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Gene Dmel\snama

General Information
Symbol	Dmel\snama	Species	D. melanogaster
Name	something that sticks like glue	Annotation symbol	CG3231
Feature type	protein_coding_gene	FlyBase ID	FBgn0086129
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	BcDNA:LD21643
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	60B9-60B11	Sequence location	2R:19,974,129..19,979,537 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene something that sticks like glue is referred to in FlyBase by the symbol Dmel\snama (CG3231, FBgn0086129). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process: apoptotic process; cell proliferation involved in compound eye morphogenesis; neurogenesis. 12 alleles are reported. The phenotypes of these alleles are annotated with: wing disc; melanotic mass. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DWNN domain; Zinc finger, CCHC retroviral-type; Zinc finger, CCHC-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1625126_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of snama. Gene sequence location is 2R:19974129..19979537.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA04049 BKN20454
FB2011_10	References Ying et al., 2011, PLoS ONE 6(9): e23863 Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60B9-60B11   Limits computationally determined from genome sequence between P{lacW}Phmk07623&P{lacW}tsrk05633 and P{EP}EP503; Left limit from in situ hybridisation (FBrf0111489) Right limit from in situ hybridisation (FBrf0111489)
Experimentally Determined Cytological Location
Cytogenetic map Notes References 60B8-60B11   (determined by in situ hybridisation)   (Spradling et al., 1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\snama for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) snama-RA FBtr0072249  NM_138040   3934   1231 snama-RB FBtr0307174     2183   494
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein snama-PA   FBpp0072158   139.0   1231   10.38     NP_611884   AAF47162 snama-PB   FBpp0298003   55.6   494   6.74
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878) Zinc finger, RING-type (IPR001841) DWNN domain (IPR014891) Zinc finger, RING/FYVE/PHD-type (IPR013083) Zinc finger, CCHC retroviral-type (IPR013084)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA391799   AA441078   AA567879   AA735628   AE013599 AAF47162   AF132177 AAD34765   AI455179   AQ026141   BG636791   BI141996   BI166335   BI230588   BI367912   BI483840   BQ103178   BT124892   CO274360   CO285136   CO298761   CO304815   CO306533   CO308691   CO331833   CO344211   CO344318   EC077539   EC079040   EC195509   EC200387   EC233956   EC237630   EC241291   EC249606   EC260673   EC260684
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9XZ21
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0086129    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0086129 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0086129 expression level Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2555) embryo 02-04hr  (2905) embryo 04-06hr  (2135) embryo 06-08hr  (1989) embryo 08-10hr  (1801) embryo 10-12hr  (1137) embryo 12-14hr  (1434) embryo 14-16hr  (1085) embryo 16-18hr  (1019) embryo 18-20hr  (660) embryo 20-22hr  (1449) embryo 22-24hr  (1333) larva L1  (621) larva L2  (568) larva L3 12hr old  (415) larva L3 puffstage 1-2  (464) larva L3 puffstage 3-6  (703) larva L3 puffstage 7-9  (932) white prepupae new  (989) white prepupae 12hr  (1078) white prepupae 24hr  (1281) pupae 2d postWPP  (1077) pupae 3d postWPP  (595) pupae 4d postWPP  (410) adult male 01day  (619) adult male 05day  (811) adult male 30day  (697) adult female 01day  (841) adult female 05day  (1715) adult female 30day  (1678) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2555) embryo 02-04hr  (2905) embryo 04-06hr  (2135) embryo 06-08hr  (1989) embryo 08-10hr  (1801) embryo 10-12hr    1137 embryo 12-14hr  1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr  