FB2020_06, released Dec 22, 2020

Gene: Dmel\CG34354

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General Information
Symbol
Dmel\CG34354
Species
D. melanogaster
Name
Annotation Symbol
CG34354
Feature Type
protein_coding_gene
FlyBase ID
FBgn0085383
Gene Model Status
Current
Stock Availability
8 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
98C1-98C1
Sequence location
3R:28,146,880..28,240,526 [+]
Recombination map

3-95

RefSeq locus
NT_033777 REGION:28146880..28240526
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (2 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables mRNA binding
inferred from sequence or structural similarity
(Lasko, 2000)
enables nucleic acid binding
inferred from electronic annotation with InterPro:IPR000504
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\CG34354 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Double stop-codon suppression (UAG, UGA) postulated; FBrf0222074, FlyBase analysis); supported by conservation of the extended ORF across Drosophila species (FBrf0202906).

Gene model reviewed during 5.53

gene_with_stop_codon_read_through ; SO:0000697

Gene model reviewed during 6.02

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Rodriguez et al., 2012)
gene_with_stop_codon_read_through
(FlyBase Genome Annotators, 2013)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
CG34354-RD
FBtr0304917
NM_001170284
3135
431
CG34354-RE
FBtr0304916
NM_001170285
4568
431
CG34354-RF
FBtr0344296
NM_001104483
3313
550
CG34354-RG
FBtr0346762
NM_001316621
3313
434
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
CG34354-PD
FBpp0293456
46.1
431
7.23
NP_001163755
ACZ95049
CG34354-PE
FBpp0293455
46.1
431
7.23
NP_001163756
ACZ95050
CG34354-PF
FBpp0310700
60.4
550
6.90
NP_001097953
ABW08789
CG34354-PG
FBpp0312357
46.3
434
7.23
NP_001303550
ALI30647
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

