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Gene Dmel\Rgk3

General Information
Symbol	Dmel\Rgk3	Species	D. melanogaster
Name	Rgk3	Annotation symbol	CG34397
Feature type	protein_coding_gene	FlyBase ID	FBgn0085426
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	57D5-57D6	Sequence location	2R:17,143,319..17,167,878 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Rgk3 is referred to in FlyBase by the symbol Dmel\Rgk3 (CG34397, FBgn0085426). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTP binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: small GTPase mediated signal transduction. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ras; Small GTPase superfamily. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. Gene sequence location is 2R:17143319..17167878.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Transgenic Constructs P{GD15203}
FB2012_01	Sequence features HFA04255 HFA04251 HFA04250 BKN34054 HFA04254 BKN32434
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 57D5-57D6   Limits computationally determined from genome sequence between P{EP}CG4266EP2258 and P{EP}CG30394EP962&P{lacW}domk08108
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Rgk3 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Rgk3-RC FBtr0112646  NM_001103925   2524   449 Rgk3-RD FBtr0305983     2808   421
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Rgk3-PC   FBpp0111558   49.4   449   9.81     NP_001097395   ABV53867 Rgk3-PD   FBpp0297125   46.9   421   8.74
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ras (IPR013753) Small GTPase superfamily (IPR001806)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 ABV53867   BT022330   BT025135   BT031236   BT100204   CO189506   CO271340   CO279470   CO281193   CO317108   CO319809   CO322363   CO325426   CO329310   CO330798   CO334115   CO343236   CO344112   EC072208   EC073219   EC078082   EC079465   EC080707   EC203302   EC211917   EC215899   EC216361   EC239306   EL872534   EL872780   EL876934   EL877016   EL877214   EL877215   EL877216   EL877217
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0085426    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0085426 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0085426 expression level Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr  (1084) embryo 16-18hr  (2786) embryo 18-20hr  (2145) embryo 20-22hr  (628) embryo 22-24hr  (643) larva L1  (636) larva L2  (470) larva L3 12hr old  (418) larva L3 puffstage 1-2  (147) larva L3 puffstage 3-6  (205) larva L3 puffstage 7-9  (1067) white prepupae new  (1798) white prepupae 12hr  (351) white prepupae 24hr  (112) pupae 2d postWPP  (1052) pupae 3d postWPP  (2320) pupae 4d postWPP  (441) adult male 01day  (904) adult male 05day  (1116) adult male 30day  (1062) adult female 01day  (482) adult female 05day  (180) adult female 30day  (235) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr  (2786) embryo 18-20hr  (2145) embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new  (1798) white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP  (2320) pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0085426 expression level Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr  (1084) embryo 16-18hr  (2786) embryo 18-20hr  (2145) embryo 20-22hr  (628) embryo 22-24hr  (643) larva L1  (636) larva L2  (470) larva L3 12hr old  (418) larva L3 puffstage 1-2  (147) larva L3 puffstage 3-6  (205) larva L3 puffstage 7-9  (1067) white prepupae new  (1798) white prepupae 12hr  (351) white prepupae 24hr  112 pupae 2d postWPP  (1052) pupae 3d postWPP  (2320) pupae 4d postWPP  (441) adult male 01day  (904) adult male 05day  (1116) adult male 30day  (1062) adult female 01day  (482) adult female 05day  (180) adult female 30day  (235) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr  (2786) embryo 18-20hr  2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new  1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP  2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    11 embryo 02-04hr    9 embryo 04-06hr    10 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    17 embryo 12-14hr    77 embryo 14-16hr    1084 embryo 16-18hr    2786 embryo 18-20hr    2145 embryo 20-22hr    628 embryo 22-24hr    643 larva L1    636 larva L2    470 larva L3 12hr old    418 larva L3 puffstage 1-2    147 larva L3 puffstage 3-6    205 larva L3 puffstage 7-9    1067 white prepupae new    1798 white prepupae 12hr    351 white prepupae 24hr    112 pupae 2d postWPP    1052 pupae 3d postWPP    2320 pupae 4d postWPP    441 adult male 01day    904 adult male 05day    1116 adult male 30day    1062 adult female 01day    482 adult female 05day    180 adult female 30day    235 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0085426    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0085426 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: No expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085426 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CT35843;CG15660-RA;CG15664-RA;CG15663-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Rgk3GD5027 Rgk3GD15203 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Rgk3 Class Mutagen Stocks Known lesion Rgk3MI02734 1 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Rgk3 Class Mutagen Stocks Known lesion Rgk3GD5027 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rgk3KK112434 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rgk3GD12881 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Rgk3GD15203 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6074 (Ryder, 2004.4.26) Df(2R)Exel6075 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5027} NA P{GD12881} NA P{KK112434} NA characterization construct P{GD15203} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}Rgk3MI02734 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data on: 2006-05-23)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
GTP binding inferred from sequence or structural similarity with NCBI:NP_492856 (FlyBase, 1992-)
Biological Process
CV term Evidence References
