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Gene Dmel\poly

General Information
Symbol	Dmel\poly	Species	D. melanogaster
Name	poly	Annotation symbol	CG9829
Feature type	protein_coding_gene	FlyBase ID	FBgn0086371
Gene Model Status	Current	Stock availability	8 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	87E7-87E8	Sequence location	3R:9,187,538..9,192,632 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene poly is referred to in FlyBase by the symbol Dmel\poly (CG9829, FBgn0086371). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: insulin receptor binding. There is experimental evidence that it is involved in the biological process: insulin receptor signaling pathway; oocyte microtubule cytoskeleton polarization; melanotic encapsulation of foreign target. 20 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; egg chamber; melanotic mass; nucleus. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Uncharacterised protein family UPF0405. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, inseminated spermatheca, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1627983_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of poly. Gene sequence location is 3R:9187538..9192632.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	l(3)SG67 Homozygotes pupariate, but do not metamorphose; imaginal discs never exceed in size those of late second-instar larvae. Mutant eye-antennal and wing discs transplanted into adult wild-type female abdomens are never recovered after seven days in culture; they decrease in size and disappear during first three days. Mutant larvae permit reduced growth of implanted wild-type discs and do not interfere with their subsequent development in normal hosts (Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70). Larval ganglion cells exhibit extremely low mitotic index and weak effects on chromosome condensation; chromosomes thin and elongated (Gatti and Baker, 1989, Genes Dev. 3: 438-53).
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 87E7-87E8   Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338)
Experimentally Determined Cytological Location
Cytogenetic map Notes References 87E5-87E10   (determined by in situ hybridisation)   (Deak, 1999.12.22) 87E7-87E8   (determined by in situ hybridisation)   (Spradling et al., 1999) 87E5-87E10   (determined by in situ hybridisation)   (Szeged Stock Center, 1998-) 87E5-87E10   (determined by in situ hybridisation)   (Deak et al., 1997) 87E5-87E6   (determined by in situ hybridisation)   (Heck, 1995) 87E7-87E8   (determined by in situ hybridisation)   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\poly for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Annotated transcripts do not represent all supported alternative splices within 5' UTR. Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) poly-RA FBtr0082772  NM_079619   1157   251 poly-RB FBtr0303265  NM_001202286   1314   251
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein poly-PA   FBpp0082240   27.9   251   6.91     NP_524343   AAF54931 poly-PB   FBpp0292357   27.9   251   6.91     NP_001189215   ADV37306
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised protein family UPF0405 (IPR018627)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438416   AA438632   AA697896   AE014297 AAF54931   AE014297 ADV37306   AF234629 AAF40432   AI947101   AQ026205   AQ073132   AW942245   BE975672   BE975673   BE977163   BF485881   BF492801   BF493645   BG635186   BG639566   BI609363   BI609892   BI621130   BP543637   BP543638   BQ103509   BQ103593   BT011120   BT081367   CK604228   CK604229   CO267308   CO301077   CO316151   CO320926   CO321704   CZ467224   CZ467225   CZ473836   CZ480506   CZ480526   CZ484016   CZ488842   CZ488843   DN154332   EC074334   EC222928   EC227716   EC236481
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VFW4 Q9NH01
