• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\lmgB

General Information
Symbol	Dmel\lmgB	Species	D. melanogaster
Name	lemming B	Annotation symbol	CG34441
Feature type	protein_coding_gene	FlyBase ID	FBgn0085470
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	29D4-29D5	Sequence location	2L:8,524,999..8,528,505 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene lemming B is referred to in FlyBase by the symbol Dmel\lmgB (CG34441, FBgn0085470). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: FAM89. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1639494_at aligns to a genomic region shared by exons of 2 FlyBase-annotated genes; hence it is impossible to interpret the expression pattern and levels of CG34441 expression signal. See the GBrowse view of CG34441 to determine the overlapping gene(s). Gene sequence location is 2L:8524999..8528505.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29D4-29D5
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\lmgB for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Gene model reviewed during 5.48 gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) lmgB-RA FBtr0112744  NM_001103654   2953   365 lmgB-RB FBtr0112745  NM_001103655   1901   365 lmgB-RC FBtr0333420  NM_001273330   3507   365 lmgB-RD FBtr0336886  NM_001273331   1462   365
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein lmgB-PA   FBpp0111656   37.7   365   10.37     NP_001097124   ABV53652 lmgB-PB   FBpp0111657   37.7   365   10.37     NP_001097125   AAF52694 lmgB-PC   FBpp0305612   37.7   365   10.37     NP_001260259   AGB92795 lmgB-PD   FBpp0307834   37.7   365   10.37     NP_001260260   AGB92796
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • FAM89 (IPR026654)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202488   AA263544   AA263946   AA536351   AA539176   AA539465   AA540926   AA951306   AE014134 AAF52694   AE014134 ABV53652   AE014134 AGB92795   AE014134 AGB92796   AI389092   AI455979   AI514960   AI516596   AI518467   AI520119   AI520124   AI534465   AQ025610   AY089284   BG633098   BG639218   BI162858   BI166262   BI167608   BI170391   BI215418   BI236624   BI237241   BI238080   BI241518   BI242483   BI483804   BI485673   BI580942   BI617867   BI619599   CK659004   CO263041   CO267513   CO283951   CO285074   CO285352   CO291459   CO294106   CO295088   CO297210   CO298884   CO300564   CO301606   CO305825   CO310054   CO316521   CO319391   CO332196   CW848176   CZ476712   EC059046   EC062355   EC062547   EC063890   EC064602   EC066012   EC078386   EC081901   EC082072   EC082094   EC087086   EC089382   EC090618   EC194591   EC196782   EC196800   EC199175   EC234662   EC245716   EC252962   EV585404   GH747838   GH748024   GH748110   GH748126   GH749456   GH749753   GH750009   GH750170   GH752669   GH753472   GH753891   GH753921   GH755121   GH755251   GH756814   GH757819   GH757921   GH758030   GH770440   GH770650   GH771292   GH771326   GH771528   GH771639   GH771767   GH772260   GH775579   GH775920   GH777042   GH778303   GH778310   GH778319   GH778484   GH778948   GH779007   GH779951   GH780258   GH780337   GH781041   GH781644   GH781669   GH781837   GH782047   GH783717   GH784334   GH784844   GH785815   GH786136   GH786577   GH786927   GH787101   GH787651   GH789352   GH789785   GH789867   GH790560   GH792361   GH792578   GH792587   GH794772   GH794877   GH796486   GH796870   GH796982   GH798427   GH799049   GH799312   GH799806   GH801393   GH802170   GH803689   GH804185   GH804240   GH806524   GH806816   GH808000   GH808078   GH808172   GH808316   GH808367   GH809970   GH810305   GH810489   GH811417   GH811596   GH812060   GH812477   GH812572   GH812718   GH812913   GH813032   GH813416   GH814817   GH815152   GH815309   GH815695   GH815999   GH817373   GH818430   GH819629   GH820036   GH821009   GH822956   GH823121   GH824388   GH825511   GH826237   GH826505   GH827319   GH830472   GH831929   GH832188   GH832619   GH832715   GH833157   GH833273   GH835170   GH836147   GH837180   GH837876   GH840484   GH841754   GH841800   GH842938   GH844064   GH844234   GH847075   GH847922   GH848201   GH848520   GH850663   GH851107   GH852381   GH852431   GH852840   GH853458   GH853480   GH853919   GH854033   GH854219   GH855015   