small GTPase mediated signal transduction inferred from electronic annotation with InterPro:IPR001806 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Rgk3 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 625077 DroID - A comprehensive database of gene and protein interactions. • FBgn0085426 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 5740446
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs	Dpse\GA13877
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP005243-PA Anopheles gambiae (mosquito) XP_393394.2 Apis mellifera (honey bee) XP_001945205.1 Acyrthosiphon pisum (pea aphid) XP_001896591.1 Brugia malayi (roundworm nematode) ENSCAFP00000010379 Canis familiaris (dog) JA06247 Caenorhabditis japonica (nematode) ENSGALP00000034605 Gallus gallus (chicken) ENSP00000201979 Homo sapiens (human) ENSMMUP00000006780 Macaca mulatta (rhesus monkey) ENSMUSP00000034351 Mus musculus (house mouse) XP_001600145.1 Nasonia vitripennis (wasp) PP19742 Pristionchus pacificus (nematode) ENSPPYP00000012159 Pongo pygmaeus (orangutan) 83467 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000022894 Pan troglodytes (chimpanzee) ENSRNOP00000016259 Rattus norvegicus (norway rat) Smp_059570 Schistosoma mansoni (trematode parasite) XP_968810.1 Tribolium castaneum (red flour beetle) ENSTRUP00000025706 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12980 NV17312 LH15727 FBgn0229949 FBgn0217801 FBgn0209205 FBgn0183322 FBgn0170740 JGI_V11_307133 FBgn0246074 FBgn0143100 FBgn0129324 FBgn0114280 FBgn0089841 CPIJ013268 CPIJ019877 BGIBMGA011875 ACYPI009564 GB10589 AGAP005243 AAEL014340 PHUM565990 GLEAN_03414
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	35129 y1 w*; Mi{MIC}Rgk3MI02734
VDRC	v106428 P{KK112434}VIE-260B v15445 w1118; P{GD5027}v15445
Genomic Clones ( 2 )
	BACR12O13 BACR48K03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 33 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP04543
Other clones	IP07054 IP21963 MIP07271
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	20726 38961 62748 125626 163119 175915 190083 193294 283628 CK01.54D.G3 EK044426 EK103103 EK134561 EK156152 EK187962 EK196505 EK267136 EK280911 EK292538 EK296213 EK308934 EP16351 EP18704 IP04443 IP04643 IP06853 IP06953 IP07153 IP07154
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0085426 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37424 37425 5740446
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Rgk3 CG15663 CG15664 (Smibert and Saint, 2003)
Source for database merge of	Source for merge of: Rgk3 CG15660 (FlyBase Genome Annotators, 2007)
Additional comments	Annotations CG33949 and CG15660 merged as CG34397 in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007) Annotations CG15663 and CG15664 merged as CG33949 (which corresponds to Rgk3) in release 4.2 of the genome annotation. (FlyBase Genome Annotators, 2005)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001103925 RefSeq (Proteins) • NP_001097395 DDBJ / EMBL / GenBank • ABV53867 Entrez Gene - A searchable database of RefSeq genes. • 5740446
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ras (IPR013753) Small GTPase superfamily (IPR001806)
Linkouts
	BioGRID - A database of protein and genetic interactions • 625077 DroID - A comprehensive database of gene and protein interactions. • FBgn0085426 DRSC - Results from RNAi screens. • FBgn0085426 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085426 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CT35843;CG15660-RA;CG15664-RA;CG15663-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0085426 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37424 37425 5740446 InParanoid A subset of ortholog calls from InParanoid. • AGAP005243-PA Anopheles gambiae (mosquito) XP_393394.2 Apis mellifera (honey bee) XP_001945205.1 Acyrthosiphon pisum (pea aphid) XP_001896591.1 Brugia malayi (roundworm nematode) ENSCAFP00000010379 Canis familiaris (dog) JA06247 Caenorhabditis japonica (nematode) ENSGALP00000034605 Gallus gallus (chicken) ENSP00000201979 Homo sapiens (human) ENSMMUP00000006780 Macaca mulatta (rhesus monkey) ENSMUSP00000034351 Mus musculus (house mouse) XP_001600145.1 Nasonia vitripennis (wasp) PP19742 Pristionchus pacificus (nematode) ENSPPYP00000012159 Pongo pygmaeus (orangutan) 83467 Phytophthora ramorum (sudden oak death pathogen) ENSPTRP00000022894 Pan troglodytes (chimpanzee) ENSRNOP00000016259 Rattus norvegicus (norway rat) Smp_059570 Schistosoma mansoni (trematode parasite) XP_968810.1 Tribolium castaneum (red flour beetle) ENSTRUP00000025706 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 5740446 modMine - Data generated by the modENCODE project. • FBgn0085426 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12980 NV17312 LH15727 FBgn0229949 FBgn0217801 FBgn0209205 FBgn0183322 FBgn0170740 JGI_V11_307133 FBgn0246074 FBgn0143100 FBgn0129324 FBgn0114280 FBgn0089841 CPIJ013268 CPIJ019877 BGIBMGA011875 ACYPI009564 GB10589 AGAP005243 AAEL014340 PHUM565990 GLEAN_03414
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG15660   CG15663 (Giot et al., 2003, ) CG15664   CG33949   CG34397 (FlyBase Genome Annotators, 2007, Keleman et al., 2009.8.5) Rgk3
Name Synonym	CG15660   Rgk3
Secondary FlyBase IDs
	FBan0015663 FBan0015664 FBgn0034608 FBgn0034609 FBgn0034610 FBgn0053949
References ( 17 )
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2011.3.29, set930.xml set930.xml [FBrf0213349] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Roth and Foulger, 2002.4.24, Predicted GO terms. Predicted GO terms. [FBrf0146674]
Abstract	Smibert and Saint, 2003, A. Dros. Res. Conf. 44: 226A Characterisation of the developmental and cellular roles of the Drosophila melanogster RGK GTPase family. [FBrf0154543]
FlyBase analysis	FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Genome Annotators, 2005, Changes affecting gene model number or type in release 4.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 4.2 of the annotated D.melanogaster genome. [FBrf0182792] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Curated genome annotation	Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126651]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]