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, inseminated spermatheca, adult testis. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules  (832.5) Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca  509.9 Adult Ovary    471.5 Adult Testis  (679.2) Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules  (832.5) Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca  509.9 Adult Ovary    471.5 Adult Testis  679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    375.475 Larval Midgut    145.7 Larval Hindgut    224.1 Larval Malpighian Tubules    334.7 Larval Fat Body    406.8 Larval Salivary Gland    390.5 Larval Trachea    363.175 Larval Carcass    214.425 Adult Head    273.2 Adult Eye    226.225 Adult Brain    292.4 Adult Thoracic-Abdominal Ganglion    298.7 Adult Crop    297.1 Adult Midgut    224.1 Adult Hindgut    253.3 Adult Malpighian Tubules    832.5 Adult Fat Body    249.8 Adult Salivary Gland    348.4 Adult Heart    319.125 Adult VirginFemale Spermatheca    447 Adult InseminatedFemale Spermatheca    509.9 Adult Ovary    471.5 Adult Testis    679.2 Adult Male Accessory Gland    385.7 Adult Carcass    283.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    273.2   NA  Eye    226.225   NA  Brain    292.4   375.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    298.7   NA  Crop    297.1   145.7  Midgut    224.1   224.1  Hindgut    253.3   334.7  Malpighian Tubules    832.5   406.8  Fat Body    249.8   390.5  Salivary Gland    348.4   NA  Heart    319.125   363.175  Trachea    NA   NA  VirginFemale Spermatheca    447   NA  InseminatedFemale Spermatheca    509.9   NA  Ovary    471.5   NA  Testis    679.2   NA  Male Accessory Gland    385.7   214.425  Carcass    283.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8  (27) carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male  (52) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8  27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male  (52) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    12 central nervous system, pupae P8    8 head, virgin 1-day female    10 head, virgin 4-day female    6 head, virgin 20-day female    9 head, mated 1-day female    8 head, mated 4-day female    7 head, mated 20-day female    6 head, mated 1-day male    9 head, mated 4-day male    9 head, mated 20-day male    12 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    9 fat body, larvae L3 wandering    9 fat body, white prepupae    15 fat body, pupae P8    27 carcass, larvae L3 wandering    12 carcass, 1-day adult    9 carcass, 4-day adult    10 carcass, 20-day adult    9 ovary, virgin 4-day female    25 ovary, mated 4-day female    18 testis, mated 4-day male    52 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (55) embryo 02-04hr  (53) embryo 04-06hr  (64) embryo 06-08hr  (46) embryo 08-10hr  (41) embryo 10-12hr  (46) embryo 12-14hr  (31) embryo 14-16hr  (30) embryo 16-18hr  (28) embryo 18-20hr  (27) embryo 20-22hr  (28) embryo 22-24hr  (36) larva L1  (31) larva L2  (31) larva L3 12hr old    24 larva L3 puffstage 1-2  26 larva L3 puffstage 3-6  (33) larva L3 puffstage 7-9  (42) white prepupae new  (40) white prepupae 12hr  (41) white prepupae 24hr  (48) pupae 2d postWPP  (45) pupae 3d postWPP  (39) pupae 4d postWPP  (40) adult male 01day  (48) adult male 05day  (55) adult male 30day  (60) adult female 01day  (41) adult female 05day  (42) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (55) embryo 02-04hr  (53) embryo 04-06hr  (64) embryo 06-08hr  (46) embryo 08-10hr  (41) embryo 10-12hr  (46) embryo 12-14hr  31 embryo 14-16hr  30 embryo 16-18hr  28 embryo 18-20hr  27 embryo 20-22hr  28 embryo 22-24hr  (36) larva L1  31 larva L2  31 larva L3 12hr old    24 larva L3 puffstage 1-2  26 larva L3 puffstage 3-6  (33) larva L3 puffstage 7-9  (42) white prepupae new  (40) white prepupae 12hr  (41) white prepupae 24hr  (48) pupae 2d postWPP  (45) pupae 3d postWPP  (39) pupae 4d postWPP  (40) adult male 01day  (48) adult male 05day  (55) adult male 30day  (60) adult female 01day  (41) adult female 05day  (42) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    55 embryo 02-04hr    53 embryo 04-06hr    64 embryo 06-08hr    46 embryo 08-10hr    41 embryo 10-12hr    46 embryo 12-14hr    31 embryo 14-16hr    30 embryo 16-18hr    28 embryo 18-20hr    27 embryo 20-22hr    28 embryo 22-24hr    36 larva L1    31 larva L2    31 larva L3 12hr old    24 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    33 larva L3 puffstage 7-9    42 white prepupae new    40 white prepupae 12hr    41 white prepupae 24hr    48 pupae 2d postWPP    45 pupae 3d postWPP    39 pupae 4d postWPP    40 adult male 01day    48 adult male 05day    55 adult male 30day    