431 aa isoforms: CG34354-PD, CG34354-PE
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG34354 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\CG34354 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 10 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of CG34354
Transgenic constructs containing regulatory region of CG34354
Deletions and Duplications ( 0 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
lethal - all die during P-stage, with Scer\GAL4Mef2.PR
Other Phenotypes
Allele
some die during pupal stage, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (41)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\TIA1
7 of 15
Yes
No
Hsap\TIAL1
7 of 15
Yes
No
Hsap\BOLL
1 of 15
No
No
1  
Hsap\CIRBP
1 of 15
No
Yes
Hsap\CSTF2
1 of 15
No
No
Hsap\CSTF2T
1 of 15
No
No
Hsap\DAZL
1 of 15
No
No
1  
Hsap\EIF4B
1 of 15
No
No
Hsap\EIF4H
1 of 15
No
No
Hsap\HNRNPA0
1 of 15
No
No
Hsap\HNRNPA1
1 of 15
No
No
3  
Hsap\HNRNPA1L2
1 of 15
No
No
Hsap\HNRNPA2B1
1 of 15
No
No
4  
Hsap\HNRNPA3
1 of 15
No
No
Hsap\HNRNPAB
1 of 15
No
No
Hsap\HNRNPC
1 of 15
No
No
1  
Hsap\HNRNPCL2
1 of 15
No
No
Hsap\HNRNPCL3
1 of 15
No
No
Hsap\HNRNPCL4
1 of 15
No
No
Hsap\HNRNPD
1 of 15
No
No
Hsap\HNRNPDL
1 of 15
No
No
3  
Hsap\HNRNPM
1 of 15
No
No
Hsap\MYEF2
1 of 15
No
No
Hsap\RALY
1 of 15
No
No
Hsap\RALYL
1 of 15
No
No
Hsap\RAVER1
1 of 15
No
Yes
Hsap\RBM3
1 of 15
No
Yes
Hsap\RBM34
1 of 15
No
No
Hsap\SLIRP
1 of 15
No
No
Hsap\SNRNP35
1 of 15
No
No
Hsap\SNRNP70
1 of 15
No
No
Hsap\SRSF1
1 of 15
No
No
1  
Hsap\SRSF4
1 of 15
No
No
Hsap\SRSF6
1 of 15
No
No
1  
Hsap\SRSF9
1 of 15
No
No
1  
Hsap\SRSF10
1 of 15
No
No
Hsap\SRSF12
1 of 15
No
No
Hsap\TRA2A
1 of 15
No
No
1  
Hsap\TRA2B
1 of 15
No
No
Hsap\TRNAU1AP
1 of 15
No
No
Hsap\ZCRB1
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (42)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Tial1
7 of 15
Yes
No
Mmus\Tia1
6 of 15
No
No
Mmus\Boll
1 of 15
No
No
Mmus\Cirbp
1 of 15
No
Yes
Mmus\Cstf2
1 of 15
No
No
Mmus\Cstf2t
1 of 15
No
No
Mmus\Dazl
1 of 15
No
No
Mmus\Eif4b
1 of 15
No
No
Mmus\Eif4h
1 of 15
No
No
Mmus\Gm9833
1 of 15
No
No
Mmus\Gm12666
1 of 15
No
No
Mmus\Gm21379
1 of 15
No
No
Mmus\Hnrnpa0
1 of 15
No
No
Mmus\Hnrnpa1
1 of 15
No
No
Mmus\Hnrnpa2b1
1 of 15
No
No
Mmus\Hnrnpa3
1 of 15
No
No
Mmus\Hnrnpab
1 of 15
No
No
Mmus\Hnrnpc
1 of 15
No
No
Mmus\Hnrnpdl
1 of 15
No
No
Mmus\Hnrnpd
1 of 15
No
No
Mmus\Hnrnpm
1 of 15
No
No
Mmus\Larp7
1 of 15
No
No
Mmus\Myef2
1 of 15
No
No
Mmus\Ralyl
1 of 15
No
No
Mmus\Raly
1 of 15
No
No
Mmus\Rbm3
1 of 15
No
Yes
Mmus\Rbm31y
1 of 15
No
No
Mmus\Rbm34
1 of 15
No
No
Mmus\Slirp
1 of 15
No
No
Mmus\Snrnp35
1 of 15
No
No
Mmus\Snrnp70
1 of 15
No
No
Mmus\Srsf1
1 of 15
No
No
Mmus\Srsf4
1 of 15
No
No
Mmus\Srsf5
1 of 15
No
No
Mmus\Srsf6
1 of 15
No
No
Mmus\Srsf9
1 of 15
No
No
Mmus\Srsf10
1 of 15
No
No
Mmus\Srsf12
1 of 15
No
No
Mmus\Tra2a
1 of 15
No
No
Mmus\Tra2b
1 of 15
No
No
Mmus\Trnau1ap
1 of 15
No
No
Mmus\Zcrb1
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (38)
Rnor\Tial1
7 of 13
Yes
No
Rnor\Tia1
6 of 13
No
No
Rnor\Boll
1 of 13
No
No
Rnor\Cirbp
1 of 13
No
Yes
Rnor\Cstf2
1 of 13
No
No
Rnor\Cstf2t
1 of 13
No
No
Rnor\Dazl
1 of 13
No
No
Rnor\Eif4b
1 of 13
No
No
Rnor\Eif4h
1 of 13
No
No
Rnor\Hnrnpa1
1 of 13
No
No
Rnor\Hnrnpa2b1
1 of 13
No
No
Rnor\Hnrnpab
1 of 13
No
No
Rnor\Hnrnpc
1 of 13
No
No
Rnor\Hnrnpdl
1 of 13
No
No
Rnor\Hnrnpd
1 of 13
No
No
Rnor\Hnrnpm
1 of 13
No
No
Rnor\Larp7
1 of 13
No
No
Rnor\LOC681410
1 of 13
No
No
Rnor\LOC100911576
1 of 13
No
No
Rnor\LOC103689931
1 of 13
No
No
Rnor\Myef2
1 of 13
No
No
Rnor\Ralyl
1 of 13
No
No
Rnor\Raly
1 of 13
No
No
Rnor\Rbm3
1 of 13
No
Yes
Rnor\Rbm31y
1 of 13
No
No
Rnor\Rbm34
1 of 13
No
No
Rnor\Slirp
1 of 13
No
No
Rnor\Snrnp35
1 of 13
No
No
Rnor\Snrnp70
1 of 13
No
No
Rnor\Srsf1
1 of 13
No
No
Rnor\Srsf4
1 of 13
No
No
Rnor\Srsf5
1 of 13
No
No
Rnor\Srsf6
1 of 13
No
No
Rnor\Srsf9
1 of 13
No
No
Rnor\Srsf10
1 of 13
No
No
Rnor\Tra2a
1 of 13
No
No
Rnor\Tra2b
1 of 13
No
No
Rnor\Zcrb1
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (35)
Xtro\tia1
6 of 12
Yes
No
Xtro\tial1
2 of 12
No
Yes
Xtro\cirbp
1 of 12
No
Yes
Xtro\cstf2
1 of 12
No
No