1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day  (1715) adult female 30day  (1678) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0086129 expression level Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2555) embryo 02-04hr  (2905) embryo 04-06hr  (2135) embryo 06-08hr  (1989) embryo 08-10hr  (1801) embryo 10-12hr  (1137) embryo 12-14hr  (1434) embryo 14-16hr  (1085) embryo 16-18hr  (1019) embryo 18-20hr  (660) embryo 20-22hr  (1449) embryo 22-24hr  (1333) larva L1  (621) larva L2  (568) larva L3 12hr old  (415) larva L3 puffstage 1-2  (464) larva L3 puffstage 3-6  (703) larva L3 puffstage 7-9  (932) white prepupae new  (989) white prepupae 12hr  (1078) white prepupae 24hr  (1281) pupae 2d postWPP  (1077) pupae 3d postWPP  (595) pupae 4d postWPP  (410) adult male 01day  (619) adult male 05day  (811) adult male 30day  (697) adult female 01day  (841) adult female 05day  (1715) adult female 30day  (1678) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2555) embryo 02-04hr  (2905) embryo 04-06hr  2135 embryo 06-08hr  1989 embryo 08-10hr  1801 embryo 10-12hr    1137 embryo 12-14hr  1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr  1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day  1715 adult female 30day  1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2555 embryo 02-04hr    2905 embryo 04-06hr    2135 embryo 06-08hr    1989 embryo 08-10hr    1801 embryo 10-12hr    1137 embryo 12-14hr    1434 embryo 14-16hr    1085 embryo 16-18hr    1019 embryo 18-20hr    660 embryo 20-22hr    1449 embryo 22-24hr    1333 larva L1    621 larva L2    568 larva L3 12hr old    415 larva L3 puffstage 1-2    464 larva L3 puffstage 3-6    703 larva L3 puffstage 7-9    932 white prepupae new    989 white prepupae 12hr    1078 white prepupae 24hr    1281 pupae 2d postWPP    1077 pupae 3d postWPP    595 pupae 4d postWPP    410 adult male 01day    619 adult male 05day    811 adult male 30day    697 adult female 01day    841 adult female 05day    1715 adult female 30day    1678 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0086129    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0086129 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0086129 expression level Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0086129 expression level Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    78.525 Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea    40.6 Larval Carcass no informative data Adult Head no informative data Adult Eye    49.15 Adult Brain    88.9 Adult Thoracic-Abdominal Ganglion    69.8 Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    81.5 Adult Testis    46 Adult Male Accessory Gland    27.8 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea     Larval Carcass no informative data Adult Head no informative data Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    49.15   NA  Brain    88.9   78.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    69.8   NA  Crop    no informative data   no informative data  Midgut    no informative data   no informative data  Hindgut    no informative data   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    no informative data   40.6  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    81.5   NA  Testis    46   NA  Male Accessory Gland    27.8   no informative data  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086129 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3231-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele cell lethal | somatic clone snamaPX1 lethal, with Scer\GAL41407 snamaGD10853 lethal | embryonic stage 16 | recessive snamarQ313 lethal | embryonic stage | recessive snamaPX1 lethal | heat sensitive, with Scer\GAL4en-e16E snamaScer\UAS.cJa lethal | pupal stage, with Scer\GAL4pnr-MD237 snamaGD10853 lethal | pupal stage | recessive snama1 lethal | recessive snamarQ313 viable snamac00805 Sterility Allele fertile snamac00805 Other Phenotypes Allele increased cell death snamarQ313 neuroanatomy defective | larval stage, with Scer\GAL41407 snamaGD10853 visible | somatic clone snamaPX1 Phenotype manifest in Allele adult abdomen | dorsal, with Scer\GAL4en-e16E snamaScer\UAS.cJa embryonic/larval neuroblast | larval stage, with Scer\GAL41407 snamaGD10853 eye | somatic clone snamaPX1 ganglion mother cell | larval stage, with Scer\GAL41407 snamaGD10853 melanotic mass, with Scer\GAL4en-e16E snamaScer\UAS.cJa wing | posterior compartment, with Scer\GAL4en-e16E snamaScer\UAS.cJa wing disc, with Scer\GAL4en-e16E snamaScer\UAS.cJa
