FlyBase Gene Report: Dmel\Fili

General Information

Symbol

Dmel\Fili

Species

D. melanogaster

Name

Fish-lips

Annotation Symbol

CG34368

Feature Type

protein_coding_gene

FlyBase ID

FBgn0085397

Gene Model Status

Current

Stock Availability

18 publicly available

Gene Summary

Fish-lips (Fili) encodes a leucine-rich repeat family transmembrane protein. It regulates autonomous and nonautonomous apoptosis caused by the dioxin receptor homolog encoded by ss. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

58A3-58A4

Sequence location

2R:21,872,030..21,946,259 [+]

Recombination map

2-97

RefSeq locus

NT_033778 REGION:21872030..21946259

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in regulation of apoptotic process

inferred from mutant phenotype

(Adachi-Yamada et al., 2005)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

is_active_in extracellular matrix

inferred from biological aspect of ancestor with PANTHER:PTN001224703

(GO Reference Genome Project, 2011-)

is_active_in extracellular space

inferred from biological aspect of ancestor with PANTHER:PTN001224703

(GO Reference Genome Project, 2011-)

located_in membrane

inferred from sequence model

(Adachi-Yamada et al., 2005)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Fili for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry A0A6M3Q7U5)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.48

Stop-codon suppression (UGA) postulated; FBrf0243886.

Gene model reviewed during 6.32

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Fili-RC

FBtr0112593

NM_001103932

4859

738

Fili-RD

FBtr0330338

NM_137775

4584

738

Fili-RE

FBtr0479817

NM_001382077

4859

789

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Fili-PC

FBpp0111505

82.4

738

6.45

FBpp0303370

82.4

738

6.45

FBpp0428150

88.1

789

6.70

QJC18731

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

738 aa isoforms: Fili-PC, Fili-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fili using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.45

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Fili in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Fili

View exonic expression by tissue for Dmel\Fili

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740472/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085397

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085397

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085397

Flygut - An atlas of the Drosophila adult midgut

FBgn0085397

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 20 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Fili

Transgenic constructs containing regulatory region of Fili

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2R)Exel7169

(Ryder, 2004.4.26)

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | female, with Scer\GAL4^pnr-MD237

Fili^GD2136

lethal | female, with Scer\GAL4^Tub.PU

Fili^GD2136

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

Fili^GD431

viable, with Scer\GAL4^pnr-MD237

viable (with Df(2R)BSC802)

Fili⁰⁷⁸³⁷

Other Phenotypes

Allele

abnormal neuroanatomy | adult stage

Fili^CRISPR

abnormal neuroanatomy | adult stage, with C15^p65AD, Scer\GAL4^Mz19-GAL4DBD

Fili^GD2136

abnormal neuroanatomy | adult stage, with Scer\GAL4^elav-C155

abnormal neuroanatomy | adult stage | cell non-autonomous | somatic clone

Fili^CRISPR

Phenotype manifest in

Allele

abdominal tergite 5 | female

Fili^f04573

abdominal tergite 6 | female

Fili^f04573

adult antennal lobe projection neuron VM5

Fili^CRISPR

adult antennal lobe projection neuron VM5, with Scer\GAL4^elav-C155

adult antennal lobe projection neuron VM5 | cell non-autonomous | somatic clone

Fili^CRISPR

adult olfactory receptor neuron Or19

Fili^CRISPR

adult olfactory receptor neuron Or47b

Fili^CRISPR

adult olfactory receptor neuron Or47b, with C15^p65AD, Scer\GAL4^Mz19-GAL4DBD

Fili^GD2136

adult olfactory receptor neuron Or47b | cell non-autonomous | somatic clone

Fili^CRISPR

wing disc | somatic clone

Fili^Δ102

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (71)

Hsap\LINGO1

5 of 14

Yes

Hsap\LINGO2

4 of 14

Yes

Hsap\LINGO4

4 of 14

Yes

Hsap\CPN2

3 of 14

Hsap\LINGO3

3 of 14

Yes

3 of 14

3 of 14

3 of 14

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Hsap\LRRTM1

2 of 14

Yes

Hsap\LRRTM3

2 of 14

Yes

Hsap\NYX

2 of 14

Yes

Hsap\RTN4RL1

2 of 14

Hsap\RTN4RL2

2 of 14

Hsap\TRIL

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\LRRC70

1 of 14

Hsap\LRRIQ1

1 of 14

Yes

Hsap\LRRN4

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (44)