GH855286   GH855631   GH855953   GH856551   GH856660   GH857543   GH857718   GH860453   GH860460   GH861465   GH861731   GH863565   GH863908   GH865721   GH866276   GH866842   GH868682   GH868786   GH869085   GH869565   GH872317   GH872641   GH872760   GH875576   GH876952   GH877390   GH878911   GH878927   GH880554   GH881300   GH881509   GH882888   GH882946   GH883164   GH883665   GH884182   GH884250   GH884304   GH884611   GH885817   GH885902   GH886382   GH887262   GH887446   GH888492   GH888853   GH889252   GH889322   GH889746   GH891134   GH891247   GH891733   GH895243   GH896838   GH897242   GH897403   GH898153   GH898838   GH899048   GH900857   GH902788   GH903362   GH903772   GH904430   GH905247   GH905552   GH905866   GH905875   GH906111   GH906375   GH906411   GH907881   GH908899   GH909416   GH909522   GH909745   GH910245   GH911967   GH912194   GH912276   GH912902   GH913950   GH914129   GH915115   GH915960   GH916843   GH918706   GH918743   GH919099   GH919535   GH919808   GH921735   GH922467   GH922604   GH923474   GH924170   GH924936   GH927066   GH927223   GH927455   GH928992   GH929175   GH929694   GH929825   GH931000   GH931777   GH932043   GH933048   GH933567   GH933733   GH934719   GH935898   GH936320   GH943125   GH943578   GH945174   GH946122   GH946744   GH947321   GH947692   GH947726   GH948459   GH949363   GH949496   GH950528   GH950582   GH951031   GH951759   GH952600   GH952737   GH953343   GH953420   GH953884   GH954642   GH954735   GH955474   GH955561   GH955700   GH956012   GH956088   GH956114   GH956245   GH956947   GH956969   GH957165   GH957429   GH957448   GH958520   GH959024   GH959098   GH959242   GH960661   GH961283   GH961311   GH961766   GH961802   GH961848   GH961903   GH962294   GH962999   GH963195   GH963205   GH963676   GH964537   GH965013   GH965331   GH965712   GH966556   GH967926   GH969594   GH969780   GH969878   GH970527   GH970661   GH970807   GH971187   GH971193   GH971430   GH971664   GH972774   GH972878   GH973759   GH974083   GH975751   GH975935   GH976108   GH976520   GH976551   GH976879   GH977078   GH977129   GH977216   GH977316   GH978138   GH978468   GH979237   GH979330   GH979611   GH980189   GH981226   GH981600   GH982273   GH982303   GH982311   GH982413   GH982879   GH983508   GH984072   GH984258
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VLJ5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    91.1 Larval Midgut    34.1 Larval Hindgut    40 Larval Malpighian Tubules    59.5 Larval Fat Body    95.9 Larval Salivary Gland    84.8 Larval Trachea    44.075 Larval Carcass    58.925 Adult Head    46.8 Adult Eye    21.1 Adult Brain    63.8 Adult Thoracic-Abdominal Ganglion    39.7 Adult Crop    66 Adult Midgut    48 Adult Hindgut    40.4 Adult Malpighian Tubules    31.4 Adult Fat Body    47.3 Adult Salivary Gland    58.3 Adult Heart    34.975 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    41.1 Adult Ovary    211.6 Adult Testis    218.1 Adult Male Accessory Gland    49.9 Adult Carcass    42.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    46.8   NA  Eye    no informative data   NA  Brain    63.8   91.1  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    39.7   NA  Crop    66   no informative data  Midgut    48   40  Hindgut    40.4   59.5  Malpighian Tubules    31.4   95.9  Fat Body    47.3   84.8  Salivary Gland    no informative data   NA  Heart    34.975   44.075  Trachea    NA   NA  VirginFemale Spermatheca    38   NA  InseminatedFemale Spermatheca    41.1   NA  Ovary    211.6   NA  Testis    218.1   NA  Male Accessory Gland    49.9   58.925  Carcass    42.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  26 central nervous system, larvae L3    21 central nervous system, pupae P8  (35) head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female  (28) ovary, mated 4-day female  26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  26 central nervous system, larvae L3    21 central nervous system, pupae P8  (35) head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female  28 ovary, mated 4-day female  26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    26 central nervous system, larvae L3    21 central nervous system, pupae P8    35 head, virgin 1-day female    5 