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Gene Dmel\CG34439

General Information
Symbol	Dmel\CG34439	Species	D. melanogaster
Name		Annotation symbol	CG34439
Feature type	protein_coding_gene	FlyBase ID	FBgn0085468
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	49F4-49F4	Sequence location	2R:9,046,171..9,047,695 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG34439 (FBgn0085468). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult salivary gland, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1629902_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG34439 expression signal. See the GBrowse view of CG34439 to determine the overlapping gene(s). Gene sequence location is 2R:9046171..9047695.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 49F4-49F4
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG34439 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG34439-RA FBtr0112740  NM_001103826   384   73 CG34439-RB FBtr0112741  NM_001103827   728   123
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG34439-PA   FBpp0111652   8.6   73   6.75     NP_001097296   ABV53784 CG34439-PB   FBpp0111653   14.9   123   9.32     NP_001097297   ABV53785
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 (IPR017384)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 ABV53784   AE013599 ABV53785   AY061306   AY075548   BE978398   BI243422   BI368028   BI375890   BI482018   BI579538   BI635015   BT058009   CO274874   CO274891   CO305738   CO322682   CO325476   CZ466193   CZ466199   CZ478614   EC065901   EC071458   EC074560   EC204465   EC227323   EC237915   EC243330   ES690573   EV579056   EV585167   EV588187   EV593283   EV597217
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	A8DYC4 A8DYC5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult salivary gland, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    158 Larval Midgut    33.6 Larval Hindgut    50.7 Larval Malpighian Tubules    39.6 Larval Fat Body    73.8 Larval Salivary Gland    71.1 Larval Trachea    52.4 Larval Carcass    59.95 Adult Head    31.3 Adult Eye    13.825 Adult Brain    59.7 Adult Thoracic-Abdominal Ganglion    56.8 Adult Crop    44.7 Adult Midgut    50.5 Adult Hindgut    52.2 Adult Malpighian Tubules    30.1 Adult Fat Body    42.5 Adult Salivary Gland    113.6 Adult Heart    9.3 Adult VirginFemale Spermatheca    25.2 Adult InseminatedFemale Spermatheca    34.1 Adult Ovary    223.7 Adult Testis    98.3 Adult Male Accessory Gland    54.7 Adult Carcass    56.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    31.3   NA  Eye    no informative data   NA  Brain    59.7   158  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    56.8   NA  Crop    44.7   33.6  Midgut    50.5   50.7  Hindgut    52.2   39.6  Malpighian Tubules    30.1   73.8  Fat Body    no informative data   71.1  Salivary Gland    113.6   NA  Heart    9.3   52.4  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    223.7   NA  Testis    98.3   NA  Male Accessory Gland    54.7   59.95  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male    108 accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (33) central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male  (28) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8  (77) carcass, larvae L3 wandering    8 carcass, 1-day adult  (37) carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male  (108) accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male  (108) accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male    108 accessory gland, mated 4-day male    24 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male    108 accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (33) central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male  28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8  (77) carcass, larvae L3 wandering    8 carcass, 1-day adult  (37) carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male  (108) accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male  108 accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    33 central nervous system, larvae L3    9 central nervous system, pupae P8    10 head, virgin 1-day female    16 head, virgin 4-day female    12 head, virgin 20-day female    13 head, mated 1-day female    18 head, mated 4-day female    14 head, mated 20-day female    12 head, mated 1-day male    24 head, mated 4-day male    23 head, mated 20-day male    28 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    18 digestive system, 4-day adult    16 digestive system, 20-day adult    13 fat body, larvae L3 wandering    6 fat body, white prepupae    21 fat body, pupae P8    77 carcass, larvae L3 wandering    8 carcass, 1-day adult    37 carcass, 4-day adult    21 carcass, 20-day adult    14 ovary, virgin 4-day female    10 ovary, mated 4-day female    9 testis, mated 4-day male    108 accessory gland, mated 4-day male    24 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP    101 adult male 01day    106 adult male 05day    110 adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (27) embryo 02-04hr    25 embryo 04-06hr  (34) embryo 06-08hr    24 embryo 08-10hr  (28) embryo 10-12hr  (37) embryo 12-14hr  (30) embryo 14-16hr  (33) embryo 16-18hr  (58) embryo 18-20hr  (36) embryo 20-22hr  (40) embryo 22-24hr  (51) larva L1  (76) larva L2  (64) larva L3 12hr old  (49) larva L3 puffstage 1-2  (35) larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr  (29) white prepupae 24hr  (34) pupae 2d postWPP  (46) pupae 3d postWPP  (80) pupae 4d postWPP  (101) adult male 01day  (106) adult male 05day  (110) adult male 30day  (68) adult