Rnor\Lingo1

5 of 14

Yes

Rnor\Cpn2

3 of 14

Rnor\Lingo3

3 of 14

Yes

Rnor\Lingo4

3 of 14

Yes

3 of 14

3 of 14

3 of 14

2 of 14

Yes

Rnor\Igfals

2 of 14

Rnor\Lingo2

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Rnor\Tril

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Lrriq1

1 of 14

Yes

Rnor\Lrrn4

1 of 14

Yes

Rnor\LRRTM1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (47)

Mmus\Lingo1

5 of 14

Yes

Mmus\Lingo2

4 of 14

Yes

Mmus\Lingo3

3 of 14

Yes

Mmus\Lingo4

3 of 14

Yes

3 of 14

3 of 14

3 of 14

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Mmus\Tril

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (62)

Xtro\lingo1

3 of 13

Yes

Xtro\lrrn1-like

3 of 13

Yes

Xtro\lrrn1

3 of 13

Yes

Xtro\lrrn3

3 of 13

Yes

Xtro\chadl

2 of 13

Xtro\gp5

2 of 13

Yes

Xtro\igfals

2 of 13

Xtro\lingo2

2 of 13

Yes

Xtro\lingo3

2 of 13

Xtro\lrrc4b

2 of 13

Yes

Xtro\lrrc4

2 of 13

Yes

Xtro\lrrc15

2 of 13

Yes

Xtro\lrrtm1

2 of 13

Yes

Xtro\nyx

2 of 13

Yes

Xtro\pde6g

2 of 13

Xtro\rtn4rl2

2 of 13

Yes

Xtro\tlrs5

2 of 13

Xtro\tril

2 of 13

Yes

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\elfn2

1 of 13

Xtro\flrt3

1 of 13

Yes

Xtro\kpna6

1 of 13

Xtro\lgr5

1 of 13

Xtro\LOC101730277

1 of 13

Yes

Xtro\LOC116410887

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\lrrn4

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\slitrk3

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (58)

Drer\lingo1a

3 of 14

Yes

Drer\lingo4a

3 of 14

Yes

Drer\LOC100535105

3 of 14

Yes

Drer\lrrn1

3 of 14

Yes

Drer\si:ch211-180f4.1

3 of 14

Yes

Drer\igfals

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Drer\si:ch211-170a17.1

2 of 14

Drer\si:dkey-1j5.4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\lgr4

1 of 14

Drer\LOC100004523

1 of 14

Drer\LOC101882092

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\lrrtm4l1

1 of 14

Drer\lrrtm4l2

1 of 14

Yes

Drer\nrros

1 of 14

Drer\nyx

1 of 14

Drer\ppp1r42

1 of 14

Yes

Drer\rtn4rl2a

1 of 14

Drer\rtn4rl2b

1 of 14

Drer\si:dkey-182i3.11

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Drer\zgc:153913

1 of 14

Drer\zgc:172282

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (17)

Cele\lron-11

2 of 14

Yes

Cele\lron-15

2 of 14

Yes

Cele\tol-1

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (54)

Agam\AgaP_AGAP011227

10 of 12

Yes

Agam\AgaP_AGAP011229

10 of 12

Yes

3 of 12

3 of 12

3 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (3)

Atha\AT1G48540

1 of 13

Yes

Atha\AT3G15410

1 of 13

Yes

Atha\AT3G17920

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Fili. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (42)