Xtro\dazl
1 of 12
No
No
Xtro\eif4b
1 of 12
No
No
Xtro\eif4h
1 of 12
No
No
Xtro\hnrnpa0
1 of 12
No
No
Xtro\hnrnpa1
1 of 12
No
No
Xtro\hnrnpa2b1
1 of 12
No
No
Xtro\hnrnpa3
1 of 12
No
No
Xtro\hnrnpab
1 of 12
No
No
Xtro\hnrnpc
1 of 12
No
No
Xtro\hnrnpdl
1 of 12
No
No
Xtro\hnrnpd
1 of 12
No
No
Xtro\hnrnpm
1 of 12
No
No
Xtro\krt5.1
1 of 12
No
No
Xtro\larp7
1 of 12
No
No
Xtro\myef2
1 of 12
No
No
Xtro\ralyl
1 of 12
No
No
Xtro\raly
1 of 12
No
No
Xtro\raver1
1 of 12
No
Yes
Xtro\rbm34
1 of 12
No
No
Xtro\snrnp70
1 of 12
No
No
Xtro\srsf1
1 of 12
No
No
Xtro\srsf4
1 of 12
No
No
Xtro\srsf5
1 of 12
No
No
Xtro\srsf6
1 of 12
No
No
Xtro\srsf9
1 of 12
No
No
Xtro\srsf10
1 of 12
No
No
Xtro\srsf12
1 of 12
No
No
Xtro\tra2a
1 of 12
No
No
Xtro\tra2b
1 of 12
No
No
Xtro\trnau1ap
1 of 12
No
No
Xtro\zcrb1
1 of 12
No
Yes
Danio rerio (Zebrafish) (46)
Drer\tia1
7 of 15
Yes
No
Drer\tia1l
7 of 15
Yes
No
Drer\tial1
7 of 15
Yes
No
Drer\cirbpa
1 of 15
No
Yes
Drer\cirbpb
1 of 15
No
Yes
Drer\cstf2
1 of 15
No
No
Drer\dazl
1 of 15
No
No
Drer\eif4ba
1 of 15
No
No
Drer\eif4bb
1 of 15
No
No
Drer\eif4h
1 of 15
No
No
Drer\hnrnpa0a
1 of 15
No
No
Drer\hnrnpa0l
1 of 15
No
No
Drer\hnrnpa1b
1 of 15
No
No
Drer\hnrnpa3
1 of 15
No
No
Drer\hnrnpaba
1 of 15
No
No
Drer\hnrnpabb
1 of 15
No
No
Drer\hnrnpc
1 of 15
No
No
Drer\hnrnpd
1 of 15
No
No
Drer\hnrnpdl
1 of 15
No
No
Drer\hnrnpm
1 of 15
No
No
Drer\larp7
1 of 15
No
No
Drer\myef2
1 of 15
No
No
Drer\ncl
1 of 15
No
No
Drer\ncoa5
1 of 15
No
No
Drer\raly
1 of 15
No
No
Drer\ralyl
1 of 15
No
No
Drer\rbm14a
1 of 15
No
No
Drer\rbm34
1 of 15
No
No
Drer\slirp
1 of 15
No
No
Drer\snrnp35
1 of 15
No
No
Drer\snrnp70
1 of 15
No
No
Drer\srsf1a
1 of 15
No
No
Drer\srsf1b
1 of 15
No
No
Drer\srsf4
1 of 15
No
No
Drer\srsf5a
1 of 15
No
No
Drer\srsf5b
1 of 15
No
No
Drer\srsf6a
1 of 15
No
No
Drer\srsf6b
1 of 15
No
No
Drer\srsf9
1 of 15
No
No
Drer\srsf10a
1 of 15
No
No
Drer\tra2a
1 of 15
No
No
Drer\tra2b
1 of 15
No
No
Drer\trnau1apa
1 of 15
No
No
Drer\trnau1apb
1 of 15
No
No
Drer\zcrb1
1 of 15
No
Yes
Drer\zgc:55733
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (17)
Cele\tiar-2
7 of 15
Yes
No
Cele\tiar-1
6 of 15
No
No
Cele\tiar-3
5 of 15
No
Yes
Cele\daz-1
1 of 15
No
No
Cele\drr-2
1 of 15
No
No
Cele\H28G03.1
1 of 15
No
No
Cele\R06C1.4
1 of 15
No
No
Cele\rbm-3.1
1 of 15
No
No
Cele\rbm-3.2
1 of 15
No
No
Cele\rbm-34
1 of 15
No
No
Cele\rsp-1
1 of 15
No
No
Cele\rsp-2
1 of 15
No
No
Cele\rsp-5
1 of 15
No
No
Cele\slrp-1
1 of 15
No
No
Cele\T07F10.3
1 of 15
No
No
Cele\tdp-1
1 of 15
No
No
Cele\ZK616.61
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (9)
Atha\AT3G14100
5 of 9
Yes
No
Atha\UBP1A
5 of 9
Yes
No
Atha\UBP1B
5 of 9
Yes
No
Atha\AT2G21440
1 of 9
No
No
Atha\AT2G41060
1 of 9
No
Yes
Atha\AT3G09160
1 of 9
No
Yes
Atha\EIF3G1
1 of 9
No
No
Atha\EIF3G2
1 of 9
No
No
Atha\UBA2A
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (23)
Scer\PUB1
7 of 15
Yes
No
Scer\NAM8
2 of 15
No
No
Scer\NGR1
2 of 15
No
No
Scer\CWC2
1 of 15
No
No
Scer\GBP2
1 of 15
No
No
Scer\HRB1
1 of 15
No
No
Scer\LHP1
1 of 15
No
No
Scer\MRN1
1 of 15
No
Yes
Scer\MUD1
1 of 15
No
No
Scer\NAB3
1 of 15
No
No
Scer\NAB6
1 of 15
No
Yes
Scer\NOP6
1 of 15
No
Yes
Scer\NOP12
1 of 15
No
No
Scer\NPL3
1 of 15
No
No
Scer\PIN4
1 of 15
No
No
Scer\PTI1
1 of 15
No
No
Scer\RIE1
1 of 15
No
Yes
Scer\RNA15
1 of 15
No
No
Scer\RRT5
1 of 15
No
Yes
Scer\SNP1
1 of 15
No
No
Scer\TIF3
1 of 15
No
No
Scer\WHI3
1 of 15
No
No
Scer\WHI4
1 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (3)
Spom\csx1
1 of 12
Yes
No
Spom\SPBC23E6.01c
1 of 12
Yes
No
Spom\SPBC660.15
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190AT1 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Dsim\GD21365
Drosophila sechellia
Dsec\GM16372
Drosophila erecta
Dere\GG11590
Drosophila yakuba
Dyak\GE23778
Drosophila ananassae
Dana\GF18877
Drosophila persimilis
Dper\GL23650
Drosophila willistoni
Dwil\GK22643
Drosophila virilis
Dvir\GJ22770
Drosophila mojavensis
Dmoj\GI22767
Drosophila mojavensis
Dmoj\GI16519
Drosophila grimshawi
Dgri\GH17442
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG0915089W )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17020843