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of snama Class Mutagen Stocks Known lesion snamac00805 piggyBac transposase 2 -- snama1 ethyl methanesulfonate 1 -- snamaEY03620 P-element activity 1 -- snamaPX1 loss of function allele Delta2-3 1 Yes snamarQ313 P-element activity 1 Yes snamaunspecified 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of snama Class Mutagen Stocks Known lesion snama+t14.7 in vitro construct - genomic fragment 1 Yes snamaGD10853 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes snamaScer\UAS.cJa in vitro construct - regulatory fusion 0 Yes snamat8 in vitro construct - genomic fragment 0 Yes snamatmut3 in vitro construct 0 Yes snamatmut4 in vitro construct - deletion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6081 (Ryder, 2004.4.26)
Not disrupted in	Df(2R)bwVDe2LPxKR (Spradling et al., 1999) Df(2R)or-BR11 (Spradling et al., 1999, BDGP Project Members, 1994-1999) In(2LR)ltG10LBR27R (BDGP Project Members, 1994-1999) In(2LR)Px4 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10853} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}snamaEY03620 NA insertion of enhancer trap P{PZ}snamarQ313 No miscellaneous insertions PBac{PB}snamac00805 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
apoptotic process inferred from mutant phenotype (Mather et al., 2005) cell proliferation involved in compound eye morphogenesis inferred from mutant phenotype (Jones et al., 2006) neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR013084 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001878, InterPro:IPR013084, InterPro:IPR014891 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from electronic annotation with InterPro:IPR014891 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions snama allele Gene References unspecified dpp (Jones et al., 2006) hh (Jones et al., 2006) N (Jones et al., 2006)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63436 DroID - A comprehensive database of gene and protein interactions. • FBgn0086129 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37857
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs	Dpse\GA16823
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AGAP011217-PA Anopheles gambiae (mosquito) XP_001120561.1 Apis mellifera (honey bee) XP_001945968.1 Acyrthosiphon pisum (pea aphid) At5g47430.1 Arabidopsis thaliana (wall cress) 92283 Batrachochytrium dendrobatidis (chytrid fungus) 118654 Branchiostoma floridae (lancelet) XP_001897522.1 Brugia malayi (roundworm nematode) BGIBMGA007244-PA Bombyx mori (silk worm) ENSBTAP00000044535 Bos taurus (bovine) CN02242 Caenorhabditis brenneri (small nematode) CBP26112 Caenorhabditis briggsae (nematode) ENSCAFP00000025895 Canis familiaris (dog) Chro.30391 Cryptosporidium hominis (obligate parasite) ENSCINP00000020173 Ciona intestinalis (sea squirt) JA15725 Caenorhabditis japonica (nematode) CMQ079C Cyanidioschyzon merolae (red alga) cn12190 Cryptococcus neoformans (yeast-like fungus) cgd3_3460 Cryptosporidium parvum (protozoan parasite) CPIJ008053 Culex pipens (mosquito) RP29541 Caenorhabditis remanei (nematode) DDB0215292 Dictyostelium discoideum (amoeba) 309825 Daphnia pulex (daphnia) ENSGALP00000009720 Gallus gallus (chicken) 189827 Hypsipyla robusta (cedar shoot borer) ENSP00000317872 Homo sapiens (human) 235816 Lottia gigantea (owl limpet) ENSMODP00000020399 Monodelphis domestica (gray opossum) ENSMMUP00000020915 Macaca mulatta (rhesus monkey) ENSMUSP00000049528 Mus musculus (house mouse) XP_001603499.1 Nasonia