head, virgin 4-day female    5 head, virgin 20-day female    5 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    4 head, mated 1-day male    9 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    4 digestive system, 1-day adult    2 digestive system, 4-day adult    4 digestive system, 20-day adult    4 fat body, larvae L3 wandering    3 fat body, white prepupae    7 fat body, pupae P8    13 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    5 carcass, 20-day adult    5 ovary, virgin 4-day female    28 ovary, mated 4-day female    26 testis, mated 4-day male    8 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (37) embryo 02-04hr  (56) embryo 04-06hr  (38) embryo 06-08hr  (31) embryo 08-10hr  (30) embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (37) embryo 02-04hr  (56) embryo 04-06hr  (38) embryo 06-08hr  31 embryo 08-10hr  30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    37 embryo 02-04hr    56 embryo 04-06hr    38 embryo 06-08hr    31 embryo 08-10hr    30 embryo 10-12hr    22 embryo 12-14hr    24 embryo 14-16hr    22 embryo 16-18hr    21 embryo 18-20hr    15 embryo 20-22hr    19 embryo 22-24hr    19 larva L1    8 larva L2    8 larva L3 12hr old    6 larva L3 puffstage 1-2    6 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    14 white prepupae new    15 white prepupae 12hr    15 white prepupae 24hr    20 pupae 2d postWPP    24 pupae 3d postWPP    19 pupae 4d postWPP    10 adult male 01day    10 adult male 05day    12 adult male 30day    11 adult female 01day    15 adult female 05day    23 adult female 30day    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    16 Schneider line 2 Sg4    12 embryonic 1182-4H    12 embryonic GM2    13 embryonic Kc167    19 embryonic S1    24 embryonic S3    14 leg disc CME L1    14 wing disc CME-W2    12 wing disc ML-DmD8    14 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    18 wing disc ML-DmD21    12 wing disc ML-DmD32    15 haltere disc ML-DmD17-c3    19 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    16 CNS ML-DmBG2-c2    9 tumorous blood cells mbn2    16 ovary fGS/OSS    16 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    9 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    21 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    8 Ethanol 2.5% 3 hrs, larvae L3    21 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    20 Caffeine 25 mg/ml 48 hrs, 4-day adult    9 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_09 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • AT07979
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of lmgB Class Mutagen Stocks Known lesion lmgB03424 1 Yes lmgBd09381 1 Yes lmgBEY11317 1 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of lmgB Class Mutagen Stocks Known lesion lmgBHMS02024 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes lmgBKK107738 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes lmgBAB.Scer\UAS in vitro construct - regulatory fusion 0 Yes lmgBGD15042 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes lmgBScer\UAS.cNa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Partially disrupted in	Df(2L)lmg138 (Nagy et al., 2012)
Disrupted in	Df(2L)lmgJ023 (Nagy et al., 2012)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.HMS02024} NA P{UAS-lmgAB.N} NA P{UAS-lmgB.N} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}lmgA03424 No insertion of mobile activating element P{EPgy2}lmgAEY11317 NA P{XP}lmgAd09381 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data on: 2012-10-19)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_dicistronic_mRNA (FlyBase Genome Annotators, 2007) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions lmgB allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68849 DroID - A comprehensive database of gene and protein interactions. • FBgn0085470
Orthologs
OrthoDB Orthologs (9) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6WH967 Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6WH967)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\lmgB     Drosophila simulans   Dsim\GD22392     Drosophila sechellia   Dsec\GM12825     Drosophila erecta   Dere\GG24062     Drosophila ananassae   Dana\GF14365     Drosophila willistoni   Dwil\GK18747     Drosophila virilis   Dvir\GJ17542     Drosophila mojavensis   Dmoj\GI17629     Drosophila grimshawi   Dgri\GH10767