Glossina morsitans
Tsetse fly
Gmor\GMOY011734
Glossina morsitans
Tsetse fly
Gmor\GMOY001687
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00403
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00406
Mayetiola destructor
Hessian fly
Mdes\Mdes004930
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL009072
Anopheles darlingi
American malaria mosquito
Adar\ADAC005481
Anopheles gambiae
Malaria mosquito
Agam\AGAP005292
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ003621
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0D4P )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA001619
Bombyx mori
Silkmoth
Bmor\BGIBMGA004892
Danaus plexippus
Monarch butterfly
Dple\DPOGS200156-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS214717-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL009161
Apis florea
Little honeybee
Aflo\2468482324
Apis florea
Little honeybee
Aflo\2153264516
Apis mellifera
Western honey bee
Amel\Rox8
Apis mellifera
Western honey bee
Amel\GB42292
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP20737
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP25257
Bombus terrestris
Buff-tailed bumblebee
Bter\15216431
Bombus terrestris
Buff-tailed bumblebee
Bter\15205361
Linepithema humile
Argentine ant
Lhum\LH20418
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00107d
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0026cd
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005752
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011625
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11831
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_02488
Tribolium castaneum
Red flour beetle
Tcas\TC031489
Tribolium castaneum
Red flour beetle
Tcas\TC009608
Pediculus humanus
Human body louse
Phum\PHUM511750
Pediculus humanus
Human body louse
Phum\PHUM514840
Rhodnius prolixus
Kissing bug
Rpro\RPRC002783
Cimex lectularius
Bed bug
Clec\CLEC012826
Cimex lectularius
Bed bug
Clec\CLEC003530
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002888
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008980
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13228
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_17487
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0D2G )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR013215
Ixodes scapularis
Black-legged tick
Isca\ISCW016601
Stegodyphus mimosarum
African social velvet spider
Smim\KFM66227.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM83144.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur09g01770
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_20224
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0FH8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Tial1
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000002150
Gallus gallus
Domestic chicken
Ggal\TIAL1
Gallus gallus
Domestic chicken
Ggal\TIA1
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (44)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
Rox8
5 of 10
trv
4 of 10
CstF64
2 of 10
Hrb87F
2 of 10
Hrb98DE
2 of 10
Rb97D
2 of 10
Rbp4
2 of 10
Secp43
2 of 10
SLIRP1
2 of 10
SLIRP2
2 of 10
B52
1 of 10
bol
1 of 10
Caper
1 of 10
CG1316
1 of 10
CG2931
1 of 10
CG3335
1 of 10
CG4612
1 of 10
CG5213
1 of 10
CG7903
1 of 10
CG11726
1 of 10
CG12288
1 of 10
CG33278
1 of 10
CG34334
1 of 10
CG42458
1 of 10
eIF3g1
1 of 10
eIF3g2
1 of 10
eIF4B
1 of 10
eIF4H1
1 of 10
eIF4H2
1 of 10
elav
1 of 10
fne
1 of 10
Hrb27C
1 of 10
Larp7
1 of 10
msi
1 of 10
Rbp6
1 of 10
Rbp9
1 of 10
rump
1 of 10
SF2
1 of 10
snRNP-U1-70K
1 of 10
sqd
1 of 10
ssx
1 of 10
Sxl
1 of 10
Syp
1 of 10
tra2
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    TIA1; TIA1 cytotoxic granule associated RNA binding protein
    7 of 15
    603518
      TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1
      7 of 15
      603413
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Interactions Browser
          Summary of Genetic Interactions
          esyN Network Diagram
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          3R
          Recombination map