60 adult female 01day    41 adult female 05day    42 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21  (42) wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1  (30) CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21  (42) wing disc ML-DmD32    14 haltere disc ML-DmD17-c3  (36) eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1  30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2  (34) tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    22 Schneider line 2 Sg4    16 embryonic 1182-4H    12 embryonic GM2    18 embryonic Kc167    13 embryonic S1    18 embryonic S3    18 leg disc CME L1    12 wing disc CME-W2    19 wing disc ML-DmD8    19 wing disc ML-DmD9    19 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    42 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    36 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    21 mixed discs ML-DmD4-c1    30 CNS ML-DmBG1-c1    24 CNS ML-DmBG2-c2    34 tumorous blood cells mbn2    11 ovary fGS/OSS    18 ovary OSC    14 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    7 cold shock, 4-day adult    6 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    19 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    17 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    8 Zinc 4.5 mM 48 hrs, 4-day adult    10 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    11 Caffeine 1.5 mg/ml 4 hrs, larvae L3    14 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    17 Caffeine 25 mg/ml 48 hrs, 4-day adult    8 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    22 Rotenone 2 μg 12 hrs, larvae L3    20 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_21 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086371 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9829-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | larval stage poly1 lethal | larval stage | recessive poly1 lethal | recessive poly05137 polyS008131b lethal | third instar larval stage poly05137 partially lethal - majority die | recessive polyS008131b Sterility Allele female sterile poly2 Other Phenotypes Allele developmental rate defective poly2 developmental rate defective (with poly1) poly2 developmental rate defective (with poly2) poly1 developmental rate defective | third instar larval stage poly05137 immune response defective | larval stage poly05137 increased cell death poly2 increased cell death (with poly1) poly2 increased cell death (with poly2) poly1 increased cell death | somatic clone | third instar larval stage poly05137 increased cell death | third instar larval stage poly05137 melanotic mass phenotype poly1 poly2 melanotic mass phenotype | third instar larval stage poly05137 visible poly2 visible, with Scer\GAL4GMR.PU polyScer\UAS.cBa Phenotype manifest in Allele egg chamber poly2 egg chamber (with poly1) poly2 egg chamber (with poly2) poly1 embryonic/larval brain | third instar larval stage poly05137 embryonic/larval fat body | third instar larval stage poly05137 embryonic/larval salivary gland | third instar larval stage poly05137 eye, with Scer\GAL4GMR.PU polyScer\UAS.cBa imaginal disc | somatic clone | third instar larval stage poly05137 imaginal disc | third instar larval stage poly05137 melanotic mass poly1 melanotic mass | third instar larval stage poly05137 neuroblast | third instar larval stage poly05137 nucleus poly1 nurse follicle cell | germline clone | oogenesis stage S5 poly2 ring gland | third instar larval stage poly05137 wing margin poly2 wing margin (with poly1) poly2 wing margin (with poly2) poly1
Classical Alleles ( 16 )
For All Classical Alleles Show
Allele of poly Class Mutagen Stocks Known lesion poly05137 amorphic allele - molecular evidence P-element activity 1 Yes polyc01091 1 -- polyd04286 P-element activity 1 -- polye02734 piggyBac transposase 1 -- polyEY03597 1 -- polyf01552 piggyBac transposase 1 -- polyf06191 piggyBac transposase 1 -- polyNP0135 1 -- poly1 PM hybrid dysgenesis 0 Yes poly2 0 -- polyc01516 piggyBac transposase 0 -- polyc01517 piggyBac transposase 0 -- polye02755 piggyBac transposase 0 -- polyEP3703 P-element activity 0 -- polyF332.1 Delta2-3 0 Yes polyS008131b Delta2-3 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of poly Class Mutagen Stocks Known lesion polyGD14692 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes polyScer\UAS.cBa in vitro construct - regulatory fusion 0 Yes polyScer\UAS.P\T.cKa in vitro construct - regulatory fusion 0 Yes polyScer\UAS.P\T.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6168 (Ryder, 2004.4.26) Df(3R)l26c (Szeged Stock Center, 1998-)