female 01day  (85) adult female 05day  (38) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP  101 adult male 01day  106 adult male 05day  (110) adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP    101 adult male 01day    106 adult male 05day    110 adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP    101 adult male 01day    106 adult male 05day    110 adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  27 embryo 02-04hr    25 embryo 04-06hr  (34) embryo 06-08hr    24 embryo 08-10hr  28 embryo 10-12hr  (37) embryo 12-14hr  30 embryo 14-16hr  (33) embryo 16-18hr  (58) embryo 18-20hr  (36) embryo 20-22hr  (40) embryo 22-24hr  (51) larva L1  (76) larva L2  (64) larva L3 12hr old  (49) larva L3 puffstage 1-2  (35) larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr  29 white prepupae 24hr  (34) pupae 2d postWPP  (46) pupae 3d postWPP  (80) pupae 4d postWPP  (101) adult male 01day  (106) adult male 05day  (110) adult male 30day  (68) adult female 01day  (85) adult female 05day  (38) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP  101 adult male 01day  106 adult male 05day  110 adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    27 embryo 02-04hr    25 embryo 04-06hr    34 embryo 06-08hr    24 embryo 08-10hr    28 embryo 10-12hr    37 embryo 12-14hr    30 embryo 14-16hr    33 embryo 16-18hr    58 embryo 18-20hr    36 embryo 20-22hr    40 embryo 22-24hr    51 larva L1    76 larva L2    64 larva L3 12hr old    49 larva L3 puffstage 1-2    35 larva L3 puffstage 3-6    22 larva L3 puffstage 7-9    25 white prepupae new    23 white prepupae 12hr    29 white prepupae 24hr    34 pupae 2d postWPP    46 pupae 3d postWPP    80 pupae 4d postWPP    101 adult male 01day    106 adult male 05day    110 adult male 30day    68 adult female 01day    85 adult female 05day    38 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  (30) embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1  (34) embryonic S3  (34) leg disc CME L1  (36) wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9  26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11  (41) antennal disc ML-DmD20-c5  (30) mixed discs ML-DmD4-c1  (29) CNS ML-DmBG1-c1  (35) CNS ML-DmBG2-c2  (29) tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (48) Schneider line 2 Sg4  30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1  (34) embryonic S3  (34) leg disc CME L1  (36) wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9  26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11  (41) antennal disc ML-DmD20-c5  30 mixed discs ML-DmD4-c1  29 CNS ML-DmBG1-c1  (35) CNS ML-DmBG2-c2  29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    48 Schneider line 2 Sg4    30 embryonic 1182-4H    15 embryonic GM2    18 embryonic Kc167    15 embryonic S1    34 embryonic S3    34 leg disc CME L1    36 wing disc CME-W2    24 wing disc ML-DmD8    18 wing disc ML-DmD9    26 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    23 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    22 eye-antennal disc ML-DmD11    41 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    29 CNS ML-DmBG1-c1    35 CNS ML-DmBG2-c2    29 tumorous blood cells mbn2    22 ovary fGS/OSS    12 ovary OSC    15 ovary OSS    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult  (27) Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult  (33) Ethanol 2.5% 3 hrs, larvae L3  (29) Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3  (31) Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  (31) Paraquat 10 mM 48 hrs, 4-day adult  (30) Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult  27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult  (33) Ethanol 2.5% 3 hrs, larvae L3  29 Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3  31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  31 Paraquat 10 mM 48 hrs, 4-day adult  30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3  (36) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    10 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    21 Cadmium 50 mM 48 hrs, 4-day adult    23 Cadmium 100 mM 48 hrs, 4-day adult    20 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    22 Zinc 4.5 mM 48 hrs, 4-day adult    33 Ethanol 2.5% 3 hrs, larvae L3    29 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    31 Caffeine 1.5 mg/ml 4 hrs, larvae L3    19 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    31 Paraquat 10 mM 48 hrs, 4-day adult    30 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    36 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_15 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085468
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive CG34439c00093 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of CG34439 Class Mutagen Stocks Known lesion CG34439c00093 piggyBac transposase 2 -- CG34439k14301 2 Yes CG34439e00771 piggyBac transposase 1 -- CG34439G2759 P-element activity 1 -- CG34439c00105 piggyBac transposase 0 -- CG34439DG04101 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG34439 Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{wHy}CG34439DG04101 NA PBac{PB}CG34439c00093 NA PBac{PB}CG34439c00105 NA PBac{RB}CG34439e00771 NA insertion of mobile activating element P{EP}NrkG2759 NA insertion of enhancer trap P{lacW}Nrkk14301 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a biological process or molecular function term for this gene. (Based on a review of available data on: 2008-03-06)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