          3-95

          Cytogenetic map
          98C1-98C1
          Sequence location
          3R:28,146,880..28,240,526 [+]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          98C1-98C1
          Limits computationally determined from genome sequence between P{PZ}btzrL203 and P{PZ}l(3)0648706487
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          3-95

          (FlyBase, 2016)

          3-93.2

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (8)
          Genomic Clones (65)
          cDNA Clones (80)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
            RNAi and Array Information
            Linkouts
            DRSC - Results frm RNAi screens
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            Antibody Information
            Laboratory Generated Antibodies
             
            Commercially Available Antibodies
             
            Other Information
            Relationship to Other Genes
            Source for database identify of
            Source for database merge of

            Source for merge of: CG12425 CG12852 CG4787

            (FlyBase Genome Annotators, 2007)
            Additional comments

            Annotations CG12425, CG12852, and CG4787 merged as CG34354 in release 5.2 of the genome annotation.

            (FlyBase Genome Annotators, 2007)

            "CG12425" may correspond to "Scim37". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim37" near/in "CG12425".

            (Dobie and Karpen, 2001.4.18)
            Other Comments

            RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.

            (Boutros et al., 2004)
            Origin and Etymology
            Discoverer
            Etymology
            Identification
            External Crossreferences and Linkouts ( 36 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            Flygut - An atlas of the Drosophila adult midgut
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            modMine - A data warehouse for the modENCODE project
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            FLIGHT - Cell culture data for RNAi and other high-throughput technologies
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyMine - An integrated database for Drosophila genomics
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Synonyms and Secondary IDs (5)
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (39)