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Gene Dmel\CG34371

General Information
Symbol	Dmel\CG34371	Species	D. melanogaster
Name		Annotation symbol	CG34371
Feature type	protein_coding_gene	FlyBase ID	FBgn0085400
Gene Model Status	Current	Stock availability	9 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	59D1-59D2	Sequence location	2R:19,050,535..19,091,494 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG34371 (FBgn0085400). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: CD80-like, immunoglobulin C2-set; Fibronectin, type III; Immunoglobulin V-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Gene sequence location is 2R:19050535..19091494.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 59D1-59D2
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG34371 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Stop-codon suppression (UGA) postulated; FBrf0216884 gene_with_stop_codon_read_through ; SO:0000697 Gene model reviewed during 5.44
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG34371-RA FBtr0112596  NM_137923   5758   1140 CG34371-RB FBtr0330239  NM_137921   5758   1174
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG34371-PA   FBpp0111508   122.6   1140   7.77     NP_611767   AAF46967 CG34371-PB   FBpp0303272   126.1   1174   7.64     NP_611765   AAF46965
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • CD80-like, immunoglobulin C2-set (IPR013162) Immunoglobulin-like domain (IPR007110) Fibronectin, type III (IPR003961) Immunoglobulin subtype (IPR003599) Immunoglobulin subtype 2 (IPR003598) Immunoglobulin-like fold (IPR013783) Immunoglobulin V-set (IPR013106)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF46965   AE013599 AAF46967   BI230933   BP556114   BP556115   BP556751   BT010225   BT071814   BT099587   CK604998   CK604999   CO177701   CO185927   CO189951   CO285420   CO295198   CO311420   CO323500   CO344704   EC057066   EC058181   EC062660   EC063170   EC064180   EC068723   EC087779   EC218230   EC240445   EC250065   EC256338   GH751652   GH754682   GH756956   GH757443   GH757690   GH758944   GH759665   GH759797   GH777033   GH780073   GH786849   GH789525   GH789894   GH794494   GH798058   GH799427   GH799972   GH801827   GH802916   GH803722   GH815911   GH818855   GH819850   GH821044   GH821654   GH828611   GH829702   GH832040   GH836095   GH836249   GH836558   GH837617   GH840747   GH840798   GH842402   GH844434   GH849142   GH850302   GH852866   GH854663   GH859081   GH860055   GH864305   GH865255   GH865291   GH865489   GH865515   GH867223   GH867541   GH868629   GH872156   GH872980   GH875623   GH879064   GH881909   GH882363   GH884251   GH887584   GH890785   GH897396   GH897923   GH900691   GH901782   GH904497   GH909029   GH910042   GH913353   GH914934   GH915909   GH917158   GH917729   GH917982   GH922177   GH922347   GH922886   GH923791   GH923875   GH924325   GH924529   GH930011   GH931637   GH934974
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W1T6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    15 central nervous system, larvae L3    21 central nervous system, pupae P8    25 head, virgin 1-day female    7 head, virgin 4-day female    6 head, virgin 20-day female    5 head, mated 1-day female    6 head, mated 4-day female    5 head, mated 20-day female    5 head, mated 1-day male    11 head, mated 4-day male    10 head, mated 20-day male    9 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    3 fat body, pupae P8    4 carcass, larvae L3 wandering    11 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    1 ovary, mated 4-day female    0 testis, mated 4-day male    4 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr  (29) embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr  29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    6 embryo 04-06hr    20 embryo 06-08hr    22 embryo 08-10hr    29 embryo 10-12hr    24 embryo 12-14hr    25 embryo 14-16hr    21 embryo 16-18hr    17 embryo 18-20hr    13 embryo 20-22hr    7 embryo 22-24hr    7 larva L1    5 larva L2    2 larva L3 12hr old    1 larva L3 puffstage 1-2    2 larva L3 puffstage 3-6    5 larva L3 puffstage 7-9    7 white prepupae new    10 white prepupae 12hr    10 white prepupae 24hr    14 pupae 2d postWPP    12 pupae 3d postWPP    6 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    3 adult female 05day    2 adult female 30day    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1  26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1  26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    1 embryonic GM2    0 embryonic Kc167    0 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    26 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    0 ovary fGS/OSS    10 ovary OSC    0 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    3 cold shock, 4-day adult    2 heat shock, 4-day adult    1 Cadmium 50 mM 6 hrs, larvae L3    1 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    1 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    1 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    1 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_11 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085400 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13548-RA;CG30188-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG34371GD2175 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG34371 Class Mutagen Stocks Known lesion CG34371c01679 1 -- CG34371f06650 1 -- CG34371G8004 P-element activity 1 -- CG34371MB00740 1 -- CG34371MI04721 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG34371 Class Mutagen Stocks Known lesion CG34371GD12830 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG34371GD2175 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7177 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2175} NA P{GD12830} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}CG34371MI04721 NA PBac{PB}CG34371c01679 NA PBac{WH}CG34371f06650 NA insertion of enhancer trap binary system Mi{ET1}CG34371MB00740 No insertion of mobile activating element P{EP}CG34371G8004 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) gene_with_stop_codon_read_through (Jungreis et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG34371 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0085400
Orthologs
