Gene Dmel\CG6084

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General Information

Symbol

Dmel\CG6084

Species

D. melanogaster

Name

CG6084

Annotation symbol

CG6084

Feature type

protein_coding_gene

FlyBase ID

FBgn0086254

Created / Updated

2007-06-14/2007-06-14

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

68C15-68D

Sequence location

3L:11,613,633..11,617,481 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG6084 (FBgn0086254). It has the cytological map location 68C15-68D. Its sequence location is 3L:11613633..11617481. Its molecular function is described as aldehyde reductase activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

68C15-68D

Limits computationally determined from genome sequence between P{PZ}l(3)01239⁰¹²³⁹&P{lacW}l(3)01239^j9B4 and P{PZ}CycA⁰²⁴⁶¹&P{PZ}CycA⁰³⁹⁴⁶; Left limit from in situ hybridisation (FBrf0071734) Right limit from in situ hybridisation (FBrf0071734)

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

68D-68D

(determined by in situ hybridisation)

(Louis et al., 1997)

68D-68D

(determined by in situ hybridisation)

(EDGP Project Members, 1994-)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG6084 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG6084-RA

FBtr0076139

1105

316

CG6084-RB

FBtr0076138

1355

350

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG6084-PA

FBpp0075870

35.9

316

6.63

AAF50039

CG6084-PB

FBpp0075869

40.1

350

8.03

AAN11878

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Aldo/keto reductase (IPR001395)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

(BDGP Project Members, 2000-)

(Oliver, 2001.8.16)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Sterility

Allele

fertile

Phenotype manifest in

Allele

Classical Alleles ( 6 )

For All Classical Alleles Show

Allele of CG6084	Mutagen	Stocks	Known lesion
CG6084^EY07011	P-element activity	1	--
CG6084^G00112	P-element activity	1	Yes
CG6084^PL00034	P-element activity	1	--
CG6084^d00405	P-element activity	1	--
CG6084^d07635	P-element activity	0	--
CG6084^f00350	piggyBac transposase	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG6084	Class	Mutagen	Stocks	Known lesion
CG6084^GD11810		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful deficiency

Df(3L)vin3

Useful duplication

Dp(3;3)M67C⁺4

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD11810}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{WH}CG6084^f00350

P{PTT-GC}CG6084^G00112

insertion of enhancer trap binary system

PBac{GAL4D,EYFP}CG6084^PL00034

insertion of mobile activating element

P{EPgy2}CG6084^EY07011

P{XP}CG6084^d00405

P{XP}CG6084^d07635

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 1 )

Molecular Function

CV term

Evidence

References

aldehyde reductase activity

inferred from sequence or structural similarity with UniProtKB:P15122

(FlyBase, 1992-)

inferred from sequence or structural similarity

(EDGP Project Members, 1994-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

STS

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG6084 allele

Gene

References

External Data

Linkouts

Orthologs

Genome-wide drosophilid orthologs

Curated drosophilid orthologs

Dpse\GA19342

Dyak\GE20195

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 7 )

Harvard

P{XP}CG6084^d00405

PBac{WH}CG6084^f00350

VDRC

v27551

w¹¹¹⁸ P{GD11810}v27551

v27552

w¹¹¹⁸ P{GD11810}v27552

Bloomington

6835

w¹¹¹⁸; P{PTT-GC}CG6084^G00112

16777

y¹ w^67c23; P{EPgy2}CG6084^EY07011

19594

w^*; PBac{GAL4D,EYFP}CG6084^PL00034 P{FRT(w^hs)}2A P{neoFRT}82B

Genomic Clones ( 2 )

cDNA Clones ( 62 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG6084 ESTS:34F4T

(FlyBase, 1996-)

Additional comments

Comments About Role

The existence of this gene is tentative, and is based on a match of an STS sequence from a European Drosophila Genome Mapping Project cosmid.

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Aldo/keto reductase (IPR001395)

Linkouts

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

34F4T

(Louis et al., 1997)

CG6084

(FlyBase, 1996-, )

ESTS:34F4T

Name Synonym

CG6084

ESTS:34F4T

Secondary FlyBase IDs

FBgn0036182
FBgn0017641

References ( 19 )

Research paper

Blanchette et al., 2005, Genes Dev. 19(11): 1306--1314: Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila. [FBrf0187590]
Nakahara et al., 2005, Proc. Natl. Acad. Sci. USA 102(34): 12023--12028: Targets of microRNA regulation in the Drosophila oocyte proteome. [FBrf0188268]
Gong et al., 2004, Development 131(3): 643--656: Drosophila ventral furrow morphogenesis: a proteomic analysis. [FBrf0167535]
de Morais Guedes et al., 2003, Biochem. biophys. Res. Commun. 312(3): 545--554: Drosophila melanogaster larval hemolymph protein mapping. [FBrf0167337]
Morin et al., 2001, Proc. Natl. Acad. Sci. USA 98(26): 15050--15055: A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. [FBrf0141725]
Louis et al., 1997, Gene 195(2): 187--193: One-hundred and five new potential Drosophila melanogaster genes revealed through STS analysis. [FBrf0098301]

Supplementary material

Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Haecker et al., 2004, Haecker insertions.: Haecker insertions. [FBrf0184338]
Cooley et al., 2002.10-2003.5, GFP Protein Trap Insertion Lines.: GFP Protein Trap Insertion Lines. [FBrf0161605]
Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348).: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]
FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection.: Genomic mapping of Exelixis insertion collection. [FBrf0184340]
Gene Disruption Project members, 2001-, [title not yet available]: [title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]
EDGP Project Members, 1994-, European Drosophila Genome Mapping Project.: European Drosophila Genome Mapping Project. [FBrf0071734]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]

Curated genome annotation

Zhu, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126704]