Not disrupted in	Df(3R)ry615 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14692} NA P{UAS-poly.B} NA P{UASp-poly.eGFP} NA P{UASp-poly.K} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}polyS008131b No P{PZ}poly05137 No insertion of mobile activating element P{EP}polyEP3703 NA P{EPgy2}Dic1EY03597 NA P{Mae-UAS.6.11}polyF332.1 NA P{XP}polyd04286 NA miscellaneous insertions P{}poly1 NA PBac{5HPw+}Dic1A150 NA PBac{PB}polyc01091 NA PBac{PB}polyc01516 NA PBac{PB}polyc01517 NA PBac{RB}polye02734 NA PBac{RB}polye02755 NA PBac{WH}polyf01552 NA PBac{WH}polyf06191 NA insertion of enhancer trap binary system P{GawB}polyNP0135 No
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
insulin receptor binding inferred from direct assay (Bolukbasi et al., 2012)
Biological Process
CV term Evidence References
insulin receptor signaling pathway inferred from mutant phenotype (Bolukbasi et al., 2012) melanotic encapsulation of foreign target inferred from mutant phenotype (Howell et al., 2012) oocyte microtubule cytoskeleton polarization inferred from direct assay (Klusza and Deng, 2010)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
poly - CG15643 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - CG2034 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - CG3609 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - CG4611 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - CG6907 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Fmr1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Gs1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Imp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - InR anti bait coimmunoprecipitation, peptide massfingerprinting (Bolukbasi et al., 2012) poly - NHP2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Ns1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Rheb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - Rpt2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - eIF4AIII anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - mRpS24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - mRpS28 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - mts anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) poly - tyn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions poly allele Gene References unspecified os (Mukherjee et al., 2006)
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0086371 DroID - A comprehensive database of gene and protein interactions. • FBgn0086371 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41641
Orthologs
OrthoDB Orthologs (28) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6RV3BP Dipteran inclusive ortholog search EOG6GF3QH Insect inclusive ortholog search EOG6J6QNJ Arthropod inclusive ortholog search EOG67H46P Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6RV3BP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\poly     Drosophila simulans   Dsim\GD20507     Drosophila sechellia   Dsec\GM25947     Drosophila erecta   Dere\GG17062     Drosophila yakuba   Dyak\GE24450     Drosophila ananassae   Dana\GF17390     Drosophila pseudoobscura pseudoobscura   Dpse\GA22063     Drosophila persimilis   Dper\GL23070     Drosophila willistoni   Dwil\GK13353     Drosophila virilis   Dvir\GJ10747     Drosophila mojavensis   Dmoj\GI23250     Drosophila grimshawi   Dgri\GH18551
Orthologs in non-Drosophila Dipterans (EOG6GF3QH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012624   Anopheles gambiae Malaria mosquito  Agam\AGAP003075
Orthologs in non-Dipteran Insects (EOG6J6QNJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016845   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH26298   Atta cephalotes Leafcutter ant  Acep\ACEP17267   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13486   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21254   Linepithema humile Argentine ant  Lhum\LH16924   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17812   Solenopsis invicta Red fire ant  Sinv\SINV20433   Acyrthosiphon pisum Pea aphid  Apim\ACYPI31067   Bombyx mori Silkmoth  Bmor\LOC692989   Pediculus humanus Human body louse  Phum\PHUM235420   Tribolium castaneum Red flour beetle  Tcas\TC006496