vitripennis (wasp) ENSOANP00000012221 Ornithorynchus anatinus (platypus) ENSORLP00000010825 Oryzias latipes (japanese killifish) LOC_Os10g29560.1 Oryza sativa (asian rice) 35767 Ostreococcus tauri (green alga) PHUM010567-PA Pediculus humanus (human body louse) PP28080 Pristionchus pacificus (nematode) 231964 Physcomitrella patens (moss) ENSPPYP00000008142 Pongo pygmaeus (orangutan) 80189 Phytophthora ramorum (sudden oak death pathogen) 131714 Phytophthora sojae (root rot pathogen) ENSPTRP00000013482 Pan troglodytes (chimpanzee) ENSRNOP00000036139 Rattus norvegicus (norway rat) 5048837 Sorghum bicolor (sorghum) Smp_039640.2 Schistosoma mansoni (trematode parasite) 63677 Trichoplax adhaerens (metazoa) XP_973377.2 Tribolium castaneum (red flour beetle) 22487 Thalassiosira pseudonana (marine diatom) 96.m00172 Tetrahymena thermophila (ciliate protozoa) 89100.m00029 Trichomonas vaginalis (parasitic flagellated protozoan) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13917 LH22745 FBgn0231986 FBgn0223904 FBgn0207566 FBgn0173213 JGI_V11_309825 FBgn0076837 FBgn0149275 FBgn0143411 FBgn0129186 FBgn0115097 FBgn0088411 CPIJ008053 BGIBMGA007244 ACYPI003645 AGAP011217 AAEL002729 PB23832 PHUM515430 GLEAN_06501
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	35563 snama1/CyO 35566 w1118; P{mnm+t14.7}2A/CyO 10299 w1118; PBac{PB}snamac00805 15907 y1 w67c23; P{EPgy2}snamaEY03620 35565 w1118; P{neoFRT}42D snamaPX1/T(2;3)TSTL, CyO: TM6B, Tb1 35564 w1118; P{neoFRT}42D P{PZ}snamarQ313/T(2;3)TSTL, CyO: TM6B, Tb1
Harvard	- PBac{PB}snamac00805
VDRC	v34515 w1118; P{GD10853}v34515/TM3
Genomic Clones ( 1 )
	BACR27M17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 31 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD21643
Other clones	MIP16350
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	HL01930 LD11573 LD15859 RE06431 RE14296 RE53784 RE66790 SD14576 SD15980
Other clones	43048 60103 120955 148827 156312 194045 214449.76 214577.47 CK01.56B.E11 CK01.58A.G7 EK113901 EK168321 EK173817 EK246304 EK251353 EK259126 EK301806 EP18848 EP19042 UUGC0576
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0086129 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37857
Antibody Information
Other Information
Discoverer
Etymology
	Because mutant clones in the developing eye posterior to the morphogenetic furrow differentiate as apparently perfect, yet tiny copies of their wild-type twin spots, the gene is named "mini-me" (Myers M. and M. McCullers, 1999, Austin Powers: The Spy Who Shagged Me. New Line Cinema, Los Angeles). (Jones et al., 2006)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: BcDNA:LD21643 CG3231 (Wang, 1999.11) Source for identity of: mnm CG3231 (Jones et al., 2006) Source for identity of: mnm l(2)rQ313 (Jones et al., 2006)
Source for database merge of	Source for merge of: l(2)rQ313 CG3231 (Jones et al., 2006)
Additional comments
Other Comments
	mnm appears to be required in proliferative cells, but not in postmitotic cells, in the developing eye. (Jones et al., 2006)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138040 RefSeq (Proteins) • NP_611884 DDBJ / EMBL / GenBank • AA735628 AAD34765 AAF47162 AF132177 AI455179 AQ026141 Entrez Gene - A searchable database of RefSeq genes. • 37857 UniProtKB/TrEMBL • Q9XZ21
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCHC-type (IPR001878) Zinc finger, RING-type (IPR001841) DWNN domain (IPR014891) Zinc finger, RING/FYVE/PHD-type (IPR013083) Zinc finger, CCHC retroviral-type (IPR013084)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63436 DroID - A comprehensive database of gene and protein interactions. • FBgn0086129 DRSC - Results from RNAi screens. • FBgn0086129 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086129 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3231-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0086129 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37857 InParanoid A subset of ortholog calls from InParanoid. • AGAP011217-PA Anopheles gambiae (mosquito) XP_001120561.1 Apis mellifera (honey bee) XP_001945968.1 Acyrthosiphon pisum (pea aphid) At5g47430.1 Arabidopsis thaliana (wall cress) 92283 Batrachochytrium dendrobatidis (chytrid fungus) 118654 Branchiostoma floridae (lancelet) XP_001897522.1 Brugia malayi (roundworm nematode) BGIBMGA007244-PA Bombyx mori (silk worm) ENSBTAP00000044535 Bos taurus (bovine) CN02242 Caenorhabditis brenneri (small nematode) CBP26112 Caenorhabditis briggsae (nematode) ENSCAFP00000025895 Canis familiaris (dog) Chro.30391 Cryptosporidium hominis (obligate parasite) ENSCINP00000020173 Ciona intestinalis (sea squirt) JA15725 Caenorhabditis japonica (nematode) CMQ079C Cyanidioschyzon merolae (red alga) cn12190 Cryptococcus neoformans (yeast-like fungus) cgd3_3460 Cryptosporidium parvum (protozoan parasite) CPIJ008053 Culex pipens (mosquito) RP29541 Caenorhabditis remanei (nematode) DDB0215292 Dictyostelium discoideum (amoeba) 309825 Daphnia pulex (daphnia) ENSGALP00000009720 Gallus gallus (chicken) 189827 Hypsipyla robusta (cedar shoot borer) ENSP00000317872 Homo sapiens (human) 235816 Lottia gigantea (owl limpet) ENSMODP00000020399 Monodelphis domestica (gray opossum) ENSMMUP00000020915 Macaca mulatta (rhesus monkey) ENSMUSP00000049528 Mus musculus (house mouse) XP_001603499.1 Nasonia vitripennis (wasp) ENSOANP00000012221 Ornithorynchus anatinus (platypus) ENSORLP00000010825 Oryzias latipes (japanese killifish) LOC_Os10g29560.1 Oryza sativa (asian rice) 35767 Ostreococcus tauri (green alga) PHUM010567-PA Pediculus humanus (human body louse) PP28080 Pristionchus pacificus (nematode) 231964 Physcomitrella patens (moss) ENSPPYP00000008142 Pongo pygmaeus (orangutan) 80189 Phytophthora ramorum (sudden oak death pathogen) 131714 Phytophthora sojae (root rot pathogen) ENSPTRP00000013482 Pan troglodytes (chimpanzee) ENSRNOP00000036139 Rattus norvegicus (norway rat) 5048837 Sorghum bicolor (sorghum) Smp_039640.2 Schistosoma mansoni (trematode parasite) 63677 Trichoplax adhaerens (metazoa) XP_973377.2 Tribolium castaneum (red flour beetle) 22487 Thalassiosira pseudonana (marine diatom) 96.m00172 Tetrahymena thermophila (ciliate protozoa) 89100.m00029 Trichomonas vaginalis (parasitic flagellated protozoan) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37857 modMine - Data generated by the modENCODE project. • FBgn0086129 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13917 LH22745 FBgn0231986 FBgn0223904 FBgn0207566 FBgn0173213 JGI_V11_309825 FBgn0076837 FBgn0149275 FBgn0143411 FBgn0129186 FBgn0115097 FBgn0088411 CPIJ008053 BGIBMGA007244 ACYPI003645 AGAP011217 AAEL002729 PB23832 PHUM515430 GLEAN_06501
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	BcDNA:LD21643 (Giot et al., 2003, ) BCDNA:LD21643 (Mather et al., 2005) CG3231 (Jones et al., 2006, Mather et al., 2005, Ying et al., 2011) l(2)rQ313 (Jones et al., 2006, ) mnm (Jones et al., 2006) snama (Neumüller et al., 2011) SNAMA (Mather et al., 2005)
Name Synonym	CG3231   lethal (2) rQ313   mini-me (Jones et al., 2006) something that sticks like glue (Mather et al., 2005)
Secondary FlyBase IDs
	FBgn0027522 FBgn0028594
References ( 19 )
Research paper	Neumüller et al., 2011, Cell Stem Cell 8(5): 580--593 Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi. [FBrf0213621] Ying et al., 2011, PLoS ONE 6(9): e23863 Comprehensively Surveying Structure and Function of RING Domains from Drosophila melanogaster. [FBrf0215242] Jones et al., 2006, Genetics 173(2): 793--808 Characterization of Drosophila mini-me, a gene required for cell proliferation and survival. [FBrf0193720] Mather et al., 2005, Biochim. biophys. Acta 1727(3): 169--176 SNAMA, a novel protein with a DWNN domain and a RING finger-like motif: a possible role in apoptosis. [FBrf0187177] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Supplementary material	Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Curated genome annotation	Wang, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126695]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]