mitochondrial respiratory chain complex I inferred from sequence or structural similarity with human NDUFS1 (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene (FlyBase, 1992-) protein_coding_gene (FlyBase, 1992-)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG34439 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0085468
Orthologs
OrthoDB Orthologs (18) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG66DMPN Dipteran inclusive ortholog search EOG69KG18 Insect inclusive ortholog search EOG6FTTXX Arthropod inclusive ortholog search EOG6547GX Metazoa inclusive ortholog search EOG60PH44
Orthologs in Drosophila Species (EOG66DMPN)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG34439     Drosophila pseudoobscura pseudoobscura   Dpse\GA24655     Drosophila persimilis   Dper\GL11235     Drosophila mojavensis   Dmoj\GI19985
Orthologs in non-Drosophila Dipterans (EOG69KG18)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010673   Anopheles gambiae Malaria mosquito  Agam\AGAP006630   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ014797
Orthologs in non-Dipteran Insects (EOG6FTTXX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005608   Atta cephalotes Leafcutter ant  Acep\ACEP27511   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19263   Linepithema humile Argentine ant  Lhum\LH21899   Pogonomyrmex barbatus Red harvester ant  Pbar\PB16171   Solenopsis invicta Red fire ant  Sinv\SINV18318   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001322   Tribolium castaneum Red flour beetle  Tcas\TC012474   Tribolium castaneum Red flour beetle  Tcas\TC004750
Orthologs in non-Insect Arthropods (EOG6547GX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_322524
Orthologs in non-Arthropod Metazoa (EOG60PH44)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F31D4.9
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	10008 w1118; PBac{PB}CG34439c00093/CyO 28454 y1 w*; P{EP}NrkG2759 CG34439G2759 11122 y1 w67c23; P{lacW}Nrkk14301 CG34439k14301 TppIIk14301/CyO
Harvard	- PBac{PB}CG34439c00093 - PBac{RB}CG34439e00771
Kyoto	111339 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}42D P{lacW}Nrkk14301 /CyO y+
Genomic Clones ( 1 )
	BACR48I10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 26 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH20835 LD22256 RH49308
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE41061 RE53930 RE63791 RE64658 RE73584 SD01280
Other clones	62958 145259 146430 174147 bs78c05 CK01.142C.D4 CK01.142C.G1 Dmel_dig_005169_0593_2554 Dmel_dig_015035_0611_2670 Dmel_neb_009714_0173_3596 Dmel_neb_012908_0669_1459 Dmel_neb_014429_0837_2637 EK115825 EK115846 EK188635 EK196619 EK249330
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0085468 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740593
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Annotation CG17054 split into CG34438 (which corresponds to Cap-G) and CG34439 in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007) Annotations CG13328 and CG17054 merged as CG17054 in release 3.2 of the genome annotation. (FlyBase Genome Annotators, 2004)
Other Comments
	Annotation CG13328 was eliminated in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001103826 NM_001103827 RefSeq (Proteins) • NP_001097296 NP_001097297 DDBJ / EMBL / GenBank • ABV53784 ABV53785 CZ466193 CZ466199 CZ478614 Entrez Gene - A searchable database of RefSeq genes. • 5740593 UniProtKB/TrEMBL • A8DYC4 A8DYC5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 (IPR017384)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0085468 DRSC - Results from RNAi screens. • FBgn0085468 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0085468 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0085468 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740593 modMine - Data generated by the modENCODE project. • FBgn0085468
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	BcDNA:RH49308   CG13328 (Luschnig, 2003.12.17) CG17054 (Porcelli et al., 2007) CG30057   CG34439 (FlyBase Genome Annotators, 2007, Cammarato et al., 2011, Holland et al., 2011) l(2)c00093
Name Synonym	lethal (2) c00093   NADH ubiquinone oxidoreductase MWFE (Porcelli et al., 2007)
Secondary FlyBase IDs
	FBgn0033795 FBgn0033797 FBgn0050057 FBgn0061377
References ( 20 )
Research paper	Brooks et al., 2011, Genome Res. 21(2): 193--202 Conservation of an RNA regulatory map between Drosophila and mammals. [FBrf0213079] Holland et al., 2011, Genetics 188(2): 359--367 A Link Between Impaired Purine Nucleotide Synthesis and Apoptosis in Drosophila melanogaster. [FBrf0213875] Porcelli et al., 2007, BMC Evol. Biol. 7: 215 The nuclear OXPHOS genes in insecta: a common evolutionary origin, a common cis-regulatory motif, a common destiny for gene duplicates. [FBrf0204833] Thibault et al., 2004, Nat. Genet. 36(3): 283--287 A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac. [FBrf0175002]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979]
Personal communication to FlyBase	Bellen, 2009.8.20, BDGP_2009_0825.GenExel.xml BDGP_2009_0825.GenExel.xml [FBrf0208536] Gelbart, 2008.3.31, DG.xml DG.xml [FBrf0204101] Caggese, 2007.3.27, D. pseudoobscura OXPHOS genes. D. pseudoobscura OXPHOS genes. [FBrf0200156] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection. Deletion Generator Project genomic insertion collection. [FBrf0188490] Luschnig, 2003.12.17, Existence-uncertain genes. Existence-uncertain genes. [FBrf0173248]
FlyBase analysis	Curators, 2008--, Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. [FBrf0202953] FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Genome Annotators, 2004, Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. [FBrf0166453] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]