Orthologs in non-Insect Arthropods (EOG67H46P)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_220513   Ixodes scapularis Deer tick  Isca\ISCW009787
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	15659 y1 w67c23; P{EPgy2}Dic1EY03597 polyEY03597 11648 ry506 P{PZ}poly05137/TM3, ryRK Sb1 Ser1
Harvard	- P{XP}polyd04286 - PBac{PB}polyc01091 - PBac{RB}polye02734 - PBac{WH}polyf01552 - PBac{WH}polyf06191
Kyoto	103537 y* w*; P{GawB}polyNP0135 / TM6, P{UAS-lacZ.UW23-1}UW23-1
Genomic Clones ( 2 )
	BACR05K08 BACR06H18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 30 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD12690
Other clones	DPiM_LD12690 MIP09035
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01213 AT01961 AT19955 AT31690 HL03426 LD12950 RH14136 RH14739 RH52428 SD02593
Other clones	54598 59786 97116 184068 bs35b03 bs45a12 bs60e04 EK149403 EK180026 EK186221 EK219135 EK263804 EK288817 FGC021E10 UT01020 UUGC0916 UUGC1001
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0086371 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41641
Antibody Information
	polyclonal (Bolukbasi et al., 2012)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: l(3)05137 l(3)S008131 (Deak, 1999.12.22) Source for merge of: poly l(3)05137 (Mukherjee et al., 2006)
Additional comments
Other Comments
	Identification: isolated in a mosaic screen in which posterior stau localization is disrupted in stage 9 female germ-line clones. (Klusza and Deng, 2006) dsRNA made from templates generated with primers directed against this gene used in a cell-based RNAi assay to identify components or modifiers of the JAK/STAT pathway. (Mukherjee et al., 2006) Lethal complementation group identified by insertion of a P{lacW} element in the 86E-87F region. (Deak et al., 1997) Wild type poly gene product may act as a tumour suppressor. (Heck, 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079619 NM_001202286 RefSeq (Proteins) • NP_524343 NP_001189215 DDBJ / EMBL / GenBank • AA438416 AAF40432 AAF54931 ADV37306 AF234629 AI947101 AQ026205 AQ073132 AW942245 CZ467224 CZ467225 CZ473836 CZ480506 CZ480526 CZ484016 CZ488842 CZ488843 Entrez Gene - A searchable database of RefSeq genes. • 41641 UniProtKB/TrEMBL • Q9NH01 Q9VFW4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Uncharacterised protein family UPF0405 (IPR018627)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0086371 DroID - A comprehensive database of gene and protein interactions. • FBgn0086371 DRSC - Results from RNAi screens. • FBgn0086371 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086371 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9829-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0086371 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41641 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41641 modMine - Data generated by the modENCODE project. • FBgn0086371
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	0081/31 (Deak et al., 1997) CG9829 (Bolukbasi et al., 2012, Howell et al., 2012) did (Vass, 2000.2.15) did/alt1 (Mukherjee et al., 2006) l(3)05137   l(3)S008131 (Szeged Stock Center, 1998-, ) poly (Nakahara and Carthew, 2004, Giot et al., 2003, Gene Disruption Project members and Exelixis, 2005, FlyBase, 1992-, Klusza and Deng, 2007, Arancio et al., 2010, Bolukbasi et al., 2012, Klusza and Deng, 2010, Howell et al., 2012) unnamed (Deak et al., 1997)
Name Synonym	lethal (3) 05137   poly (Heck, 1995, Klusza and Deng, 2010)
Secondary FlyBase IDs
	FBgn0002506 FBgn0004732 FBgn0010858 FBgn0014374 FBgn0023020 FBgn0038141
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 4 ) Review  ( 1 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 6 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 1 ) Stock list  ( 1 )
Recent research papers ( 2 )
	Bolukbasi et al., 2012, Open Biol. 2(1): 110031 Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling. [FBrf0218466] Howell et al., 2012, Immunogenetics 64(2): 155--161 A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response. [FBrf0217123] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...