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	40857 y1 v1; P{TRiP.HMS02024}attP40/CyO 11330 P{PZ}lmgA03424 lmgB03424 cn1/CyO; ry506 21361 y1 w67c23; P{EPgy2}lmgAEY11317 lmgBEY11317/CyO
Harvard	- P{XP}lmgAd09381
VDRC	v103649 P{KK107738}VIE-260B
Genomic Clones ( 2 )
	BACR02I15 BACR23B08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 419 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT07979
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD01986 LD06648 LD07333 LD16925 LD17281 LD17608 LD20119 LD31708 LD35752 LD37989 LD40102 LD40137 LD42511 LD46608 LD47256 LP16392 RE02111 RE06326 RE08028 RE11818 RE21815 RE32702 RE33431 RE34455 RE38608 RE39831 RE66751 RE69005 RE75192 RH48331 RH50667 SD07290
Other clones	38056 52613 52652 55066 57656 75188 79312 97681 147031 160978 173736 214377.6 275318 CK01.19B.D5 CK01.100B.G5 CK01.103D.E10 CK01.104B.E4 Dmel_dig_020850_0632_1854 EK079451 EK087149 EK150634 EK164903 EK168138 EK168821 EK174037 EK178614 EK181647 EK206018 EK208616 EK216407 EK220334 EK249516 EK265150 EK277950 EK302736 GH20177 RP003002348 RP003016578 RP003017066 RP003018140 RP003018795 RP003024298 RP003027785 RP003029091 RP003035533 RP003035810 RP003038360 RP003040022 RP003040521 RP003040832 RP003042993 RP003045277 RP003045417 RP003047416 RP003048131 RP003049849 RP003052444 RP003054514 RP003054662 RP003055250 RP003055953 RP003056497 RP003061319 RP003061819 RP003064957 RP003065432 RP003067386 RP003068880 RP003069367 RP003069897 RP003074872 RP003077237 RP003081731 RP003083334 RP003083645 RP003087232 RP003087500 RP003088688 RP003089006 RP003089123 RP003089819 RP003096381 RP003096806 RP003099273 RP003099331 RP003103253 RP003104442 RP003108304 RP003108409 RP003109035 RP003111459 RP003113049 RP003113666 RP003115281 RP003119183 RP003120053 RP003120554 RP003124728 RP003134123 RP003134649 RP003136167 RP003138256 RP003139671 RP003142068 RP003144105 RP003147045 RP003151522 RP003153174 RP003157131 RP003159091 RP003160507 RP003164897 RP003166191 RP003168295 RP003169826 RP003169927 RP003170513 RP003172344 RP003173041 RP003175552 RP003179951 RP003181148 RP003183169 RP003191692 RP003194886 RP003198267 RP003200733 RP003202968 RP003204748 RP003206482 RP003207481 RP003210611 RP003211840 RP003212318 RP003216789 RP003216799 RP003220647 RP003226882 RP003228523 RP003231085 RP003231556 RP003232737 RP003235918 RP003238108 RP003238463 RP003239389 RP003240610 RP003241780 RP003247023 RP003252160 RP003252487 RP003254496 RP003254726 RP003258114 RP003260765 RP003262854 RP003267075 RP003267337 RP003268077 RP003270609 RP003272623 RP003276943 RP003277241 RP003277927 RP003280021 RP003281525 RP003283390 RP003285672 RP003287287 RP003288525 RP003288699 RP003289041 RP003290932 RP003298189 RP003301646 RP003304254 RP003304786 RP003305588 RP003306420 RP003310805 RP003312687 RP003315069 RP003316987 RP003318054 RP003329115 RP003330415 RP003332570 RP003333736 RP003339902 RP003345209 RP003352959 RP003353750 RP003354824 RP003357300 RP003372970 RP003380145 RP003385375 RP003386392 RP003386835 RP003392328 RP003395079 RP003402102 RP003405369 RP003406839 RP003408526 RP003409208 RP003411069 RP003413209 RP003417651 RP003419520 RP003424521 RP003425066 RP003427759 RP003432536 RP003434993 RP003435838 RP003437319 RP003438143 RP003443855 RP003447329 RP003449629 RP003455404 RP003457404 RP003457939 RP003462057 RP003462954 RP003464531 RP003466592 RP003466921 RP003469526 RP003474137 RP003475748 RP003476747 RP003480635 RP003484289 RP003485846 RP003486119 RP003496355 RP003496758 RP003497990 RP003498902 RP003498959 RP003504525 RP003505149 RP003512191 RP003514039 RP003520007 RP003520975 RP003524267 RP003525698 RP003526911 RP003527836 RP003529836 RP003540176 RP003540395 RP003544300 RP003544832 RP003550652 RP003552280 RP003552616 RP003555976 RP003556659 RP003559035 RP003560607 RP003563947 RP003572927 RP003575338 RP003580242 RP003582783 RP003583503 RP003586435 RP003586781 RP003588804 RP003598188 RP003602340 RP003616798 RP003618146 RP003624414 RP003629769 RP003631229 RP003637724 RP003640460 RP003648191 RP003648247 RP003662338 RP003665883 RP003676765 RP003679473 RP003680573 RP003681613 RP004007711 RP004012903 RP004015510 RP004031233 