trn

5 of 13

caps

4 of 13

CG7509

3 of 13

lbk

2 of 13

Toll-7

2 of 13

18w

1 of 13

atk

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Con

1 of 13

conv

1 of 13

dtr

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Lkr

1 of 13

Lrt

1 of 13

ltl

1 of 13

Pxn

1 of 13

rdo

1 of 13

sli

1 of 13

TkR86C

1 of 13

Toll-6

1 of 13

Tollo

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

LINGO1; leucine rich repeat and Ig domain containing 1

model of autosomal recessive intellectual developmental disorder 64

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

LINGO1; leucine rich repeat and Ig domain containing 1

5 of 14

609791

INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 64; MRT64

autosomal recessive intellectual developmental disorder 64

LINGO2; leucine rich repeat and Ig domain containing 2

4 of 14

609793

LINGO4; leucine rich repeat and Ig domain containing 4

4 of 14

609794

CPN2; carboxypeptidase N subunit 2

3 of 14

603104

LINGO3; leucine rich repeat and Ig domain containing 3

3 of 14

609792

LRRN1; leucine rich repeat neuronal 1

3 of 14

619623

LRRN2; leucine rich repeat neuronal 2

3 of 14

605492

LRRN3; leucine rich repeat neuronal 3

3 of 14

619748

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0085397

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Neurexins and neuroligins

Class of Gene

gene_with_stop_codon_read_through

(FlyBase Genome Annotators, 2020, FlyBase Genome Annotators, 2019-)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-97

Cytogenetic map

58A3-58A4

Sequence location

2R:21,872,030..21,946,259 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

58A3-58A4

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-97

(FlyBase, 2016)

2-103.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (18)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

23968

w¹¹¹⁸; Mi{ET1}Fili^MB02223

84164

y¹ v¹; M{WKO.5-G1}ZH-86Fb

28568

y¹ v¹; P{TRiP.HM05054}attP2

62815

w¹¹¹⁸; PBac{IT.GAL4}Fili^0378-G4

65674

w¹¹¹⁸; PBac{IT.GAL4}Fili^1354-G4

77624

w¹¹¹⁸; PBac{IT.GAL4}Fili^2035-G4

34189

y¹ w^*; Mi{MIC}Fili^MI01398

11547

11736

109637

v1701

v44532

w¹¹¹⁸ P{GD2136}v44532

More stocks available...

Genomic Clones (53)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (79)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

RE58108

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0085397

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0085397

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Xie et al., 2019)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Fili is a Leucine-Rich Repeat (LRR) family transmembrane protein.

(Adachi-Yamada et al., 2005)

Relationship to Other Genes

Source for database merge of

Source for merge of: Fili CG13487

(FlyBase Genome Annotators, 2007)

Additional comments

Annotations CG13487 and CG4054 merged as CG34368 in release 5.2 of the genome annotation.

(FlyBase Genome Annotators, 2007)

Nomenclature History

Source for database identify of

Source for identity of: Fili CG4054

(Adachi-Yamada et al., 2005)

Nomenclature comments

Etymology

The name fish-lips is derived from the observation that the expression pattern of Fili in the wing disc made a fish lips-like shape.

(Adachi-Yamada et al., 2005)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG13487

CG34368

(National Institute of Genetics Fly Stocks, 2022-, Perkins et al., 2009, FlyBase Genome Annotators, 2007)

CG4054

CT13464

(Hynes and Zhao, 2000)

CT32855

(Hynes and Zhao, 2000)

Fili

(Pignataro et al., 2024, Voutyraki et al., 2023, FlyBase Genome Annotators, 2020, Gupta and Stocker, 2020, Bali and Zinn, 2019, FlyBase Genome Annotators, 2019-, Meltzer et al., 2019, Clandinin and Owens, 2016-, Gene Disruption Project members, 2016-, Dembeck et al., 2015, Dobson et al., 2015, Duff et al., 2015, Ashwal-Fluss et al., 2014, Ozkan et al., 2013, Carreira et al., 2011, Jungreis, 2011.11.18)

fili

(Fischer et al., 2024, Xie et al., 2019)

Name Synonyms

CG13487

Fish-lips

(Adachi-Yamada et al., 2005, Adachi-Yamada et al., 2005)

Secondary FlyBase IDs

FBgn0034669
FBgn0034668

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 33 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

5740472

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

A0A6M3Q7U5

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

A0A6M3Q7U5

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

5740472/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085397

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085397

FlyMine - An integrated database for Drosophila genomics

FBgn0085397

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34368

MARRVEL_MODEL - MARRVEL (model organism gene)

5740472

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0085397

DroID - A comprehensive database of gene and protein interactions.

FBgn0085397

DRSC - Results frm RNAi screens

FBgn0085397

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085397

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0085397

Flygut - An atlas of the Drosophila adult midgut

FBgn0085397

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0085397

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC001975

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Neurexins and neuroligins

References (55)

The following external sites may use different assemblies or annotations than FlyBase.

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