Gene model reviewed during 5.46
Stop-codon suppression (UGA) postulated; FBrf0234051.
Gene model reviewed during 6.25
A non-AUG start codon may be used for translation of one or more transcripts of this gene; based on the presence of conserved protein signatures within the 5' UTR without an in-frame AUG (FBrf0243886).
None of the polypeptides share 100% sequence identity.
Component of the SCF-like E3 ubiquitin-protein ligase complex.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dora using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Dora in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Dora CG34401
The gene is named 'Dorado' after a fish that preys on octopuses from the Argonauta genus, as the gene and its orthologs are proposed to mediate target-directed miRNA degradation (TDMD) through the ubiquitination of an Argonaute protein.