RP004057850 RP004059135 RP004064349 RP004067625 RP004068666 RP004082810 RP004084601 RP004085212 RP004087250 RP004092666 RP004095071 RP004097183 RP004108647 RP004111258 RP004122660 RP004130037 RP004131231 RP004140160 RP004141860 RP004154471 RP004162794 RP004169224 RP004175698 RP004184753 RP004186325 RP004197613 RP004200507 RP004202649 RP004206084 RP004207145 RP004208417 RP004210768 RP004216585 RP004216768 RP004221174 RP004222273 RP004222618 RP004222966 RP004224798 RP004230298 RP004234488 RP004234552 RP004243600 RP004248765 RP004249252 RP004251646 RP004252229 RP004253482 RP004259631 RP004263738 RP004295455 RP004298954 RP004301116 RP004302977 RP004307812 RP004316808 RP004317553 RP004327176 RP004331651 RP004336024 RP004369782 RP004376183 RP004390004 RP004392218 RP004409302 RP004412502 RP004416029 RP004416079 RP004422134 RP004424187 RP004426066 RP004434215 RP004436778 RP004439113 RP004461395 RP004479698 RP004489338 RP004493546 RP004496659 RP004502796 RP004512005 RP004517188 RP004517779 RP004519168 RP004527156 RP004530243 RP004531230 RP004531314 RP004533388 RP004536843 RP004537271 RP004542216
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0085470 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44128
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: lmgB CG34441 (Nagy et al., 2012)
Source for database merge of
Additional comments	The "lemming" locus gives rise to a dicistronic transcript. The two open reading frames (ORFs) are lmgA (upstream ORF) and lmgB (downstream ORF). The lethal, morphological and mitotic phenotypes of the Df(2L)lmg[138] deletion (which affects both open reading frames) are rescued by expression of the lmgA ORF alone and the lmgB ORF does not appear to be efficiently translated in S2 cells. (Nagy et al., 2012) Source for split of: CG18042 (FlyBase Genome Annotators, 2007) Annotation CG18042 split into CG34440 and CG34441 in release 5.2 of the genome (FlyBase Genome Annotators, 2007) annotation. (FlyBase Genome Annotators, 2007) One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by lmg (CG34440) and CG34441 (CG34441). (FlyBase Genome Annotators, 2007)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001103654 NM_001103655 NM_001273330 NM_001273331 RefSeq (Proteins) • NP_001097124 NP_001097125 NP_001260259 NP_001260260 DDBJ / EMBL / GenBank • AAF52694 ABV53652 AGB92795 AGB92796 AQ025610 CW848176 CZ476712 Entrez Gene - A searchable database of RefSeq genes. • 78 44128 UniProtKB/TrEMBL • Q9VLJ5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • FAM89 (IPR026654) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • AT07979
Linkouts
	BioGRID - A database of protein and genetic interactions • 68849 DroID - A comprehensive database of gene and protein interactions. • FBgn0085470 DRSC - Results from RNAi screens. • FBgn0085470 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0085470 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44128 modMine - Data generated by the modENCODE project. • FBgn0085470
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG34441 (Nagy et al., 2012, FlyBase Genome Annotators, 2007, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) Dromel_CG18042_FBtr0079695_lmg_mORF (Hayden and Bosco, 2008) lmgB (Nagy et al., 2012) ORF2 (Nagy et al., 2012)
Name Synonym	lemming B
Secondary FlyBase IDs
	FBan0018042 FBgn0029004
References ( 14 )
Research paper	Nagy et al., 2012, Cell Div. 7(1): 9 lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2. [FBrf0218534] Hayden and Bosco, 2008, BMC Genomics 9: 61 Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. [FBrf0204849]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Hayden and Bosco, 2008, BMC Genomics: File 1: Conserved peptide uORF and associated mORF amino acid sequences in Drosophila melanogaster. [FBrf0205942] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Ni et al., 2010.12.1, A genome-scale shRNA resource for transgenic RNAi in Drosophila. A genome-scale shRNA resource for transgenic RNAi in Drosophila. [FBrf0212437] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
FlyBase analysis	FlyBase Curators, 2010-, Gene Ontology (GO) annotation review. Gene Ontology (GO) annotation review. [FBrf0216433] FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]