OrthoDB Orthologs (24) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6Z0BR2 Dipteran inclusive ortholog search EOG634WF2 Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search EOG6HQC05 Metazoa inclusive ortholog search EOG6KM9VS
Orthologs in Drosophila Species (EOG6Z0BR2)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG34371     Drosophila simulans   Dsim\GD25075     Drosophila erecta   Dere\GG20058     Drosophila yakuba   Dyak\GE11597     Drosophila ananassae   Dana\GF13311     Drosophila pseudoobscura pseudoobscura   Dpse\GA24669     Drosophila persimilis   Dper\GL11291     Drosophila willistoni   Dwil\GK19588     Drosophila virilis   Dvir\GJ20976     Drosophila mojavensis   Dmoj\GI21128     Drosophila grimshawi   Dgri\GH23057
Orthologs in non-Drosophila Dipterans (EOG634WF2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005560   Anopheles gambiae Malaria mosquito  Agam\AGAP001925   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015257
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG6KM9VS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021747gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_012355gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024881gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028889gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017023gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007016gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008771gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_021904gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_014031gn Y Danio rerio Zebrafish  Drer\ENSDARG00000086799 Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	33274 w1118; P{EP}CG34371G8004/SM6a 37845 y1 w*; Mi{MIC}CG34371MI04721 22886 y1 w67c23; Mi{ET1}CG34371MB00740
Harvard	- PBac{PB}CG34371c01679 - PBac{WH}CG34371f06650
VDRC	v22709 w1118; P{GD12830}v22709 v22710 w1118; P{GD12830}v22710 v44997 w1118; P{GD2175}v44997/TM3 v44998 w1118; P{GD2175}v44998/CyO
Genomic Clones ( 1 )
	BACR34K16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 107 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE72153
Other clones	LP15943 RT01604
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE16605
Other clones	56765 64040 79326 102859 166018 214379.35 CK01.13C.G12 CK01.18B.D11 CK01.56C.C12 CK01.66D.H4 EK014458 EK045733 EK054062 EK168939 EK190626 EK208910 EK224523 EP19745 FGM301E03 FGM305D01 RP003033776 RP003034086 RP003048820 RP003084052 RP003121923 RP003131432 RP003149686 RP003161454 RP003173788 RP003184152 RP003185422 RP003196777 RP003198284 RP003202443 RP003203754 RP003203817 RP003205060 RP003208514 RP003216256 RP003222923 RP003231167 RP003231402 RP003231803 RP003241892 RP003244902 RP003247489 RP003253935 RP003259361 RP003260401 RP003262881 RP003264883 RP003268438 RP003270335 RP003279483 RP003283717 RP003300827 RP003307264 RP003322781 RP003324460 RP003330380 RP003330538 RP003330748 RP003332294 RP003335450 RP003341378 RP003341544 RP003343823 RP003345695 RP003349804 RP003351980 RP003379032 RP003406475 RP003428936 RP003445853 RP003446154 RP003452566 RP003459345 RP003466892 RP003469579 RP003469925 RP003474501 RP003477674 RP003485852 RP003498192 RP003529371 RP003531287 RP003531350 RP003539178 RP003546806 RP003561970 RP003582574 RP003592797 RP003604457 RP003619101 RP003635658 RP003659216 RP003660843 RP003663564 RP003664972 RP003667339 RP003669665 RP003682150 UT01605
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0085400 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37679
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG13546 CG13547 (FlyBase Genome Annotators, 2002-2003) Source for merge of: CG13548 CG30188 (FlyBase Genome Annotators, 2007)
Additional comments	Annotations CG13548 and CG30188 merged as CG34371 in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007) Annotations CG13546 and CG13547 merged as CG30188 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_137921 NM_137923 RefSeq (Proteins) • NP_611765 NP_611767 DDBJ / EMBL / GenBank • AAF46965 AAF46967 Entrez Gene - A searchable database of RefSeq genes. • 37679 UniProtKB/TrEMBL • Q9W1T6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • CD80-like, immunoglobulin C2-set (IPR013162) Immunoglobulin-like domain (IPR007110) Fibronectin, type III (IPR003961) Immunoglobulin subtype (IPR003599) Immunoglobulin subtype 2 (IPR003598) Immunoglobulin-like fold (IPR013783) Immunoglobulin V-set (IPR013106)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0085400 DRSC - Results from RNAi screens. • FBgn0085400 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085400 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13548-RA;CG30188-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0085400 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37679 modMine - Data generated by the modENCODE project. • FBgn0085400
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG13546   CG13547   CG13548   CG30188 (Firth and Baker, 2007) CG34371 (FlyBase Genome Annotators, 2007, Jungreis et al., 2011) CT32921 (Hynes and Zhao, 2000) CT32922 (Hynes and Zhao, 2000)
Name Synonym	CG13548   CG30188
Secondary FlyBase IDs
	FBgn0034830 FBgn0034831 FBgn0034832 FBgn0050188
References ( 19 )
Research paper	Firth and Baker, 2007, Dev. Biol. 307(2): 521--538 Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. [FBrf0201413] Vogel et al., 2003, Development 130(25): 6317--6328 The immunoglobulin superfamily in Drosophila melanogaster and Caenorhabditis elegans and the evolution of complexity. [FBrf0167517]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 29. Summary of A-to-I RNA Editing Sites Discovered. [FBrf0213715] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Jungreis et al., 2011, Genome Res. 21(12): Supplemental Material. [FBrf0216884] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Hynes and Zhao, 2000, J. Cell Biol. 150(2): Table S3. proteins containing Ig domains alone. [FBrf0132107] Hynes and Zhao, 2000, J. Cell Biol. 150(2): Table S2. Proteins containing 1 or 2 Ig domains alone. [FBrf0132106]
Personal communication to FlyBase	Bellen, 2012.2.2, set970.xml set970.xml [FBrf0217351] Bellen, 2010.12.22, GE836.xml GE836.xml [FBrf0212684] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Zhao, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126701]