0085346
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	99D3-99D3	Sequence location	3R:25,882,581..25,883,853 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG34317 (FBgn0085346). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: ribonuclease activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: tRNA processing. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribonuclease P/MRP protein subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, during early larval stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1629388_s_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG34317 expression signal. See the GBrowse view of CG34317 to determine the overlapping gene(s). Gene sequence location is 3R:25882581..25883853.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 99D3-99D3
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG34317 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG34317-RA FBtr0112516  NM_001104507   1168   111
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG34317-PA   FBpp0111428   12.5   111   5.70     NP_001097977   ABW08806
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ribonuclease P/MRP protein subunit (IPR002759)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142042   AA142043   AA142095   AA142096   AE014297 ABW08806   AI108124   AI108197   BE976163   BG634693   BI352491   BI564456   BT003292   CO153027   CO271185   CO319001   CO322507   EC076720   EC197577   EC238982   EC238983   EC246465   EC261761   GH750683   GH752956   GH754156   GH755406   GH756485   GH757545   GH760959   GH776171   GH777239   GH789971   GH794148   GH795549   GH796594   GH805382   GH811623   GH817640   GH817937   GH824440   GH827548   GH834164   GH845639   GH851194   GH851578   GH851588   GH856112   GH858961   GH864626   GH865621   GH866409   GH871110   GH875891   GH876927   GH878167   GH879804   GH882325   GH894833   GH900915   GH901777   GH906655   GH912530   GH916064   GH917748   GH918472   GH923576   GH931928   GH943905   GH944572   GH948896   GH950114   GH950163   GH953724   GH957552   GH965077   GH966144   GH966427   GH969783   GH970552   GH975636   GH979979   GH982437   GH982586
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A8JRG8
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    209.65 Larval Midgut    98 Larval Hindgut    105.8 Larval Malpighian Tubules    61.9 Larval Fat Body    88.2 Larval Salivary Gland    126 Larval Trachea    123.75 Larval Carcass    100.35 Adult Head    109.3 Adult Eye    90.25 Adult Brain    166.6 Adult Thoracic-Abdominal Ganglion    185.4 Adult Crop    113.3 Adult Midgut    130.3 Adult Hindgut    134.9 Adult Malpighian Tubules    176 Adult Fat Body    124.7 Adult Salivary Gland    95.8 Adult Heart    145.95 Adult VirginFemale Spermatheca    115.9 Adult InseminatedFemale Spermatheca    129.4 Adult Ovary    246.3 Adult Testis    91 Adult Male Accessory Gland    155.2 Adult Carcass    125.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    109.3   NA  Eye    90.25   NA  Brain    166.6   209.65  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    185.4   NA  Crop    113.3   98  Midgut    130.3   105.8  Hindgut    134.9   61.9  Malpighian Tubules    176   no informative data  Fat Body    124.7   126  Salivary Gland    95.8   NA  Heart    145.95   123.75  Trachea    NA   NA  VirginFemale Spermatheca    115.9   NA  InseminatedFemale Spermatheca    129.4   NA  Ovary    246.3   NA  Testis    91   NA  Male Accessory Gland    155.2   100.35  Carcass    125.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (32) central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female  (36) ovary, mated 4-day female  (28) testis, mated 4-day male  (32) accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female  (36) ovary, mated 4-day female  28 testis, mated 4-day male  32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    32 central nervous system, larvae L3    15 central nervous system, pupae P8    15 head, virgin 1-day female    10 head, virgin 4-day female    9 head, virgin 20-day female    8 head, mated 1-day female    6 head, mated 4-day female    15 head, mated 20-day female    10 head, mated 1-day male    10 head, mated 4-day male    17 head, mated 20-day male    21 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    11 digestive system, 4-day adult    17 digestive system, 20-day adult    11 fat body, larvae L3 wandering    3 fat body, white prepupae    5 fat body, pupae P8    13 carcass, larvae L3 wandering    10 carcass, 1-day adult    8 carcass, 4-day adult    13 carcass, 20-day adult    10 ovary, virgin 4-day female    36 ovary, mated 4-day female    28 testis, mated 4-day male    32 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, during early larval stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (29) embryo 02-04hr    13 embryo 04-06hr  (30) embryo 06-08hr  (37) embryo 08-10hr  (38) embryo 10-12hr  (54) embryo 12-14hr  (36) embryo 14-16hr  (37) embryo 16-18hr  (29) embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1  (58) larva L2  (50) larva L3 12hr old  (29) larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP  (27) pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day  (33) adult female 05day  (39) adult female 30day  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  29 embryo 02-04hr    13 embryo 04-06hr  30 embryo 06-08hr  (37) embryo 08-10hr  (38) embryo 10-12hr  (54) embryo 12-14hr  (36) embryo 14-16hr  (37) embryo 16-18hr  29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1  (58) larva L2  (50) larva L3 12hr old  29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP  27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day  (33) adult female 05day  (39) adult female 30day  (39) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    13 embryo 04-06hr    30 embryo 06-08hr    37 embryo 08-10hr    38 embryo 10-12hr    54 embryo 12-14hr    36 embryo 14-16hr    37 embryo 16-18hr    29 embryo 18-20hr    20 embryo 20-22hr    23 embryo 22-24hr    21 larva L1    58 larva L2    50 larva L3 12hr old    29 larva L3 puffstage 1-2    12 larva L3 puffstage 3-6    13 larva L3 puffstage 7-9    13 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    18 pupae 2d postWPP    27 pupae 3d postWPP    23 pupae 4d postWPP    15 adult male 01day    18 adult male 05day    19 adult male 30day    21 adult female 01day    33 adult female 05day    39 adult female 30day    39 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (91) Schneider line 2 Sg4  (83) embryonic 1182-4H  (33) embryonic GM2  (33) embryonic Kc167  (72) embryonic S1  (44) embryonic S3  (42) leg disc CME L1  (45) wing disc CME-W2  (66) wing disc ML-DmD8  (46) wing disc ML-DmD9  (40) wing disc ML-DmD16-c3  (37) wing disc ML-DmD21  (57) wing disc ML-DmD32    24 haltere disc ML-DmD17-c3  (33) eye-antennal disc ML-DmD11  (57) antennal disc ML-DmD20-c5  (49) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (54) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (40) ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (91) Schneider line 2 Sg4  (83) embryonic 1182-4H  (33) embryonic GM2  (33) embryonic Kc167  (72) embryonic S1  (44) embryonic S3  (42) leg disc CME L1  (45) wing disc CME-W2  (66) wing disc ML-DmD8  (46) wing disc ML-DmD9  (40) wing disc ML-DmD16-c3  (37) wing disc ML-DmD21  (57) wing disc ML-DmD32    24 haltere disc ML-DmD17-c3  (33) eye-antennal disc ML-DmD11  (57) antennal disc ML-DmD20-c5  (49) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (54) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (40) ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    91 Schneider line 2 Sg4    83 embryonic 1182-4H    33 embryonic GM2    33 embryonic Kc167    72 embryonic S1    44 embryonic S3    42 leg disc CME L1    45 wing disc CME-W2    66 wing disc ML-DmD8    46 wing disc ML-DmD9    40 wing disc ML-DmD16-c3    37 wing disc ML-DmD21    57 wing disc ML-DmD32    24 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    57 antennal disc ML-DmD20-c5    49 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    54 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    40 ovary fGS/OSS    25 ovary OSC    24 ovary OSS    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult  (29) Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3  (29) Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult  (27) Paraquat 10 mM 48 hrs, 4-day adult  (33) Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult  29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3  29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult  27 Paraquat 10 mM 48 hrs, 4-day adult  (33) Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    10 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    14 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    22 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    9 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    9 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    21 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    12 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    33 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG34317 Class Mutagen Stocks Known lesion CG34317e02275 2 Yes
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG34317 Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG7950e02275 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data on: 2008-03-20)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
ribonuclease activity inferred from electronic annotation with InterPro:IPR002759 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
tRNA processing inferred from electronic annotation with InterPro:IPR002759 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_dicistronic_mRNA (FlyBase Genome Annotators, 2007) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG34317 - Rpp30 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG34317 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0085346
Orthologs
OrthoDB Orthologs (26) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QVCZP Dipteran inclusive ortholog search EOG63BMZD Insect inclusive ortholog search EOG63FFV6 Arthropod inclusive ortholog search EOG6Q2BZV Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6QVCZP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG15526     Drosophila melanogaster fruit fly  Dmel\CG34317     Drosophila simulans   Dsim\GD21502   Y Drosophila simulans   Dsim\GD21501   Y Drosophila sechellia   Dsec\GM12859   Y Drosophila sechellia   Dsec\GM12860   Y Drosophila erecta   Dere\GG11731   Y Drosophila yakuba   Dyak\GE10857   Y Drosophila yakuba   Dyak\GE10856   Y Drosophila ananassae   Dana\GF18821   Y Drosophila ananassae   Dana\GF18820   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA26936   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA13784   Y Drosophila persimilis   Dper\GL14027   Y Drosophila persimilis   Dper\GL14026   Y Drosophila willistoni   Dwil\GK13870   Y Drosophila virilis   Dvir\GJ10781   Y Drosophila mojavensis   Dmoj\GI24211   Y
Orthologs in non-Drosophila Dipterans (EOG63BMZD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001089 Y Anopheles gambiae Malaria mosquito  Agam\AGAP013417 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015132 Y
Orthologs in non-Dipteran Insects (EOG63FFV6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB44530 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL11244 Y Linepithema humile Argentine ant  Lhum\LH23061 Y Pediculus humanus Human body louse  Phum\PHUM546530 Y
Orthologs in non-Insect Arthropods (EOG6Q2BZV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\H3 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	18033 w1118; PBac{RB}CG7950e02275 CG34317e02275/TM6B, Tb1
Harvard	- PBac{RB}CG7950e02275
Genomic Clones ( 2 )
	BACR05L15 BACR07A18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 79 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM02245
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH06869 GH06969 GM19513 RH61736
Other clones	62527 108247 174621 521980 AT30993 bs47f06 CK01.167B.A6 CK00164 CK00231 EK102227 EK188255 EK275744 EN01126 RP003003219 RP003035968 RP003061730 RP003073579 RP003090534 RP003095737 RP003107735 RP003116789 RP003124143 RP003158215 RP003172017 RP003186908 RP003188530 RP003193951 RP003195374 RP003205797 RP003207393 RP003210736 RP003211690 RP003221154 RP003241153 RP003246527 RP003267277 RP003267556 RP003274084 RP003275731 RP003280947 RP003322410 RP003339721 RP003340901 RP003342488 RP003350277 RP003368786 RP003376036 RP003404863 RP003429788 RP003435774 RP003473035 RP003483489 RP003537892 RP003559583 RP003573265 RP003609233 RP003619390 RP003627731 RP004056293 RP004124865 RP004176090 RP004177033 RP004192959 RP004219430 RP004221338 RP004239842 RP004245594 RP004245619 RP004337852 RP004425245 RP004436715 RP004480078 RP004482658 RP004496775
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0085346 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740224
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG7950 (CG7950) and CG34317 (CG34317). (FlyBase Genome Annotators, 2007)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001104507 RefSeq (Proteins) • NP_001097977 DDBJ / EMBL / GenBank • ABW08806 Entrez Gene - A searchable database of RefSeq genes. • 5740224 UniProtKB/TrEMBL • A8JRG8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ribonuclease P/MRP protein subunit (IPR002759)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0085346 DRSC - Results from RNAi screens. • FBgn0085346 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0085346 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740224 modMine - Data generated by the modENCODE project. • FBgn0085346
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG34317 (FlyBase Genome Annotators, 2007, Jungreis, 2011.11.18, ) Dromel_CG7950_FBtr0085563_CHCHD4inmorf_uORF (Hayden and Bosco, 2008)
Name Synonym
Secondary FlyBase IDs
	FBan0007950 FBgn0039745
References ( 9 )
Research paper	Hayden and Bosco, 2008, BMC Genomics 9: 61 Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. [FBrf0204849]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Hayden and Bosco, 2008, BMC Genomics: File 1: Conserved peptide uORF and associated mORF amino acid sequences in Drosophila melanogaster. [FBrf0205942]
Personal communication to FlyBase	Jungreis, 2011.11.18, Stop codon readthrough: excluded candidates. Stop codon readthrough: excluded candidates. [FBrf0216885] Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]